Capecitabine Safety Reports submitted to FDA

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Total Capecitabine reports: 757.
Capecitabine FDA safety alerts: 2001 .
Reported deaths: 196 Reported hospitalizations: 611.
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FDA Reported Capecitabine Side Effects: diarrhoea, vomiting, dehydration, nausea, mucosal inflammation, pyrexia, febrile neutropenia, asthenia, septic shock, anaemia, renal failure acute.
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Capecitabine Side Effects Report #5317074-6
Physician from UNITED KINGDOM reported CAPECITABINE problem on Apr 24, 2007. Male patient, 69 years of age, weighting 158.7 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: bronchopneumonia, cerebral haemorrhage, dyspnoea. CAPECITABINE dosage: unknown. During the same period patient was treated with CISPLATIN. Patient was hospitalized. Patient died on 12/28/2006.

Capecitabine Side Effects Report #5318014-6
CAPECITABINE problem was reported by a Physician from NETHERLANDS on Apr 26, 2007. Male patient, 58 years of age, was diagnosed with colorectal cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: dehydration, diarrhoea, fistula, hypokalaemia, infusion related reaction. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, OXALIPLATIN, LOPERAMIDE. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5318025-0
Health Professional from UNITED STATES reported CAPECITABINE problem on Apr 26, 2007. Female patient, 62 years of age, weighting 89.95 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: dehydration, diarrhoea, hyponatraemia, pancreatitis. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, PERCODAN, DECADRON. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5318026-2
CAPECITABINE problem was reported by a Physician from UNITED STATES on Apr 27, 2007. Female patient, 62 years of age, weighting 140.0 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: hepatic cirrhosis. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, ABRAXANE, DOCETAXEL. Patient recovered.

Capecitabine Side Effects Report #5318029-8
Physician from UNITED KINGDOM reported CAPECITABINE problem on Apr 27, 2007. Female patient, 62 years of age, weighting 158.7 lb, was diagnosed with colon cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: cardiospasm. CAPECITABINE dosage: 2000 MG IN THE MORNING AND 2500 MG IN THE EVENING FOR 14 DAYS OF 21 DAY CYCLE (2500 MG/M2 DAILY DAY+. During the same period patient was treated with BEVACIZUMAB, GAVISCON. Patient recovered.

Capecitabine Side Effects Report #5318031-6
CAPECITABINE problem was reported by a Physician from UNITED KINGDOM on Apr 23, 2007. Female patient, 46 years of age, weighting 167.6 lb, was diagnosed with breast cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: cough, lower respiratory tract infection, pyrexia. CAPECITABINE dosage: unknown. During the same period patient was treated with EPIRUBICIN. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5320398-X
Physician from NETHERLANDS reported CAPECITABINE problem on Apr 13, 2007. Male patient, 33 years of age, was diagnosed with colorectal cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: ill-defined disorder, perianal abscess. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, OXALIPLATIN, SERESTA, LOSEC, PARACETAMOL, MOVICOLON, OXYCONTIN. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5320443-1
CAPECITABINE problem was reported by a Physician from UNITED STATES on May 04, 2007. Male patient, weighting 151.0 lb, was diagnosed with gastric cancer, hypertension, hypercholesterolaemia, gastric disorder and was treated with CAPECITABINE. CAPECITABINE dosage: unknown. During the same period patient was treated with DOCETAXEL, OXALIPLATIN, PERINDOPRIL, SIMVASTATIN, LANSOPRAZOLE. Patient died on 05/02/2007.

Capecitabine Side Effects Report #5322203-4
Physician from AUSTRALIA reported CAPECITABINE problem on May 01, 2007. Male patient, 83 years of age, weighting 174.2 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: leukoencephalopathy, splenic infarction. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB. Patient recovered.

Capecitabine Side Effects Report #5322204-6
CAPECITABINE problem was reported by a Physician from SWITZERLAND on May 04, 2007. Male patient, 66 years of age, was diagnosed with colorectal cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: hypokalaemia, meniere's disease, vomiting. CAPECITABINE dosage: unknown. During the same period patient was treated with OXALIPLATIN, IRINOTECAN, GLICLAZIDUM, ACIDUM ACETYLSALICYLICUM, CANDESARTANUM, LEVOTHYROXINUM NATRICUM, ZOLPIDEM. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5322209-5
Physician from CANADA reported CAPECITABINE problem on Apr 30, 2007. Male patient, 40 years of age, weighting 121.3 lb, was diagnosed with colorectal cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: intestinal obstruction. CAPECITABINE dosage: unknown. During the same period patient was treated with ERLOTINIB. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5322614-7
CAPECITABINE problem was reported by a Health Professional from on May 08, 2007. Male patient, weighting 200.0 lb, was diagnosed with oesophageal carcinoma and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: respiratory failure, staphylococcal infection. CAPECITABINE dosage: unknown. During the same period patient was treated with DOCETAXEL, OXALIPLATIN. Patient died on 09/11/2006.

Capecitabine Side Effects Report #5323674-X
Physician from UNITED KINGDOM reported CAPECITABINE problem on May 04, 2007. Female patient, 62 years of age, weighting 136.7 lb, was diagnosed with breast cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased. CAPECITABINE dosage: unknown. During the same period patient was treated with EPIRUBICIN, NEULASTA. Patient recovered.

