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Clofarabine Side Effects summary

Total Clofarabine reports: 311.
Clofarabine FDA safety alerts: No.
Reported deaths: 120    Reported hospitalizations: 220.
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Clofarabine Side Effects: febrile neutropenia, hypotension, diarrhoea, blood culture positive, bone marrow failure, neutropenia, alanine aminotransferase increased, sepsis, bacterial infection, disease progression, renal failure,
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Clofarabine Side Effects reported to FDA

Showing 1-40 of 311 Next >

Clofarabine Side Effects Report #5637705-0
Physician from UNITED STATES reported CLOFARABINE problem on Feb 15, 2008. Female patient, 24 years of age, weighting 172.4 lb, was diagnosed with myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: acidosis, anaemia, asthenia, bacterial infection, cough, diarrhoea, fatigue, fluid overload, headache. CLOFARABINE dosage: 75 MG, QDX5, INTRAVENOUS. During the same period patient was treated with CYTARABINE. Patient was hospitalized. Patient recovered.



Clofarabine Side Effects Report #5637768-2
CLOFARABINE problem was reported by a Health Professional from UNITED STATES on Feb 13, 2008. Male patient, 67 years of age, was diagnosed with acute myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: acute respiratory failure, bone marrow failure, confusional state, hypotension, hypoxia, lung infection, pneumonia. CLOFARABINE dosage: 39 MG, QDX5, INTRAVENOUS. During the same period patient was treated with IDARUBICIN, CYTARABINE, PANTOPRAZOLE, AZTREONAM, CLINDAMYCIN, ZYVOX, DILAUDID, SENOKOT. Patient was hospitalized. Patient recovered.



Clofarabine Side Effects Report #5640763-0
Physician from UNITED STATES reported CLOFARABINE problem on Feb 11, 2008. Female patient, 70 years of age, weighting 200.2 lb, was diagnosed with myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: aspiration bone marrow abnormal, bacteraemia, bacterial infection, blood culture positive, blood lactate dehydrogenase increased, bronchoalveolar lavage abnormal, bronchoscopy abnormal, candidiasis, cardiomegaly. CLOFARABINE dosage: 38 MG, QDX5, INTRAVEOUS : 0, QDX5, INTRAVENOUS. During the same period patient was treated with TIGECYCLINE, DIFLUCAN, VANCOMYCIN, VORICONAZOLE, AZITHROMYCIN. Patient was hospitalized. Patient recovered.



Clofarabine Side Effects Report #5641954-5
CLOFARABINE problem was reported by a Health Professional from UNITED KINGDOM on Feb 14, 2008. Female patient, 66 years of age, was diagnosed with myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: venous thrombosis. CLOFARABINE dosage: unknown. During the same period patient was treated with DAUNORUBICIN. Patient was hospitalized. Patient recovered.




Clofarabine Side Effects Report #5644403-6
Health Professional from UNITED STATES reported CLOFARABINE problem on Feb 21, 2008. Male patient, 70 years of age, weighting 180.8 lb, was diagnosed with acute leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: ascites, blood bilirubin increased, calcinosis, cheyne-stokes respiration, cholelithiasis, hepatomegaly, neutropenia, pancytopenia, pleural effusion. CLOFARABINE dosage: 35 MG, QDX5, ORAL. During the same period patient was treated with LEVAQUIN, DIFLUCAN, METFORMIN, OMEPRAZOLE, EXJADE, METOPROLOL SUCCINATE, ALPRAZOLAM, TORSEMIDE. Patient was hospitalized. Patient died on 02/19/2008.



Clofarabine Side Effects Report #5644405-X
CLOFARABINE problem was reported by a Physician from UNITED STATES on Feb 14, 2008. Female patient, child 5 years of age, weighting 27.12 lb, was diagnosed with acute lymphocytic leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: abdominal distension, anorectal discomfort, arthropathy, ascites, blast cells present, bronchial disorder, caecitis, cellulitis, disease progression. CLOFARABINE dosage: 18 MG, QDX5, INTRAVENOUS; 18MG, QD, INTRAVENOUS, 18 MG, QD, INTRAVENOUS. During the same period patient was treated with ETOPOSIDE, CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient died on 02/09/2007.



