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Antineoplastic Side Effects

Common Antineoplastic Side Effects


The most commonly reported Antineoplastic side effects (click to view or check a box to report):

Dyspnoea (10)
Muscular Weakness (5)
Death (5)
Coordination Abnormal (5)
Confusional State (5)
Fatigue (4)
Renal Impairment (4)
Febrile Neutropenia (4)
Hyponatraemia (3)
Dehydration (3)
Mucosal Inflammation (3)
Chills (3)
Weight Decreased (3)
Nausea (3)
Therapeutic Response Decreased (3)
White Blood Cell Count Decreased (3)
Neoplasm Progression (3)
Oral Pain (2)
Peritoneal Carcinoma (2)
Pain (2)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

Antineoplastic Side Effects Reported to FDA

The following Antineoplastic reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.


The appearance of Antineoplastic on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.
Feeling Cold
This is a report of a 57-year-old male patient (weight: NA) from UNITED STATES, suffering from the following symptoms/conditions: NA, who was treated with Antineoplastic Agents (dosage: NA, start time: Jun 26, 2012), combined with:
  • Leukine (Unk)
and developed a serious reaction and side effect(s). The consumer presented with:
  • Feeling Cold
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Antineoplastic Agents treatment in male patients, resulting in feeling cold side effect.

Injection Site Pruritus
This report suggests a potential Antineoplastic Agents Injection Site Pruritus side effect(s) that can have serious consequences. A 71-year-old male patient (weight: NA) from UNITED STATES was diagnosed with the following symptoms/conditions: NA and used Antineoplastic Agents (dosage: NA) starting NS. Soon after starting Antineoplastic Agents the patient began experiencing various side effects, including:
  • Injection Site Pruritus
Drugs used concurrently:
  • Leukine (250 ?g, Tiw)
Although Antineoplastic Agents demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as injection site pruritus, may still occur.

Pneumonia
This Pneumonia problem was reported by a physician from FRANCE. A 30-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: breast cancer. On NS this consumer started treatment with Antineoplastic Agents (dosage: NA). The following drugs were being taken at the same time:
  • Neulasta
When commencing Antineoplastic Agents, the patient experienced the following unwanted symptoms/side effects:
  • Pneumonia
The patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as pneumonia, may become evident only after a product is in use by the general population.

Interstitial Lung Disease, Respiratory Failure, Dyspnoea, Pyrexia
This is a report of a 71-year-old female patient (weight: NA) from JAPAN. The patient developed the following symptoms/conditions: NA and was treated with Antineoplastic Agents (dosage: NA) starting Dec 28, 2010. Concurrently used drugs:
  • Omeprazole
  • Rebamipide
  • Zometa
  • Maglax
  • Therapeutic Radiopharmaceuticals
  • Vitamin B12
  • Loxoprofen
  • Docetaxel (80 Mg/4 Ml)
Soon after that, the consumer experienced the following side effects:
  • Interstitial Lung Disease
  • Respiratory Failure
  • Dyspnoea
  • Pyrexia
This opens a possibility that Antineoplastic Agents treatment could cause the above reactions, including interstitial lung disease, and some female subjects may be more susceptible.


Hepatitis Toxic, Blood Bilirubin Increased, Jaundice, Abdominal Distension, Chromaturia, Transaminases Increased, Deficiency Of Bile Secretion
A 62-year-old male patient (weight: NA) from SPAIN with the following symptoms/conditions: NA started Antineoplastic Agents treatment (dosage: NA) on May 02, 2012. Soon after starting Antineoplastic Agents treatment, the subject experienced various side effects, including:
  • Hepatitis Toxic
  • Blood Bilirubin Increased
  • Jaundice
  • Abdominal Distension
  • Chromaturia
  • Transaminases Increased
  • Deficiency Of Bile Secretion
Concurrently used drugs:
  • Primovist (Unk)
This finding indicates that some male patients could be more vulnerable to Antineoplastic Agents.

