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Bufferin Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 129 

Blood Pressure Increased, Oedema Peripheral, Prostatomegaly (8225549-5)
on Mar 12, 2012 Male from UNITED STATES , 82 years of age, was diagnosed with
  • cardiac disorder
and was treated with Bufferin. Directly after, patient experienced the unwanted or unexpected Bufferin side effects: blood pressure increased, oedema peripheral, prostatomegaly. Bufferin dosage: 1 Df, Qd.

Blood Pressure Increased, Syncope (8219830-3)
Patient was taking Bufferin. Patient felt the following Bufferin side effects: blood pressure increased, syncope on Mar 12, 2012 from UNITED STATES Additional patient health information: Male , 75 years of age, was diagnosed with
  • pain
and. Bufferin dosage: N/A. Patient was hospitalized.

Ocular Hyperaemia, Gait Disturbance, Reiter's Syndrome, Pyrexia, Arthralgia, Malaise, Decreased Appetite (8158420-8)
Adverse event was reported on Feb 16, 2012 by a Male taking Bufferin A81 (Dosage: Once A Day) . Location: JAPAN , weighting 152.1 lb, After Bufferin was administered, patient encountered several Bufferin side effects: ocular hyperaemia, gait disturbance, reiter's syndrome, pyrexia, arthralgia, malaise, decreased appetite.
Multiple concurrent drugs taken:
  • Alpharol (Once A Day)
  • Lansoprazole (Once A Day)
  • Precipitated Calcium Carbonate (Three Times A Day)
  • Biopress (Once A Day)
  • Norvasc (Once A Day)
  • Immucyst
  • Sevelamer Hydrochloride (Three Times A Day)
Patient was hospitalized.

Tremor, Exostosis, Atrial Flutter, Tinnitus, Cardiac Murmur (8154677-8)
on Feb 09, 2012 Female from UNITED STATES , 85 years of age, was diagnosed with
  • arthritis
and was treated with Bufferin. Directly after, patient experienced the unwanted or unexpected Bufferin side effects: tremor, exostosis, atrial flutter, tinnitus, cardiac murmur. Bufferin dosage: Unk.
Associated medications used:
  • Acetylsalicylic Acid Srt
  • Tramadol Hcl



Tachycardia (8133605-5)
on Feb 07, 2012 Female from BRAZIL , weighting 160.9 lb, was diagnosed with
  • thrombosis
and was treated with Bufferin. Patient felt the following Bufferin side effects: tachycardia. Bufferin dosage: 1 Df, Unk.

Abnormal Behaviour, Sedation, Feeling Drunk, Feeling Abnormal, Arthralgia (8094998-0)
Patient was taking Bufferin Extra Strength Tablets. After Bufferin was administered, patient encountered several Bufferin side effects: abnormal behaviour, sedation, feeling drunk, feeling abnormal, arthralgia on Jan 31, 2012 from UNITED STATES Additional patient health information: Male , 64 years of age, weighting 165.0 lb, was diagnosed with
  • arthritis
and. Bufferin Extra Strength Tablets dosage: 500mg.

Pneumonia Aspiration, Muscular Weakness (8087966-6)
Adverse event was reported on Jan 24, 2012 by a Male taking Bufferin (Dosage: N/A) was diagnosed with
  • myocardial infarction
  • rhinitis allergic
  • hypercholesterolaemia
and. Location: JAPAN , 87 years of age, weighting 114.6 lb, Directly after, patient experienced the unwanted or unexpected Bufferin side effects: pneumonia aspiration, muscular weakness.
Associated medications used:
  • Cetirizine Hcl
  • Crestor
Patient was hospitalized.

Blood Pressure Increased, Syncope (8065819-7)
on Jan 12, 2012 Male from UNITED STATES , 75 years of age, was treated with Bufferin. Patient felt the following Bufferin side effects: blood pressure increased, syncope. Bufferin dosage: 1 Df, Unk. Patient was hospitalized.

Carotid Artery Disease (8065814-8)
on Jan 12, 2012 Female from UNITED STATES , 85 years of age, was diagnosed with
  • rheumatoid arthritis
and was treated with Bufferin. After Bufferin was administered, patient encountered several Bufferin side effects: carotid artery disease. Bufferin dosage: 6 Df, Unk.

