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Community-reported Briplatin side effects:

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Review Briplatin Safety Reports submitted to FDA

Total Briplatin reports: 33.
Briplatin FDA safety alerts: No.
Reported deaths: 14    Reported hospitalizations: 11.
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FDA Reported Briplatin Side Effects: myelodysplastic syndrome, diarrhoea, acute myeloid leukaemia, interstitial lung disease, haemoglobin decreased, pharyngeal stenosis, laryngeal stenosis, gastric ulcer, sepsis, immunodeficiency, platelet count decreased.
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Briplatin Side Effects Report #5198414-8
Physician from JAPAN reported BRIPLATIN problem on Dec 28, 2006. Female patient, 63 years of age, was diagnosed with non-small cell lung cancer and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: disseminated intravascular coagulation, platelet count decreased, pneumonia, renal impairment, subarachnoid haemorrhage, white blood cell count decreased. BRIPLATIN dosage: unknown. During the same period patient was treated with NAVELBINE. Patient died on 10/30/2006.

Briplatin Side Effects Report #5237277-9
BRIPLATIN problem was reported by a Physician from JAPAN on Feb 07, 2007. Male patient, 63 years of age, was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: disseminated intravascular coagulation, platelet count decreased, pneumonia, renal impairment, subarachnoid haemorrhage, white blood cell count decreased. BRIPLATIN dosage: unknown. During the same period patient was treated with NAVELBINE. Patient died on 10/30/2006.

Briplatin Side Effects Report #5245444-3
Health Professional from JAPAN reported BRIPLATIN problem on Feb 13, 2007. Male patient, 72 years of age, was diagnosed with salivary gland cancer and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: colitis ischaemic. BRIPLATIN dosage: unknown. During the same period patient was treated with TAXOTERE, THIOSULPHATE, DECADRON. Patient was hospitalized. Patient recovered.

Briplatin Side Effects Report #5313446-4
BRIPLATIN problem was reported by a Health Professional from JAPAN on Apr 13, 2007. Female patient, 33 years of age, was diagnosed with ovarian germ cell endodermal sinus tumour stage i and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: coagulopathy, fibrinolysis, foetal growth retardation, hepatic neoplasm, hypertension, normal newborn, oligohydramnios, peritoneal neoplasm, pregnancy. BRIPLATIN dosage: unknown. During the same period patient was treated with BLEOMYCIN SULPHATE, VINBLASTINE SULPHATE. Patient recovered.

Briplatin Side Effects Report #5313517-2
Health Professional from JAPAN reported BRIPLATIN problem on Apr 13, 2007. Male patient, 30 years of age, was diagnosed with lung adenocarcinoma and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: diarrhoea, disseminated intravascular coagulation, gastrointestinal oedema, neutropenic colitis, neutrophil count decreased, platelet count decreased. BRIPLATIN dosage: 1ST COURSE ON 16APR02 (80 MG.M2). During the same period patient was treated with NAVELBINE, GASTER, ALLOID, MAGNESIUM OXIDE, MS CONTIN. Patient was hospitalized. Patient recovered.

Briplatin Side Effects Report #5367789-9
BRIPLATIN problem was reported by a Health Professional from JAPAN on June 20, 2007. Female patient, 49 years of age, was diagnosed with ovarian cancer and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: myelodysplastic syndrome. BRIPLATIN dosage: unknown. During the same period patient was treated with VEPESID, ADRIAMYCIN PFS, ENDOXAN, IRINOTECAN. Patient died.

Briplatin Side Effects Report #5367794-2
Health Professional from JAPAN reported BRIPLATIN problem on June 20, 2007. Female patient, 64 years of age, was diagnosed with uterine cancer and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: immunodeficiency, myelodysplastic syndrome, sepsis. BRIPLATIN dosage: unknown. During the same period patient was treated with ADRIAMYCIN PFS. Patient died.

Briplatin Side Effects Report #5064833-3
BRIPLATIN problem was reported by a Physician from JAPAN on July 19, 2006. Male patient, 64 years of age, was diagnosed with hypopharyngeal cancer and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: laryngeal stenosis, pharyngeal stenosis. BRIPLATIN dosage: unknown. During the same period patient was treated with RANDA, FLUOROPLEX. Patient recovered.

Briplatin Side Effects Report #5064835-7
Physician from JAPAN reported BRIPLATIN problem on July 19, 2006. Male patient, 60 years of age, was diagnosed with hypopharyngeal cancer and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: laryngeal stenosis, pharyngeal stenosis. BRIPLATIN dosage: unknown. During the same period patient was treated with RANDA, FLUOROPLEX. Patient recovered.

Briplatin Side Effects Report #5064838-2
BRIPLATIN problem was reported by a Physician from JAPAN on July 19, 2006. Female patient, 53 years of age, was diagnosed with laryngeal cancer and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: laryngeal stenosis, pharyngeal stenosis. BRIPLATIN dosage: unknown. During the same period patient was treated with RANDA, FLUOROURACIL. Patient recovered.