Clofarabine Side Effects Report #5646790-1
Physician from UNITED KINGDOM reported CLOFARABINE problem on Feb 18, 2008. Female patient, 76 years of age, was diagnosed with acute myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: hepatic fibrosis, pneumonia. CLOFARABINE dosage: 35 MG, QDX5, INTRAVENOUS. During the same period patient was treated with GLICLAZIDE, METFORMIN, QUINE SULPHATE, ACARBOSE, TIMOLOL MALEATE. Patient died on 01/26/2008.



Clofarabine Side Effects Report #5647927-0
CLOFARABINE problem was reported by a Physician from UNITED STATES on Feb 22, 2008. Male patient, 67 years of age, was diagnosed with acute myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: acute respiratory failure, bone marrow failure, confusional state, hypotension, lung infection. CLOFARABINE dosage: 39 MG, QDX5, INTRAVENOUS. During the same period patient was treated with IDARUBICIN, CYTARABINE, PANTOPRAZOLE, AZTREONAM, CLINDAMYCIN, ZYVOX, DILAUDID, SENOKOT. Patient was hospitalized. Patient recovered.



Clofarabine Side Effects Report #5648914-9
Physician from UNITED KINGDOM reported CLOFARABINE problem on Feb 18, 2008. Male patient, 70 years of age, was diagnosed with acute myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: neutropenia, thrombocytopenia. CLOFARABINE dosage: unknown. Patient recovered.




Clofarabine Side Effects Report #5587639-5
CLOFARABINE problem was reported by a Physician from UNITED STATES on Jan 02, 2008. Male patient, 60 years of age, weighting 237.7 lb, was diagnosed with acute myeloid leukaemia recurrent and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: anaphylactic reaction, azotaemia, blister, coma, dermatitis bullous, dialysis, febrile neutropenia, fungus serology test positive, gastrointestinal haemorrhage. CLOFARABINE dosage: unknown. During the same period patient was treated with CYTARABINE, OCTREOTIDE ACETATE, MORPHINE, HYDROCORTISONE, CEFEPIME, ZOLOFT, TRIAMCINOLONE, PREGABALIN. Patient was hospitalized. Patient died on 11/20/2007.



Clofarabine Side Effects Report #5594144-9
Physician from UNITED STATES reported CLOFARABINE problem on Jan 08, 2008. Female patient, 41 years of age, was diagnosed with acute myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: bone marrow failure, eye pain, febrile neutropenia, headache, meningeal disorder, subcutaneous abscess, visual acuity reduced, visual disturbance. CLOFARABINE dosage: 22.5 MG/M2, QDX5, INTRAVENOUS. During the same period patient was treated with IDARUBICIN, ACETAMINOPHEN, ALNAGEL, CASPOFUNGIN ACETATE, DAPTOMYCIN, ANTUSSIN, DIPHENHYDRAMINE, DIPHENOXYLATE. Patient was hospitalized. Patient recovered.



Clofarabine Side Effects Report #5597529-X
CLOFARABINE problem was reported by a Physician from UNITED STATES on Jan 03, 2008. Female patient, 71 years of age, was diagnosed with acute myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood creatinine increased, blood magnesium decreased, blood potassium decreased, blood sodium decreased, blood urea increased, carbon dioxide decreased. CLOFARABINE dosage: 30 MG/M2, QD, INTRAVENOUS; 20 MG/M2, QD, INTRAVENOUS. During the same period patient was treated with BENAZEPRIL, MECLOZINE, LOVASTATIN, MEGACE, ZANTAC, PHENYTOIN. Patient was hospitalized. Patient recovered.