Neoplasm Malignant
A 52-year-old male patient from BRAZIL (weight: NA) experienced symptoms, such as: neoplasm malignant and was treated with Antineoplastic Agents(dosage: NA). The treatment was initiated on Jan 01, 2012. After that a consumer reported the following side effect(s):
  • Neoplasm Malignant
Concurrently used drugs, which potentially could have contributed to side effect(s) or affected Antineoplastic Agents efficacy:
  • Granulokine (Unk)


Myelocytosis
In this report, Antineoplastic Agents was administered for the following condition: acute lymphocytic leukaemia.A 58-year-old female consumer from FRANCE (weight: NA) started Antineoplastic Agents treatment (dosage: NA) on NS.Sometime after starting the treatment, the patient complained of the following side effect(s):
  • Myelocytosis
A possible interaction with other drugs could have contributed to this reaction:
  • Neulasta
Establishing a causal relationship between a specific drug and consumer's side effects is complex, but it is possible that in this report Antineoplastic Agents treatment could be related to the listed above side effect(s).

Abscess
This is a report of the following Antineoplastic Agents side effect(s):
  • Abscess
A 44-year-old female patient from ISRAEL (weight: NA) presented with the following condition: breast cancer,prophylaxis and received a treatment with Antineoplastic Agents (dosage: Unk Unk, Q3wk) starting: NS.The following concurrently used drugs could have generated interactions:
  • Neulastim (Unk Unk, Q3wk)
The patient was hospitalized.This report suggests that a Antineoplastic Agents treatment could be associated with the listed above side effect(s).

Therapeutic Response Decreased, Mantle Cell Lymphoma
This Antineoplastic Agents report was submitted by a 72-year-old female consumer from UNITED STATES (weight: NA). The patient was diagnosed with: mantle cell lymphoma,idiopathic thrombocytopenic purpura and Antineoplastic Agents was administered (dosage: Unk) starting: NS. The consumer developed a set of symptoms:
  • Therapeutic Response Decreased
  • Mantle Cell Lymphoma
Other drugs used simultaneously:
  • Nplate
Those unexpected symptoms could be linked to a Antineoplastic Agents treatment, however establishing a potential drug-safety problem requires a more detailed clinical analysis.

Dyspnoea, Confusional State, Coordination Abnormal, Muscular Weakness
This is a report of a possible correlation between Antineoplastic Agents use and the following symptoms/side effect(s):
  • Dyspnoea
  • Confusional State
  • Coordination Abnormal
  • Muscular Weakness
which could contribute to an assessment of Antineoplastic Agents risk profile.A 68-year-old female consumer from UNITED KINGDOM (weight: NA) was suffering from NA and was treated with Antineoplastic Agents (dosage: NA) starting Feb 16, 2012.Other concurrent medications:
  • Rifampicin
  • Rifampicin
The patient was hospitalized.

Decreased Appetite, Neoplasm Progression, Weight Decreased, Blood Alkaline Phosphatase Increased
A 55-year-old female patient from GERMANY (weight: NA) presented with the following symptoms: NA and after a treatment with Antineoplastic Agents (dosage: Unk) experienced the following side effect(s):
  • Decreased Appetite
  • Neoplasm Progression
  • Weight Decreased
  • Blood Alkaline Phosphatase Increased
The treatment was started on Jan 25, 2012. Antineoplastic Agents was used in combination with the following drugs:
  • Xgeva (120 Mg, Q4wk)
  • Ibuprofen (600 Mg, Tid)
This report could alert potential Antineoplastic Agents consumers.

Febrile Neutropenia, Infection
In this report, a 62-year-old female patient from UNITED STATES (weight: NA) was affected by a possible Antineoplastic Agent (no Ingredients/substances) side effect.The patient was diagnosed with acute lymphocytic leukaemia. After a treatment with Antineoplastic Agent (no Ingredients/substances) (dosage: NA, start date: Dec 01, 2008), the patient experienced the following side effect(s):
  • Febrile Neutropenia
  • Infection
The following simultaneously used drugs could have led to this reaction:
  • Gleevec (600 Mg, Qd, Oral)
The patient was hospitalized.The findings here stress that side effects should be taken into consideration when evaluating a Antineoplastic Agent (no Ingredients/substances) treatment.

