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Astomin Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Renal Failure, Lung Infiltration, Abasia, Neoplasm Malignant, Dehydration, Cellulitis, Pyrexia, Lymphadenopathy, Calcification Of Muscle (8394418-2)
on May 23, 2012 Male from JAPAN , weighting 132.3 lb, was treated with Astomin. Directly after, patient experienced the unwanted or unexpected Astomin side effects: renal failure, lung infiltration, abasia, neoplasm malignant, dehydration, cellulitis, pyrexia, lymphadenopathy, calcification of muscle. Astomin dosage: 3 Df, Unk.
Associated medications used:
  • Red Blood Cells, Concentrated (2 U, Every Week)
  • Exjade (1000 Mg, Daily)
  • Lansoprazole (15 Mg, Unk)
  • Urief (8 Mg, Unk)


Performance Status Decreased, Upper Gastrointestinal Haemorrhage, Blood Creatinine Increased, Rash, Blood Urea Increased, Anaphylactic Shock, Diarrhoea (7944978-8)
Patient was taking Astomin. Patient felt the following Astomin side effects: performance status decreased, upper gastrointestinal haemorrhage, blood creatinine increased, rash, blood urea increased, anaphylactic shock, diarrhoea on Nov 16, 2011 from JAPAN Additional patient health information: Female , weighting 88.18 lb, . Astomin dosage: 30 Mg, Uid/qd.
Multiple prescriptions taken:
  • Naproxen (300 Mg, Uid/qd)
  • Gemcitabine Hydrochloride (Unk)
  • Primperan Tab (15 Mg, Uid/qd)
  • Aldactone (50 Mg, Uid/qd)
  • Tramadol Hydrochloride (100 Unk, Uid/qd)
  • Fentanyl Citrate (1 Mg, Uid/qd)
  • Omeprazole (20 Mg, Uid/qd)
  • Lasix (20 Mg, Uid/qd)
Patient was hospitalized.

Tremor, Encephalitis, Sensory Disturbance, Tinnitus, Herpes Zoster Oticus (7650375-5)
Adverse event was reported on Jul 11, 2011 by a Patient taking Astomin (dimemorfan Phosphate) (Dosage: N/A) . Location: JAPAN , 13 years of age, After Astomin was administered, patient encountered several Astomin side effects: tremor, encephalitis, sensory disturbance, tinnitus, herpes zoster oticus.
Multiple concurrent drugs taken:
  • Mucodyne (carbocisteine)
  • Ibuprofen
  • Immune Globulin (human)
  • Valtrex
  • Intal
Patient was hospitalized.

Duodenal Perforation, Pneumoretroperitoneum, Diverticulitis, Gastroduodenal Ulcer, Disseminated Intravascular Coagulation (7334911-4)
on Mar 02, 2011 Female from JAPAN , weighting 116.8 lb, was treated with Astomin. Directly after, patient experienced the unwanted or unexpected Astomin side effects: duodenal perforation, pneumoretroperitoneum, diverticulitis, gastroduodenal ulcer, disseminated intravascular coagulation. Astomin dosage: N/A.
Associated medications used:
  • Avastin
  • Mucodyne
  • Glakay
  • Elplat (Dosage Is Uncertain.)
  • Decadron
  • Omepra
  • Indisetron Hydrochloride
  • Celecoxib
Patient was hospitalized.


Hepatic Function Abnormal, Blood Lactate Dehydrogenase Increased, Haematuria, Aspartate Aminotransferase Increased, Leucine Aminopeptidase Increased, Bilirubin Conjugated Increased, Blood Alkaline Phosphatase Increased, Nephrolithiasis, Blood Bilirubin Increased (7320707-6)
on Feb 22, 2011 Female from JAPAN , 65 years of age, weighting 130.5 lb, was diagnosed with
  • bronchitis
and was treated with Astomin. Patient felt the following Astomin side effects: hepatic function abnormal, blood lactate dehydrogenase increased, haematuria, aspartate aminotransferase increased, leucine aminopeptidase increased, bilirubin conjugated increased, blood alkaline phosphatase increased, nephrolithiasis, blood bilirubin increased. Astomin dosage: Unk.
Multiple prescriptions taken:
  • Mucodyne (Unk)
  • Caduet (Unk)
  • Garenoxacin Mesilate (Unk)
  • Caduet
Patient was hospitalized.

Hepatic Function Abnormal, Platelet Count Decreased, Tumour Lysis Syndrome, Hypocalcaemia, Bradycardia, Renal Failure, Cardio-respiratory Arrest, Hyperkalaemia, Multi-organ Failure (7230419-5)
Patient was taking Astomin. After Astomin was administered, patient encountered several Astomin side effects: hepatic function abnormal, platelet count decreased, tumour lysis syndrome, hypocalcaemia, bradycardia, renal failure, cardio-respiratory arrest, hyperkalaemia, multi-organ failure on Jan 13, 2011 from JAPAN Additional patient health information: Female , 44 years of age, weighting 87.52 lb, . Astomin dosage: 10 Mg, 3x/day.
Multiple concurrent drugs taken:
  • Urso 250 (50 Mg, 3x/day)
  • Nauzelin (10 Mg, As Needed)
  • Mucodyne (500 Mg, 3x/day)
  • Rhythmy (1 Mg, As Needed)
  • Sutent (37.5 Mg, 1x/day)
  • Pursennid (12 Mg, As Needed)
  • Calonal (200 Mg, As Needed)
  • Codeine Phosphate (Unk)


Gastrointestinal Tract Adenoma, Influenza, Pneumonia, Polypectomy, Reflux Oesophagitis (5285949-2)
Adverse event was reported on Mar 23, 2007 by a Male taking Astomin (Dosage: N/A) . Location: JAPAN , 47 years of age, Directly after, patient experienced the unwanted or unexpected Astomin side effects: gastrointestinal tract adenoma, influenza, pneumonia, polypectomy, reflux oesophagitis.
Associated medications used:
  • Laxoberon
  • Magcorol P
  • Pursennid
  • Diovan (40 Mg, Qd)
  • Diovan (80 Mg, Qd)
  • Norvasc
  • Ferromia
  • Cinal
Patient was hospitalized.

Gastrointestinal Tract Adenoma, Influenza, Pneumonia, Polypectomy, Reflux Oesophagitis (5238123-X)
on Feb 02, 2007 Male from JAPAN , 47 years of age, was treated with Astomin. Patient felt the following Astomin side effects: gastrointestinal tract adenoma, influenza, pneumonia, polypectomy, reflux oesophagitis. Astomin dosage: N/A.
Multiple prescriptions taken:
  • Laxoberon
  • Magcorol P
  • Pursennid
  • Diovan (40 Mg, Qd)
  • Diovan (80 Mg, Qd)
  • Norvasc
  • Ferromia
  • Cinal
Patient was hospitalized.

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Astomin Information

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Side Effects reported to FDA: 8. View Astomin Adverse Reports

Astomin safety alerts: No

Reported deaths: 2

Reported hospitalizations: 5

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