Briplatin Side Effects Report #5081855-7
Physician from JAPAN reported BRIPLATIN problem on July 19, 2006. Male patient, 64 years of age, was diagnosed with hypopharyngeal cancer and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: laryngeal stenosis, pharyngeal stenosis. BRIPLATIN dosage: unknown. During the same period patient was treated with RANDA, FLUOROURACIL. Patient recovered.

Briplatin Side Effects Report #5098366-5
BRIPLATIN problem was reported by a Physician from JAPAN on Nov 11, 2003. Female patient, 62 years of age, was diagnosed with gastric cancer and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: gastrointestinal haemorrhage, haemoglobin decreased. BRIPLATIN dosage: unknown. Patient was hospitalized. Patient recovered.

Briplatin Side Effects Report #5098677-3
Physician from JAPAN reported BRIPLATIN problem on Aug 28, 2006. Female patient, 67 years of age, was diagnosed with gastric cancer and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: diarrhoea, haemoglobin decreased, haemorrhage, nausea. BRIPLATIN dosage: unknown. Patient was hospitalized. Patient recovered.

Briplatin Side Effects Report #5103421-7
BRIPLATIN problem was reported by a Physician from JAPAN on Sept 07, 2006. Male patient, 67 years of age, was diagnosed with lung adenocarcinoma and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: interstitial lung disease. BRIPLATIN dosage: unknown. During the same period patient was treated with IRINOTECAN. Patient recovered.

Briplatin Side Effects Report #5121914-3
Health Professional from JAPAN reported BRIPLATIN problem on Sept 27, 2006. Female patient, 56 years of age, was diagnosed with ovarian cancer and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: acute myeloid leukaemia. BRIPLATIN dosage: unknown. During the same period patient was treated with TAXOL, VEPESID, PARAPLATIN, ENDOXAN, TAXOTERE, FARMORUBICIN. Patient recovered.

Briplatin Side Effects Report #5129813-8
BRIPLATIN problem was reported by a Physician from JAPAN on Nov 11, 2003. Female patient, 62 years of age, was diagnosed with gastric cancer and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: gastrointestinal haemorrhage, haemoglobin decreased. BRIPLATIN dosage: unknown. Patient was hospitalized. Patient recovered.

Briplatin Side Effects Report #5134149-5
Physician from JAPAN reported BRIPLATIN problem on Aug 28, 2006. Female patient, 67 years of age, was diagnosed with gastric cancer and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: abdominal pain, diarrhoea, haemoglobin decreased, haemorrhage, melaena, nausea. BRIPLATIN dosage: unknown. Patient was hospitalized. Patient recovered.

Briplatin Side Effects Report #5134182-3
BRIPLATIN problem was reported by a Health Professional from JAPAN on Sept 27, 2006. Female patient, 55 years of age, was diagnosed with ovarian cancer and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: acute myeloid leukaemia. BRIPLATIN dosage: unknown. During the same period patient was treated with TAXOL, VEPESID, PARAPLATIN, ENDOXAN, TAXOTERE, FARMORUBICIN. Patient died on 09/16/2005.

Briplatin Side Effects Report #5141463-6
Consumer or non-health professional from UNITED STATES reported BRIPLATIN problem on Sept 27, 2006. Female patient, 55 years of age, was diagnosed with ovarian cancer and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: acute myeloid leukaemia. BRIPLATIN dosage: unknown. During the same period patient was treated with TAXOL, VEPESID, PARAPLATIN, ENDOXAN, TAXOTERE, FARMORUBICIN. Patient died on 09/16/2005.

Briplatin Side Effects Report #5145073-6
BRIPLATIN problem was reported by a Physician from JAPAN on May 26, 2006. Male patient, 68 years of age, was diagnosed with gastric cancer and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: melaena, upper gastrointestinal haemorrhage. BRIPLATIN dosage: unknown. Patient was hospitalized. Patient recovered.

Briplatin Side Effects Report #5148941-4
Consumer or non-health professional from UNITED STATES reported BRIPLATIN problem on Sept 27, 2006. Female patient, 56 years of age, was diagnosed with ovarian cancer and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: acute myeloid leukaemia. BRIPLATIN dosage: unknown. During the same period patient was treated with TAXOL, VEPESID, PARAPLATIN, ENDOXAN, TAXOTERE, FARMORUBICIN. Patient died on 09/16/2005.

Briplatin Side Effects Report #5150608-3
BRIPLATIN problem was reported by a Physician from JAPAN on Nov 09, 2006. Male patient, 72 years of age, was diagnosed with hepatic neoplasm malignant and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: interstitial lung disease. BRIPLATIN dosage: unknown. During the same period patient was treated with FLUOROURACIL. Patient recovered.