Clofarabine Side Effects Report #5599285-8
Health Professional from UNITED STATES reported CLOFARABINE problem on Jan 11, 2008. Male patient, 67 years of age, was diagnosed with acute myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: acute respiratory failure, back pain, bone marrow failure, hypotension, lung infection, pneumonia. CLOFARABINE dosage: 39 MG, QDX5, INTRAVENOUS. During the same period patient was treated with IDARUBICIN, CYTARABINE, PANTOPRAZOLE, AZTREONAM, CLINDAMYCIN, ZYVOX, DILAUDID, SENOKOT. Patient was hospitalized. Patient recovered.



Clofarabine Side Effects Report #5599286-X
CLOFARABINE problem was reported by a Health Professional from UNITED STATES on Jan 09, 2008. Female patient, child 7 years of age, weighting 77.16 lb, was diagnosed with acute lymphocytic leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: aspergillosis, atelectasis, bacterial infection, bone marrow failure, bradycardia, central line infection, convulsion, febrile neutropenia, haematocrit decreased. CLOFARABINE dosage: 47 MG, QDX5, INTRAVNEOUS. During the same period patient was treated with ETOPOSIDE, CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient died on 01/07/2008.




Clofarabine Side Effects Report #5601151-6
Health Professional from UNITED STATES reported CLOFARABINE problem on Jan 22, 2008. Male patient, weighting 194.0 lb, was diagnosed with stem cell transplant and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: aortic dilatation, lobar pneumonia, oxygen saturation decreased, parainfluenzae virus infection, pleural effusion, pulmonary embolism, tachypnoea. CLOFARABINE dosage: 84 MG/ 20 MG DAILY IV DRIP. During the same period patient was treated with MELPHALAN. Patient was hospitalized. Patient recovered.



Clofarabine Side Effects Report #5603614-6
CLOFARABINE problem was reported by a Health Professional from UNITED STATES on Jan 14, 2008. Female patient, 48 years of age, weighting 114.6 lb, was diagnosed with acute myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: cytomegalovirus viraemia, platelet count decreased. CLOFARABINE dosage: unknown. During the same period patient was treated with BUSULFAN. Patient was hospitalized. Patient recovered.



Clofarabine Side Effects Report #5604873-6
Physician from UNITED STATES reported CLOFARABINE problem on Jan 16, 2008. Male patient, 67 years of age, was diagnosed with acute myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: acute respiratory failure, back pain, bone marrow failure, confusional state, hypotension, lung infection, pneumonia. CLOFARABINE dosage: 39 MG, QDX5, INTRAVENOUS. During the same period patient was treated with IDARUBICIN, CYTARABINE, PANTOPRAZOLE, AZTREONAM, CLINDAMYCIN, ZYVOX, DILAUDID, SENOKOT. Patient was hospitalized. Patient recovered.



Clofarabine Side Effects Report #5610401-1
CLOFARABINE problem was reported by a Consumer or non-health professional from UNITED STATES on Dec 05, 2007. Female patient, child 9 years of age, weighting 55.56 lb, was diagnosed with acute lymphocytic leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: anorexia, atelectasis, blood disorder, bone marrow transplant, cytomegalovirus infection, depression, epistaxis, febrile neutropenia, herpes virus infection. CLOFARABINE dosage: 30 MG/M2 IV. During the same period patient was treated with ETOPOSIDE. Patient was hospitalized. Patient recovered.



Clofarabine Side Effects Report #5610402-3
Physician from UNITED STATES reported CLOFARABINE problem on Jan 21, 2008. Male patient, 67 years of age, weighting 172.4 lb, was diagnosed with bone marrow conditioning regimen and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: aspartate aminotransferase increased, blood bilirubin increased, blood stem cell transplant failure, dialysis, liver function test abnormal, mucosal inflammation, nausea, neutropenic infection, renal failure acute. CLOFARABINE dosage: 54 MG, QDX5, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, METHOTREXATE. Patient was hospitalized. Patient recovered.