Capecitabine Side Effects Report #5323678-7
CAPECITABINE problem was reported by a Physician from UNITED KINGDOM on May 02, 2007. Male patient, 69 years of age, weighting 158.7 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: cerebral haemorrhage, dyspnoea. CAPECITABINE dosage: unknown. During the same period patient was treated with CISPLATIN, EPIRUBICIN. Patient was hospitalized. Patient died on 12/28/2006.

Capecitabine Side Effects Report #5325097-6
Physician from JAPAN reported CAPECITABINE problem on Apr 12, 2007. Female patient, 50 years of age, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: intestinal perforation. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, OXALIPLATIN. Patient recovered.

Capecitabine Side Effects Report #5326083-2
CAPECITABINE problem was reported by a Physician from AUSTRALIA on May 01, 2007. Male patient, 64 years of age, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: nephritis interstitial. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, MITOMYCIN. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5326175-8
Physician from UNITED STATES reported CAPECITABINE problem on May 08, 2007. Male patient, 61 years of age, weighting 250.0 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: dehydration, diabetic ketoacidosis, staphylococcal sepsis, vomiting. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, OXALIPLATIN, HYDROCHLOROTHIAZIDE, ASPIRIN, NITROGLYCERIN, TENORMIN, VASOTEC, TRICOR. Patient died on 10/15/2006.

Capecitabine Side Effects Report #5326585-9
CAPECITABINE problem was reported by a Health Professional from UNITED KINGDOM on May 09, 2007. Male patient, 42 years of age, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: anaphylactoid reaction, chest pain, muscle spasms. CAPECITABINE dosage: unknown. During the same period patient was treated with ELOXATIN. Patient recovered.

Capecitabine Side Effects Report #5327259-0
Health Professional from AUSTRALIA reported CAPECITABINE problem on May 08, 2007. Male patient, 57 years of age, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: diarrhoea, partial seizures. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5328592-9
CAPECITABINE problem was reported by a Physician from AUSTRIA on May 04, 2007. Female patient, 55 years of age, weighting 127.9 lb, was diagnosed with breast cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: leukopenia. CAPECITABINE dosage: unknown. During the same period patient was treated with TRASTUZUMAB, DOCETAXEL, EPIRUBICIN, PANTOPRAZOLE, BLOPRESS. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5328710-2
Physician from AUSTRALIA reported CAPECITABINE problem on May 11, 2007. Female patient, 32 years of age, weighting 181.9 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: diarrhoea, metabolic acidosis, oesophagitis, sepsis. CAPECITABINE dosage: 1000 MG/M2 TWICE-DAILY, DAYS 1-15 (WITH FIRST DOSE THE EVENING OF DAY 1 AND LAST DOSE IN THE EVENIN+. During the same period patient was treated with BEVACIZUMAB, OXALIPLATIN, PLENDIL, LIPITOR, EZETROL, DIAMICRON, ASTRIX. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5328711-4
CAPECITABINE problem was reported by a Physician from UNITED STATES on May 07, 2007. Male patient, 82 years of age, weighting 151.2 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, atrial flutter, dehydration, diarrhoea, flatulence, hypotension, ileus, ischaemic stroke, klebsiella sepsis. CAPECITABINE dosage: unknown. During the same period patient was treated with OXALIPLATIN, BEVACIZUMAB. Patient was hospitalized. Patient died on 04/20/2007.

Capecitabine Side Effects Report #5328712-6
Physician from UNITED KINGDOM reported CAPECITABINE problem on May 10, 2007. Female patient, 71 years of age, weighting 185.2 lb, was diagnosed with colon cancer, hyperthyroidism, hypertension and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: cardiac arrest. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, CARBIMAZOLE, BENDROFLUMETHIAZIDE, AMLODIPINE. Patient died on 04/06/2007.

Capecitabine Side Effects Report #5328729-1
CAPECITABINE problem was reported by a Physician from AUSTRIA on May 04, 2007. Female patient, 55 years of age, weighting 127.9 lb, was diagnosed with breast cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: leukopenia. CAPECITABINE dosage: unknown. During the same period patient was treated with TRASTUZUMAB, DOCETAXEL, EPIRUBICIN, PANTOPRAZOLE, BLOPRESS. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5328793-X
Physician from UNITED KINGDOM reported CAPECITABINE problem on May 08, 2007. Male patient, 74 years of age, weighting 173.1 lb, was diagnosed with colon cancer, thrombosis prophylaxis, asthma, hypertension and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: arteriospasm coronary. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, ASPIRIN, BECLOMETHASONE DIPROPIONATE, RAMIPRIL. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5328794-1
CAPECITABINE problem was reported by a Physician from UNITED STATES on May 08, 2007. Female patient, 62 years of age, weighting 140.0 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: hepatic cirrhosis. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, ABRAXANE, DOCETAXEL. Patient recovered.