Briplatin Side Effects Report #5168939-X
Physician from JAPAN reported BRIPLATIN problem on Nov 09, 2006. Male patient, 72 years of age, was diagnosed with hepatic neoplasm malignant and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: interstitial lung disease. BRIPLATIN dosage: unknown. During the same period patient was treated with FLUOROURACIL, GASTER D, VASOLAN, WARFARIN. Patient died on 11/10/2006.

Briplatin Side Effects Report #5393667-5
BRIPLATIN problem was reported by a Health Professional from JAPAN on July 18, 2007. Female patient, 58 years of age, was diagnosed with oesophageal carcinoma and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: oesophageal perforation. BRIPLATIN dosage: unknown. During the same period patient was treated with FLUOROURACIL. Patient died.

Briplatin Side Effects Report #5406128-1
Health Professional from JAPAN reported BRIPLATIN problem on Aug 02, 2007. Female patient, 58 years of age, was diagnosed with ovarian cancer and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: myelodysplastic syndrome. BRIPLATIN dosage: unknown. During the same period patient was treated with VEPESID, ENDOXAN, ADRIAMYCIN PFS, IRINOTECAN. Patient died on 04/02/2004.

Briplatin Side Effects Report #5406330-9
BRIPLATIN problem was reported by a Health Professional from JAPAN on Aug 02, 2007. Female patient, 69 years of age, was diagnosed with uterine cancer and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: immunodeficiency, myelodysplastic syndrome, sepsis. BRIPLATIN dosage: unknown. During the same period patient was treated with ADRIAMYCIN PFS. Patient was hospitalized. Patient died on 07/19/2006.

Briplatin Side Effects Report #5444322-4
Health Professional from JAPAN reported BRIPLATIN problem on Sept 04, 2007. Female patient, 64 years of age, was diagnosed with uterine cancer and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: immunodeficiency, myelodysplastic syndrome, sepsis. BRIPLATIN dosage: unknown. During the same period patient was treated with ADRIAMYCIN PFS. Patient was hospitalized. Patient died on 07/19/2006.

Briplatin Side Effects Report #5444861-6
BRIPLATIN problem was reported by a Health Professional from JAPAN on Sept 03, 2007. Female patient, 49 years of age, was diagnosed with ovarian cancer and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: malignant neoplasm progression, myelodysplastic syndrome. BRIPLATIN dosage: unknown. During the same period patient was treated with VEPESID, ENDOXAN, ADRIAMYCIN PFS, IRINOTECAN. Patient died on 04/02/2004.

Briplatin Side Effects Report #5447327-2
Physician from JAPAN reported BRIPLATIN problem on Sept 06, 2007. Male patient, 70 years of age, was diagnosed with pleural mesothelioma malignant and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: anorexia, gastric ulcer, rash. BRIPLATIN dosage: unknown. During the same period patient was treated with ALIMTA, PANVITAN, DECADRON. Patient recovered.

Briplatin Side Effects Report #5448580-1
BRIPLATIN problem was reported by a Health Professional from JAPAN on Sept 10, 2007. Male patient, 23 years of age, was diagnosed with medulloblastoma and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: renal failure acute, tumour lysis syndrome. BRIPLATIN dosage: unknown. During the same period patient was treated with ETOPOSIDE. Patient recovered.

Briplatin Side Effects Report #5453766-6
Health Professional from JAPAN reported BRIPLATIN problem on Sept 12, 2007. Female patient, 58 years of age, was diagnosed with hepatic mass and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: interstitial lung disease, malignant neoplasm progression, neoplasm recurrence. BRIPLATIN dosage: unknown. During the same period patient was treated with VEPESID, ADRIAMYCIN RDF, CYCLOPHOSPHAMIDE, VINCRISTINE SULPHATE, FLUOROURACIL. Patient died.

Briplatin Side Effects Report #5455347-7
BRIPLATIN problem was reported by a Health Professional from JAPAN on Sept 13, 2007. Female patient, 72 years of age, was diagnosed with pleural mesothelioma malignant and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: amyloidosis, aspartate aminotransferase increased, blood albumin decreased, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, decreased appetite, diarrhoea, febrile neutropenia, gastric ulcer. BRIPLATIN dosage: unknown. During the same period patient was treated with ALIMTA, PANVITAN, MECOBALAMIN, FERROMIA, URSO, FLOPROPIONE, TANNALBIN, ALFAROL. Patient was hospitalized. Patient recovered.

Briplatin Side Effects Report #5458658-4
Health Professional from JAPAN reported BRIPLATIN problem on Sept 13, 2007. Female patient, 72 years of age, was diagnosed with pleural mesothelioma malignant and was treated with BRIPLATIN. After drug was administered, patient experienced the following problems/side effects: amyloidosis, aspartate aminotransferase increased, blood albumin decreased, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, decreased appetite, diarrhoea, febrile neutropenia, gastric ulcer. BRIPLATIN dosage: unknown. During the same period patient was treated with ALIMTA, PANVITAN, MECOBALAMIN, FERROMIA, URSO, FLOPROPIONE, TANNALBIN, ALFAROL. Patient was hospitalized. Patient recovered.

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