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Aptivus Safety Reports
Total Aptivus reports: 133.Aptivus FDA safety alerts: 2006 .
Reported deaths: 20 Reported hospitalizations: 67.
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Reported Aptivus Side Effects: haemorrhage intracranial, diarrhoea, gastrointestinal disorder, convulsion, mental status changes, cerebrovascular accident, death, cerebral haemorrhage, jaundice, headache, liver function test abnormal.
Aptivus Usage.
Showing 1-50 of 133 Next >
Aptivus Side Effects Report #5319476-0Health Professional from AUSTRALIA reported APTIVUS problem on May 05, 2007. Male patient, weighting 103.6 lb, was diagnosed with hiv infection, prophylaxis, gastrooesophageal reflux disease, medical diet, neuralgia, chronic obstructive pulmonary disease and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: end stage aids, enterococcal infection, infective exacerbation of chronic obstructive airways disease, lung neoplasm. APTIVUS dosage: TPV/RTV 1000/400 MG. During the same period patient was treated with TRUVADA, VIRAMUNE, BACTRIM, PANTOPRAZOLE, FOLIC ACID, METHADONE, SPIRIVA. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5326704-4
APTIVUS problem was reported by a Health Professional from UNITED STATES on May 10, 2007. Female patient, 74 years of age, weighting 132.3 lb, was diagnosed with hiv infection, acquired immunodeficiency syndrome and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: abasia, anorexia, asthenia, dehydration, dysphagia, eaton-lambert syndrome, eyelid disorder, eyelid ptosis, fatigue. APTIVUS dosage: TPV/RTV 500MG/200MG BID. During the same period patient was treated with FUZEON, VIREAD, ZERIT, VIDEX, PROCARDIA, LASIX. Patient was hospitalized and became disabled. Patient recovered.
Aptivus Side Effects Report #5326713-5
Health Professional from AUSTRALIA reported APTIVUS problem on May 04, 2007. Male patient, weighting 151.0 lb, was diagnosed with hiv infection, blood testosterone decreased, herpes simplex, reflux oesophagitis, antifungal prophylaxis, agoraphobia and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: subcutaneous abscess. APTIVUS dosage: TPV/RTV 1000/400 MG. During the same period patient was treated with SUSTANON, VALTREX, VENTOLIN, ACIMAX, BACTRIM DS, TRUVADA, OXAPAM. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5327925-7
APTIVUS problem was reported by a Physician from FRANCE on May 14, 2007. Male patient, 48 years of age, weighting 121.3 lb, was diagnosed with hiv infection and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: coagulation factor decreased, haemarthrosis. APTIVUS dosage: unknown. During the same period patient was treated with VIREAD, KIVEXA. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5327926-9
Physician from reported APTIVUS problem on Dec 12, 2006. Female patient, weighting 105.8 lb, was diagnosed with acquired immunodeficiency syndrome and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: coma hepatic, hepatic function abnormal. APTIVUS dosage: unknown. During the same period patient was treated with RITONAVIR, TRUVADA. Patient died on 07/25/2006.
Aptivus Side Effects Report #5330389-0
APTIVUS problem was reported by a Health Professional from AUSTRALIA on May 05, 2007. Male patient, weighting 103.6 lb, was diagnosed with hiv infection, prophylaxis, gastrooesophageal reflux disease, medical diet, neuralgia, chronic obstructive pulmonary disease and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: end stage aids, enterococcal infection, infective exacerbation of chronic obstructive airways disease, lung neoplasm. APTIVUS dosage: TPV/RTV 1000/400 MG. During the same period patient was treated with TRUVADA, VIRAMUNE, BACTRIM, PANTOPRAZOLE, FOLIC ACID, METHADONE, SPIRIVA. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5331523-9
Physician from FRANCE reported APTIVUS problem on May 14, 2007. Male patient, 48 years of age, weighting 121.3 lb, was diagnosed with hiv infection and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: coagulation factor decreased, haemarthrosis. APTIVUS dosage: TPV/RTV COADM. RTV: 400 MG. During the same period patient was treated with VIREAD, KIVEXA. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5349857-0
APTIVUS problem was reported by a Consumer or non-health professional from on May 29, 2007. Male patient, weighting 158.7 lb, was diagnosed with hiv infection and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: cytolytic hepatitis. APTIVUS dosage: unknown. During the same period patient was treated with NORVIR, VIDEX, ZIAGEN, BISEPTOL, ESSENTIALETE. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5360955-8
Physician from FRANCE reported APTIVUS problem on June 11, 2007. Male patient, 48 years of age, weighting 121.3 lb, was diagnosed with hiv infection and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: cardiac tamponade, coagulation factor decreased, haemarthrosis, pericardial haemorrhage. APTIVUS dosage: TPV/RTV COADM. RTV: 400 MG. During the same period patient was treated with VIREAD, KIVEXA. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5043473-6
APTIVUS problem was reported by a Physician from UNITED STATES on June 06, 2006. Male patient, weighting 100.2 lb, was diagnosed with hiv infection and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: deafness, meningitis cryptococcal. APTIVUS dosage: TPV 1000MG/RTV ?. During the same period patient was treated with FUZEON, COMBIVIR. Patient died on 01/23/2006.