Capecitabine Side Effects Report #5329876-0
Physician from UNITED STATES reported CAPECITABINE problem on Apr 18, 2007. Female patient, 60 years of age, weighting 166.9 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: diaphragmatic hernia. CAPECITABINE dosage: unknown. During the same period patient was treated with LEVOTHYROXINE, DICLOFENAC, CLONAZEPAM, BUPROPION HYDROCHLORIDE, ALBUTEROL, QUININE SULPHATE. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5330067-8
CAPECITABINE problem was reported by a Physician from FRANCE on May 10, 2007. Male patient, 52 years of age, was diagnosed with metastatic gastric cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: agranulocytosis, mucosal inflammation, pyrexia. CAPECITABINE dosage: unknown. During the same period patient was treated with EPIRUBICIN, CISPLATIN, DURAGESIC, PRIMPERAN, BICARBONATE. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5330074-5
Physician from FRANCE reported CAPECITABINE problem on May 11, 2007. Female patient, 59 years of age, was diagnosed with metastatic gastric cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: colitis ischaemic. CAPECITABINE dosage: unknown. During the same period patient was treated with IRINOTECAN, FOLINIC ACID, FLUOROURACIL. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5330076-9
CAPECITABINE problem was reported by a Physician from UNITED STATES on May 10, 2007. Female patient, 71 years of age, weighting 149.0 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: small intestinal perforation. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, OXALIPLATIN, FOSAMAX, IRON SULPHATETHIAMIN COMPOUND, PROPANOL, LEVOTHYROXINE, LISINOPRIL. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5330077-0
Physician from PANAMA reported CAPECITABINE problem on May 11, 2007. Male patient, 68 years of age, weighting 97.44 lb, was diagnosed with gastric cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: pneumonia, sepsis. CAPECITABINE dosage: DOSE AS PER CLINICAL PROTOCOL. ACTUAL DOSE: 1300 MG. GIVEN FOR 14 DAYS EVERY 3 WEEKS (FROM PM OF DA+. During the same period patient was treated with CISPLATIN. Patient was hospitalized. Patient died on 03/07/2007.

Capecitabine Side Effects Report #5330254-9
CAPECITABINE problem was reported by a Physician from UNITED KINGDOM on May 16, 2007. Male patient, weighting 151.0 lb, was diagnosed with gastric cancer, hypertension, hypercholesterolaemia, gastric disorder and was treated with CAPECITABINE. CAPECITABINE dosage: unknown. During the same period patient was treated with DOCETAXEL, OXALIPLATIN, PERINDOPRIL, SIMVASTATIN, LANSOPRAZOLE. Patient died on 05/02/2007.

Capecitabine Side Effects Report #5330959-X
Physician from JAPAN reported CAPECITABINE problem on May 15, 2007. Male patient, 71 years of age, weighting 143.3 lb, was diagnosed with gastric cancer, haemorrhoids and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: gout, pyrexia. CAPECITABINE dosage: unknown. During the same period patient was treated with TRASTUZUMAB, CISPLATIN, FERROUS CITRATE, ZOLPIDEM TARTRATE, DIFLUCORTOLONE VALERATE, DICYCLOMINE. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5330975-8
CAPECITABINE problem was reported by a Health Professional from UNITED KINGDOM on May 11, 2007. Female patient, 78 years of age, was diagnosed with deep vein thrombosis, pain and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: breast haemorrhage, international normalised ratio increased. CAPECITABINE dosage: unknown. During the same period patient was treated with WARFARIN, METFORMIN, PARACETAMOL. Patient recovered.

Capecitabine Side Effects Report #5330983-7
Health Professional from UNITED KINGDOM reported CAPECITABINE problem on May 11, 2007. Male patient, 42 years of age, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: anaphylactoid reaction, chest pain, muscle spasms. CAPECITABINE dosage: unknown. During the same period patient was treated with ELOXATIN. Patient recovered.

Capecitabine Side Effects Report #5331370-8
CAPECITABINE problem was reported by a Physician from GERMANY on May 11, 2007. Female patient, weighting 102.5 lb, was diagnosed with colorectal cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: dehydration, hypotension, nausea, vomiting. CAPECITABINE dosage: unknown. During the same period patient was treated with CETUXIMAB, ELOXATIN, BEVACIZUMAB. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5332137-7
Physician from UNITED STATES reported CAPECITABINE problem on May 14, 2007. Female patient, 58 years of age, was diagnosed with rectal cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: cellulitis. CAPECITABINE dosage: unknown. During the same period patient was treated with ELOXATIN, CETUXIMAB. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5332246-2
CAPECITABINE problem was reported by a Physician from UNITED STATES on July 22, 2005. Female patient, 54 years of age, was diagnosed with breast cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: malignant neoplasm progression, pleural effusion, pneumonitis. CAPECITABINE dosage: unknown. During the same period patient was treated with IXABEPILONE, GLUCOPHAGE. Patient was hospitalized. Patient died on 08/04/2005.

Capecitabine Side Effects Report #5333383-9
Physician from AUSTRALIA reported CAPECITABINE problem on May 15, 2007. Male patient, 68 years of age, weighting 165.3 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: proteinuria. CAPECITABINE dosage: 2500 MG/M2, DAYS 1-14, EVERY THREE WEEKS AS PER PROTOCOL. REPORTED AS 1200MG/M2 PER DAY.. During the same period patient was treated with BEVACIZUMAB, MITOMYCIN, ACETYLSALICYLIC ACID SRT. Patient recovered.