Arthralgia, Fractured Sacrum
This is a report of a 52-year-old female patient from UNITED STATES (weight: NA), who used Antineoplastic Agents (dosage: NA) for a treatment of lung neoplasm malignant. After starting a treatment on Mar 09, 2012, the patient experienced the following side effect(s):
  • Arthralgia
  • Fractured Sacrum
The following drugs could possibly have interacted with the Antineoplastic Agents treatment
  • Neulasta (6 Mg, Unk)
Taken together, these observations suggest that a Antineoplastic Agents treatment could be related to side effect(s), such as Arthralgia, Fractured Sacrum.

Syncope, Dysstasia, Dizziness
This syncope side effect was reported by a physician from UNITED STATES. A 76-year-old male patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Antineoplastic Agents (dosage: Unk), which was started on Jan 01, 2011. Concurrently used drugs:
  • Aranesp (300 Mug, Q3wk)
When starting to take Antineoplastic Agents the consumer reported the following symptoms:
  • Syncope
  • Dysstasia
  • Dizziness
These side effects may potentially be related to Antineoplastic Agents.

Confusional State, Muscular Weakness, Coordination Abnormal, Dyspnoea
This is a Antineoplastic Agents side effect report of a 68-year-old female patient (weight:NA) from UNITED KINGDOM, suffering from the following symptoms/conditions: NA, who was treated with Antineoplastic Agents (dosage:NA, start time: Jan 27, 2012), combined with: NA., and developed a serious reaction and a confusional state side effect. The patient presented with:
  • Confusional State
  • Muscular Weakness
  • Coordination Abnormal
  • Dyspnoea
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Antineoplastic Agents treatment in female patients suffering from NA, resulting in confusional state.

Decreased Appetite, Neoplasm Progression, Weight Decreased, Blood Alkaline Phosphatase Increased
This report suggests a potential Antineoplastic Agents decreased appetite side effect(s) that can have serious consequences. A 55-year-old female patient from GERMANY (weight:NA) was diagnosed with the following health condition(s): NA and used Antineoplastic Agents (dosage: NA) starting Jan 25, 2012. Soon after starting Antineoplastic Agents the patient began experiencing various side effects, including:
  • Decreased Appetite
  • Neoplasm Progression
  • Weight Decreased
  • Blood Alkaline Phosphatase Increased
Drugs used concurrently:
  • Xgeva (120 Mg, Q4wk)
  • Ibuprofen (600 Mg, Tid)
Although Antineoplastic Agents demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as decreased appetite, may still occur.

Muscular Weakness, Confusional State, Dyspnoea, Coordination Abnormal, Mycobacterium Tuberculosis Complex Test Positive
This muscular weakness problem was reported by a physician from UNITED KINGDOM. A 68-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Feb 16, 2012 a consumer started treatment with Antineoplastic Agents (dosage: NA). The following drugs/medications were being taken at the same time:
  • Ethambutol Hydrochloride
When commencing Antineoplastic Agents, the patient experienced the following unwanted symptoms /side effects:
  • Muscular Weakness
  • Confusional State
  • Dyspnoea
  • Coordination Abnormal
  • Mycobacterium Tuberculosis Complex Test Positive
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as muscular weakness, may become evident only after a product is in use by the general population.

Coordination Abnormal, Confusional State, Muscular Weakness, Dyspnoea
This is a Antineoplastic Agents side effect report of a 68-year-old female patient (weight: NA) from UNITED KINGDOM. The patient developed the following symptoms/conditions: NA and was treated with Antineoplastic Agents (dosage: NA) starting Jan 27, 2012. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Coordination Abnormal
  • Confusional State
  • Muscular Weakness
  • Dyspnoea
The patient was hospitalized. This opens a possibility that Antineoplastic Agents could cause coordination abnormal and that some female patients may be more susceptible.

Leukocytosis
A 80-year-old female patient (weight: NA) from UNITED STATES with the following symptoms: lung neoplasm malignant,neutropenia started Antineoplastic Agents treatment (dosage: NA) on NS. Soon after starting Antineoplastic Agents treatment, the consumer experienced several side effects, including:
  • Leukocytosis
. Concurrently used drugs:
  • Neulasta (6 Mg, Per Chemo Regim)
This finding indicates that some patients can be more vulnerable to developing Antineoplastic Agents side effects, such as death.