Aptivus Side Effects Report #5044695-0
Physician from FRANCE reported APTIVUS problem on Apr 13, 2006. Male patient, weighting 165.3 lb, was diagnosed with hiv infection and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: convulsion. APTIVUS dosage: TPV/RTV: 500/100 MG B.I.D.. During the same period patient was treated with DEPAKENE, FUZEON, WELLVONE. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5048329-0
APTIVUS problem was reported by a Physician from UNITED STATES on June 06, 2006. Male patient, 47 years of age, weighting 141.0 lb, was diagnosed with hiv infection, acquired immunodeficiency syndrome and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: refusal of treatment by patient. APTIVUS dosage: TPV 1000MG / RTV ?. During the same period patient was treated with CLINDAMYCIN, DARAPRIM, DAPSONE, SPORANOX, ZITHROMAX, LEUCOVORIN CALCIUM, TRUVADA. Patient died on 09/15/2005.
Aptivus Side Effects Report #5051881-2
Physician from UNITED STATES reported APTIVUS problem on June 06, 2006. Male patient, 47 years of age, weighting 141.0 lb, was diagnosed with hiv infection, acquired immunodeficiency syndrome and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: oral intake reduced, refusal of treatment by patient, treatment noncompliance. APTIVUS dosage: TPV 1000MG / RTV ?. During the same period patient was treated with CLINDAMYCIN, DARAPRIM, DAPSONE, SPORANOX, ZITHROMAX, LEUCOVORIN CALCIUM, TRUVADA. Patient died on 09/15/2005.
Aptivus Side Effects Report #5053085-6
APTIVUS problem was reported by a Physician from UNITED STATES on June 06, 2006. Male patient, 47 years of age, weighting 141.0 lb, was diagnosed with hiv infection, acquired immunodeficiency syndrome and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: encephalopathy, toxoplasmosis. APTIVUS dosage: TPV 1000MG / RTV ?. During the same period patient was treated with CLINDAMYCIN, DARAPRIM, DAPSONE, SPORANOX, ZITHROMAX, LEUCOVORIN CALCIUM, TRUVADA. Patient died on 09/15/2005.
Aptivus Side Effects Report #5056554-8
Consumer or non-health professional from reported APTIVUS problem on July 12, 2006. Male patient, weighting 147.7 lb, was diagnosed with hiv infection and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: lymphoma. APTIVUS dosage: TIPRANAVIR 1000 MG + RITONAVIR 400 MG. During the same period patient was treated with VIREAD, ZIAGEN, FUZEON. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5061402-6
APTIVUS problem was reported by a Physician from on June 19, 2006. Male patient, weighting 163.1 lb, was diagnosed with hiv infection, hypertension, diabetes mellitus and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: blood triglycerides increased, carotid artery stenosis, cerebrovascular accident, monoparesis, reversible ischaemic neurological deficit. APTIVUS dosage: TIPRANAVIR 1000 MG/NORVIR 100 MG (RITONAVIR). During the same period patient was treated with TRIZIVIR, NORVASC, CAPTOHEXAL, GLUCOPHAGE. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5061414-2
Consumer or non-health professional from UNITED STATES reported APTIVUS problem on July 06, 2006. Male patient, 53 years of age, weighting 163.4 lb, was diagnosed with hiv infection, acquired immunodeficiency syndrome and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: cerebrovascular accident, haemorrhage intracranial, hypertension. APTIVUS dosage: TPV/ RTV 1000/ ? MG. During the same period patient was treated with MARAVIROX, EPIVIR, FUZEON, PREVACID, ZITHROMAX, AMITRIPTYLINE, SEROSTIM. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5063933-1
APTIVUS problem was reported by a Consumer or non-health professional from on July 12, 2006. Male patient, weighting 130.1 lb, was diagnosed with hiv infection and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: varices oesophageal. APTIVUS dosage: TIPRANAVIR 1000 MG + RITONAVIR 400 MG. During the same period patient was treated with VIDEX, ZERIT, VIREAD. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5064968-5
