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Bevacizumab Safety Reports

Total Bevacizumab reports: 874.
Bevacizumab FDA safety alerts: 2004 2005 2006 2007 .
Reported deaths: 194    Reported hospitalizations: 649.
Take Bevacizumab Side Effects Survey or Share Your Bevacizumab Story.
Reported Bevacizumab Side Effects: pyrexia, dehydration, diarrhoea, nausea, vomiting, asthenia, disease progression, pulmonary embolism, death, renal failure acute, anaemia haemolytic autoimmune.
More About Bevacizumab.

< Previous  Showing 101-150 of 874 Next >

Bevacizumab Side Effects Report #5288609-7
Physician from UNITED KINGDOM reported BEVACIZUMAB problem on Mar 22, 2007. Male patient was diagnosed with colorectal cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: mallory-weiss syndrome. BEVACIZUMAB dosage: 427 MG, QD. During the same period patient was treated with CAPECITABINE, OXALIPLATIN, CETUXIMAB, OMEPRAZOLE. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5289245-9
BEVACIZUMAB problem was reported by a Physician from UNITED STATES on Apr 03, 2007. Male patient, 72 years of age, weighting 168.0 lb, was diagnosed with lung neoplasm malignant and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: haemoglobin decreased, haemoptysis. BEVACIZUMAB dosage: 1100 MG ONCE IV DRIP. Patient died on 03/23/2007.

Bevacizumab Side Effects Report #5289845-6
Physician from UNITED STATES reported BEVACIZUMAB problem on Apr 02, 2007. Male patient, weighting 142.0 lb, was diagnosed with colon cancer metastatic and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: pleural effusion. BEVACIZUMAB dosage: 330 MG, Q2W. During the same period patient was treated with CETUXIMAB, FLUOROURACIL, LEUCOVORIN CALCIUM, FOSAMAX, ZOCOR, TOPROL, ENALAPRIL MALEATE, AMARYL. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5289881-X
BEVACIZUMAB problem was reported by a Physician from UNITED STATES on Apr 04, 2007. Male patient, weighting 181.9 lb, was diagnosed with non-small cell lung cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: haemorrhage, neoplasm malignant, penile pain. BEVACIZUMAB dosage: 10 MG/KG, DAYS 1+15. During the same period patient was treated with ERLOTINIB, PEMETREXED, LIPITOR, FLOMAX, ENALAPRIL MALEATE, ACTOS, CLARITIN, ATENOLOL. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5290173-3
Health Professional from UNITED STATES reported BEVACIZUMAB problem on Mar 20, 2007. Female patient, 27 years of age, was diagnosed with breast cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: medical device complication. BEVACIZUMAB dosage: 15 MG/KG, Q3W, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, METHOTREXATE. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5290484-1
BEVACIZUMAB problem was reported by a Physician from UNITED STATES on Apr 05, 2007. Male patient, 71 years of age, weighting 181.0 lb, was diagnosed with non-small cell lung cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: bladder cancer, haematocrit decreased, haemorrhage, penile pain. BEVACIZUMAB dosage: 10 MG/KG DAYS 1+15 IV. During the same period patient was treated with PEMETREXED, ERLOTINIB, LIPITOR, FLOMAX, VASOTEC, ACTOS, CLARITIN, CHLORTHALID. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5290488-9
Consumer or non-health professional from UNITED STATES reported BEVACIZUMAB problem on Apr 05, 2007. Male patient was diagnosed with glioblastoma multiforme and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: dehydration, fall, hyponatraemia, nausea, vomiting. BEVACIZUMAB dosage: 10 MG/KG. During the same period patient was treated with ERLOTINIB, TOPROL, PREVACID, RITALIN, KEPPRA, DECADRON, LOVASTATIN, COLACE. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5291215-1
BEVACIZUMAB problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Apr 08, 2007. Female patient, weighting 88.18 lb, was diagnosed with breast cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: hypovolaemia. BEVACIZUMAB dosage: 10 MG/KG, Q2W. During the same period patient was treated with PACLITAXEL, SKENAN, ACTISKENAN, ZOMETA. Patient died on 01/19/2007.