Psychotic Disorder
This psychotic disorder side effect was reported by a pharmacist from NETHERLANDS. A 50-year-old female patient (weight:NA) experienced the following symptoms/conditions: breast cancer,neutropenia.The patient was prescribed Antineoplastic Agents (dosage: NA), which was started on Nov 08, 2011. Concurrently used drugs:
  • Neulasta (6 Mg, Unk)
.When starting to take Antineoplastic Agents the consumer reported symptoms, such as:
  • Psychotic Disorder
These side effects may potentially be related to Antineoplastic Agents.

Malaise
This is a report of a 53-year-old female patient (weight: NA) from UNITED STATES, suffering from the following symptoms/conditions: breast cancer metastatic,metastases to bone, who was treated with Antineoplastic Agents (dosage: Unk, start time: NS), combined with:
  • Xgeva (120 Mg, Unk)
and developed a serious reaction and side effect(s). The consumer presented with:
  • Malaise
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Antineoplastic Agents treatment in female patients, resulting in malaise side effect.

Dehydration, Nausea, Rash, Hyperhidrosis
This report suggests a potential Antineoplastic Agents Dehydration, Nausea, Rash, Hyperhidrosis side effect(s) that can have serious consequences. A 50-year-old female patient (weight: NA) from NETHERLANDS was diagnosed with the following symptoms/conditions: breast cancer and used Antineoplastic Agents (dosage: NA) starting Jan 19, 2012. Soon after starting Antineoplastic Agents the patient began experiencing various side effects, including:
  • Dehydration
  • Nausea
  • Rash
  • Hyperhidrosis
Drugs used concurrently:
  • Neulasta (6 Mg, After Chemo)
The patient was hospitalized. Although Antineoplastic Agents demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as dehydration, may still occur.

Brain Cancer Metastatic
This Brain Cancer Metastatic problem was reported by a health professional from GUATEMALA. A 66-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Antineoplastic Agents (dosage: Form: Vial). The following drugs were being taken at the same time:
  • Lantus
When commencing Antineoplastic Agents, the patient experienced the following unwanted symptoms/side effects:
  • Brain Cancer Metastatic
Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as brain cancer metastatic, may become evident only after a product is in use by the general population.

Confusional State, Muscular Weakness, Coordination Abnormal, Dyspnoea
This is a report of a 68-year-old female patient (weight: NA) from UNITED KINGDOM. The patient developed the following symptoms/conditions: NA and was treated with Antineoplastic Agents (dosage: NA) starting Jan 27, 2012. Concurrently used drugs:
  • Rifampicin
Soon after that, the consumer experienced the following side effects:
  • Confusional State
  • Muscular Weakness
  • Coordination Abnormal
  • Dyspnoea
The patient was hospitalized. This opens a possibility that Antineoplastic Agents treatment could cause the above reactions, including confusional state, and some female subjects may be more susceptible.

Chills, Hypokalaemia, Tubulointerstitial Nephritis, Depressed Level Of Consciousness, White Blood Cell Count Increased, Blood Cortisol Decreased, Leukocyturia, Hypopituitarism, Renal Impairment
A female patient (weight: NA) from JAPAN with the following symptoms/conditions: NA started Antineoplastic Agents treatment (dosage: NA) on Dec 01, 2009. Soon after starting Antineoplastic Agents treatment, the subject experienced various side effects, including:
  • Chills
  • Hypokalaemia
  • Tubulointerstitial Nephritis
  • Depressed Level Of Consciousness
  • White Blood Cell Count Increased
  • Blood Cortisol Decreased
  • Leukocyturia
  • Hypopituitarism
  • Renal Impairment
Concurrently used drugs:
  • Vitamin D (Unk Ukn, Unk)
  • Ts 1 (60 Mg, Unk)
  • Zometa (4 Mg, Qmo)
  • Vitamin D
  • Spiriva
  • Medroxyprogesterone Acetate (400 Mg, Unk)
This finding indicates that some female patients could be more vulnerable to Antineoplastic Agents.

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Keep Track of Side Effects

Note Your Observations

It is really important to keep of your symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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    More About Antineoplastic

    Side Effects reported to FDA: 73

    Antineoplastic safety alerts: No

    Reported deaths: 21

    Reported hospitalizations: 32

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