Cladribine Side Effects summary

Total Cladribine reports: 39. View

Cladribine FDA safety alerts: No.

Reported deaths: 13

Reported hospitalizations: 15.

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Recently reported Cladribine Side Effects


Common Cladribine Side Effects
Pancytopenia 21%
Myelodysplastic syndrome 15%
Pyrexia 15%
Rash  What is  Rash                                                                                                                                                                                                    8%
Renal impairment 8%
Cardiomyopathy  What is  Cardiomyopathy                                                                                                                                                                                          5%
Disseminated cytomegaloviral infection 5%
Disseminated intravascular coagulation 5%
Ejection fraction decreased 5%
Eosinophilia 5%
Hepatic enzyme increased 5%
Herpes zoster 5%
Hypersensitivity 5%
Hypoalbuminaemia 5%
Hypotension 5%
Lymphoma  What is  Lymphoma                                                                                                                                                                                                5%
Metastases to liver 5%
Neutrophil count decreased 5%
Oesophageal carcinoma 5%
Respiratory failure 5%
Sepsis  What is  Sepsis                                                                                                                                                                                                  5%
Swelling face 5%
Ventricular hypokinesia 5%
Aspergillosis 3%
Atrioventricular block complete 3%
Blood bilirubin increased 3%
Blood glucose increased 3%
Cerebral haemorrhage 3%
Chromosomal deletion 3%
Coombs test positive 3%
Cystitis haemorrhagic 3%
Cytokine storm 3%
Deafness 3%
Decreased activity 3%
Decreased appetite 3%
Dialysis  What is  Dialysis                                                                                                                                                                                                3%
Diffuse large b-cell lymphoma 3%
Diplopia 3%
Disorientation 3%
Diverticular perforation 3%
Dyspnoea 3%
Erythema 3%
Extravasation 3%
Eye irritation 3%
Fall  What is  Fall                                                                                                                                                                                                    3%
Febrile neutropenia 3%
Femur fracture 3%
Follicle centre lymphoma, follicular grade i, ii, iii refractory 3%
Fungal infection  What is  Fungal infection                                                                                                                                                                                        3%
Gastrointestinal haemorrhage 3%
Gingival bleeding 3%
Haemoglobin decreased 3%
Hairy cell leukaemia 3%
Headache  What is  Headache                                                                                                                                                                                                3%
Heart rate decreased 3%
Hepatitis acute 3%
Herpes simplex  What is  Herpes simplex                                                                                                                                                                                          3%
Hydronephrosis 3%
Hyperbilirubinaemia 3%
Hypoxia 3%
Injection site reaction 3%
Interstitial lung disease 3%
Listeriosis 3%
Lobar pneumonia 3%
Lung infiltration 3%
Malaise 3%
Malignant neoplasm progression 3%
Metastases to bone 3%
Mouth ulceration 3%
Mucosal ulceration 3%
Nephritis allergic 3%
Nephritis interstitial 3%
Neuroendocrine carcinoma of the skin 3%
Neutropenia 3%
Neutropenic sepsis 3%
Operative haemorrhage 3%
Pemphigus  What is  Pemphigus                                                                                                                                                                                               3%
Performance status decreased 3%
Pneumonia  What is  Pneumonia                                                                                                                                                                                               3%
Pseudomonas infection 3%
Pyelonephritis 3%
Refractory anaemia 3%
Renal failure 3%
Renal failure acute 3%
Reticulocyte count increased 3%
Skin reaction 3%
Staphylococcal impetigo 3%
Thrombocytopenia 3%
Thrombophlebitis superficial 3%
Tuberculosis  What is  Tuberculosis                                                                                                                                                                                            3%
Tumour lysis syndrome 3%
Urine output decreased 3%
Ventricular extrasystoles 3%
Waldenstrom's macroglobulinaemia refractory 3%

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Cladribine Side Effects Poll Results

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Cladribine Side Effects reported on Patientsville.com

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Cladribine Side Effects reported to FDA

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Cladribine Side Effects Report #5262612-5
Consumer or non-health professional from TUNISIA reported Cladribine side effect on Feb 19, 2007. Female patient, 56 years of age, was diagnosed with multiple sclerosis What is  multiple sclerosis and was treated with Cladribine. After drug was administered, patient experienced the following side effects: hepatitis acute. Cladribine dosage: (0.875 MG/KG, 7 IN 1 CYCLE, ORAL. Patient was hospitalized. Patient recovered.