Consumer or non-health professional from UNITED STATES reported APTIVUS problem on July 06, 2006. Male patient, 53 years of age, weighting 163.4 lb, was diagnosed with hiv infection, acquired immunodeficiency syndrome and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: cerebrovascular accident, haemorrhage intracranial, hypertension. APTIVUS dosage: TPV/ RTV 1000/ 400 MG. During the same period patient was treated with MARAVIROX, EPIVIR, FUZEON, PREVACID, ZITHROMAX, AMITRIPTYLINE, SEROSTIM. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5064969-7
APTIVUS problem was reported by a Physician from on June 19, 2006. Male patient, weighting 163.1 lb, was diagnosed with hiv infection, hypertension, diabetes mellitus and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: blood triglycerides increased, carotid artery stenosis, cerebrovascular accident, monoparesis, reversible ischaemic neurological deficit. APTIVUS dosage: TIPRANAVIR 1000 MG/NORVIR 100 MG (RITONAVIR). During the same period patient was treated with TRIZIVIR, NORVASC, CAPTOHEXAL, GLUCOPHAGE. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5078162-5
Pharmacist from UNITED STATES reported APTIVUS problem on Mar 28, 2006. Female patient was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: jaundice, liver function test abnormal, pancreatitis. APTIVUS dosage: unknown. Patient recovered.
Aptivus Side Effects Report #5078164-9
APTIVUS problem was reported by a Physician from UNITED STATES on Apr 11, 2006. Female patient was diagnosed with urticaria and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: renal impairment. APTIVUS dosage: 1000 MG (250 MG, 500 MG BID), PO. During the same period patient was treated with FUZEON, EPZICOM, NORVIR, VIDEX EC, VIREAD, KALETRA. Patient recovered.
Aptivus Side Effects Report #5078167-4
Physician from UNITED STATES reported APTIVUS problem on May 16, 2006. Female patient was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: platelet count decreased. APTIVUS dosage: unknown. During the same period patient was treated with BACTRIM, ZIAGIN, EIVIR. Patient recovered.
Aptivus Side Effects Report #5078171-6
APTIVUS problem was reported by a Physician from UNITED STATES on Apr 11, 2006. Female patient was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: blood triglycerides increased, viral load. APTIVUS dosage: (SEE TEXT,250 MG TIPRANAVIR / 100MG RITONAVIR). During the same period patient was treated with SUSTIVA, TRUVADA, FUZEON. Patient recovered.
Aptivus Side Effects Report #5078181-9
Physician from UNITED STATES reported APTIVUS problem on Apr 11, 2006. Male patient, 36 years of age, was diagnosed with acquired immunodeficiency syndrome and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: cd4 lymphocytes decreased, injection site nodule, viral load increased. APTIVUS dosage: unknown. During the same period patient was treated with TENOFOVIR. Patient recovered.
Aptivus Side Effects Report #5078182-0
APTIVUS problem was reported by a Consumer or non-health professional from UNITED STATES on May 23, 2006. Female patient was diagnosed with hiv infection and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: low density lipoprotein increased. APTIVUS dosage: (SEE TEXT, TPV/RTV 250/100MG), PO. Patient recovered.
Aptivus Side Effects Report #5078184-4
Consumer or non-health professional from UNITED STATES reported APTIVUS problem on June 06, 2006. Female patient was diagnosed with urticaria and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: lip discolouration. APTIVUS dosage: (SEE TEXT, TPV/RTV 250MG/100MG), PO. During the same period patient was treated with FUZEON. Patient recovered.
Aptivus Side Effects Report #5078185-6
APTIVUS problem was reported by a Health Professional from UNITED STATES on Mar 29, 2006. Female patient, 41 years of age, weighting 252.4 lb, was diagnosed with hiv infection and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: pruritus. APTIVUS dosage: SEE TEXT (SEE TEXT, STRENGTH: 250MG/100MG DOSE: 2 CAPSULES BID), PO. During the same period patient was treated with EPZICOM, VIREAD, FUZEON. Patient recovered.
