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Carbon Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Carbon Monoxide Poisoning (8354803-1)
on May 02, 2012 Male from BELGIUM , 87 years of age, was treated with Carbon Monoxide. Directly after, patient experienced the unwanted or unexpected Carbon side effects: carbon monoxide poisoning. Carbon Monoxide dosage: N/A.
Associated medications used:
  • Duragesic-100 (2x100 Ug/hr + 4x50 Ug/hr Patches)
  • Zolpidem


Completed Suicide (8316639-7)
Patient was taking Carbon Black. Patient felt the following Carbon side effects: completed suicide on Apr 23, 2012 from UNITED STATES Additional patient health information: Female , 51 years of age, . Carbon Black dosage: Unk Ukn, Unk.
Multiple prescriptions taken:
  • Clozapine (Unk Ukn, Unk)


Completed Suicide (8065392-3)
Adverse event was reported on Jan 11, 2012 by a Male taking Carbon Monoxide (Dosage: N/A) . Location: UNITED STATES , 82 years of age, After Carbon was administered, patient encountered several Carbon side effects: completed suicide.
Multiple concurrent drugs taken:
  • Carbamazepine
  • Laxatives
  • Diazepam


Cardiac Arrest, Completed Suicide, Respiratory Arrest, Poisoning (8054775-3)
on Dec 27, 2011 Male from UNITED STATES , 82 years of age, was treated with Carbon Monoxide. Directly after, patient experienced the unwanted or unexpected Carbon side effects: cardiac arrest, completed suicide, respiratory arrest, poisoning. Carbon Monoxide dosage: (df Resipiratory (inhalation)).
Associated medications used:
  • Diazepam ((df))
  • Laxative (stimulant) ((df))
  • Carbamazepine ((df))



Completed Suicide, Cardio-respiratory Arrest (7755318-1)
on Sep 12, 2011 Patient from UNITED STATES , 49 years of age, was treated with Carbon Monoxide. Patient felt the following Carbon side effects: completed suicide, cardio-respiratory arrest. Carbon Monoxide dosage: Unk, Unk.
Multiple prescriptions taken:
  • Acetaminphen And Codeine Phosphate (Unk, Unk)
  • Bupropion Hcl (Unk, Unk)


Cardio-respiratory Arrest (7749658-X)
Patient was taking Carbon Monoxide/smoke. After Carbon was administered, patient encountered several Carbon side effects: cardio-respiratory arrest on Sep 12, 2011 from UNITED STATES Additional patient health information: Patient , child 4 years of age, . Carbon Monoxide/smoke dosage: Unk.
Multiple concurrent drugs taken:
  • Midazolam Hydrochloride (Unk, Unk)


Cardio-respiratory Arrest, Completed Suicide (7749640-2)
Adverse event was reported on Sep 12, 2011 by a Patient taking Carbon Monoxide (Dosage: Unk, Unk) . Location: UNITED STATES , 51 years of age, Directly after, patient experienced the unwanted or unexpected Carbon side effects: cardio-respiratory arrest, completed suicide.
Associated medications used:
  • Fluoxetine (Unk, Unk)
  • Olanzapine (Unk, Unk)


Migraine, Abasia, Pain In Extremity, Post Thrombotic Syndrome, Deep Vein Thrombosis, Oedema Peripheral (7493206-9)
on Dec 27, 2010 Female from UNITED STATES , 15 years of age, weighting 130.3 lb, was treated with Carbonyl Iron [iron Pentacarbonyl]. Patient felt the following Carbon side effects: migraine, abasia, pain in extremity, post thrombotic syndrome, deep vein thrombosis, oedema peripheral. Carbonyl Iron [iron Pentacarbonyl] dosage: N/A.
Multiple prescriptions taken:
  • Magnesium Sulfate
  • Hyoscyamine
  • Ibuprofen
  • Codeine Sulfate
  • Miralax
  • Librax (Unk Unk, Tid)
  • Hydromorphone Hcl (24 Mg (daily Dose), Q4hr, Intravenous)
  • Pantoprazole
Patient was hospitalized and became disabled.

Carbon Monoxide Poisoning, Cardiac Arrest, Thermal Burn, Respiratory Arrest (7413053-3)
on Mar 17, 2011 Female from UNITED STATES , 54 years of age, was treated with Carbon Monoxide (no Pref. Name). After Carbon was administered, patient encountered several Carbon side effects: carbon monoxide poisoning, cardiac arrest, thermal burn, respiratory arrest. Carbon Monoxide (no Pref. Name) dosage: Po.
Multiple concurrent drugs taken:
  • Oxycontin (Po)


Completed Suicide (7322430-0)
Patient was taking Carbon Black. Directly after, patient experienced the unwanted or unexpected Carbon side effects: completed suicide on Feb 22, 2011 from UNITED STATES Additional patient health information: Male , 81 years of age, . Carbon Black dosage: Unk, Unk.
Associated medications used:
  • Acetaminophen (Unk)


