Azathioprine Side Effects
How can Azathioprine Side Effects affect You? | PatientsVille.com
View and Submit Azathioprine Side Effects
Your Azathioprine Side Effect submission can play a very important role. Reporting your experience could help identify an unknown risk and inform other patients and health care professionals.
Record and Track Your Side Effects
It is very important to keep track of all side effects and discuss them with your doctor. If you think you may have a medical emergency, call your doctor or 911 immediately.
Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Alternative AZATHIOPRINE Names:AZATHIOPR
Active Ingredient: AZATHIOPR
Side Effects reported to FDA: 1540. View Azathioprine Adverse Reports
Reported deaths: 247
Reported hospitalizations: 698
Tumor Necrosis Factor (TNF) blockers, Azathioprine and/or Mercaptopurine: Update on Reports of Hepatosplenic T-Cell Lymphoma in Adolescents and Young Adults
[UPDATED 11/04/2011] Healthcare professionals should remain vigilant for cases of malignancy in patients treated with TNF blockers, and report such cases to MedWatch. The reports should include:
AUDIENCE: Rheumatology, Gastroenterology, Oncology, Dermatology
ISSUE: FDA continues to receive reports of a rare cancer of white blood cells (known as Hepatosplenic T-Cell Lymphoma or HSTCL, primarily in adolescents and young adults being treated for Crohn’s disease and ulcerative colitis with medicines known as tumor necrosis factors (TNF) blockers, as well as with azathioprine, and/or mercaptopurine. TNF blockers include Remicade (infliximab), Enbrel (etanercept), Humira (adalimumab), Cimzia (certolizumab pegol) and Simponi (golimumab).
BACKGROUND: HSTCL is an aggressive (fast-growing) cancer and is usually fatal. The majority of cases reported were in patients being treated for Crohn’s disease or ulcerative colitis, but also included a patient being treated for psoriasis and two patients being treated for rheumatoid arthritis. FDA is now updating the number of reported cases of HSTCL.
Although most reported cases of HSTCL occurred in patients treated with a combination of medicines known to suppress the immune system, including the TNF blockers, azathioprine, and/or mercaptopurine, there have been cases reported in patients receiving azathioprine or mercaptopurine alone.
Read the Drug Safety Communications for other specific recommendations for Healthcare Professionals and Patients and the Data Summary for additional information.
Healthcare professionals and patients are encouraged to report adverse events or side effects related to the use of these products to the FDA's MedWatch Safety Information and Adverse Event Reporting Program:
Previous MedWatch Alert:
Did You Have a Azathioprine Side Effect?
How Effective is Azathioprine for You?
Azathioprine Adverse Reactions
Pyrexia ( 101 Reports)|Pancytopenia ( 78 Reports)|Crohn's Disease ( 63 Reports)|Diarrhoea ( 63 Reports)|Fatigue ( 62 Reports)|Nausea ( 58 Reports)|Abdominal Pain ( 52 Reports)|Dyspnoea ( 52 Reports)|Vomiting ( 48 Reports)|Bone Marrow Failure ( 45 Reports)|Arthralgia ( 44 Reports)|Leukopenia ( 43 Reports)|Epstein-barr Virus Infection ( 41 Reports)|Anaemia ( 38 Reports)|Condition Aggravated ( 38 Reports)|Pneumonia ( 38 Reports)|Asthenia ( 37 Reports)|Headache ( 37 Reports)|Malaise ( 34 Reports)|Weight Decreased ( 33 Reports)|Chills ( 32 Reports)|Cytomegalovirus Infection ( 30 Reports)|Epstein-barr Virus Associated Lymphoproliferative Disorder ( 30 Reports)|Histiocytosis Haematophagic ( 28 Reports)|Hypotension ( 27 Reports)|Cough ( 26 Reports)|Haemoglobin Decreased ( 26 Reports)|Myalgia ( 26 Reports)|Sepsis ( 26 Reports)|C-reactive Protein Increased ( 25 Reports)|