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Penis Weak (30)
Weight Gain (26)
Breathlessness (17)
Irritated Muscels (13)
Memory Loosing (10)
Hand Cramps (8)
Drowsiness (7)
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Aprovel Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 397 

Neutropenia, Acute Leukaemia, Pseudomonas Infection, Encephalopathy, Urinary Tract Infection, Coma, Heparin-induced Thrombocytopenia, Quadriplegia (7423101-2)
on Apr 11, 2011 Female from FRANCE , 65 years of age, was treated with Aprovel. Directly after, patient experienced the unwanted or unexpected Aprovel side effects: neutropenia, acute leukaemia, pseudomonas infection, encephalopathy, urinary tract infection, coma, heparin-induced thrombocytopenia, quadriplegia. Aprovel dosage: N/A.
Associated medications used:
  • Ranitidine
  • Levothyrox
  • Neorecormon
  • Eprex
  • Neupogen (Unk)
  • Fluorouracil
  • Folic Acid
  • Cisplatin
Patient was hospitalized.

Dysgeusia, Weight Decreased (7411826-4)
Patient was taking Aprovel. Patient felt the following Aprovel side effects: dysgeusia, weight decreased on Apr 04, 2011 from FRANCE Additional patient health information: Female , 72 years of age, was diagnosed with
  • hypertension
and. Aprovel dosage: 1 Anz.
Multiple prescriptions taken:
  • Crestor
  • Triatec (1 Anz)
  • Telmisartan (1 Anz)
  • Kardegic
  • Uncodeable ^unclassifiable^
  • Cardensiel
Patient was hospitalized.

Renal Failure Chronic (7408705-5)
Adverse event was reported on Apr 05, 2011 by a Male taking Aprovel Tabs 150 Mg (Dosage: N/A) was diagnosed with
  • hypertension
and. Location: MEXICO , 61 years of age, After Aprovel was administered, patient encountered several Aprovel side effects: renal failure chronic.

Pulmonary Arterial Hypertension, Dyspnoea Exertional (7397621-3)
on Apr 01, 2011 Male from FRANCE , 66 years of age, was treated with Aprovel Tabs 150 Mg. Directly after, patient experienced the unwanted or unexpected Aprovel side effects: pulmonary arterial hypertension, dyspnoea exertional. Aprovel Tabs 150 Mg dosage: N/A.
Associated medications used:
  • Foradil
  • Miflasone
  • Pravastatin Sodium
  • Plavix
  • Eucreas (Eucreas 50mg/1000mg)
  • Spiriva
  • Diamox
  • Mediator



Pancreatitis Acute (7357609-5)
on Mar 08, 2011 Male from FRANCE , 54 years of age, was diagnosed with
  • hypertension
and was treated with Aprovel. Patient felt the following Aprovel side effects: pancreatitis acute. Aprovel dosage: N/A.

Bladder Transitional Cell Carcinoma Stage 0 (7346193-8)
Patient was taking Aprovel (irbesartan). After Aprovel was administered, patient encountered several Aprovel side effects: bladder transitional cell carcinoma stage 0 on Feb 10, 2011 from TUNISIA Additional patient health information: Male , 65 years of age, . Aprovel (irbesartan) dosage: N/A.
Multiple concurrent drugs taken:
  • Amaryl
  • Glucophage
  • Amlodipine Besylate
  • Actos (30 Mg, Per Oral)
Patient was hospitalized.

Renal Failure Chronic (7344503-9)
Adverse event was reported on Mar 03, 2011 by a Male taking Aprovel Tabs 150 Mg (Dosage: N/A) was diagnosed with
  • hypertension
  • gastritis
and. Location: MEXICO , 71 years of age, Directly after, patient experienced the unwanted or unexpected Aprovel side effects: renal failure chronic.
Associated medications used:
  • Omeprazole (Tabs)


Subileus (7334927-8)
on Feb 25, 2011 Female from GERMANY , weighting 130.1 lb, was treated with Aprovel. Patient felt the following Aprovel side effects: subileus. Aprovel dosage: Reported As: Aprovel 300, Daily Dose: 1x.
Multiple prescriptions taken:
  • Coaprovel
  • Metoprolol (Reported As: Metoprolol 35, Daily Dose: 1x)
  • Spiriva
  • Capecitabine (Route And Dose: As Per Protocol, Date Of Last Dose Prior To Sae: 19 Feb 2011)
  • Bevacizumab (On Day 1, Route And Dose: As Per Protocol, Date Of Last Dose Prior To Sae: 15 Feb 2011)
  • Torem
  • Levothyroxine Sodium
  • Insulin
Patient was hospitalized.

