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Anxiety (3)
Palpitations (3)
Red Rash (3)
Tachycardia (3)
Upset Stomach (2)
Bleeding Nose (1)
Constantly Pooing (1)
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Bisolvon Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Platelet Count Decreased, Thrombotic Thrombocytopenic Purpura, Urticaria (8247086-4)
on Mar 16, 2012 Male from JAPAN , weighting 143.3 lb, was diagnosed with
  • productive cough
  • procedural pain
and was treated with Bisolvon. Directly after, patient experienced the unwanted or unexpected Bisolvon side effects: platelet count decreased, thrombotic thrombocytopenic purpura, urticaria. Bisolvon dosage: N/A.
Associated medications used:
  • Loxoprofen Sodium
  • Marzulene
  • Unasyn
  • Tamiflu
Patient was hospitalized.

Myocardial Infarction, Nausea, Chest Pain (8209793-9)
Patient was taking Bisolvon. Patient felt the following Bisolvon side effects: myocardial infarction, nausea, chest pain on Mar 13, 2012 from JAPAN Additional patient health information: Male , 82 years of age, . Bisolvon dosage: 12 Mg, Daily.
Multiple prescriptions taken:
  • Varenicline Tartrate (2 Mg, Daily)
  • Allegra (120 Mg, Daily)
  • Candesartan Cilexetil (8 Mg, Daily)
  • Norvasc (5 Mg,daily)
  • Varenicline Tartrate (Unk)


Pneumonia, Asthma (8183547-4)
Adverse event was reported on Feb 24, 2012 by a Female taking Bisolvon (Dosage: N/A) was diagnosed with
  • asthma
  • hypovitaminosis
and. Location: JAPAN , 98 years of age, weighting 92.59 lb, After Bisolvon was administered, patient encountered several Bisolvon side effects: pneumonia, asthma.
Multiple concurrent drugs taken:
  • Flavitan
  • Symbicort
  • Famotidine
  • Singulair
  • Alosenn
  • Hokunalin:tape
  • Levothyroxine Sodium (25/50 Mcg Alternate Day Dosing)
Patient was hospitalized.

Musculoskeletal Stiffness, Pyrexia (8143879-2)
on Feb 09, 2012 Male from JAPAN , 20 years of age, weighting 104.7 lb, was diagnosed with
  • prophylaxis
and was treated with Bisolvon. Directly after, patient experienced the unwanted or unexpected Bisolvon side effects: musculoskeletal stiffness, pyrexia. Bisolvon dosage: Daily Dose:3df.
Associated medications used:
  • Zonisamide
  • Mucosolvan (Daily Dose:3df)
  • Urso 250 (Daily Dose: 300mg)
  • Keppra
  • Lac-b (Daily Dose:3g)
  • Zonisamide
  • Epirenat (Daily Dose : 27ml)
  • Baclofen (Daily Dose:30mg)



Abnormal Behaviour (8141446-8)
on Feb 08, 2012 Female from JAPAN , 83 years of age, was treated with Bisolvon. Patient felt the following Bisolvon side effects: abnormal behaviour. Bisolvon dosage: Dosage Is Uncertain..
Multiple prescriptions taken:
  • Acetaminophen (Dosage Is Uncertain.)
  • Tamiflu (Dosage Is Uncertain.)
  • Periactin (Dosage Is Uncertain.)


Cardiac Failure, Hepatic Enzyme Increased, Pneumonia Aspiration (7812443-4)
Patient was taking Bisolvon. After Bisolvon was administered, patient encountered several Bisolvon side effects: cardiac failure, hepatic enzyme increased, pneumonia aspiration on Oct 04, 2011 from JAPAN Additional patient health information: Female , 69 years of age, weighting 85.98 lb, was diagnosed with
  • bronchitis
  • pneumonia
and. Bisolvon dosage: 2 Df, 2x/day.
Multiple concurrent drugs taken:
  • Zosyn
  • Unasyn (1.5 G, 2x/day)
  • Strong Neo-minophagen C (2 Df, 1x/day)
  • Zosyn (4.5 G, 2x/day)
  • Intrafat (1v, 1x/day)
  • Humulin R (14 Units, 1x/day)
  • Tathion (1 Df, 1x/day)
  • Tpn Electrolytes In Plastic Container (500 Ml, 2x/day)