Bevacizumab Side Effects Report #5292036-6
Physician from UNITED KINGDOM reported BEVACIZUMAB problem on Apr 08, 2007. Female patient was diagnosed with colon cancer, hypertension and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: angioedema. BEVACIZUMAB dosage: 440 MG, Q2W. During the same period patient was treated with OXALIPLATIN, LEUCOVORIN CALCIUM, GOPTEN, CALTRATE, DILTIAZEM, INDAPAMIDE, ZOTON, NAPROXEN. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5292260-2
BEVACIZUMAB problem was reported by a Physician from UNITED STATES on Apr 04, 2007. Female patient, weighting 132.3 lb, was diagnosed with urinary tract infection, insomnia, bronchitis chronic, hypertension and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: cystitis haemorrhagic. BEVACIZUMAB dosage: unknown. During the same period patient was treated with DOCETAXEL, OXALIPLATIN, KEFLEX, AMBIEN, DECADRON, SPIRIVA, AVALIDE. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5292434-0
Consumer or non-health professional from UNITED STATES reported BEVACIZUMAB problem on Apr 04, 2007. Female patient, weighting 207.2 lb, was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: failure to thrive, oesophagitis. BEVACIZUMAB dosage: 10 MG/KG, Q28D. During the same period patient was treated with IRINOTECAN, CARBOPLATIN, VYTORIN, ATACAND, PREMARIN, LUNESTA, MELOXICAM, SERTRALINE. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5292440-6
BEVACIZUMAB problem was reported by a Physician from UNITED STATES on Apr 03, 2007. Male patient, 26 years of age, was diagnosed with colorectal cancer metastatic and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: nephritis interstitial. BEVACIZUMAB dosage: 5 MG/KG, Q2W. During the same period patient was treated with MORPHINE. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5292511-4
Physician from UNITED KINGDOM reported BEVACIZUMAB problem on Mar 26, 2007. Female patient, weighting 166.0 lb, was diagnosed with colorectal cancer metastatic and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: renal failure acute. BEVACIZUMAB dosage: 565 MG, Q3W. During the same period patient was treated with CAPECITABINE, OXALIPLATIN, LISINOPRIL AND HYDROCHLOROTHIAZIDE, METOPROLOL SUCCINATE, LANTUS, SULAR, LIPITOR, PROCRIT. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5293235-X
BEVACIZUMAB problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 04, 2007. Male patient, weighting 142.0 lb, was diagnosed with hunger, anxiety, nausea and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: diabetic ketoacidosis. BEVACIZUMAB dosage: 5 MG/KG, Q2W. During the same period patient was treated with LEUCOVORIN CALCIUM, FLUOROURACIL, OXALIPLATIN, MEGACE, ALPRAZOLAM, DECADRON, ENDOCET, COMPAZINE. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5293620-6
Consumer or non-health professional from UNITED KINGDOM reported BEVACIZUMAB problem on Mar 30, 2007. Male patient, weighting 149.9 lb, was diagnosed with metastatic renal cell carcinoma and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: dyskinesia, gait disturbance, gliosis, hemiparesis, speech disorder, strabismus, weight decreased. BEVACIZUMAB dosage: 10 MG/KG, Q2W. During the same period patient was treated with INTERFERON ALPHA, PARACETAMOL, ATACAND, ZOMETA, MOVICOL. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5294046-1
BEVACIZUMAB problem was reported by a Physician from UNITED STATES on Mar 23, 2007. Male patient, 26 years of age, was diagnosed with renal cancer metastatic and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: nephritis interstitial, renal failure acute. BEVACIZUMAB dosage: 5 MG/KG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5295197-8
Physician from UNITED KINGDOM reported BEVACIZUMAB problem on Mar 28, 2007. Male patient was diagnosed with non-small cell lung cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: abdominal distension, agitation, bowel sounds abnormal, constipation, cyanosis, disease progression, dyspepsia, fall, left ventricular failure. BEVACIZUMAB dosage: 1380 MG, QD. During the same period patient was treated with ERLOTINIB, IPRATROPIUM BROMIDE, ASPIRIN, TRIATEC, ADALAT, DAFALGAN, PANTOZOL, HEPARIN. Patient was hospitalized. Patient died on 12/11/2006.