Aptivus Side Effects Report #5078192-3
Physician from UNITED STATES reported APTIVUS problem on Mar 27, 2006. Female patient was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: rash. APTIVUS dosage: unknown. Patient recovered.
Aptivus Side Effects Report #5068983-7
APTIVUS problem was reported by a Consumer or non-health professional from on July 12, 2006. Male patient, weighting 147.7 lb, was diagnosed with hiv infection and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: lymphoma. APTIVUS dosage: TIPRANAVIR 1000 MG + RITONAVIR 400 MG. During the same period patient was treated with VIREAD, ZIAGEN, FUZEON. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5070179-X
Consumer or non-health professional from reported APTIVUS problem on July 12, 2006. Male patient, weighting 130.1 lb, was diagnosed with hiv infection and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: varices oesophageal. APTIVUS dosage: TIPRANAVIR 1000 MG + RITONAVIR 400 MG. During the same period patient was treated with VIDEX, ZERIT, VIREAD. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5074457-X
APTIVUS problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 27, 2006. Male patient, weighting 119.2 lb, was diagnosed with hiv infection, convulsion and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: cardiac arrest, convulsion, cytomegalovirus infection, hiv infection, loss of consciousness. APTIVUS dosage: TPV/R 1000/400 MG. During the same period patient was treated with DEPAKOTE, TOPAMAX. Patient died on 03/24/2006.
Aptivus Side Effects Report #5074458-1
Consumer or non-health professional from UNITED STATES reported APTIVUS problem on July 06, 2006. Male patient, 53 years of age, weighting 163.4 lb, was diagnosed with hiv infection, acquired immunodeficiency syndrome and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: cerebrovascular accident, haemorrhage intracranial, hypertension. APTIVUS dosage: TPV/ RTV 1000/ 400 MG. During the same period patient was treated with MARAVIROX, EPIVIR, FUZEON, PREVACID, ZITHROMAX, AMITRIPTYLINE, SEROSTIM. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5079619-3
APTIVUS problem was reported by a Physician from on Aug 03, 2006. Male patient, 49 years of age, weighting 110.2 lb, was diagnosed with hiv infection and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: ascites, calcinosis, hepatosplenomegaly, jaundice. APTIVUS dosage: TPV/RTV: 500/200 MG B.I.D.. During the same period patient was treated with TRUVADA, NATULAN, SOLUPRED, OXYCONTIN. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5082884-X
Physician from UNITED STATES reported APTIVUS problem on July 26, 2006. Male patient, 46 years of age, was diagnosed with hiv infection and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: kaposi's sarcoma, pulmonary embolism. APTIVUS dosage: DOSE: 1000 MG/400MG. During the same period patient was treated with TRUVADA, SULFADIAZINE, LEUCOVORIN CALCIUM, AZITHROMYCIN, MEGACE, ACYCLOVIR, DIFLUCAN. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5084041-X
APTIVUS problem was reported by a Consumer or non-health professional from on May 26, 2006. Male patient was diagnosed with hiv infection, chronic obstructive pulmonary disease and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: cushing's syndrome, subcutaneous abscess, urinary tract infection. APTIVUS dosage: TIPRANAVIR 1000 MG + RITONAVIR 400MG. During the same period patient was treated with RILAST, FUZEON, TENOFOVIR, SERETIDE. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5084920-3
Physician from UNITED STATES reported APTIVUS problem on Aug 17, 2006. Male patient, 37 years of age, was diagnosed with hiv infection and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: blood pressure increased, haemorrhage intracranial, malaise, mental status changes. APTIVUS dosage: unknown. During the same period patient was treated with MEGACE, PRAVACHOL, DARAPRIM, BUSPAR, KEPPRA, SEREVENT, CHOLESTYRAMINE, CELEXA. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5095581-1
APTIVUS problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 27, 2006. Male patient, weighting 119.2 lb, was diagnosed with hiv infection, convulsion and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: cardiac arrest, cardiac disorder, convulsion, cytomegalovirus oesophagitis, loss of consciousness, nervous system disorder. APTIVUS dosage: TPV/R 1000/400 MG. During the same period patient was treated with DEPAKOTE, TOPAMAX, DURAGESIC, VALCYTE, AMBIEN, PEPCID, TRIMETHOPRIM. Patient died on 03/24/2006.
