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Avastatin Side Effects

Common Avastatin Side Effects


The most commonly reported Avastatin side effects (click to view or check a box to report):

Diarrhoea (1)
Endocarditis (1)
Groin Abscess (1)
Death (1)
Confusional State (1)
White Blood Cell Count Decreased (1)
Blood Pressure Increased (1)
Chills (1)
Haemoglobin Decreased (1)
Incoherent (1)
Pulmonary Embolism (1)
Stomatitis (1)
Vasculitis (1)
Neutropenia (1)
Nausea (1)
Intestinal Obstruction (1)
Lower Gastrointestinal Haemorrhage (1)
Blood Pressure Fluctuation (1)


If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

Avastatin Side Effects Reported to FDA

The following Avastatin reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.


The appearance of Avastatin on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

This is a report of a 87-year-old male patient (weight: NA) from US, suffering from the following symptoms/conditions: NA, who was treated with Avastatin (dosage: 1 Every Six Weeks Intraoctular, start time: Mar 18, 2009), combined with: NA. and developed a serious reaction and side effect(s). The consumer presented with:
    which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Avastatin treatment in male patients, resulting in death side effect.

    White Blood Cell Count Decreased, Groin Abscess, Haemoglobin Decreased, Blood Pressure Increased
    This report suggests a potential Avastatin (bevacizumab) (bevacizumab) White Blood Cell Count Decreased, Groin Abscess, Haemoglobin Decreased, Blood Pressure Increased side effect(s) that can have serious consequences. A 43-year-old female patient (weight: NA) from UNITED STATES was diagnosed with the following symptoms/conditions: neoplasm and used Avastatin (bevacizumab) (bevacizumab) (dosage: 1088 Mg) starting Jan 06, 2011. Soon after starting Avastatin (bevacizumab) (bevacizumab) the patient began experiencing various side effects, including:
    • White Blood Cell Count Decreased
    • Groin Abscess
    • Haemoglobin Decreased
    • Blood Pressure Increased
    Drugs used concurrently:
    • Carboplatin (900 Mg)
    • Abraxane (185 Mg, Intravenous)
    The patient was hospitalized. Although Avastatin (bevacizumab) (bevacizumab) demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as white blood cell count decreased, may still occur.

    Blood Pressure Fluctuation, Nausea
    This Blood Pressure Fluctuation, Nausea problem was reported by a health professional from UNITED STATES. A 49-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: colorectal cancer metastatic. On NS this consumer started treatment with Avastatin Not Provided (dosage: NA). The following drugs were being taken at the same time:
    • Fluorouracil
    When commencing Avastatin Not Provided, the patient experienced the following unwanted symptoms/side effects:
    • Blood Pressure Fluctuation
    • Nausea
    Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as blood pressure fluctuation, may become evident only after a product is in use by the general population.

    Intestinal Obstruction
    This is a report of a 63-year-old female patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: ovarian cancer and was treated with Avastatin(bevacizumab) Powder And Solvent For Solution For Infusion, 1 (dosage: NA) starting NS. Concurrently used drugs: NA.Soon after that, the consumer experienced the following side effects:
    • Intestinal Obstruction
    This opens a possibility that Avastatin(bevacizumab) Powder And Solvent For Solution For Infusion, 1 treatment could cause the above reactions, including intestinal obstruction, and some female subjects may be more susceptible.


    Neutropenia, Stomatitis
    A 43-year-old female patient (weight: NA) from UNITED STATES with the following symptoms/conditions: neuroendocrine carcinoma started Avastatin(bevacizumab) Powder And Solvent For Solution For Infusion, 1 treatment (dosage: 5 Mg/kg, Intravenous) on NS. Soon after starting Avastatin(bevacizumab) Powder And Solvent For Solution For Infusion, 1 treatment, the subject experienced various side effects, including:
    • Neutropenia
    • Stomatitis
    Concurrently used drugs:
    • Fluorouracil (400 Mg/m2, Intravenous)
    • Doxorubicin Hcl (40 Mg/m2, Intravenous)
    • Streptozocin(streptozocin) (400 Mg/m2, Intravenous)
    • Protonix
    The patient was hospitalized. This finding indicates that some female patients could be more vulnerable to Avastatin(bevacizumab) Powder And Solvent For Solution For Infusion, 1.