Bevacizumab Side Effects Report #5295387-4
BEVACIZUMAB problem was reported by a Health Professional from UNITED STATES on Apr 04, 2007. Female patient, weighting 93.98 lb, was diagnosed with colon cancer metastatic and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: pancreatitis. BEVACIZUMAB dosage: 5 MG/KG, 2/MONTH. During the same period patient was treated with CAPECITABINE. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5295457-0
Health Professional from UNITED STATES reported BEVACIZUMAB problem on Apr 10, 2007. Male patient, weighting 181.9 lb, was diagnosed with non-small cell lung cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: haemorrhage, neoplasm malignant, penile pain. BEVACIZUMAB dosage: 10 MG/KG, DAYS 1+15. During the same period patient was treated with ERLOTINIB, PEMETREXED, LIPITOR, FLOMAX, ENALAPRIL MALEATE, ACTOS, CLARITIN, ATENOLOL. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5295505-8
BEVACIZUMAB problem was reported by a Physician from BRAZIL on Mar 20, 2007. Male patient, 43 years of age, weighting 176.4 lb, was diagnosed with non-small cell lung cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: cardiac failure congestive, condition aggravated, dialysis, pneumonia, renal failure acute. BEVACIZUMAB dosage: 1185 MG, Q3W, INTRAVENOUS. During the same period patient was treated with VINORELBINE TARTRATE, LEVOTHYROXINE, CARDURAN, STARLIX, METFORMIN, AMITRIL. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5296017-8
Health Professional from UNITED STATES reported BEVACIZUMAB problem on Apr 09, 2007. Female patient, weighting 133.6 lb, was diagnosed with non-small cell lung cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: anaemia, constipation, nausea, vomiting. BEVACIZUMAB dosage: 15 MG/KG, Q3W. During the same period patient was treated with PEMETREXED, CARBOPLATIN. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5296107-X
BEVACIZUMAB problem was reported by a Health Professional from UNITED STATES on Apr 09, 2007. Female patient was diagnosed with non-small cell lung cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: anaemia, dizziness, fatigue. BEVACIZUMAB dosage: 15 MG/KG, Q3W. During the same period patient was treated with ERLOTINIB, REGLAN, PROCRIT. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5297507-4
Health Professional from UNITED STATES reported BEVACIZUMAB problem on Apr 09, 2007. Female patient, 61 years of age, weighting 116.8 lb, was diagnosed with non-small cell lung cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: hyperbilirubinaemia. BEVACIZUMAB dosage: 15 MG/KG, Q3W. During the same period patient was treated with GEMCITABINE, CARBOPLATIN, FENTANYL, MORPHINE SULPHATE, NEURONTIN, COMPAZINE, DULCOLAX. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5297519-0
BEVACIZUMAB problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 09, 2007. Female patient, 61 years of age, weighting 131.0 lb, was diagnosed with breast cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: chest pain, dyspnoea. BEVACIZUMAB dosage: 620 MG, Q2W. During the same period patient was treated with PACLITAXEL, ATIVAN, COMPAZINE, NEULASTA, ARANESP. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5297718-8
Consumer or non-health professional from UNITED STATES reported BEVACIZUMAB problem on Apr 12, 2007. Female patient, weighting 171.3 lb, was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: arthralgia, deep vein thrombosis, pain in extremity. BEVACIZUMAB dosage: 1185 MG. During the same period patient was treated with FLUOROURACIL, CAMPTOSAR, LEUCOVORIN CALCIUM, ARANESP, CRESTOR, DULCOLAX, DYAZIDE, GLYBURIDE. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5297725-5
BEVACIZUMAB problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Apr 03, 2007. Male patient, weighting 149.9 lb, was diagnosed with metastatic renal cell carcinoma and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: gliosis. BEVACIZUMAB dosage: 10 MG/KG, Q2W. During the same period patient was treated with INTERFERON ALPHA, PARACETAMOL, ATACAND, ZOMETA, MOVICOL. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5297826-1
Consumer or non-health professional from UNITED STATES reported BEVACIZUMAB problem on Apr 16, 2007. Male patient was diagnosed with glioblastoma multiforme and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: dehydration, disease progression, fall, hyponatraemia, nausea, pneumonia, somnolence, vomiting. BEVACIZUMAB dosage: 10 MG/KG. During the same period patient was treated with ERLOTINIB, TOPROL, PREVACID, RITALIN, KEPPRA, DECADRON, LOVASTATIN, COLACE. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5297830-3
BEVACIZUMAB problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 10, 2007. Male patient, weighting 145.0 lb, was diagnosed with non-small cell lung cancer, gastrooesophageal reflux disease, prophylaxis, anxiety, dysphagia, hypertension, upper respiratory tract infection and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: tracheitis. BEVACIZUMAB dosage: unknown. During the same period patient was treated with ERLOTINIB, NEXIUM, PLAVIX, LORAZEPAM, CARAFATE, LABETALOL, LEVAQUIN, ADVAIR DISKUS. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5297877-7
Consumer or non-health professional from UNITED STATES reported BEVACIZUMAB problem on Apr 13, 2007. Male patient, weighting 147.7 lb, was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: abdominal pain lower, abdominal pain upper, cancer pain, inadequate analgesia. BEVACIZUMAB dosage: 1303 MG. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM, ELOXATIN. Patient recovered.