Clofarabine Side Effects Report #5610944-0
CLOFARABINE problem was reported by a Health Professional from UNITED STATES on Jan 15, 2008. Female patient, 70 years of age, was diagnosed with acute myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: acidosis, acute respiratory distress syndrome, bronchitis, confusional state, depressed level of consciousness, disorientation, encephalopathy, fall, hyponatraemia. CLOFARABINE dosage: 30 MG/M2, QDX5, INTRAVENOUS. During the same period patient was treated with BENADRYL, AMBIEN, ACYCLOVIR, ALLOPURINOL, AMLODIPINE, CALCIUM GLUCONATE, CEFEPIME, DOCUSATE. Patient was hospitalized. Patient died on 03/19/2007.



Clofarabine Side Effects Report #5614673-9
Physician from UNITED STATES reported CLOFARABINE problem on Jan 23, 2008. Male patient, 67 years of age, weighting 189.6 lb, was diagnosed with myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: acute myeloid leukaemia, adenoma benign, aggression, aspiration, atelectasis, biopsy bone marrow abnormal, cerebral calcification, deep vein thrombosis, depressed level of consciousness. CLOFARABINE dosage: 30 MG/M2, INTRAVENOUS. During the same period patient was treated with ACETAMINOPHEN, LOVENOX, TOBRAMYCIN, VANCOMYCIN, DOUBUTAMINE, ALBUMIN, NOREPINEPHRINE BITARTRATE, MEROPENEM. Patient was hospitalized. Patient recovered.



Clofarabine Side Effects Report #5614856-8
CLOFARABINE problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Jan 17, 2008. Female patient, 74 years of age, was diagnosed with acute myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: acute febrile neutrophilic dermatosis, rash maculo-papular. CLOFARABINE dosage: unknown. Patient recovered.



Clofarabine Side Effects Report #5534998-5
Physician from UNITED STATES reported CLOFARABINE problem on Nov 21, 2007. Male patient, 60 years of age, weighting 237.4 lb, was diagnosed with myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: anaphylactic reaction, dermatitis bullous, dialysis, febrile neutropenia, gastrointestinal haemorrhage, mental status changes, pain, rash erythematous, renal failure acute. CLOFARABINE dosage: 90 MG DAILY IV. During the same period patient was treated with CYTARABINE. Patient was hospitalized. Patient recovered.



Clofarabine Side Effects Report #5534999-7
CLOFARABINE problem was reported by a Physician from UNITED STATES on Nov 26, 2007. Female patient, 46 years of age, was diagnosed with acute myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: aggression, agitation, bipolar disorder, condition aggravated, cytomegalovirus test positive, hallucination, pleural effusion, pneumonitis, stem cell transplant. CLOFARABINE dosage: 188 MG DAILY IV. During the same period patient was treated with FLUDARABINE PHOSPHATE, BUSULFAN. Patient was hospitalized. Patient recovered.



Clofarabine Side Effects Report #5535328-5
Health Professional from UNITED STATES reported CLOFARABINE problem on Nov 28, 2007. Female patient, child 7 years of age, weighting 66.58 lb, was diagnosed with acute lymphocytic leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: abdominal pain, alanine aminotransferase increased, anxiety, aspartate aminotransferase increased, back pain, bk virus infection, bladder spasm, chest pain, constipation. CLOFARABINE dosage: 40 MG QD X 5 IV. During the same period patient was treated with CYTARABINE. Patient was hospitalized. Patient recovered.



Clofarabine Side Effects Report #5538366-1
CLOFARABINE problem was reported by a Health Professional from UNITED STATES on Nov 26, 2007. Female patient, 15 years of age, weighting 207.9 lb, was diagnosed with acute lymphocytic leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: acidosis, anxiety, ascites, bacteraemia, blood albumin decreased, blood alkaline phosphatase increased, blood amylase decreased, blood bilirubin increased, blood culture positive. CLOFARABINE dosage: 80 MG QD IV. During the same period patient was treated with ETOPOSIDE, CYCLOPHOSPHAMIDE, ACETAMINOPHEN, ACYCLOVIR, ALLOPURINOL, AMIKACIN, CALCITRIOL, CHLOROTHIAZIDE. Patient died on 11/21/2007.