Aptivus Side Effects Report #5095604-X
Physician from UNITED STATES reported APTIVUS problem on Aug 17, 2006. Male patient, 37 years of age, weighting 150.4 lb, was diagnosed with hiv infection and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: blood pressure increased, cerebral haemorrhage, haemorrhage intracranial, hydrocephalus, malaise, mental status changes, platelet count decreased, white blood cell count decreased. APTIVUS dosage: TPV/ RTV 1000/400 MG. During the same period patient was treated with MEGACE, PRAVACHOL, DARAPRIM, BUSPAR, KEPPRA, SEREVENT, CHOLESTYRAMINE. Patient was hospitalized and became disabled. Patient recovered.
Aptivus Side Effects Report #5098307-0
APTIVUS problem was reported by a Physician from UNITED STATES on Aug 17, 2006. Male patient, 37 years of age, weighting 150.4 lb, was diagnosed with hiv infection and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: blood pressure increased, haemorrhage intracranial, hydrocephalus, mental status changes, platelet count decreased, white blood cell count decreased. APTIVUS dosage: TPV/ RTV 1000/400 MG. During the same period patient was treated with MEGACE, PRAVACHOL, DARAPRIM, BUSPAR, KEPPRA, SEREVENT, CHOLESTYRAMINE. Patient was hospitalized and became disabled. Patient recovered.
Aptivus Side Effects Report #5105049-1
Physician from UNITED STATES reported APTIVUS problem on Sept 11, 2006. Male patient, 51 years of age, was diagnosed with hiv infection and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: blood amylase increased, constipation, depressed level of consciousness, hepatic failure, renal failure acute, unresponsive to stimuli. APTIVUS dosage: unknown. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5113056-8
APTIVUS problem was reported by a Physician from FRANCE on Apr 13, 2006. Male patient, 47 years of age, weighting 165.3 lb, was diagnosed with hiv infection, epilepsy and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: convulsion. APTIVUS dosage: TPV/RTV: 500/100 MG B.I.D.. During the same period patient was treated with DEPAKENE, FUZEON, WELLVONE. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5113057-X
Physician from UNITED STATES reported APTIVUS problem on June 06, 2006. Male patient, 44 years of age, was diagnosed with hiv infection and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: anaemia, cachexia, diarrhoea, haematochezia, metastases to lung, oesophageal adenocarcinoma stage iv, upper gastrointestinal haemorrhage. APTIVUS dosage: TPV/RTV 1000/200 MG. During the same period patient was treated with DEMEROL, PROTONIX, BACTRIM, KLONOPIN, AMBIEN, FUZEON, EPZICOM, DIFLUCAN. Patient was hospitalized and became disabled. Patient died on 10/22/2005.
Aptivus Side Effects Report #5116304-3
APTIVUS problem was reported by a Physician from UNITED STATES on Sept 25, 2006. Male patient was diagnosed with hiv infection and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: haemoptysis. APTIVUS dosage: DAILY DOSE: 500/200 MG BID. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5120694-5
Physician from UNITED STATES reported APTIVUS problem on Sept 11, 2006. Male patient, 51 years of age, weighting 119.0 lb, was diagnosed with hiv infection and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: blood amylase increased, constipation, hepatic failure, renal failure acute, unresponsive to stimuli. APTIVUS dosage: unknown. During the same period patient was treated with LIPITOR, GEMFIBROZIL, AMBIEN, PAMELOR, LORATADINE, MANGOSTEIN NUTRITIONAL SUPPLEMENT, PROTONIX, ATIVAN. Patient was hospitalized. Patient recovered.
Aptivus Side Effects Report #5121250-5
APTIVUS problem was reported by a Physician from FRANCE on Sept 28, 2006. Male patient, 53 years of age, weighting 160.9 lb, was diagnosed with hiv infection, coagulopathy and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: haemarthrosis, haemorrhage. APTIVUS dosage: TPV/RTV: 1000 MG / 400 MG DAILY. During the same period patient was treated with ZIAGEN, TRUVADA, KOGENATE. Patient recovered.
Aptivus Side Effects Report #5133170-0
Consumer or non-health professional from reported APTIVUS problem on June 14, 2006. Male patient, weighting 169.8 lb, was diagnosed with hiv infection and was treated with APTIVUS. APTIVUS dosage: TIPRANAVIR 1000 MG + RITONAVIR 400 MG. During the same period patient was treated with FUZEON. Patient died on 04/01/2006.