Bevacizumab Side Effects Report #5298468-4
BEVACIZUMAB problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 09, 2007. Male patient, weighting 183.0 lb, was diagnosed with colorectal cancer metastatic, adrenal insufficiency, deep vein thrombosis and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: small intestinal obstruction. BEVACIZUMAB dosage: 465 MG, Q2W. During the same period patient was treated with CETUXIMAB, FLUOROURACIL, LEUCOVORIN CALCIUM, CORTISONE ACETATE, FLUDROCORTISONE ACETATE, COUMADIN. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5298665-8
Physician from UNITED STATES reported BEVACIZUMAB problem on Mar 27, 2007. Male patient, 68 years of age, weighting 160.7 lb, was diagnosed with non-small cell lung cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: cerebral ischaemia, fall, leukoencephalopathy. BEVACIZUMAB dosage: unknown. During the same period patient was treated with DOCETAXEL, CARBOPLATIN, LOVASTATIN, ATENOLOL, LISINOPRIL. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5299026-8
BEVACIZUMAB problem was reported by a Physician from UNITED STATES on Apr 11, 2007. Female patient, weighting 119.0 lb, was diagnosed with gallbladder cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: acute myocardial infarction, aortic arteriosclerosis, culture urine positive, mitral valve incompetence, sepsis. BEVACIZUMAB dosage: 10 MG, 2/MONTH. During the same period patient was treated with GEMCITABINE, OXALIPLATIN. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5299204-8
Consumer or non-health professional from UNITED STATES reported BEVACIZUMAB problem on Apr 11, 2007. Male patient, weighting 152.1 lb, was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: hyperhidrosis, pain. BEVACIZUMAB dosage: 350 MG. During the same period patient was treated with ELOXATIN, FLUOROURACIL, LEUCOVORIN CALCIUM. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5299258-9
BEVACIZUMAB problem was reported by a Physician from UNITED STATES on Apr 09, 2007. Male patient, weighting 160.8 lb, was diagnosed with non-small cell lung cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: cerebral arteriosclerosis. BEVACIZUMAB dosage: unknown. During the same period patient was treated with DOCETAXEL, CARBOPLATIN, LOVASTATIN, ATENOLOL, LISINOPRIL, ASPIRIN, NITROSTAT, LANTUS. Patient was hospitalized. Patient died on 03/09/2007.

Bevacizumab Side Effects Report #5299344-3
Physician from UNITED STATES reported BEVACIZUMAB problem on Apr 11, 2007. Female patient, 45 years of age, weighting 136.5 lb, was diagnosed with nasal septum perforation and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: epistaxis, nasal septum perforation, rhinorrhoea. BEVACIZUMAB dosage: 10 MG/KG Q 2 WEEKS IV. Patient recovered.