Cladribine Side Effects Report #5268594-4
Cladribine side effect was reported by a Health Professional from UNITED STATES on Mar 15, 2007. Male patient, 77 years of age, weighting 217.0 lb, was diagnosed with hairy cell leukaemia and was treated with Cladribine. After drug was administered, patient experienced the following side effects: extravasation, injection site reaction. Cladribine dosage: 8.8 MG/DAY IV IN 500 ML NS CONTINUOUS INFUSION X 7 DAYS. Patient recovered.



Cladribine Side Effects Report #5315720-4
Consumer or non-health professional from UNITED STATES reported Cladribine side effect on Apr 30, 2007. Female patient, 39 years of age, was diagnosed with hairy cell leukaemia and was treated with Cladribine. After drug was administered, patient experienced the following side effects: pancytopenia. Cladribine dosage: 0.09MG/KG IV. Patient was hospitalized. Patient recovered.



Cladribine Side Effects Report #5082728-6
Cladribine side effect was reported by a Pharmacist from UNITED STATES on Aug 16, 2006. Male patient, 64 years of age, weighting 203.0 lb, was diagnosed with hairy cell leukaemia, febrile neutropenia and was treated with Cladribine. After drug was administered, patient experienced the following side effects: cytokine storm, dyspnoea, febrile neutropenia, hypotension, thrombophlebitis superficial. Cladribine dosage: unknown. During the same period patient was treated with ZOSYN, ADVICOR, PROZAC. Patient was hospitalized. Patient recovered.




Cladribine Side Effects Report #5110956-X
Health Professional from UNITED STATES reported Cladribine side effect on Sept 20, 2006. Female patient was diagnosed with malignant melanoma and was treated with Cladribine. After drug was administered, patient experienced the following side effects: blood bilirubin increased, blood glucose increased, coombs test positive, haemoglobin decreased, reticulocyte count increased. Cladribine dosage: 0.12 MG/KG QD SQ #5. During the same period patient was treated with LISINOPRIL, NORCO. Patient was hospitalized. Patient recovered.



Cladribine Side Effects Report #5115453-3
Cladribine side effect was reported by a Consumer or non-health professional from GERMANY on Sept 07, 2006. Female patient, 19 years of age, was diagnosed with relapsing-remitting multiple sclerosis and was treated with Cladribine. After drug was administered, patient experienced the following side effects: diplopia, erythema, eye irritation, headache What is  headache, hypersensitivity, mouth ulceration, mucosal ulceration, skin reaction, swelling face. Cladribine dosage: 1 FORMS (0.875 MG/KG, 5 IN 1 CYCLE) ORAL. During the same period patient was treated with IMPLANON. Patient recovered.



Cladribine Side Effects Report #5192269-3
Physician from UNITED STATES reported Cladribine side effect on Dec 22, 2006. Male patient, weighting 262.0 lb, was diagnosed with multiple sclerosis What is  multiple sclerosis and was treated with Cladribine. After drug was administered, patient experienced the following side effects: hepatic enzyme increased, metastases to bone, metastases to liver, oesophageal carcinoma. Cladribine dosage: unknown. During the same period patient was treated with NOVANTRONE, COPAXONE, ATORVASTATIN, METFORMIN, LISINOPRIL, ASPIRIN, AMITRIPTYLINE. Patient was hospitalized. Patient died on 09/24/2006.



Cladribine Side Effects Report #5449048-9
Cladribine side effect was reported by a Physician from JAPAN on Sept 03, 2007. Male patient was diagnosed with mantle cell lymphoma, prophylaxis and was treated with Cladribine. After drug was administered, patient experienced the following side effects: disseminated cytomegaloviral infection, hypoalbuminaemia, pancytopenia, renal impairment, respiratory failure, urine output decreased. Cladribine dosage: unknown. During the same period patient was treated with NOVANTRONE, BAKTAR, RITUXAN. Patient died on 04/07/2007.



Cladribine Side Effects Report #5566321-4
Physician from JAPAN reported Cladribine side effect on Dec 06, 2007. Female patient, 78 years of age, was diagnosed with hairy cell leukaemia, antifungal prophylaxis and was treated with Cladribine. After drug was administered, patient experienced the following side effects: eosinophilia, neutrophil count decreased, pyrexia. Cladribine dosage: unknown. During the same period patient was treated with ITRACONAZOLE, TRIMETHOPRIM. Patient was hospitalized. Patient recovered.




Cladribine Side Effects Report #5568099-7
Cladribine side effect was reported by a Physician from JAPAN on Dec 13, 2007. Female patient, 78 years of age, was diagnosed with hairy cell leukaemia, antifungal prophylaxis and was treated with Cladribine. After drug was administered, patient experienced the following side effects: eosinophilia, neutrophil count decreased, pyrexia. Cladribine dosage: unknown. During the same period patient was treated with ITRACONAZOLE, TRIMETHOPRIM. Patient was hospitalized. Patient recovered.