Capecitabine Side Effects Report #5333385-2
CAPECITABINE problem was reported by a Physician from UNITED KINGDOM on May 16, 2007. Male patient, 69 years of age, weighting 158.7 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: bronchopneumonia, cerebral haemorrhage. CAPECITABINE dosage: DOSE REPORTED AS 2150. 1250 MG/M2/DAY IN TWO DIVIDED DOSES OR 625 MG/M2 TWICE DAILY.. During the same period patient was treated with CISPLATIN, EPIRUBICIN. Patient was hospitalized. Patient died on 12/28/2006.

Capecitabine Side Effects Report #5334844-9
Physician from UNITED KINGDOM reported CAPECITABINE problem on May 16, 2007. Female patient, 62 years of age, weighting 158.7 lb, was diagnosed with colon cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: arteriospasm coronary. CAPECITABINE dosage: 2000 MG IN THE MORNING AND 2500 MG IN THE EVENING FOR 14 DAYS OF 21 DAY CYCLE (2500 MG/M2 DAILY DAY+. During the same period patient was treated with BEVACIZUMAB, GAVISCON. Patient recovered.

Capecitabine Side Effects Report #5334927-3
CAPECITABINE problem was reported by a Physician from SPAIN on May 14, 2007. Male patient, 74 years of age, weighting 194.0 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: mucosal inflammation. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, METOCLOPRAMIDE, OMEPRAZOLE, LOPERAMIDE, FLUCONAZOLE, NISTATIN. Patient was hospitalized. Patient died on 05/13/2007.

Capecitabine Side Effects Report #5335020-6
Physician from CANADA reported CAPECITABINE problem on May 17, 2007. Male patient was diagnosed with colorectal cancer metastatic and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: loss of consciousness. CAPECITABINE dosage: 800 MG TWICE A DAY FROM DAY 1 TO DAY 15, Q3W. During the same period patient was treated with OXALIPLATIN, DURAGESIC. Patient was hospitalized and became disabled. Patient recovered.

Capecitabine Side Effects Report #5335023-1
CAPECITABINE problem was reported by a Physician from UNITED STATES on May 21, 2007. Male patient was diagnosed with colorectal cancer metastatic and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: mucosal inflammation, multi-organ failure. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, OXALIPLATIN. Patient was hospitalized. Patient died on 04/20/2007.

Capecitabine Side Effects Report #5336879-9
Health Professional from UNITED STATES reported CAPECITABINE problem on May 24, 2007. Male patient, 66 years of age, was diagnosed with rectal cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: dehydration, diarrhoea. CAPECITABINE dosage: unknown. During the same period patient was treated with OCALIPLATIN, CETUXIMAB. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5336949-5
CAPECITABINE problem was reported by a Physician from AUSTRALIA on May 17, 2007. Male patient, 75 years of age, weighting 220.5 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: hypertension, transient ischaemic attack. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, MITOMYCIN, SOLPRIN, PERINDOPRIL ERBUMINE, SOTALOL, ZYLOPRIM. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5336956-2
Physician from UNITED KINGDOM reported CAPECITABINE problem on May 14, 2007. Female patient, 37 years of age, weighting 132.3 lb, was diagnosed with breast cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: arteriospasm coronary. CAPECITABINE dosage: unknown. During the same period patient was treated with EPIRUBICIN. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5337035-0
CAPECITABINE problem was reported by a Physician from UNITED STATES on May 17, 2007. Male patient, 54 years of age, weighting 282.0 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: arrhythmia supraventricular, hypertension, myocardial infarction, ventricular arrhythmia. CAPECITABINE dosage: unknown. During the same period patient was treated with DOCETAXEL. Patient was hospitalized. Patient died on 08/24/2005.

Capecitabine Side Effects Report #5338470-7
Physician from GERMANY reported CAPECITABINE problem on May 24, 2007. Female patient, 31 years of age, weighting 152.1 lb, was diagnosed with breast cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: erysipelas, impetigo. CAPECITABINE dosage: unknown. During the same period patient was treated with PACLITAXEL. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5338563-4
CAPECITABINE problem was reported by a Physician from UNITED KINGDOM on May 14, 2007. Female patient, 37 years of age, weighting 132.3 lb, was diagnosed with breast cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: arteriospasm coronary. CAPECITABINE dosage: unknown. During the same period patient was treated with EPIRUBICIN. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5340324-7
Physician from UNITED STATES reported CAPECITABINE problem on May 21, 2007. Male patient, 82 years of age, weighting 151.2 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: mucosal inflammation, multi-organ failure. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, OXALIPLATIN, ASPIRIN, VITAMIN NOS, GLUCOSAMINE, LECITHIN, SAW PALMETTO, METAMUCIL. Patient was hospitalized. Patient died on 04/20/2007.

Capecitabine Side Effects Report #5340381-8
CAPECITABINE problem was reported by a Physician from GERMANY on May 11, 2007. Female patient, weighting 102.5 lb, was diagnosed with colorectal cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: asthenia, dehydration, hypotension, nausea, vomiting. CAPECITABINE dosage: unknown. During the same period patient was treated with CETUXIMAB, ELOXATIN, BEVACIZUMAB. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5342204-X
Physician from FRANCE reported CAPECITABINE problem on May 25, 2007. Male patient, 56 years of age, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: respiratory failure, staphylococcal infection. CAPECITABINE dosage: unknown. During the same period patient was treated with OXALIPLATIN, DOCETAXEL. Patient died on 09/11/2006.