Bevacizumab Side Effects Report #5299487-4
BEVACIZUMAB problem was reported by a Physician from UNITED STATES on Apr 16, 2007. Female patient, weighting 121.3 lb, was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: dehydration, disease progression. BEVACIZUMAB dosage: unknown. During the same period patient was treated with DOCETAXEL, OXALIPLATIN. Patient died on 01/21/2007.

Bevacizumab Side Effects Report #5299706-4
Consumer or non-health professional from UNITED STATES reported BEVACIZUMAB problem on Apr 06, 2007. Female patient was diagnosed with breast cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: dyspnoea, pleural effusion. BEVACIZUMAB dosage: 15 MG/M2, Q2W. During the same period patient was treated with ARIMIDEX, COLACE, MOTRIN IB, LEVOXYL. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5299717-9
BEVACIZUMAB problem was reported by a Physician from UNITED STATES on Apr 05, 2007. Male patient, 44 years of age, was diagnosed with gastric cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: lymphopenia. BEVACIZUMAB dosage: 5 MG/KG, Q2W. During the same period patient was treated with TAXOTERE, PROTONIX, AMBIEN, ALLEGRA, REMERON, ATIVAN. Patient recovered.

Bevacizumab Side Effects Report #5299742-8
Consumer or non-health professional from UNITED KINGDOM reported BEVACIZUMAB problem on Apr 02, 2007. Male patient, weighting 198.4 lb, was diagnosed with colon cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: pyrexia. BEVACIZUMAB dosage: 450 MG, Q2W. During the same period patient was treated with OXALIPLATIN, LEUCOVORIN CALCIUM, FLUOROURACIL, ZESTORETIC. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5300447-5
BEVACIZUMAB problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Apr 03, 2007. Female patient, weighting 203.9 lb, was diagnosed with colorectal cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: subileus. BEVACIZUMAB dosage: 440 MG, Q2W. During the same period patient was treated with CAPECITABINE, OXALIPLATIN. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5300552-3
Consumer or non-health professional from UNITED STATES reported BEVACIZUMAB problem on Apr 10, 2007. Male patient, weighting 142.0 lb, was diagnosed with colorectal cancer metastatic and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: diarrhoea, oedema peripheral, pleural effusion, vomiting. BEVACIZUMAB dosage: 330 MG, QOW. During the same period patient was treated with CETUXIMAB, FLUOROURACIL, LEUCOVORIN CALCIUM, FOSAMAX, ZOCOR, ENALAPRIL MALEATE, AMARYL. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5300634-6
BEVACIZUMAB problem was reported by a Physician from UNITED KINGDOM on Apr 03, 2007. Female patient, weighting 123.5 lb, was diagnosed with colorectal cancer metastatic and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: myocarditis. BEVACIZUMAB dosage: 420 MG, Q3W. During the same period patient was treated with MITOMYCIN, XELODA, LOPERAMIDE, LIDOCAINE, NYSTATIN, PYRIDOXINE. Patient died on 09/01/2006.

Bevacizumab Side Effects Report #5300706-6
Consumer or non-health professional from UNITED STATES reported BEVACIZUMAB problem on Apr 16, 2007. Female patient, weighting 236.6 lb, was diagnosed with non-small cell lung cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: pulmonary haemorrhage. BEVACIZUMAB dosage: 1620 MG, Q3W. During the same period patient was treated with CARBOPLATIN, TAXOL, ALLOPURINOL, SYNTHROID, WELLBUTRIN, ALBUTEROL, LORTAB, FERROUS GLUCONATE. Patient died on 08/16/2006.

Bevacizumab Side Effects Report #5300753-4
BEVACIZUMAB problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 16, 2007. Male patient, weighting 184.5 lb, was diagnosed with non-small cell lung cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: lung infiltration. BEVACIZUMAB dosage: 15 MG/KG, Q3W. During the same period patient was treated with CARBOPLATIN, PEMETREXED, METOPROLOL SUCCINATE, LIPITOR, NEURONTIN, NORVASC, NEXIUM, DARVOCET. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5300772-8
Physician from UNITED KINGDOM reported BEVACIZUMAB problem on Apr 16, 2007. Female patient, weighting 195.1 lb, was diagnosed with breast cancer and was treated with BEVACIZUMAB. BEVACIZUMAB dosage: 7.5 MG/KG, Q3W. During the same period patient was treated with DOCETAXEL, TYLENOL, METOPROLOL SUCCINATE, ALLOPURINOL, DECADRON, METFORMIN, ARANESP, PAMIDRONATE DI. Patient died on 11/02/2006.