Clofarabine Side Effects Report #5538367-3
Physician from UNITED STATES reported CLOFARABINE problem on Nov 29, 2007. Female patient, 21 years of age, weighting 150.1 lb, was diagnosed with acute lymphocytic leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: aspergillosis, blood amylase abnormal, bradycardia, diabetic ketoacidosis, glucose tolerance impaired, headache, hyperbilirubinaemia, hypotension, lipase abnormal. CLOFARABINE dosage: 40 MG/M2 QD X 3;IV. During the same period patient was treated with CYCLOPHOSPHAMIDE, ZOFRAN, ALLOPURINOL, CEFEPIME, HALOPERIDOL, HYDRALAZINE, HYDROMORPHONE. Patient was hospitalized. Patient died on 11/27/2007.



Clofarabine Side Effects Report #5542874-7
CLOFARABINE problem was reported by a Health Professional from UNITED STATES on Nov 29, 2007. Female patient, 68 years of age, weighting 190.3 lb, was diagnosed with acute myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: abdominal distension, abdominal tenderness, anaemia, dyspnoea, gastrointestinal haemorrhage. CLOFARABINE dosage: 57.6 MG QD IV. Patient recovered.



Clofarabine Side Effects Report #5549610-9
Physician from UNITED STATES reported CLOFARABINE problem on Dec 04, 2007. Male patient, weighting 153.0 lb, was diagnosed with acute myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: acute respiratory distress syndrome, infection, intracranial haematoma, left ventricular dysfunction, platelet count abnormal, post procedural haemorrhage, pulmonary hypertension, tricuspid valve incompetence. CLOFARABINE dosage: unknown. Patient was hospitalized. Patient recovered.



Clofarabine Side Effects Report #5549662-6
CLOFARABINE problem was reported by a Health Professional from UNITED STATES on Dec 04, 2007. Female patient, child 7 years of age, weighting 66.58 lb, was diagnosed with acute lymphocytic leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: abdominal pain, alanine aminotransferase increased, anorexia, aspartate aminotransferase increased, back pain, bk virus infection, bladder spasm, blood pressure increased, chest pain. CLOFARABINE dosage: 40 MG QD X 5 IV. During the same period patient was treated with CYTARABINE. Patient was hospitalized. Patient recovered.



Clofarabine Side Effects Report #5549670-5
Physician from UNITED STATES reported CLOFARABINE problem on Dec 03, 2007. Male patient, 39 years of age, was diagnosed with bone marrow conditioning regimen and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: abdominal distension, catheter sepsis, catheter site erythema, catheter site pain, confusional state, diarrhoea, enterococcal infection, graft versus host disease. CLOFARABINE dosage: 20 MG/M2 QD IV. During the same period patient was treated with MELPHALAN, THIOTEPA, VANCOMYCIN, MYCOPHENOLATE MOFETIL, IPRATROPIUM, LEVOFLOXACIN, FILGRASTIM. Patient was hospitalized. Patient died on 07/22/2007.



Clofarabine Side Effects Report #5553714-4
CLOFARABINE problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 29, 2007. Male patient, weighting 220.5 lb, was diagnosed with myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: anxiety, atelectasis, blood chloride increased, bronchoalveolar lavage abnormal, cardiac failure, cold sweat, confusional state, feeling cold, fluid overload. CLOFARABINE dosage: unknown. During the same period patient was treated with TYLENOL, ATIVAN, LASIX, PANTOPRAZOLE, ATENOLOL, AMLODIPINE, VALSARTAN. Patient recovered.



Clofarabine Side Effects Report #5562700-X
Health Professional from UNITED STATES reported CLOFARABINE problem on Dec 11, 2007. Male patient, weighting 189.6 lb, was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: metastatic neoplasm, subdural haematoma. CLOFARABINE dosage: 84 MG DAILY IV DRIP. During the same period patient was treated with CAMPATH. Patient recovered.