Capecitabine Side Effects Report #5342208-7
CAPECITABINE problem was reported by a Physician from FRANCE on May 25, 2007. Male patient, 56 years of age, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: disseminated intravascular coagulation, gastrointestinal haemorrhage. CAPECITABINE dosage: unknown. During the same period patient was treated with OXALIPLATIN, RAMOSETRON. Patient recovered.

Capecitabine Side Effects Report #5342230-0
Physician from JAPAN reported CAPECITABINE problem on May 24, 2007. Male patient, 57 years of age, weighting 140.4 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: diarrhoea, enteritis infectious. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, OXALIPLATIN. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5342231-2
CAPECITABINE problem was reported by a Physician from NETHERLANDS on May 21, 2007. Male patient, 59 years of age, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: anaemia, dehydration, diarrhoea, hypomagnesaemia, nausea. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, OXALIPLATIN, CETUXIMAB, METOCLOPRAMIDE. Patient was hospitalized. Patient died on 05/03/2007.

Capecitabine Side Effects Report #5344153-X
Physician from FRANCE reported CAPECITABINE problem on May 24, 2007. Male patient, 56 years of age, weighting 207.2 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: anastomotic complication. CAPECITABINE dosage: unknown. During the same period patient was treated with OXALIPLATIN. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5344161-9
CAPECITABINE problem was reported by a Physician from UNITED KINGDOM on May 30, 2007. Female patient, 51 years of age, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: amnesia, colitis ulcerative, cystitis klebsiella, dehydration, diarrhoea, herpes zoster, hypokalaemia, hyponatraemia, ileus. CAPECITABINE dosage: unknown. During the same period patient was treated with LAPATINIB, HYDROCORTISONE. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5344165-6
Physician from UNITED STATES reported CAPECITABINE problem on May 23, 2007. Female patient, 74 years of age, weighting 168.0 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: bundle branch block left. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, OXALIPLATIN, METOPROLOL SUCCINATE, PHENERGAN, GLYBURIDE, LISINOPRIL, WARFARIN. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5344171-1
CAPECITABINE problem was reported by a Physician from AUSTRALIA on May 28, 2007. Female patient, 65 years of age, weighting 152.1 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: tumour perforation. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB. Patient was hospitalized. Patient died on 11/06/2006.

Capecitabine Side Effects Report #5346040-X
Physician from UNITED STATES reported CAPECITABINE problem on May 29, 2007. Female patient, 38 years of age, was diagnosed with breast cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: febrile neutropenia. CAPECITABINE dosage: unknown. During the same period patient was treated with IXABEPILONE. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5347834-7
CAPECITABINE problem was reported by a Physician from GERMANY on May 25, 2007. Female patient, 56 years of age, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: blood pressure increased, haemoglobin decreased, lacrimation increased, palmar-plantar erythrodysaesthesia syndrome, paraesthesia, rash, sarcoidosis, skin ulcer. CAPECITABINE dosage: unknown. During the same period patient was treated with NEXAVAR, CLONIDINE, ZOLOFT. Patient recovered.

Capecitabine Side Effects Report #5349415-8
Physician from UNITED KINGDOM reported CAPECITABINE problem on June 01, 2007. Female patient, 71 years of age, weighting 185.2 lb, was diagnosed with colon cancer, hyperthyroidism, hypertension and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: myocardial infarction. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, CARBIMAZOLE, BENDROFLUMETHIAZIDE, AMLODIPINE. Patient died on 04/06/2007.

Capecitabine Side Effects Report #5349417-1
CAPECITABINE problem was reported by a Physician from FRANCE on May 29, 2007. Female patient, 59 years of age, was diagnosed with metastatic gastric cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: colitis ischaemic. CAPECITABINE dosage: unknown. During the same period patient was treated with IRINOTECAN, FOLINIC ACID, FLUOROURACIL. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5350759-4
Physician from AUSTRALIA reported CAPECITABINE problem on May 29, 2007. Female patient, 81 years of age, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: renal failure acute. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, MITOMYCIN, FLOXACILLIN. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5350775-2
CAPECITABINE problem was reported by a Physician from AUSTRALIA on May 29, 2007. Female patient, 19 years of age, weighting 110.2 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: colitis. CAPECITABINE dosage: AS PER PROTOCOL GIVEN 1000 MG/M2 TWICE DAILY FORM THE EVENING OF DAY ONE UNTIL THE MORNING OF DAY F+. During the same period patient was treated with BEVACIZUMAB, OXALIPLATIN. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5352549-5
Physician from AUSTRALIA reported CAPECITABINE problem on May 31, 2007. Male patient, 68 years of age, weighting 165.3 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: proteinuria. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, MITOMYCIN, ACETYLSALICYLIC ACID SRT. Patient recovered.

Capecitabine Side Effects Report #5352550-1
CAPECITABINE problem was reported by a Physician from AUSTRALIA on May 29, 2007. Male patient, 75 years of age, weighting 220.5 lb, was diagnosed with prophylaxis and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: hypertension, transient ischaemic attack. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, MITOMYCIN, SOLPRIN, PERINDOPRIL ERBUMINE, SOTALOL, ZYLOPRIM, ASPIRIN. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5353765-9
Physician from AUSTRALIA reported CAPECITABINE problem on May 31, 2007. Male patient, 83 years of age, weighting 174.2 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: leukoencephalopathy, splenic infarction. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB. Patient recovered.