Bevacizumab Side Effects Report #5300838-2
BEVACIZUMAB problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 17, 2007. Male patient, 75 years of age, weighting 196.2 lb, was diagnosed with non-small cell lung cancer, bone marrow failure and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: asthenia, cough, decubitus ulcer, deep vein thrombosis, diarrhoea, haemoglobin decreased, hyperhidrosis, lung infiltration, oxygen saturation decreased. BEVACIZUMAB dosage: 15 MG/KG, Q3W. During the same period patient was treated with TAXOTERE, OXALIPLATIN, DILAUDID, FILGRASTIM, DURAGESIC, TUSSINEX, PHENERGAN, HYCODAN. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5300938-7
Physician from UNITED KINGDOM reported BEVACIZUMAB problem on Apr 17, 2007. Female patient, weighting 114.2 lb, was diagnosed with colorectal cancer metastatic and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: dehydration, pyrexia. BEVACIZUMAB dosage: 400 MG, Q3W. During the same period patient was treated with CAPECITABINE, OXALIPLATIN, MOTILIUM, ZOTON, BETALOC, CENTYL K. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5301453-7
BEVACIZUMAB problem was reported by a Health Professional from UNITED STATES on Apr 12, 2007. Male patient, 59 years of age, was diagnosed with non-small cell lung cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: dehydration, oesophageal pain, performance status decreased. BEVACIZUMAB dosage: 15 MG/KG, Q3W. During the same period patient was treated with ERLOTINIB. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5301509-9
Physician from UNITED STATES reported BEVACIZUMAB problem on Apr 17, 2007. Female patient was diagnosed with non-small cell lung cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: abdominal pain, nausea, pneumonia, sepsis. BEVACIZUMAB dosage: 15 MG/KG, Q3W. During the same period patient was treated with DOCETAXEL, OXALIPLATIN, SINGULAIR, DEXAMETHASONE, FLUCONAZOLE, ATIVAN, LISINOPRIL, COMPAZINE. Patient was hospitalized. Patient died on 02/08/2007.

Bevacizumab Side Effects Report #5301514-2
BEVACIZUMAB problem was reported by a Physician from UNITED STATES on Apr 10, 2007. Female patient, 43 years of age, was diagnosed with breast cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: myalgia. BEVACIZUMAB dosage: 818 MG, UNK. During the same period patient was treated with TAXOL, DOXORUBICIN, CYCLOPHOSPHAMIDE, NEULASTA, MEDROL. Patient was hospitalized. Patient recovered.

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Drug Information: Bevacizumab Injection

URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a607001.html

(be va siz' yoo mab)

IMPORTANT WARNING:

Bevacizumab may cause you to develop a hole in the wall of your stomach or intestine. This is a serious and possibly life-threatening condition. If you experience any of the following symptoms, call your doctor immediately: stomach pain, constipation, nausea, vomiting, or fever.Bevacizumab may slow the healing of wounds, such as cuts made by a doctor during surgery. In some cases, bevacizumab may cause a wound that has closed to split open. This is a serious and possibly life-threatening condition. If you experience this problem, call your doctor immediately. Tell your doctor if you have recently had surgery or if you plan to have surgery. If you have recently had surgery, you should not use bevacizumab until at least 28 days have passed and until the area has completed healed. If you are scheduled to have surgery, your doctor will stop your treatment with bevacizumab at least several weeks before the surgery.Bevacizumab may cause severe, life-threatening bleeding in the lungs of people who are using bevacizumab along with chemotherapy to treat lung cancer. Tell your doctor if you have recently coughed up blood or if you cough up blood at any time during your treatment.Talk to your doctor about the risks of using bevacizumab.

Why is this medication prescribed?