Pyrexia, Skin Plaque, Pneumonia, Skin Erosion, Lip Erosion, Skin Lesion, Toxic Epidermal Necrolysis, Erythema Multiforme, Retinal Haemorrhage (7802482-1)
Adverse event was reported on Sep 28, 2011 by a Male taking Bisolvon (Dosage: 4ml Per Day) . Location: JAPAN , 45 years of age, weighting 176.4 lb, Directly after, patient experienced the unwanted or unexpected Bisolvon side effects: pyrexia, skin plaque, pneumonia, skin erosion, lip erosion, skin lesion, toxic epidermal necrolysis, erythema multiforme, retinal haemorrhage.
Associated medications used:
  • Vitaject (1iuax Per Day)
  • Elemenmic (1iuax Per Day)
  • Meropenem (.5g Per Day)
  • Cefazolin (1g Per Day)
  • Piperacillin Sodium (2g Per Day)
  • Piperacillin Sodium (4g Per Day)
  • Coniel (4mg Per Day)
  • Nafamostat Mesilate (300mg Per Day)


Anaphylactic Reaction (7795665-0)
on Sep 28, 2011 Female from JAPAN , 21 years of age, was diagnosed with
  • asthma
and was treated with Bisolvon. Patient felt the following Bisolvon side effects: anaphylactic reaction. Bisolvon dosage: N/A.
Multiple prescriptions taken:
  • Ventolin (.5ml Per Day)


Dyskinesia (7557084-1)
on Jun 16, 2011 Female from JAPAN , 68 years of age, was treated with Bisolvon. After Bisolvon was administered, patient encountered several Bisolvon side effects: dyskinesia. Bisolvon dosage: 8mg, Daily.
Multiple concurrent drugs taken:
  • Levothyroxine Sodium (50ug, Daily)
  • Levothyroxine Sodium (25ug, Daily)
  • Empynase (36000iu, Daily)
  • Zoloft (25 Mg, Daily)
  • Artane (4 Mg, 2x/day)


Dyskinesia (7551316-1)
Patient was taking Bisolvon. Directly after, patient experienced the unwanted or unexpected Bisolvon side effects: dyskinesia on Jun 14, 2011 from JAPAN Additional patient health information: Female , 68 years of age, . Bisolvon dosage: Unk.
Associated medications used:
  • Artane (8 Mg, Daily)
  • Empynase (Unk)
  • Zoloft (25 Mg, Daily)


Cardiac Failure, Hyperkalaemia (7316465-1)
Adverse event was reported on Feb 18, 2011 by a Female taking Bisolvon (Dosage: 4 Mg, 3x/day) was diagnosed with
  • upper respiratory tract inflammation
  • nephrogenic anaemia
  • insomnia
and. Location: JAPAN , 83 years of age, weighting 81.57 lb, Patient felt the following Bisolvon side effects: cardiac failure, hyperkalaemia.
Multiple prescriptions taken:
  • Ferrous Citrate (50 Mg, 2x/day)
  • Myslee (10 Mg, 1x/day)
  • Zithromax (500 Mg, 1x/day)
  • Lasix (40 Mg, 2x/day)
  • Toughmac E (1 Df, 3x/day)
  • Medicon (15 Mg, 3x/day)
  • Aldactone (12.5 Mg, 1x/day)
  • Flomax (100 Mg, 3x/day)
Patient was hospitalized.

Toxic Skin Eruption (6771167-5)
on Jun 15, 2010 Female from , 37 years of age, was diagnosed with
  • nasopharyngitis
  • allergy test
and was treated with Bisolvon Compositum. After Bisolvon was administered, patient encountered several Bisolvon side effects: toxic skin eruption. Bisolvon Compositum dosage: N/A.
Multiple concurrent drugs taken:
  • Codeine Sulfate (15 Mg)


Toxic Skin Eruption (6769414-9)
on Jun 10, 2010 Female from , 37 years of age, was diagnosed with
  • nasopharyngitis
  • allergy test
and was treated with Bisolvon Compositum. Directly after, patient experienced the unwanted or unexpected Bisolvon side effects: toxic skin eruption. Bisolvon Compositum dosage: N/A.
Associated medications used:
  • Codeine (15 Mg)


Eyelid Oedema, Lip Oedema, Pruritus (6469491-9)
Patient was taking Bisolvon Compositum. Patient felt the following Bisolvon side effects: eyelid oedema, lip oedema, pruritus on Dec 03, 2009 from Additional patient health information: Female , 37 years of age, was diagnosed with
  • nasopharyngitis
  • allergy test
and. Bisolvon Compositum dosage: Bromhexine Hydrochloride 7.5 Mg, Diphenhydramine Hydrochloride 22.5 Mg, Ephedrine Hydrochloride 22..
Multiple prescriptions taken:
  • Codeine (15 Mg)


Bisolvon Health Episodes

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Bisolvon Information

More About Bisolvon

Side Effects reported to FDA: 14. View Bisolvon Adverse Reports

Bisolvon safety alerts: No

Reported deaths: 3

Reported hospitalizations: 3

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