Capecitabine Side Effects Report #5353768-4
CAPECITABINE problem was reported by a Physician from GERMANY on June 01, 2007. Male patient, 73 years of age, weighting 128.3 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: cholangitis, stomatitis. CAPECITABINE dosage: unknown. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5355892-9
Physician from AUSTRALIA reported CAPECITABINE problem on June 04, 2007. Female patient, 47 years of age, weighting 202.8 lb, was diagnosed with hypertension, pain and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: intestinal perforation, small intestinal obstruction. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, LIPITOR, OXYCONTIN, ENDONE, PARACETAMOL. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5356006-1
CAPECITABINE problem was reported by a Physician from GERMANY on Mar 26, 2007. Female patient was diagnosed with bile duct cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: cholangitis, fatigue, leukopenia, nausea, septic shock, thrombocytopenia, transaminases increased. CAPECITABINE dosage: 750 MG/M2. During the same period patient was treated with GEMCITABINE, OXALIPLATIN. Patient died.

Capecitabine Side Effects Report #5356844-5
Physician from GERMANY reported CAPECITABINE problem on June 05, 2007. Female patient, 67 years of age, was diagnosed with breast cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: abdominal haematoma. CAPECITABINE dosage: unknown. During the same period patient was treated with IBANDRONIC ACID. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5360689-X
CAPECITABINE problem was reported by a Physician from GERMANY on June 06, 2007. Female patient, 63 years of age, weighting 144.0 lb, was diagnosed with breast cancer metastatic, prophylaxis and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: mastitis. CAPECITABINE dosage: unknown. During the same period patient was treated with PACLITAXEL, EPIRUBICIN, CYCLOPHOSPHAMIDE, DARBEPOETIN ALFA, NEULASTA, CIPROFLOXACIN, PASPERTIN, FORTECORTIN. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5362255-9
Physician from UNITED KINGDOM reported CAPECITABINE problem on June 14, 2007. Male patient, weighting 195.1 lb, was diagnosed with colorectal cancer metastatic and was treated with CAPECITABINE. CAPECITABINE dosage: 1000 MG/M2 BID DAYS 1-14. During the same period patient was treated with CETUXIMAB, OXALIPLATIN. Patient died on 05/28/2007.

Capecitabine Side Effects Report #5365352-7
CAPECITABINE problem was reported by a Health Professional from UNITED KINGDOM on June 14, 2007. Female patient, 63 years of age, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: acute myeloid leukaemia, lymphadenopathy, palmar-plantar erythrodysaesthesia syndrome, rectal cancer, urinary tract infection. CAPECITABINE dosage: unknown. During the same period patient was treated with MISTLETOE, UKRAIN. Patient died on 09/01/2006.

Capecitabine Side Effects Report #5365358-8
Physician from JAPAN reported CAPECITABINE problem on May 12, 2007. Female patient, 71 years of age, weighting 103.2 lb, was diagnosed with gastric cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: cholecystitis acute. CAPECITABINE dosage: unknown. During the same period patient was treated with CISPLATIN, FERRIC OXIDE, FAMOTIDINE, FERROUS CITRATE, PANTETHINE, MAGNESIUM OXIDE, DOMPERIDONE, FLURBIPROFEN AXETIL. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5367191-X
CAPECITABINE problem was reported by a Physician from NETHERLANDS on June 14, 2007. Female patient, 65 years of age, weighting 114.6 lb, was diagnosed with gastric cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: gastric stenosis. CAPECITABINE dosage: 1650MG BID. 2 WEEKS OF TREATMENT AND 1 WEEK OF REST.. During the same period patient was treated with EPIRUBICIN, CISPLATIN. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5368349-6
Physician from GERMANY reported CAPECITABINE problem on Sept 25, 2006. Female patient, 48 years of age, weighting 158.7 lb, was diagnosed with breast cancer metastatic and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: hypersensitivity. CAPECITABINE dosage: unknown. During the same period patient was treated with TAXOL, EPIRUBICIN, ARANESP, CYCLOPHOSPHAMIDE, INNOHEP, BROMAZANIL. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5368882-7
CAPECITABINE problem was reported by a Health Professional from UNITED STATES on June 21, 2007. Female patient, weighting 149.0 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: neutropenia, white blood cell count decreased. CAPECITABINE dosage: 900MG BID FOR 14 DAYS PO. During the same period patient was treated with GEMCITABINE. Patient recovered.

Capecitabine Side Effects Report #5369191-2
Physician from FRANCE reported CAPECITABINE problem on June 12, 2007. Male patient, 66 years of age, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: lung disorder, small intestinal obstruction. CAPECITABINE dosage: unknown. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5369194-8
CAPECITABINE problem was reported by a Health Professional from UNITED STATES on June 14, 2007. Female patient, 40 years of age, was diagnosed with colorectal cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: jaundice cholestatic, nausea, neoplasm progression, vomiting. CAPECITABINE dosage: unknown. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5370316-3
Physician from NEW ZEALAND reported CAPECITABINE problem on June 15, 2007. Male patient, 66 years of age, weighting 142.6 lb, was diagnosed with colorectal cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: gastrointestinal pain, large intestine perforation, sepsis, small intestinal obstruction, vomiting. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, OXALIPLATIN, ASPIRIN, ACCUPRIL, NYSTATIN, DIFFLAM, AQUEOUS CREAM. Patient was hospitalized. Patient died on 06/16/2007.