Cladribine Side Effects Report #5674320-7
Pharmacist from UNITED STATES reported Cladribine side effect on Dec 20, 2007. Male patient, 41 years of age, weighting 209.4 lb, was diagnosed with hairy cell leukaemia and was treated with Cladribine. After drug was administered, patient experienced the following side effects: neutropenia. Cladribine dosage: 0.09 MG/KG DAILY FOR A 7-DAY PRE. During the same period patient was treated with ALLOPURINOL, XANAX, DECADRON, COLACE, HEPARIN LOCK, DILAUDID, LEVAQUIN, ATIVAN. Patient recovered.



Cladribine Side Effects Report #5696515-9
Cladribine side effect was reported by a Physician from BRAZIL on Mar 28, 2008. Male patient, 34 years of age, was diagnosed with hairy cell leukaemia and was treated with Cladribine. After drug was administered, patient experienced the following side effects: gingival bleeding, pyrexia. Cladribine dosage: unknown. Patient was hospitalized. Patient recovered.



Cladribine Side Effects Report #5824019-9
Physician from FRANCE reported Cladribine side effect on July 22, 2008. Female patient, 73 years of age, was diagnosed with immunoblastic lymphoma and was treated with Cladribine. After drug was administered, patient experienced the following side effects: lymphoma What is  lymphoma. Cladribine dosage: unknown. Patient died.



Cladribine Side Effects Report #5841208-8
Cladribine side effect was reported by a Health Professional from UNITED KINGDOM on Aug 07, 2008. Male patient, 67 years of age, weighting 143.3 lb, was diagnosed with hairy cell leukaemia, hypertension, infection prophylaxis, hyperlipidaemia and was treated with Cladribine. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, hyperbilirubinaemia, hypersensitivity, hypotension, pyrexia, rash What is  rash, renal impairment, swelling face, thrombocytopenia. Cladribine dosage: unknown. During the same period patient was treated with ITRACONAZOLE, ACYCLOVIR, ALLOPURINOL, BENDROFLUMETHIAZIDE, CIPROFLOXACIN, SIMVASTATIN. Patient was hospitalized. Patient recovered.




Cladribine Side Effects Report #5853657-2
Physician from GREECE reported Cladribine side effect on Aug 12, 2008. Female patient, 30 years of age, weighting 149.9 lb, was diagnosed with multiple sclerosis What is  multiple sclerosis and was treated with Cladribine. After drug was administered, patient experienced the following side effects: cardiomyopathy What is  cardiomyopathy, ejection fraction decreased, ventricular hypokinesia. Cladribine dosage: unknown. Patient was hospitalized. Patient recovered.



Cladribine Side Effects Report #5948601-3
Cladribine side effect was reported by a Physician from JAPAN on Nov 05, 2008. Male patient, weighting 97.00 lb, was diagnosed with mantle cell lymphoma, infection susceptibility increased, prophylaxis and was treated with Cladribine. After drug was administered, patient experienced the following side effects: decreased activity, decreased appetite, disorientation, disseminated cytomegaloviral infection, hypoalbuminaemia, pancytopenia, pyrexia, renal impairment, respiratory failure. Cladribine dosage: unknown. During the same period patient was treated with NOVANTRONE, COTRIM, RITUXAN. Patient died on 04/07/2007.



Cladribine Side Effects Report #6022270-9
Physician from GREECE reported Cladribine side effect on Dec 29, 2008. Female patient, 30 years of age, weighting 149.9 lb, was diagnosed with multiple sclerosis What is  multiple sclerosis and was treated with Cladribine. After drug was administered, patient experienced the following side effects: cardiomyopathy What is  cardiomyopathy, ejection fraction decreased, ventricular hypokinesia. Cladribine dosage: unknown. Patient was hospitalized. Patient recovered.



Cladribine Side Effects Report #6092733-9
Cladribine side effect was reported by a Physician from FRANCE on July 22, 2008. Female patient, 73 years of age, was diagnosed with immunoblastic lymphoma and was treated with Cladribine. After drug was administered, patient experienced the following side effects: lymphoma What is  lymphoma. Cladribine dosage: unknown. Patient died.



Cladribine Side Effects Report #4616344-4
Physician from reported Cladribine side effect on Mar 09, 2005. Male patient, 73 years of age, weighting 140.0 lb, was diagnosed with hairy cell leukaemia and was treated with Cladribine. After drug was administered, patient experienced the following side effects: deafness. Cladribine dosage: unknown. Patient recovered.