Clofarabine Side Effects Report #5564521-0
CLOFARABINE problem was reported by a Health Professional from UNITED STATES on Dec 07, 2007. Female patient, 41 years of age, was diagnosed with acute myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: bone marrow failure, febrile neutropenia, infection, subcutaneous abscess. CLOFARABINE dosage: 22.5 MG/M2 QD X 5 IV. During the same period patient was treated with IDARUBICIN, ACETAMINOPHEN, ALUMINUM AND MAGNESIUM HYDROXIDE AND SIMETHICONE, CASPOFUNGIN ACETATE, DAPTOMYCIN, DEXTROMETHORPHAN, DIPHENHYDRAMINE, DIPHENOXYLATE. Patient was hospitalized. Patient recovered.



Clofarabine Side Effects Report #5565796-4
Physician from UNITED STATES reported CLOFARABINE problem on Nov 30, 2007. Female patient, 20 years of age, weighting 142.2 lb, was diagnosed with acute lymphocytic leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: abdominal pain lower, alanine aminotransferase increased, aspartate aminotransferase increased, bacillus infection, back pain, blood alkaline phosphatase increased, blood bilirubin increased, blood chloride increased, blood culture positive. CLOFARABINE dosage: 75 MG QD X 5, IV. During the same period patient was treated with ETOPOSIDE, CYCLOPHOSPHAMIDE, NOREPINEPHRINE, VANCOMYCIN. Patient was hospitalized. Patient recovered.



Clofarabine Side Effects Report #5565799-X
CLOFARABINE problem was reported by a Physician from UNITED STATES on Dec 07, 2007. Female patient, 49 years of age, was diagnosed with acute myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: bone marrow failure. CLOFARABINE dosage: 11.5 MG/M2 GQ X 5; IV. During the same period patient was treated with PRILOSEC, SYNTHROID, WELLBUTRIN, ACYCLOVIR, VANTIN, ITRACONAZOLE, ATARAX, DARVON. Patient recovered.



Clofarabine Side Effects Report #5566519-5
Physician from UNITED STATES reported CLOFARABINE problem on Dec 05, 2007. Female patient, 66 years of age, weighting 210.3 lb, was diagnosed with acute myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: blood pressure diastolic decreased, body temperature decreased, diarrhoea, renal failure acute, respiratory rate increased. CLOFARABINE dosage: 66 MG QD X 5 IV. During the same period patient was treated with ESTRADIOL, SYNTHROID, LIPITOR, METOPROLOL, AMIKACIN, PROTONIX, VALTREX. Patient was hospitalized. Patient recovered.



Clofarabine Side Effects Report #5566522-5
CLOFARABINE problem was reported by a Physician from UNITED STATES on Dec 10, 2007. Female patient, 46 years of age, weighting 117.1 lb, was diagnosed with acute myeloid leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: aggression, agitation, bipolar disorder, condition aggravated, cytomegalovirus test positive, hallucination, pleural effusion, pneumonia, pneumonitis. CLOFARABINE dosage: 30 MG/M2 IV. During the same period patient was treated with FLUDARABINE PHOSPHATE, BUSULFAN. Patient was hospitalized. Patient recovered.



Clofarabine Side Effects Report #5568011-0
Physician from UNITED STATES reported CLOFARABINE problem on Dec 07, 2007. Male patient, 16 years of age, weighting 85.98 lb, was diagnosed with acute lymphocytic leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, hyperbilirubinaemia, renal failure, respiratory failure. CLOFARABINE dosage: 30 MG/M2 QD IV. During the same period patient was treated with CYCLOPHOSPHAMIDE, ACETAMINOPHEN, ALLOPURINOL, HYDROCORTISONE. Patient died on 05/13/2007.



Clofarabine Side Effects Report #5569900-3
CLOFARABINE problem was reported by a Consumer or non-health professional from UNITED STATES on Dec 05, 2007. Female patient, child 9 years of age, weighting 55.56 lb, was diagnosed with acute lymphocytic leukaemia and was treated with CLOFARABINE. After drug was administered, patient experienced the following problems/side effects: anorexia,