(8064416-7)
Patient was taking Bufferin. on Jan 10, 2012 from UNITED STATES Additional patient health information: Female , 94 years of age, . Bufferin dosage: N/A.

Tachycardia (8060555-5)
Adverse event was reported on Jan 12, 2012 by a Female taking Bufferin (Dosage: 1 Df, Unk) was diagnosed with
  • prophylaxis
and. Location: BRAZIL , weighting 160.9 lb, Patient felt the following Bufferin side effects: tachycardia.

(8050217-2)
on Jan 11, 2012 Female from UNITED STATES , 91 years of age, was diagnosed with
  • headache
and was treated with Bufferin. . Bufferin dosage: Unk.

Gastric Ulcer Haemorrhage (7958981-5)
on Nov 22, 2011 Male from JAPAN , 76 years of age, was diagnosed with
  • myalgia
and was treated with Bufferin. Directly after, patient experienced the unwanted or unexpected Bufferin side effects: gastric ulcer haemorrhage. Bufferin dosage: Daily Dose: 2 Df.
Associated medications used:
  • Menest (Daily Dose: 200 Mg)
  • Dops
  • Dops (Daily Dose: 400 Mg)
  • Ludiomil (Daily Dose: 30 Mg)
  • Amitriptyline Hcl (Daily Dose: 10 Mg)
  • Ubretid
  • Seirogan (Daily Dose: 3 Df)
  • Rotigotine
Patient was hospitalized.

Helicobacter Test Positive, Gastric Ulcer (7949883-9)
Patient was taking Bufferin. Patient felt the following Bufferin side effects: helicobacter test positive, gastric ulcer on Nov 29, 2011 from JAPAN Additional patient health information: Male , 73 years of age, . Bufferin dosage: Unk.
Multiple prescriptions taken:
  • Celecoxib (200 Mg/day)
  • Ludiomil
  • Methycobal
Patient was hospitalized.

Abdominal Pain Upper, Weight Decreased, Gastritis (7939408-6)
Adverse event was reported on Nov 18, 2011 by a Female taking Bufferin (Dosage: 1 Df/day (30 Ct)) was diagnosed with
  • coronary artery disease
and. Location: BRAZIL , 68 years of age, After Bufferin was administered, patient encountered several Bufferin side effects: abdominal pain upper, weight decreased, gastritis.

Respiratory Tract Infection (7939278-6)
on Nov 16, 2011 Female from UNITED STATES , 69 years of age, was diagnosed with
  • headache
and was treated with Bufferin. Directly after, patient experienced the unwanted or unexpected Bufferin side effects: respiratory tract infection. Bufferin dosage: 2 Df, Bid.

Encephalitis, Inappropriate Antidiuretic Hormone Secretion (7887979-0)
on Oct 27, 2011 Female from JAPAN , weighting 118.2 lb, was diagnosed with
  • scleroderma
and was treated with Bufferin. Patient felt the following Bufferin side effects: encephalitis, inappropriate antidiuretic hormone secretion. Bufferin dosage: 81 Mg, Uid/qd.
Multiple prescriptions taken:
  • Prograf (1 Mg, Uid/qd)
  • Onealfa (0.5 Ug, Uid/qd)
  • Selbex (50 Mg, Tid)
  • Ketoprofen (20 Mg, Uid/qd)
  • Coniel (4 Mg, Uid/qd)
  • Celecoxib (100 Mg, Bid)
  • Alendronate Sodium
  • Prednisolone (5 Mg, Uid/qd)
Patient was hospitalized.

Gastric Ulcer, Angina Pectoris, Chest Discomfort (7841479-2)
Patient was taking Bufferin. After Bufferin was administered, patient encountered several Bufferin side effects: gastric ulcer, angina pectoris, chest discomfort on Oct 17, 2011 from JAPAN Additional patient health information: Male , weighting 125.7 lb, . Bufferin dosage: N/A.
Multiple concurrent drugs taken:
  • Neo Vitacain
  • Neurotropin
  • Loxonin
  • Methycobal
  • Rabeprazole Sodium
  • Stick Zenol
  • Torsemide
  • Sennoside
Patient was hospitalized.

