Asparaginase Safety Questions, Asparaginase Answers
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Asparaginase Safety Reports
Total Asparaginase reports: 5.Asparaginase FDA safety alerts: No.
Reported deaths: 1 Reported hospitalizations: 3.
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Reported Asparaginase Side Effects: thrombosis, convulsion, hypotension, bacterial sepsis, hyperosmolar state, hyperglycaemia, pyrexia, myalgia.
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Asparaginase Side Effects Report #5211891-9
Pharmacist from UNITED STATES reported ASPARAGINASE problem on Jan 16, 2007. Male patient, 21 years of age, was treated with ASPARAGINASE. After drug was administered, patient experienced the following problems/side effects: myalgia, pyrexia. ASPARAGINASE dosage: unknown. During the same period patient was treated with FILGRASTIM. Patient was hospitalized. Patient recovered.
Asparaginase Side Effects Report #5293721-2
ASPARAGINASE problem was reported by a Health Professional from FRANCE on Mar 20, 2007. Female patient was diagnosed with acute lymphocytic leukaemia and was treated with ASPARAGINASE. After drug was administered, patient experienced the following problems/side effects: convulsion, thrombosis. ASPARAGINASE dosage: unknown. During the same period patient was treated with VINCRISTINE, PREDNISONE, DAUNORUBICIN, ORAL CONTRACEPTIVE NOS. Patient recovered.
Asparaginase Side Effects Report #5293722-4
Health Professional from FRANCE reported ASPARAGINASE problem on Mar 02, 2007. Female patient was diagnosed with acute lymphocytic leukaemia and was treated with ASPARAGINASE. After drug was administered, patient experienced the following problems/side effects: convulsion, thrombosis. ASPARAGINASE dosage: unknown. During the same period patient was treated with VINCRISTINE, PREDNISONE, DAUNORUBICIN, ORAL CONTRACEPTIVE NOS. Patient recovered.
Asparaginase Side Effects Report #5158302-X
ASPARAGINASE problem was reported by a Pharmacist from UNITED STATES on Nov 21, 2006. Male patient, 62 years of age, was treated with ASPARAGINASE. After drug was administered, patient experienced the following problems/side effects: hyperglycaemia, hyperosmolar state. ASPARAGINASE dosage: unknown. During the same period patient was treated with INSULIN, GLUCOPHAGE, ATENOLOL, COUMADIN, LISINOPRIL. Patient was hospitalized. Patient died.
Asparaginase Side Effects Report #5188004-5
Physician from UNITED KINGDOM reported ASPARAGINASE problem on Dec 01, 2006. Female patient, child 9 years of age, was diagnosed with leukaemia, fungal infection and was treated with ASPARAGINASE. After drug was administered, patient experienced the following problems/side effects: bacterial sepsis, hypotension. ASPARAGINASE dosage: unknown. During the same period patient was treated with DECADRON, DOXORUBICIN, POSACONAZOLE, VINCRISTINE SULPHATE. Patient was hospitalized. Patient recovered.