Capecitabine Side Effects Report #5370336-9
CAPECITABINE problem was reported by a Physician from ITALY on June 14, 2007. Female patient, 50 years of age, weighting 169.8 lb, was diagnosed with colorectal cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: intestinal obstruction. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, OXALIPLATIN, LANSOX, DELTACORTENE, PLASIL, NEORECORMON, OSIPINE. Patient was hospitalized. Patient died on 05/01/2007.

Capecitabine Side Effects Report #5370361-8
Physician from JAPAN reported CAPECITABINE problem on June 18, 2007. Female patient, 70 years of age, weighting 103.2 lb, was diagnosed with gastric cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: cholecystitis. CAPECITABINE dosage: unknown. During the same period patient was treated with CISPLATIN, FERRIC OXIDE, FAMOTIDINE, FERROUS CITRATE, PANTETHINE, MAGNESIUM OXIDE, DOMPERIDONE, FLURBIPROFEN AXETIL. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5372082-4
CAPECITABINE problem was reported by a Physician from UNITED STATES on June 08, 2007. Female patient, 47 years of age, weighting 110.9 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: cholestasis, coma hepatic, hepatic failure, hepatic fibrosis, metastases to liver, tumour necrosis. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, ABRAXANE. Patient was hospitalized. Patient died on 04/18/2007.

Capecitabine Side Effects Report #5372084-8
Physician from NEW ZEALAND reported CAPECITABINE problem on June 15, 2007. Female patient, 75 years of age, weighting 172.4 lb, was diagnosed with colorectal cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: diarrhoea, septic shock. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, OXALIPLATIN, ASPIRIN, CALCIUM SANDOZ, DURIDE, LEVOTHYROXINE, LIPEX, LOPERAMIDE. Patient was hospitalized. Patient died on 06/15/2007.

Capecitabine Side Effects Report #5372302-6
CAPECITABINE problem was reported by a Physician from SPAIN on June 11, 2007. Male patient, 82 years of age, weighting 127.9 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: pneumonia. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, NOLOTIL, PRIMPERAN, FORTECORTIN, ALDACTONE, OMEPRAZOLE, ORFIDAL, ADOLONTA. Patient was hospitalized. Patient died on 06/08/2007.

Capecitabine Side Effects Report #5372340-3
Physician from GERMANY reported CAPECITABINE problem on June 14, 2007. Female patient, 75 years of age, weighting 156.5 lb, was diagnosed with gastric cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: cardiovascular disorder. CAPECITABINE dosage: unknown. During the same period patient was treated with TRASTUZUMAB, CISPLATIN. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5373641-5
CAPECITABINE problem was reported by a Physician from BRAZIL on June 19, 2007. Female patient, 69 years of age, weighting 202.8 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: diarrhoea, mucosal inflammation, renal failure. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, DOCETAXEL. Patient was hospitalized. Patient died on 03/17/2007.

Capecitabine Side Effects Report #5373830-X
Health Professional from ITALY reported CAPECITABINE problem on June 26, 2007. Female patient was diagnosed with colorectal cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: intestinal obstruction. CAPECITABINE dosage: 3500 MG 14 X PER MONTH. During the same period patient was treated with BEVACIZUMAB, OSIPINE, NEORECORMON, PLASIL, DELTACORTENE, LANSOX, OXALIPLATIN. Patient was hospitalized. Patient died on 05/01/2007.

Capecitabine Side Effects Report #5374162-6
CAPECITABINE problem was reported by a Consumer or non-health professional from UNITED STATES on Dec 06, 2006. Male patient, 52 years of age, was diagnosed with rectal cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: palmar-plantar erythrodysaesthesia syndrome. CAPECITABINE dosage: 1500 MG 2 PER DAY. Patient recovered.

Capecitabine Side Effects Report #5374217-6
Physician from UNITED STATES reported CAPECITABINE problem on Aug 02, 2006. Female patient, 59 years of age, was diagnosed with cervix cancer metastatic and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: febrile neutropenia, mucosal inflammation, palmar-plantar erythrodysaesthesia syndrome, pancytopenia, renal failure, urinary tract infection. CAPECITABINE dosage: 1100 MG/M2 2 PER DAY. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5374274-7
CAPECITABINE problem was reported by a Physician from ISRAEL on Mar 26, 2007. Female patient, 59 years of age, weighting 174.2 lb, was diagnosed with colorectal cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: abdominal pain, haemorrhoids, intestinal obstruction, oesophagitis, urinary tract infection, vomiting. CAPECITABINE dosage: unknown. During the same period patient was treated with BEVACIZUMAB, CAMPTOSAR, PROCTO, CONVERTIN, GASTRO, OXYCONTIN, DURAGESIC, ZANTAC. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5374781-7
Physician from GERMANY reported CAPECITABINE problem on June 19, 2007. Female patient, 63 years of age, weighting 144.0 lb, was diagnosed with breast cancer metastatic, prophylaxis and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: mastitis. CAPECITABINE dosage: unknown. During the same period patient was treated with PACLITAXEL, EPIRUBICIN, CYCLOPHOSPHAMIDE, DARBEPOETIN ALFA, NEULASTA, CIPROFLOXACIN, PASPERTIN, FORTECORTIN. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5374788-X
CAPECITABINE problem was reported by a Physician from UNITED STATES on June 21, 2007. Male patient, 62 years of age, was diagnosed with colorectal cancer metastatic and was treated with CAPECITABINE. CAPECITABINE dosage: unknown. During the same period patient was treated with CETUXIMAB, OXALIPLATIN, FLUOROURACIL. Patient died on 05/28/2007.