Blood Iron Decreased, Gastric Ulcer, Gastric Haemorrhage, Blood Uric Acid Increased (7813223-6)
Adverse event was reported on Oct 05, 2011 by a Male taking Bufferin Cardio (Dosage: N/A) . Location: BRAZIL , 61 years of age, Directly after, patient experienced the unwanted or unexpected Bufferin side effects: blood iron decreased, gastric ulcer, gastric haemorrhage, blood uric acid increased.
Associated medications used:
  • Atacand Hct (16/12.5 Mg)


Respiratory Tract Infection (7812873-0)
on Oct 03, 2011 Female from UNITED STATES , 69 years of age, was diagnosed with
  • headache
and was treated with Bufferin. Patient felt the following Bufferin side effects: respiratory tract infection. Bufferin dosage: 2 Df, Bid.

Cough, Thrombocytopenia, Neutropenia, Upper Gastrointestinal Haemorrhage, Pneumonia, Upper Respiratory Tract Inflammation, Prothrombin Time Prolonged, Platelet Count Decreased (7811011-8)
on Oct 05, 2011 Female from JAPAN , weighting 85.98 lb, was diagnosed with
  • angina pectoris
and was treated with Bufferin. After Bufferin was administered, patient encountered several Bufferin side effects: cough, thrombocytopenia, neutropenia, upper gastrointestinal haemorrhage, pneumonia, upper respiratory tract inflammation, prothrombin time prolonged, platelet count decreased. Bufferin dosage: 81 Milligram.
Multiple concurrent drugs taken:
  • Sigmart (10 Milligram)
  • Lenadex (40 Milligram)
  • Lenadex (20 Milligram)
  • Dexamethasone Sodium Phosphate (33 Milligram)
  • Warfarin Sodium (2 Milligram)
  • Revlimid (15 Milligram)
  • Lenadex (20 Milligram)
  • Nespo (30 Microgram)
Patient was hospitalized.

Gallbladder Cancer, Hyperkalaemia (7774026-4)
Patient was taking Bufferin. Directly after, patient experienced the unwanted or unexpected Bufferin side effects: gallbladder cancer, hyperkalaemia on Sep 22, 2011 from JAPAN Additional patient health information: Male , 95 years of age, was diagnosed with
  • arteriosclerosis obliterans
  • hypertension
and. Bufferin dosage: 81 Mg, 1x/day.
Associated medications used:
  • Eplerenone (50 Mg, 1x/day)
  • Candesartan Cilexetil (8 Mg, 1x/day)
  • Furosemide (20 Mg, 1x/day)
  • Eplerenone


Hiatus Hernia, Gastritis, Suture Rupture, Insomnia (7744056-7)
Adverse event was reported on Sep 02, 2011 by a Male taking Bufferin (Dosage: N/A) . Location: BRAZIL , 65 years of age, weighting 180.8 lb, Patient felt the following Bufferin side effects: hiatus hernia, gastritis, suture rupture, insomnia.
Multiple prescriptions taken:
  • Nexium
  • Nexium
  • Nexium
  • Pressat
  • Clopidogrel
  • Micardis
  • Nexium
  • Crestor
Patient was hospitalized.

Dementia Alzheimer's Type, Irritability (7735209-2)
on Aug 31, 2011 Male from BRAZIL , 85 years of age, was diagnosed with
  • cardiac disorder
  • blood pressure
  • irritability
  • infarction
and was treated with Bufferin. After Bufferin was administered, patient encountered several Bufferin side effects: dementia alzheimer's type, irritability. Bufferin dosage: 1 Df, Qd (after Lunch).
Multiple concurrent drugs taken:
  • Losartan Potassium (1 Df, Qd)
  • Citalopram (1 Df, Qd)
  • Propatylnitrate (2 Df, Qd)


Gastric Ulcer, Anaemia (7704046-7)
on Aug 17, 2011 Male from JAPAN , 73 years of age, was treated with Bufferin. Directly after, patient experienced the unwanted or unexpected Bufferin side effects: gastric ulcer, anaemia. Bufferin dosage: N/A.
Associated medications used:
  • Cytotec
  • Mobic
Patient was hospitalized.

Showing 1-25 of 129 

Bufferin Health Episodes

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Bufferin Information

Alternative BUFFERIN Names:ASPIRIN

Active Ingredient: ASPIRIN

More About Bufferin

Side Effects reported to FDA: 129. View Bufferin Adverse Reports

Bufferin safety alerts: No

Reported deaths: 11

Reported hospitalizations: 48

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