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Benzhexol Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Cardiac Arrest (8234314-4)
on Mar 19, 2012 Male from CHINA , weighting 125.7 lb, was diagnosed with
  • extrapyramidal disorder
  • schizophrenia
  • tachycardia
  • akathisia
and was treated with Benzhexol Hydrochloride. Directly after, patient experienced the unwanted or unexpected Benzhexol side effects: cardiac arrest. Benzhexol Hydrochloride dosage: N/A.
Associated medications used:
  • Invega
  • Propranolol Hydrochloride
  • Alprazolam
Patient was hospitalized.

Memory Impairment, Cerebral Infarction, Treatment Noncompliance (8119365-2)
Patient was taking Benzhexol Hydrochloride. Patient felt the following Benzhexol side effects: memory impairment, cerebral infarction, treatment noncompliance on Feb 01, 2012 from CHINA Additional patient health information: Female , 64 years of age, . Benzhexol Hydrochloride dosage: N/A.
Multiple prescriptions taken:
  • Risperdal
  • Risperdal


Psychotic Disorder (8011839-8)
Adverse event was reported on Dec 20, 2011 by a Male taking Benzhexol (Dosage: N/A) . Location: CHINA , weighting 121.3 lb, After Benzhexol was administered, patient encountered several Benzhexol side effects: psychotic disorder.
Multiple concurrent drugs taken:
  • Clonazepam (4 Mg Twice In The Evening)
  • Clonazepam (20 Mg Stat (immediately))
  • Clonazepam
  • Clonazepam (4 Mg Orally Twice In The Evening)
  • Paliperidone
Patient was hospitalized.

Psychiatric Symptom (7932792-9)
on Nov 11, 2011 Male from JAPAN , 30 years of age, was treated with Benzhexol. Directly after, patient experienced the unwanted or unexpected Benzhexol side effects: psychiatric symptom. Benzhexol dosage: N/A.
Associated medications used:
  • Risperidone
  • Aripiprazole
  • Abilify
Patient was hospitalized.


Schizophrenia (7513281-2)
on May 20, 2011 Male from HONG KONG , weighting 148.2 lb, was treated with Benzhexol. Patient felt the following Benzhexol side effects: schizophrenia. Benzhexol dosage: N/A. Patient was hospitalized.

Restlessness, Insomnia (7440415-0)
Patient was taking Benzhexol. After Benzhexol was administered, patient encountered several Benzhexol side effects: restlessness, insomnia on Apr 21, 2011 from JAPAN Additional patient health information: Male , 29 years of age, . Benzhexol dosage: N/A.
Multiple concurrent drugs taken:
  • Abilify (6mg 8-22mar11(15d) 12mg 23mar-7apr11(16d) 18mg 8-12apr11(5d))
  • Risperidone
  • Zolpidem
  • Olanzapine (Olanzapine Orodispersible Tabs)
Patient was hospitalized.

Social Problem (7438121-1)
Adverse event was reported on Apr 14, 2011 by a Male taking Benzhexol (Dosage: N/A) . Location: JAPAN , 29 years of age, Directly after, patient experienced the unwanted or unexpected Benzhexol side effects: social problem.
Associated medications used:
  • Risperidone
  • Zolpidem
  • Abilify (6mg 8-22mar11(15d) 12mg 23mar-7apr11(16d) 18mg 8-12apr11(5d))
  • Olanzapine (Olanzapine Orodispersible Tabs)
Patient was hospitalized.

Suicide Attempt, Somnolence, Intentional Overdose, Hyperhidrosis (7351882-5)
on Mar 09, 2011 Female from CHINA , 22 years of age, was diagnosed with
  • schizophrenia
and was treated with Benzhexol. Patient felt the following Benzhexol side effects: suicide attempt, somnolence, intentional overdose, hyperhidrosis. Benzhexol dosage: N/A.
Multiple prescriptions taken:
  • Risperdal
  • Risperdal
  • Risperdal
  • Risperdal


Amnesia, Hallucinations, Mixed, Vision Blurred (5050535-6)
on Jun 29, 2006 Male from UNITED KINGDOM , 54 years of age, was diagnosed with
  • dystonia
  • tremor
and was treated with Benzhexol (trihexyphenidyl). After Benzhexol was administered, patient encountered several Benzhexol side effects: amnesia, hallucinations, mixed, vision blurred. Benzhexol (trihexyphenidyl) dosage: 1 Mg 1x Per 1 Day.

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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