Cardio-respiratory Arrest (7309066-2)
Adverse event was reported on Feb 09, 2011 by a Male taking Carbon Monoxide (Dosage: N/A) . Location: UNITED STATES , 27 years of age, Patient felt the following Carbon side effects: cardio-respiratory arrest.
Multiple prescriptions taken:
  • Fentanyl-100


Cardio-respiratory Arrest, Thermal Burn, Carbon Monoxide Poisoning (7278959-7)
on Jan 25, 2011 Female from UNITED STATES , 54 years of age, was treated with Carbon Monoxide. After Carbon was administered, patient encountered several Carbon side effects: cardio-respiratory arrest, thermal burn, carbon monoxide poisoning. Carbon Monoxide dosage: Unk.
Multiple concurrent drugs taken:
  • Oxycodone Hcl (Unk)


Completed Suicide, Overdose (7227856-1)
on Jan 07, 2011 Female from UNITED STATES , 45 years of age, was treated with Carbon Tetrachloride. Directly after, patient experienced the unwanted or unexpected Carbon side effects: completed suicide, overdose. Carbon Tetrachloride dosage: N/A.
Associated medications used:
  • Tiamate


Toxicity To Various Agents (7227528-3)
Patient was taking Carbon. Patient felt the following Carbon side effects: toxicity to various agents on Jan 06, 2011 from UNITED STATES Additional patient health information: Male , 58 years of age, . Carbon dosage: N/A.
Multiple prescriptions taken:
  • Acetaminophen/diphenhydramine
  • Ethanol


Epistaxis, Vomiting (4879496-7)
Adverse event was reported on Sep 30, 2005 by a Female taking Carbon Monoxide (Dosage: N/A) . Location: UNITED STATES , 52 years of age, weighting 168.9 lb, After Carbon was administered, patient encountered several Carbon side effects: epistaxis, vomiting.
Multiple concurrent drugs taken:
  • Codeine (codeine)
  • Hydrocodone Bitartrate
  • Fluconazole
  • Diazepam
  • Alprazolam
  • Cyclobenzaprine (cyclobenzaprine)
  • Olanzapine
  • Verapamil


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It is very important to keep track of all side effects and discuss them with your doctor. If you think you may have a medical emergency, call your doctor or 911 immediately.

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Carbon Information

CALCIUM C LITHIUM C OXYGEN CA OXYGEN-CA OYSTER SH POTASSIUM SODIUM BI

Active Ingredient: AIR; CARB BARIUM CA CALCIUM C CARBON DI LITHIUM C OXYGEN OYSTER SH POTASSIUM SODIUM BI

More About Carbon

Side Effects reported to FDA: 15. View Carbon Adverse Reports

Carbon safety alerts: 2010 2007 2004 2001 2000

Reported deaths: 8

Reported hospitalizations: 1

Sodium Bicarbonate Injection, USP, 7.5% and 8.4%, 50 mL Single Dose Vials - Recall Due to Particulates in Some Vials

[Posted 12/29/2010]

 

AUDIENCE: Hospital Risk Managers, Pharmacy, Emergency Medicine

ISSUE: American Regent and FDA notified healthcare professionals of the nationwide recall of  specific lots of Sodium Bicarbonate Injection, USP, 7.5% and 8.4%, 50 mL Single Dose Vials because some vials of these lots contain particulates. Potential adverse events after intravenous administration include damage to blood vessels in the lung, localized swelling, and granuloma formation.

BACKGROUND: Sodium Bicarbonate Injection, USP, is indicated in the treatment of metabolic acidosis which may occur in severe renal disease, uncontrolled diabetes, circulatory insufficiency due to shock or severe dehydration, extracorporeal circulation of blood, cardiac arrest and severe primary lactic acidosis. Sodium bicarbonate is further indicated in the treatment of certain drug intoxications, including barbiturates (where dissociation of the barbiturate-protein complex is desired), in poisoning by salicylates or methyl alcohol and in hemolytic reactions requiring alkalinization of the urine to diminish nephrotoxicity of blood pigments. Sodium bicarbonate is also indicated in severe diarrhea which is often accompanied by a significant loss of bicarbonate.

RECOMMENDATION: Hospitals, infusion centers, clinics and other healthcare facilities should not use American Regent Inc., Sodium Bicarbonate Injection, USP, 7.5% and 8.4%, 50 mL Single Dose Vials with the lot #s list in the firm press release for patient care and should immediately quarantine any product for return.

Healthcare professionals and patients are encouraged to report adverse events or side effects related to the use of these products to the FDA's MedWatch Safety Information and Adverse Event Reporting Program:

  • Complete and submit the report Online: www.fda.gov/MedWatch/report.htm
  • Download form or call 1-800-332-1088 to request a reporting form, then complete and return to the address on the pre-addressed form, or submit by fax to 1-800-FDA-0178

 

[12/28/2010 - Firm Press Release - American Regent]

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