Bendamustine Side Effects
How can Bendamustine Side Effects affect You? | PatientsVille.com
View and Submit Bendamustine Side Effects
Your Bendamustine Side Effect submission can play a very important role. Reporting your experience could help identify an unknown risk and inform other patients and health care professionals.
Record and Track Your Side Effects
It is very important to keep track of all side effects and discuss them with your doctor. If you think you may have a medical emergency, call your doctor or 911 immediately.
Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Side Effects reported to FDA: 470. View Bendamustine Adverse Reports
Bendamustine safety alerts: 2012
Reported deaths: 52
Reported hospitalizations: 172
Treanda (bendamustine HCL): Recall - Particulate Matter in Vial
AUDIENCE: Risk Manager, Oncology, Pharmacy
ISSUE: Cephalon, Inc. notified healthcare professionals of a recall of Treanda (bendamustine HCL) for Injection 25mg/8mL, lot TB30111, expiration date 12/2012. This product lot is being recalled due to the presence of particulate matter found in a single vial, which has been identified as glass fragments. Potential adverse events after intravenous administration of solutions containing particulates may present as an emboli and result in disruption of blood flow causing tissue/organ damage, especially in vulnerable patients such as those undergoing surgery, immunosuppressed individuals, and the elderly, as well as patients with micro or macrovasular disease, such as cardiac and renal disease, who may be more at risk since their vasculature and end organs are already compromised.
The affected Treanda lot is packaged in 8 mL vials and was distributed to wholesalers and distributors nationwide between March 22, 2011 and October 5, 2011.
BACKGROUND: Treanda (bendamustine HCL) for Injection 25mg/8mL is indicated for the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin’s lymphoma (NHL) that has progressed during or within 6 months of treatment with rituximab-containing regimen.
RECOMMENDATION: Recipients of the subject lot have been previously notified of this recall via overnight notification on 11/18/11. Wholesalers, retailers, hospitals and health care professionals who have lot TB30111 in their possession are instructed to immediately cease using the product and immediately quarantine product for return.
Healthcare professionals and patients are encouraged to report adverse events or side effects related to the use of these products to the FDA's MedWatch Safety Information and Adverse Event Reporting Program:
[01/27/2012 - Press Release - Cephalon, Inc.]
Did You Have a Bendamustine Side Effect?
How Effective is Bendamustine for You?
Bendamustine Adverse Reactions
Neutrophil Count Decreased ( 54 Reports)|Lymphocyte Count Decreased ( 52 Reports)|Pyrexia ( 51 Reports)|White Blood Cell Count Decreased ( 48 Reports)|Platelet Count Decreased ( 41 Reports)|Febrile Neutropenia ( 35 Reports)|Cytomegalovirus Infection ( 29 Reports)|Anaemia ( 27 Reports)|Nausea ( 25 Reports)|Pneumonia ( 25 Reports)|Diarrhoea ( 22 Reports)|Dyspnoea ( 19 Reports)|Neutropenia ( 18 Reports)|Pancytopenia ( 18 Reports)|Infection ( 16 Reports)|Leukopenia ( 16 Reports)|C-reactive Protein Increased ( 15 Reports)|Decreased Appetite ( 14 Reports)|Fatigue ( 14 Reports)|Phlebitis ( 14 Reports)|Sepsis ( 14 Reports)|Thrombocytopenia ( 14 Reports)|Vomiting ( 14 Reports)|Dehydration ( 13 Reports)|Lymphopenia ( 13 Reports)|Pneumocystis Jiroveci Pneumonia ( 13 Reports)|Haemoglobin Decreased ( 12 Reports)|Bone Marrow Failure ( 10 Reports)|Haemolytic Anaemia ( 10 Reports)|Pleural Effusion ( 10 Reports)|