Aptivus Side Effects Report #5206280-7
APTIVUS problem was reported by a Health Professional from UNITED STATES on Aug 07, 2006. Male patient was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: lipodystrophy acquired. APTIVUS dosage: unknown. Patient recovered.
Aptivus Side Effects Report #5206281-9
Consumer or non-health professional from UNITED STATES reported APTIVUS problem on Aug 28, 2006. Male patient was diagnosed with hiv infection and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased. APTIVUS dosage: SEE TEXT, 250 MG/100 MG, PO. Patient recovered.
Aptivus Side Effects Report #5206282-0
APTIVUS problem was reported by a Consumer or non-health professional from UNITED STATES on Sept 05, 2006. Female patient was diagnosed with hiv infection and was treated with APTIVUS. After drug was administered, patient experienced the following problems/side effects: headache. APTIVUS dosage: SEE TEXT, APTIVA/RITONAVIR 250/100MG, CAPSULE. Patient recovered.
Showing 1-50 of 133 Next >
Drug Information: Tipranavir
URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a606009.html
(tip ra' na veer)IMPORTANT WARNING:
| Tipranavir taken with ritonavir (Norvir) may cause bleeding in the brain. This condition may be life-threatening. Tell your doctor if you have recently had surgery or if you have recently been injured in any way. Also tell your doctor if you have a bleeding disorder such as hemophilia (condition in which the blood does not clot normally). Tell your doctor and pharmacist if you are taking any of the following medications: anticoagulants ('blood thinners') such as warfarin (Coumadin), aspirin, cilostazol (Pletal), clopidogrel (Plavix), or ticlopidine (Ticlid). If you need to get emergency medical treatment for any reason, be sure to tell all of the doctors who treat you that you are taking tipranavir. Call your doctor immediately if you experience unusual bruising or bleeding during your treatment with tipranavir.Tipranavir taken with ritonavir (Norvir) may cause liver damage that may be life-threatening. Tell your doctor if you have or have ever had hepatitis (swelling of the liver caused by a virus) or any other liver disease. Tell your doctor and pharmacist if you are taking acetaminophen (Tylenol, others); cholesterol lowering medications (statins) such as atorvastatin (Lipitor), lovastatin (Mevacor) and simvastatin (Zocor); iron products; isoniazid (INH, Nydrazid);methotrexate (Rheumatrex); niacin (nicotinic acid);rifampin (Rifadin, Rimactane); and salicylate pain relievers (aspirin, others). If you experience any of the following symptoms, stop taking tipranavir and call your doctor immediately: tiredness; flu-like symptoms; loss of appetite; upset stomach; pain, ache, swelling, or sensitivity on your right side below your ribs; yellowing of the skin or eyes; dark (tea-colored) urine; or pale bowel movements.Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests to check your body's response to tipranavir. Talk to your doctor about the risks of taking tipranavir. |
Why is this medication prescribed?
Tipranavir is used with ritonavir (Norvir) and at least two other medications to treat human immunodeficiency virus (HIV). Tipranavir is in a class of medications called protease inhibitors. It works by slowing the spread of HIV in the body. Tipranavir does not cure HIV infection and may not prevent you from developing HIV-related illnesses. Tipranavir does not prevent you from spreading HIV to other people.
How should this medicine be used?
Tipranavir comes as a capsule to take by mouth. It is usually taken with food and with ritonavir twice a day. Take tipranavir and ritonavir at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take tipranavir exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Do not take tipranavir without ritonavir.
Swallow the capsules whole; do not chew them.
Tipranavir controls HIV but does not cure it. Continue to take tipranavir even if you feel well. Do not stop taking tipranavir without talking to your doctor. If you stop taking tipranavir or skip doses, your condition may become more difficult to treat. When your supply of tipranavir starts to run low, get more from your doctor or pharmacist.
Ask your doctor or pharmacist for a copy of the manufacturer's information for the patient. Read this information carefully and ask your doctor or pharmacist if you have any questions.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking tipranavir,
- tell your doctor and pharmacist if you are allergic to tipranavir, ritonavir (Norvir), sulfa medications, any other medications, or any of the ingredients in tipranavir. Ask your pharmacist if you are unsure if a medication you are allergic to is a sulfa medication.
