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1.5 million people annually are harmed from drug errors.
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From simple mix-ups to fatal overdoses, medication mistakes happen, on average, once a day to every hospital patient, a new report says. Nationwide, at least 1.5 million people annually are harmed from drug errors, more than half of them in nursing homes.
Many Unfavorable Drug Studies Aren’t Published. Nearly a third of antidepressant drug studies are never published in the medical literature, and nearly all of those happen to show that the drug being tests failed to work.
Only Drugs That are Safe Should be put on the Market. Drug developers are just beginning to come to grips with recent FDA oversight reforms and how they will affect drug safety. But, it appears that industry and consumer advocates are not together on how well the overhaul will be able to prevent future drug safety scandals.

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Review Busulphan Safety Reports submitted to FDA

Total Busulphan reports: 4.
Busulphan FDA safety alerts: No.
Reported deaths: 2    .
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FDA Reported Busulphan Side Effects: thrombocytopenia, gastrointestinal haemorrhage, leukaemia recurrent, cerebral toxoplasmosis, acute graft versus host disease in skin, neutropenic sepsis, multi-organ failure.
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Busulphan Side Effects Report #5241535-1
Consumer or non-health professional from AUSTRALIA reported BUSULPHAN problem on Feb 13, 2007. Female patient was diagnosed with mantle cell lymphoma and was treated with BUSULPHAN. After drug was administered, patient experienced the following problems/side effects: multi-organ failure, neutropenic sepsis. BUSULPHAN dosage: 1MGK SEE TEXT. During the same period patient was treated with MELPHALAN, FOLINIC ACID, TRIMETHOPRIM, RITUXIMAB, VINCRISTINE, DEXAMETHASONE, METHOTREXATE, CYCLOPHOSPHAMIDE. Patient died.

Busulphan Side Effects Report #5241538-7
BUSULPHAN problem was reported by a Consumer or non-health professional from AUSTRALIA on Feb 13, 2007. Female patient was diagnosed with mantle cell lymphoma and was treated with BUSULPHAN. After drug was administered, patient experienced the following problems/side effects: gastrointestinal haemorrhage, thrombocytopenia. BUSULPHAN dosage: 1MGK SEE TEXT. During the same period patient was treated with MELPHALAN, FOLINIC ACID, TRIMETHOPRIM, RITUXIMAB, VINCRISTINE, DEXAMETHASONE, METHOTREXATE, CYCLOPHOSPHAMIDE. Patient recovered.

Busulphan Side Effects Report #5244207-2
Consumer or non-health professional from UNITED KINGDOM reported BUSULPHAN problem on Feb 14, 2007. Male patient, 63 years of age, was diagnosed with graft versus host disease and was treated with BUSULPHAN. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, cerebral toxoplasmosis, leukaemia recurrent. BUSULPHAN dosage: unknown. During the same period patient was treated with CAMPATH, CYCLOSPORINE, FLUDARABINE, CYTARABINE, NEUPOGEN, IDARUBICIN, SULFAMETHOXAZOLE, TRIMETOPRIM. Patient died.

Busulphan Side Effects Report #5248725-2
BUSULPHAN problem was reported by a Consumer or non-health professional from AUSTRALIA on Feb 13, 2007. Female patient was diagnosed with mantle cell lymphoma, antibiotic prophylaxis and was treated with BUSULPHAN. After drug was administered, patient experienced the following problems/side effects: gastrointestinal haemorrhage, thrombocytopenia. BUSULPHAN dosage: 1 MG/KG/SEE TEXT/ORAL. During the same period patient was treated with TRIMETHOPRIM, VINCRISTINE, DEXAMETHASONE, METHOTREXATE, CYCLOPHOSPHAMIDE. Patient recovered.


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multi-organ failure, neutropenic sepsis gastrointestinal haemorrhage, thrombocytopenia acute graft versus host disease in skin, cerebral toxoplasmosis, leukaemia recurrent, was diagnosed with mantle cell lymphoma and was diagnosed with mantle cell lymphoma and was diagnosed with graft versus host disease and