    Pulmonary Embolism
    A 37-year-old female patient from UNITED STATES (weight: NA) experienced symptoms, such as: ovarian cancer and was treated with Avastatin(bevacizumab) Powder And Solvent For Solution For Infusion, 1(dosage: NA). The treatment was initiated on NS. After that a consumer reported the following side effect(s):
    • Pulmonary Embolism
    Concurrently used drugs, which potentially could have contributed to side effect(s) or affected Avastatin(bevacizumab) Powder And Solvent For Solution For Infusion, 1 efficacy: NA.

    Lower Gastrointestinal Haemorrhage
    In this report, Avastatin(bevacizumab) Powder And Solvent For Solution For Infusion, 1 was administered for the following condition: colon cancer.A 53-year-old male consumer from UNITED STATES (weight: NA) started Avastatin(bevacizumab) Powder And Solvent For Solution For Infusion, 1 treatment (dosage: 400 Mg, Q14d, Intravenous) on Feb 01, 2007.Sometime after starting the treatment, the patient complained of the following side effect(s):
    • Lower Gastrointestinal Haemorrhage
    A possible interaction with other drugs could have contributed to this reaction:
    • Oxaliplatin
    • Fluorouracil
    • Synthroid
    The patient was hospitalized.Establishing a causal relationship between a specific drug and consumer's side effects is complex, but it is possible that in this report Avastatin(bevacizumab) Powder And Solvent For Solution For Infusion, 1 treatment could be related to the listed above side effect(s).

    Chills, Confusional State, Diarrhoea, Endocarditis, Incoherent, Vasculitis
    This is a report of the following Avastatin (bevacizumab) side effect(s):
    • Chills
    • Confusional State
    • Diarrhoea
    • Endocarditis
    • Incoherent
    • Vasculitis
    A 67-year-old male patient from (weight: NA) presented with the following condition: metastatic renal cell carcinoma and received a treatment with Avastatin (bevacizumab) (dosage: 10 Mg/kg , Q2w, Intravenous) starting: Jan 11, 2005.The following concurrently used drugs could have generated interactions:
    • Flomax
    • Ditropan
    • Calcium (calcium Nos)
    • Iron (iron Nos)
    • Multivitamin (multivitamins Nos)
    • Zometa
    • Tarceva
    • Atenolol
    This report suggests that a Avastatin (bevacizumab) treatment could be associated with the listed above side effect(s).



    Keep Track of Side Effects

    Note Your Observations

    It is really important to keep of your symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

    Why Your Notes are Important

    Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


    Discuss Avastatin Side Effects

    Did You Have a Avastatin Side Effect?

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    Yes, Moderate
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    How Effective is Avastatin for You?

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    Effective
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    Avastatin Safety Alerts, Active Ingredients, Usage Information

    NDC0093-0771
    TypeHUMAN PRESCRIPTION DRUG
    Proprietary NamePravastatin Sodium
    NamePravastatin Sodium
    Dosage FormTABLET
    RouteORAL
    On market since20060425
    LabelerTeva Pharmaceuticals USA Inc
    Active Ingredient(s)PRAVASTATIN SODIUM
    Strength(s)10
    Unit(s)mg/1
    Pharma ClassHMG-CoA Reductase Inhibitor [EPC],Hydroxymethylglutaryl-CoA Reductase Inhibitors [MoA]

    More About Avastatin

    Side Effects reported to FDA: 8

    Avastatin safety alerts: No

    Reported deaths: 1

    Reported hospitalizations: 2

    Latest Avastatin clinical trials