Capecitabine Side Effects Report #5375976-9
Health Professional from UNITED STATES reported CAPECITABINE problem on June 27, 2007. Female patient, weighting 149.0 lb, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: neutrophil count abnormal, white blood cell disorder. CAPECITABINE dosage: 900MG BID FOR 14 DAYS PO. During the same period patient was treated with GEMCITABINE. Patient recovered.

Capecitabine Side Effects Report #5041086-3
CAPECITABINE problem was reported by a Physician from NETHERLANDS on June 01, 2006. Female patient, 73 years of age, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: dehydration, diarrhoea, duodenal ulcer haemorrhage, haematemesis, mucosal inflammation, stomatitis. CAPECITABINE dosage: ON DAYS 1-14 DOSING AND FREQUENCY AS PER PROTOCOL REPORTED DOSE = 2 X 2000MG. During the same period patient was treated with AVASTIN, OXALIPLATIN, ERBITUX, NSAID, ASCAL. Patient was hospitalized. Patient died on 04/26/2006.

Capecitabine Side Effects Report #5041110-8
Physician from NETHERLANDS reported CAPECITABINE problem on June 02, 2006. Female patient, 70 years of age, was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: pancreatitis. CAPECITABINE dosage: DAYS 1-14 OF A 3 WEEK CYCLE DOSE AND FREQUENCY AS PER PROTCOL REPORTED = 2000MG. During the same period patient was treated with AVASTIN, OXALIPLATIN, METOCLOPRAMIDE, LOPERAMIDE. Patient was hospitalized. Patient recovered.

Capecitabine Side Effects Report #5041288-6
CAPECITABINE problem was reported by a Physician from BELGIUM on Apr 28, 2006. Female patient, 68 years of age, weighting 145.5 lb, was diagnosed with breast cancer and was treated with CAPECITABINE. After drug was administered, patient experienced the following problems/side effects: anorexia, diarrhoea, febrile neutropenia, herpes zoster, stomatitis, vomiting. CAPECITABINE dosage: unknown. During the same period patient was treated with TAXOTERE, TRAZOLAN, BETASERC, SERENASE, POTASSIUM. Patient was hospitalized. Patient recovered.

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Drug Information: Capecitabine

URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a699003.html

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IMPORTANT WARNING:

When used in combination with anticoagulants ('blood thinners') such as warfarin (Coumadin), capecitabine can cause serious bleeding and death. Tell your doctor if you are taking warfarin or phenprocoumon. Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to capecitabine. If you experience any unusual bleeding or bruising, call your doctor immediately.

About your treatment

Your doctor has ordered the drug capecitabine to help treat your illness. The drug is taken by mouth with tablets. Take capecitabine with water within 30 minutes after eating a meal.

This medication is used to treat:

metastatic colorectal cancer
metastatic breast cancer

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for information.

Capecitabine is in a class of drugs known as antimetabolites. Capecitabine resembles a normal cell nutrient needed by cancer cells to grow. The cancer cells take up the capecitabine, which then interferes with their growth. The length of treatment depends on the types of drugs you are taking, how well your body responds to them, and the type of cancer you have.

Precautions

Before taking capecitabine,

tell your doctor and pharmacist if you are allergic to a capecitabine, fluorouracil, or any other drugs.
tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially those listed in the IMPORTANT WARNING section, antacids, folic acid, leucovorin, phenytoin (Dilantin), and vitamins.
tell your doctor if you have or have ever had heart, liver, or kidney disease.
women who are pregnant or breast-feeding should tell their doctors before they begin taking this drug. You should not plan to have children while receiving chemotherapy or for a while after treatments. (Talk to your doctor for further details.) Use a reliable method of birth control to prevent pregnancy.
tell your doctor if you are breast-feeding. Capecitabine can cause serious side effects in nursing infants.
do not have any vaccinations (e.g., measles or flu shots) without talking to your doctor.

Side effects

Side effects from capecitabine are common and include:

diarrhea
nausea
vomiting
stomach pain
constipation
weakness
tiredness
dizziness
headache
sleeplessness
dry or itching skin
dehydration

If you experience any of the following symptoms or the one listed in the IMPORTANT WARNING section, call your doctor immediately:

severe diarrhea (more than four bowel movements each day or diarrhea at night)
decreased appetite (complete loss of appetite or only able to eat occasionally)
severe vomiting (more than one time in a 24-hour period)
tingling, numbness, pain, redness, or swelling of the hands or feet
sores or pain in the mouth or throat
fever or infection (a temperature of 100.5 degrees F or greater)
chills
sore throat
chest pain
rash

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].

Storage conditions

Keep capecitabine in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Brand name(s):

Xeloda®

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