- do not take tipranavir if you are taking astemizole (Hismanal) (no longer available in the United States); cisapride (Propulsid) (no longer available in the United States); ergot medications for migraines such as dihydroergotamine (D.H.E. 45, Migranal), ergoloid mesylate (Hydergine), ergotamine (Bellamine, Cafergot, Ergomar, others), or methylergonovine (Methergine); certain medications for irregular heartbeat including amiodarone (Pacerone), bepridil (Vascor) (no longer available in the United States), flecainide (Tambocor), propafenone (Rythmol), or quinidine (Quinaglute); midazolam (Versed); pimozide (Orap); terfenadine (Seldane) (no longer available in the United States); and triazolam (Halcion).
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: antifungal medications such as fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), or voriconazole (Vfend); calcium-channel blockers such as diltiazem (Cardizem, Dilacor, Tiazac, others), felodipine (Lexxel, Plendil), nicardipine (Cardene), nisoldipine (Sular), or verapamil (Calan, Covera, Isoptin, Verelan, others); clarithromycin (Biaxin, in Prevpac); desipramine (Norpramin); disulfiram (Antabuse); immunosuppressants such as cyclosporine (Neoral, Sandimmune), sirolimus (Rapamune), or tacrolimus (Prograf); medications for diabetes such as glimepiride (Amaryl), glipizide (Glucotrol, in Metaglip), glyburide (Diabeta, Glycron, Glynase, Micronase, others), pioglitazone (Actos, in Actoplus), repaglinide (Prandin), or tolbutamide; certain medications for erectile dysfunction including sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra); other medications for HIV including amprenavir (Agenerase), lopinavir (in Kaletra), and saquinavir (Invirase); meperidine (Demerol, in Mepergan); methadone (Dolophine, Methadose); metronidazole (Flagyl); rifabutin (Mycobutin); and selective-serotonin reuptake inhibitors (SSRIs) such as fluoxetine (Prozac, Sarafem, in Symbyax), paroxetine (Paxil), or sertraline (Zoloft). Many other medications may also interact with tipranavir, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Be sure to talk to your doctor or pharmacist before you begin taking any new medications during your treatment with tipranavir. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- If you are taking didanosine, take it 2 hours before or 2 hours after you take tipranavir.
- If you are taking antacids, take them 2 hours before or 4 hours after you take tipranavir.
- tell your doctor what herbal products you are taking, especially St. John's wort.
- tell your doctor if you have or have ever had diabetes or high blood sugar; high blood cholesterol or triglycerides (blood fats); or an infection that comes and goes such as tuberculosis (TB), cytomegalovirus (CMV), herpes, shingles, or pneumonia.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking tipranavir, call your doctor. Do not breastfeed if you are infected with HIV or are taking tipranavir.
- you should know that tipranavir may decrease the effectiveness of hormonal contraceptives (birth control pills, rings, patches, and injections). Talk to your doctor about other ways to prevent pregnancy while you are taking this medication.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking tipranavir.
- plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Tipranavir may make your skin sensitive to sunlight.
- you should know that your body fat may increase or move to different areas of your body such as your breasts and upper back.
What special dietary instructions should I follow?
Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medicine.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
Tipranavir may cause hyperglycemia (high blood sugar). Call your doctor if you have any of the following symptoms of hyperglycemia:
- extreme thirst
- frequent urination
- extreme hunger
- weakness
- blurred vision
If high blood sugar is not treated, a serious, life-threatening condition called diabetic ketoacidosis could develop. Call your doctor immediately if you have any of the these symptoms:
- dry mouth
- upset stomach and vomiting
- shortness of breath
- breath that smells fruity
- decreased consciousness
Tipranavir may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- diarrhea
- vomiting
- headache
- difficulty falling asleep or staying asleep
- depression
Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately:
- fever, chills, cough, or other signs of infection
- rash
- itching
- throat tightness
- difficulty breathing or swallowing
- joint pain or stiffness
Tipranavir may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
What storage conditions are needed for this medicine?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store unopened bottles of tipranavir capsules in the refrigerator. Store opened bottles of tipranavir at room temperature, and away from excess heat and moisture (not in the bathroom). Throw away any unused tipranavir capsules 60 days after you open the bottle Mark the date you open the bottle of tipranavir on the label so you will know when it is time to throw the remaining medication away. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
What other information should I know?
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
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