Pancreatic Fistula, Abdominal Wound Dehiscence, Pancreatitis Necrotising, Pyelonephritis (7302178-9)
on Feb 14, 2011 Male from FRANCE , 41 years of age, weighting 213.8 lb, was treated with Aprovel. After Aprovel was administered, patient encountered several Aprovel side effects: pancreatic fistula, abdominal wound dehiscence, pancreatitis necrotising, pyelonephritis. Aprovel dosage: N/A.
Multiple concurrent drugs taken:
  • Tahor (40 Mg, Unk)
  • Cardensiel
  • Aspirin
Patient was hospitalized and became disabled.

Myocardial Infarction, Chest Pain (7288464-X)
Patient was taking Aprovel. Directly after, patient experienced the unwanted or unexpected Aprovel side effects: myocardial infarction, chest pain on Feb 02, 2011 from FRANCE Additional patient health information: Male , 55 years of age, weighting 220.5 lb, . Aprovel dosage: N/A.
Associated medications used:
  • Avandamet
Patient was hospitalized.

Haematocrit Decreased, Myocardial Infarction (7272909-5)
Adverse event was reported on Jan 24, 2011 by a Male taking Aprovel (Dosage: N/A) was diagnosed with
  • hypertension
and. Location: GREECE , 82 years of age, Patient felt the following Aprovel side effects: haematocrit decreased, myocardial infarction.
Multiple prescriptions taken:
  • Salospir
  • Clexane
  • Plavix
  • Seropram
  • Glucophage
Patient was hospitalized.

Renal Failure Chronic, Sinoatrial Block (7238140-4)
on Jan 10, 2011 Male from SPAIN , 64 years of age, was diagnosed with
  • hypertension
  • myocardial ischaemia
  • arrhythmia
and was treated with Aprovel. After Aprovel was administered, patient encountered several Aprovel side effects: renal failure chronic, sinoatrial block. Aprovel dosage: N/A.
Multiple concurrent drugs taken:
  • Ranolazine
  • Atenolol
  • Multaq
  • Crestor
  • Sintrom
Patient was hospitalized.

Angioedema (7236039-0)
on Jan 17, 2011 Male from FRANCE , 37 years of age, was treated with Aprovel. Directly after, patient experienced the unwanted or unexpected Aprovel side effects: angioedema. Aprovel dosage: N/A.

Atrioventricular Block First Degree, Rales, Bundle Branch Block Left, Blood Pressure Immeasurable, Aggression, Cognitive Disorder, Bundle Branch Block Right, Agitation, Somnolence (7226692-X)
Patient was taking Aprovel Tabs 150 Mg. Patient felt the following Aprovel side effects: atrioventricular block first degree, rales, bundle branch block left, blood pressure immeasurable, aggression, cognitive disorder, bundle branch block right, agitation, somnolence on Jan 10, 2011 from FRANCE Additional patient health information: Male , 86 years of age, . Aprovel Tabs 150 Mg dosage: Tabs.
Multiple prescriptions taken:
  • Efferalgan
  • Glyburide
  • Lantus (1df=4units. In Evening)
  • Glucor
  • Aspirin
  • Nitroglycerin
Patient was hospitalized.

Hepatic Failure (7224337-6)
Adverse event was reported on Jan 10, 2011 by a Male taking Aprovel Tabs 150 Mg (Dosage: Tab) . Location: FRANCE , 79 years of age, After Aprovel was administered, patient encountered several Aprovel side effects: hepatic failure.
Multiple concurrent drugs taken:
  • Stagid (Stagid 700 Mg Tablet)
  • Allopurinol
  • Furadantine (Furadantine 50 Mg Caps Dec09:apr10: 50 Mg Every Other Day. 12jun2010:5jul2010:50mg 3/d.)
  • Kardegic (Kardegic 75 Mg Sachet)
  • Tenormin (1df:0.5 Unit Nos Tenormine 50 Mg Tablet)
Patient was hospitalized.

Viith Nerve Paralysis, Chills, Pyrexia, Pain, Eyelid Disorder (7221273-6)
on Jan 03, 2011 Female from FRANCE , 68 years of age, was diagnosed with
  • hypertension
and was treated with Aprovel. Directly after, patient experienced the unwanted or unexpected Aprovel side effects: viith nerve paralysis, chills, pyrexia, pain, eyelid disorder. Aprovel dosage: N/A.
Associated medications used:
  • Cacit
  • Foradil
  • Ismelin (Unk)
  • Moroxydine
  • Flixotide
  • Vitamin D3
  • Aclasta


Respiratory Depression, Coma (7220603-9)
on Jan 04, 2011 Female from SWITZERLAND , 89 years of age, was treated with Aprovel. Patient felt the following Aprovel side effects: respiratory depression, coma. Aprovel dosage: 300 Mg, 1x/day.
Multiple prescriptions taken:
  • Dafalgan (1 G, 3x/day)
  • Nexium (40 Mg, 1x/day)
  • Paspertin (10 Mg, 3x/day)
  • Neurontin (300 Mg, 3x/day)
  • Amlodipine (5 Mg, 1x/day)
  • Torem (10 Mg, 1x/day)
  • Movicol (2 Df, 1x/day)
  • Dormicum For Injection (3 Mg, Single)