Bevacizumab is used with chemotherapy to treat cancer of the colon (large intestine) or rectum that has spread to other parts of the body. Bevacizumab is also used with chemotherapy to treat certain types of lung cancer. Bevacizumab is in a class of medications called antiangiogenic agents. It works by stopping the formation of blood vessels that bring oxygen and nutrients to tumors. This may slow the growth and spread of tumors.

How should this medicine be used?

Bevacizumab comes as a solution to administer slowly into a vein. Bevacizumab is administered by a doctor or nurse in a medical office, infusion center, or hospital. Bevacizumab is usually given once every 2 weeks to treat cancer of the colon or rectum and once every 3 weeks to treat lung cancer.

It should take 90 minutes for you to receive your first dose of bevacizumab. A doctor or nurse will watch you closely to see how your body reacts to bevacizumab. If you do not have any serious problems when you receive your first dose of bevacizumab, it will usually take 30 to 60 minutes for you to receive each of your remaining doses of the medication.

Other uses for this medicine

Bevacizumab is also sometimes used to treat wet age-related macular degeneration (AMD; an ongoing disease of the eye that causes loss of the ability to see straight ahead and may make it more difficult to read, drive, or perform other daily activities) and other types of cancer. Talk to your doctor about the risks of using bevacizumab to treat your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before receiving bevacizumab,

  • tell your doctor and pharmacist if you are allergic to bevacizumab or any other medications.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention anticoagulants (blood thinners) such as warfarin (Coumadin) and irinotecan (Camptosar). Also tell your doctor if you are taking or if you have ever taken an anthracycline (a type of chemotherapy used for breast cancer and some types of leukemia) such as daunorubicin (Cerubidine), doxorubicin (Adriamycin, Rubex), epirubicin (Ellence), or idarubicin (Idamycin). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have ever been treated with radiation therapy to the left side of your chest, and if you have or have ever had cancer that spread to your brain or spine, high blood pressure, or any condition that affects your heart or blood vessels (tubes that move blood between the heart and other parts of the body).
  • tell your doctor if you are pregnant or plan to become pregnant. Bevacizumab may harm the fetus and increase the risk of a pregnancy loss. You should use birth control to prevent pregnancy during your treatment with bevacizumab and for some time after you stop using the medication. If you become pregnant while using bevacizumab, call your doctor.
  • tell your doctor if you are breast-feeding. You should not breastfeed during your treatment with bevacizumab and for some time after you stop using the medication.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

If you miss an appointment to receive a dose of bevacizumab, call your doctor as soon as possible.

What side effects can this medication cause?

Bevacizumab may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • dizziness
  • fainting
  • nosebleeds
  • bleeding gums
  • weakness
  • loss of appetite
  • heartburn
  • change in ability to taste food
  • diarrhea
  • weight loss
  • dry mouth
  • sores on the skin or in the mouth
  • voice changes

Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately:

  • nosebleeds that cause dizziness or fainting or that do not stop after 10 to 15 minutes
  • unusual bruising or bleeding
  • black or bloody stools
  • bright red blood in stools
  • vomit that is bloody or looks like coffee grounds
  • coughing, gagging, or choking after eating or drinking
  • severe vaginal bleeding
  • headache
  • neck pain
  • slow or difficult speech
  • dizziness or faintness
  • weakness or numbness of an arm or leg
  • chest pain
  • pain in the arms, neck, or upper back
  • shortness of breath
  • seizures
  • extreme tiredness
  • confusion
  • change in vision or loss of vision
  • sore throat, fever, chills, and other signs of infection
  • swelling of the face, eyes, stomach, hands, feet, ankles, or lower legs
  • unexplained weight gain
  • foamy urine
  • dry, hacking cough
  • pain, tenderness, warmth, redness, or swelling in one leg only
  • redness, itching, or scaling of the skin

Bevacizumab may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.

What storage conditions are needed for this medicine?

Bevacizumab will be stored in the medical office, infusion center, or hospital.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:

  • headache

What other information should I know?

Keep all appointments with your doctor. Your doctor will check your blood pressure and test your urine regularly during your treatment with bevacizumab.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand name(s):

  • Avastin®

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