Cladribine Side Effects Report #4625414-6
Cladribine side effect was reported by a Pharmacist from on July 02, 2004. Male patient, child 6 years of age, was diagnosed with malignant histiocytosis and was treated with Cladribine. After drug was administered, patient experienced the following side effects: rash What is  rash. Cladribine dosage: 5MG IV OVER 1H FOR 5 DAYS. Patient recovered.



Cladribine Side Effects Report #4647294-5
Physician from reported Cladribine side effect on Apr 26, 2005. Male patient, 42 years of age, was treated with Cladribine. After drug was administered, patient experienced the following side effects: atrioventricular block complete. Cladribine dosage: unknown. During the same period patient was treated with INTERFERON. Patient was hospitalized. Patient recovered.



Cladribine Side Effects Report #4649645-4
Cladribine side effect was reported by a Physician from on Apr 28, 2005. Male patient, 68 years of age, was diagnosed with lymphoma What is  lymphoma and was treated with Cladribine. After drug was administered, patient experienced the following side effects: myelodysplastic syndrome. Cladribine dosage: unknown. Patient recovered.



Cladribine Side Effects Report #4723711-7
Physician from JAPAN reported Cladribine side effect on July 11, 2005. Male patient, 33 years of age, weighting 143.3 lb, was diagnosed with b-cell lymphoma and was treated with Cladribine. After drug was administered, patient experienced the following side effects: myelodysplastic syndrome. Cladribine dosage: unknown. During the same period patient was treated with BLEOMYCIN, CYCLOPHOSPHAMIDE, CYTARABINE, DOXORUBICIN HYDROCHLORIDE, IFOSFAMIDE, MELPHALAN, METHOTREXATE. Patient died.



Cladribine Side Effects Report #4723713-0
Cladribine side effect was reported by a Physician from JAPAN on July 11, 2005. Male patient, 68 years of age, weighting 118.6 lb, was diagnosed with b-cell lymphoma and was treated with Cladribine. After drug was administered, patient experienced the following side effects: aspergillosis, cerebral haemorrhage, disseminated intravascular coagulation, interstitial lung disease, malaise, pancytopenia, performance status decreased. Cladribine dosage: unknown. Patient died on 08/30/1997.




Cladribine Side Effects Report #4723714-2
Physician from JAPAN reported Cladribine side effect on July 11, 2005. Male patient, 32 years of age, weighting 129.2 lb, was diagnosed with mycosis fungoides, b-cell lymphoma and was treated with Cladribine. After drug was administered, patient experienced the following side effects: follicle centre lymphoma, follicular grade i, ii, iii refractory, gastrointestinal haemorrhage, herpes simplex What is  herpes simplex, malignant neoplasm progression, pancytopenia. Cladribine dosage: unknown. Patient died on 08/01/1998.



Cladribine Side Effects Report #4723715-4
Cladribine side effect was reported by a Physician from JAPAN on July 11, 2005. Male patient, 56 years of age, weighting 176.4 lb, was diagnosed with b-cell lymphoma and was treated with Cladribine. After drug was administered, patient experienced the following side effects: heart rate decreased, ventricular extrasystoles. Cladribine dosage: unknown. Patient recovered.



Cladribine Side Effects Report #4723716-6
Physician from JAPAN reported Cladribine side effect on July 11, 2005. Male patient, 49 years of age, weighting 140.7 lb, was diagnosed with b-cell lymphoma and was treated with Cladribine. After drug was administered, patient experienced the following side effects: myelodysplastic syndrome. Cladribine dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISONE, VINCRISTINE SULPHATE. Patient recovered.



Cladribine Side Effects Report #4723717-8
Cladribine side effect was reported by a Physician from JAPAN on July 11, 2005. Female patient, 41 years of age, weighting 112.4 lb, was diagnosed with mycosis fungoides and was treated with Cladribine. After drug was administered, patient experienced the following side effects: myelodysplastic syndrome, refractory anaemia. Cladribine dosage: unknown. Patient recovered.



Cladribine Side Effects Report #4723718-X
Physician from JAPAN reported Cladribine side effect on July 11, 2005. Male patient, 71 years of age, weighting 138.9 lb, was diagnosed with mantle cell lymphoma and was treated with Cladribine. After drug was administered, patient experienced the following side effects: herpes zoster, myelodysplastic syndrome. Cladribine dosage: unknown. Patient recovered.




Cladribine Side Effects Report #4723719-1
Cladribine side effect was reported by a Physician from JAPAN on July 11, 2005. Female patient, 26 years of age, weighting 99.65 lb, was diagnosed with b-cell lymphoma and was treated with Cladribine. After drug was administered, patient experienced the following side effects: cystitis haemorrhagic, hydronephrosis, pancytopenia, pyelonephritis. Cladribine dosage: unknown. Patient recovered.