Cardio-respiratory Arrest, Shock, Neutropenia, Aspiration (7213783-2)
Patient was taking Aprovel. After Aprovel was administered, patient encountered several Aprovel side effects: cardio-respiratory arrest, shock, neutropenia, aspiration on Jan 05, 2011 from FRANCE Additional patient health information: Male , weighting 163.1 lb, was diagnosed with
  • hypertension
  • helicobacter infection
and. Aprovel dosage: 150 Mg Daily.
Multiple concurrent drugs taken:
  • Nexium
  • Clarithromycin (1 Gram Daily)
  • Lodales
  • Colchicine (3 Mg Daily)
  • Colchicine (29 Apr2010 2 Tablet/day Then 1tablet/day)
  • Isoptin
  • Noroxin
  • Acetaminophen
Patient was hospitalized.

Abnormal Behaviour, Cardiac Failure, Fall, Hypercreatininaemia, Hyponatraemia, Joint Dislocation (7202217-X)
Adverse event was reported on Dec 22, 2010 by a Female taking Aprovel (Dosage: N/A) . Location: FRANCE , 86 years of age, Directly after, patient experienced the unwanted or unexpected Aprovel side effects: abnormal behaviour, cardiac failure, fall, hypercreatininaemia, hyponatraemia, joint dislocation.
Associated medications used:
  • Lasix
  • Seresta (1 Df=0.5/day Of 10 Mg)
  • Risperdal (1 Df=half Of A 1 Mg Tablet)
  • Rivotril
  • Kardegic
  • Hemigoxine Nativelle
Patient was hospitalized.

Toxic Skin Eruption (7190147-1)
on Dec 20, 2010 Male from FRANCE , 64 years of age, was diagnosed with
  • hypertension
and was treated with Aprovel Tabs. Patient felt the following Aprovel side effects: toxic skin eruption. Aprovel Tabs dosage: 150mg 2jul10-16jul10:duration 2 Week,discon On 25sep2010.dose Increased To 300mg 17jul-01oct10.
Multiple prescriptions taken:
  • Coversyl
Patient was hospitalized.

Renal Failure Acute (7176845-4)
on Dec 09, 2010 Female from MALAYSIA , 50 years of age, was treated with Aprovel. After Aprovel was administered, patient encountered several Aprovel side effects: renal failure acute. Aprovel dosage: N/A.
Multiple concurrent drugs taken:
  • Diltiazem Hcl


Blood Glucose Increased (7134032-X)
Patient was taking Aprovel. Directly after, patient experienced the unwanted or unexpected Aprovel side effects: blood glucose increased on Sep 24, 2010 from GREECE Additional patient health information: Male , 78 years of age, was diagnosed with
  • hypertension
  • diabetes mellitus
and. Aprovel dosage: N/A.
Associated medications used:
  • Glucophage
  • Lopressor


Cholestasis, Coma Acidotic, Cytolytic Hepatitis, Lactic Acidosis, Renal Failure Acute (7132256-9)
Adverse event was reported on Nov 25, 2010 by a Male taking Aprovel Tabs 300 Mg (Dosage: N/A) was diagnosed with
  • hypertension
  • type 2 diabetes mellitus
  • h1n1 influenza
  • arthralgia
and. Location: FRANCE , 40 years of age, Patient felt the following Aprovel side effects: cholestasis, coma acidotic, cytolytic hepatitis, lactic acidosis, renal failure acute.
Multiple prescriptions taken:
  • Competact (1df=15mg/850mg)
  • Pandemrix
  • Bi-profenid
  • Celebrex
  • Pravigard Pac (copackaged)
  • Solian
  • Xatral
  • Akineton
Patient was hospitalized.

(7131248-3)
on Nov 25, 2010 Female from MEXICO , 93 years of age, was diagnosed with
  • hypertension
and was treated with Aprovel Tabs 150 Mg. . Aprovel Tabs 150 Mg dosage: N/A.

Hypertension, Metabolic Disorder, Renal Failure Chronic, Type 2 Diabetes Mellitus (7124779-3)
on Nov 22, 2010 Female from MEXICO , 80 years of age, was diagnosed with
  • hypertension
and was treated with Aprovel Tabs 150 Mg. Directly after, patient experienced the unwanted or unexpected Aprovel side effects: hypertension, metabolic disorder, renal failure chronic, type 2 diabetes mellitus. Aprovel Tabs 150 Mg dosage: N/A.

Showing 1-25 of 397 

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Aprovel Information

More About Aprovel

Side Effects reported to FDA: 397. View Aprovel Adverse Reports

Aprovel safety alerts: No

Reported deaths: 17

Reported hospitalizations: 71

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