Cladribine Side Effects Report #4797077-0
Pharmacist from UNITED STATES reported Cladribine side effect on Oct 11, 2005. Female patient, 84 years of age, weighting 154.3 lb, was diagnosed with hairy cell leukaemia, sepsis What is  sepsis and was treated with Cladribine. After drug was administered, patient experienced the following side effects: dialysis What is  dialysis, nephritis allergic, nephritis interstitial, pyrexia, rash What is  rash, renal failure acute. Cladribine dosage: 6 MG DAILY IV. During the same period patient was treated with CEFEPIME, TOBRAMYCIN, VANCOMYCIN, ATENOLOL, INDAPAMIDE, ASPIRIN. Patient recovered.



Cladribine Side Effects Report #4836134-7
Cladribine side effect was reported by a Physician from JAPAN on Nov 14, 2005. Female patient was diagnosed with mantle cell lymphoma and was treated with Cladribine. After drug was administered, patient experienced the following side effects: renal failure, tumour lysis syndrome. Cladribine dosage: 0.2 MG/KG/DAY ON DAYS 2-6. During the same period patient was treated with RITUXIMAB, MITOXANTRONE. Patient died.



Cladribine Side Effects Report #4890874-2
Health Professional from POLAND reported Cladribine side effect on Jan 13, 2006. Female patient, 51 years of age, was treated with Cladribine. After drug was administered, patient experienced the following side effects: neuroendocrine carcinoma of the skin. Cladribine dosage: unknown. During the same period patient was treated with RITUXIMAB, VINCRISTINE, DOXORUBICIN, PREDNISONE, CYCLOPHOSPHAMIDE. Patient recovered.



Cladribine Side Effects Report #4890875-4
Cladribine side effect was reported by a Health Professional from IRELAND on Jan 13, 2006. Male patient, 36 years of age, was treated with Cladribine. After drug was administered, patient experienced the following side effects: myelodysplastic syndrome. Cladribine dosage: unknown. Patient recovered.




Cladribine Side Effects Report #4932886-6
Physician from JAPAN reported Cladribine side effect on Feb 20, 2006. Female patient, weighting 93.26 lb, was diagnosed with hairy cell leukaemia, sepsis What is  sepsis and was treated with Cladribine. After drug was administered, patient experienced the following side effects: fall What is  fall, femur fracture, hairy cell leukaemia, pancytopenia, sepsis What is  sepsis. Cladribine dosage: unknown. During the same period patient was treated with ACYCLOVIR, CEFOZOPRAN HYDROCHLORIDE. Patient was hospitalized. Patient died on 09/30/2005.



Cladribine Side Effects Report #4957705-3
Cladribine side effect was reported by a Physician from UNITED STATES on Mar 17, 2006. Male patient, 56 years of age, weighting 262.0 lb, was diagnosed with multiple sclerosis What is  multiple sclerosis and was treated with Cladribine. After drug was administered, patient experienced the following side effects: hepatic enzyme increased, metastases to liver, oesophageal carcinoma. Cladribine dosage: unknown. During the same period patient was treated with NOVANTRONE, COPAXONE. Patient was hospitalized. Patient recovered.



Cladribine Side Effects Report #4964337-X
Physician from UNITED STATES reported Cladribine side effect on Mar 29, 2006. Male patient, 60 years of age, was treated with Cladribine. After drug was administered, patient experienced the following side effects: chromosomal deletion, diverticular perforation, fungal infection What is  fungal infection, herpes zoster, operative haemorrhage, pancytopenia, pemphigus What is  pemphigus, pseudomonas infection, staphylococcal impetigo. Cladribine dosage: unknown. Patient was hospitalized. Patient died on 06/01/2003.



Cladribine Side Effects Report #4967308-2
Cladribine side effect was reported by a Health Professional from AUSTRALIA on Mar 27, 2006. Female patient, 74 years of age, was treated with Cladribine. After drug was administered, patient experienced the following side effects: hypoxia, lobar pneumonia, lung infiltration, neutropenic sepsis, waldenstrom's macroglobulinaemia refractory. Cladribine dosage: unknown. Patient died.



Cladribine Side Effects Report #4967309-4
Health Professional from AUSTRALIA reported Cladribine side effect on Mar 27, 2006. Male patient, 77 years of age, was treated with Cladribine. After drug was administered, patient experienced the following side effects: diffuse large b-cell lymphoma, listeriosis, tuberculosis What is  tuberculosis. Cladribine dosage: unknown. Patient died.





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