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Clonazepam Side Effects

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Common Clonazepam Side Effects


The most commonly reported Clonazepam side effects (click to view or check a box to report):

Completed Suicide (405)
Death (302)
Toxicity To Various Agents (290)
Cardiac Arrest (268)
Respiratory Arrest (250)
Cardio-respiratory Arrest (145)
Anxiety (141)
Dizziness (112)
Overdose (108)
Headache (93)
Somnolence (91)
Convulsion (83)
Poisoning (81)
Nausea (75)
Depression (74)
Confusional State (73)
Fatigue (70)
Agitation (69)
Insomnia (67)
Pain (64)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Clonazepam Side Effects Reported to FDA



Clonazepam Side Effect Report#9972229
Angina Pectoris, Transient Ischaemic Attack, Eye Movement Disorder, Eye Disorder, Hypoaesthesia
This is a report of a 65-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: panic disorder,post-traumatic stress disorder, who was treated with Clonazepam 0.5 Teva (dosage: Take 1/4 Tablet, start time:
Aug 05, 2013), combined with: NA. and developed a serious reaction and side effect(s): Angina Pectoris, Transient Ischaemic Attack, Eye Movement Disorder, Eye Disorder, Hypoaesthesia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Clonazepam 0.5 Teva treatment in female patients, resulting in Angina Pectoris side effect. The patient was hospitalized and became disabled.
Clonazepam Side Effect Report#9940484
Hepatotoxicity, Convulsion
This report suggests a potential Clonazepam Hepatotoxicity side effect(s) that can have serious consequences. A 7-year-old female patient (weight: NA) from TR was diagnosed with the following symptoms/conditions: NA and used Clonazepam (dosage: 0.05 Mg/kg/day) starting NS. After starting Clonazepam the patient began experiencing various side effects, including: Hepatotoxicity, ConvulsionAdditional drugs used concurrently:
  • Oxcarbazepine (22 Mg/kg/day)
The patient was hospitalized. Although Clonazepam demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Hepatotoxicity, may still occur.
Clonazepam Side Effect Report#9922416
Cognitive Disorder, Amnesia, Emotional Disorder, Tinnitus, Panic Attack, Muscle Spasms, Migraine, Depersonalisation
This Cognitive Disorder problem was reported by a consumer or non-health professional from US. A 44-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: insomnia,anxiety. On NS this consumer started treatment with Clonazepam (dosage: 2 Pills Five Times A Day). The following drugs were being taken at the same time: NA. When using Clonazepam, the patient experienced the following unwanted symptoms/side effects: Cognitive Disorder, Amnesia, Emotional Disorder, Tinnitus, Panic Attack, Muscle Spasms, Migraine, DepersonalisationAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Cognitive Disorder, may become evident only after a product is in use by the general population.
Clonazepam Side Effect Report#9922116
Convulsion, Hepatotoxicity, Liver Function Test Abnormal
This Convulsion side effect was reported by a health professional from TR. A 9-year-old female patient (weight:NA) experienced the following symptoms/conditions: convulsion.The patient was prescribed Clonazepam (drug dosage: 0.05 Mg/kg, Unk), which was initiated on NS. Concurrently used drugs:
  • Oxcarbazepine (22 Mg/kg, Unk)
.After starting to take Clonazepam the consumer reported adverse symptoms, such as: Convulsion, Hepatotoxicity, Liver Function Test AbnormalThese side effects may potentially be related to Clonazepam. The patient was hospitalized.
Clonazepam Side Effect Report#9916842
Abasia, Coordination Abnormal, Depressed Mood, Tension, Dry Mouth
This is a report of a 28-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: anxiety,insomnia, who was treated with Clonazepam 1mg (dosage: Unk, start time:
Feb 12, 2014), combined with: NA. and developed a serious reaction and side effect(s): Abasia, Coordination Abnormal, Depressed Mood, Tension, Dry Mouth after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Clonazepam 1mg treatment in female patients, resulting in Abasia side effect.
Clonazepam Side Effect Report#9900766
Multi-organ Failure, Neuroleptic Malignant Syndrome, Respiratory Failure
This report suggests a potential Clonazepam 0.5 Mg Tablet Multi-organ Failure side effect(s) that can have serious consequences. A 41-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: NA and used Clonazepam 0.5 Mg Tablet (dosage: Unk) starting NS. After starting Clonazepam 0.5 Mg Tablet the patient began experiencing various side effects, including: Multi-organ Failure, Neuroleptic Malignant Syndrome, Respiratory FailureAdditional drugs used concurrently:
  • Lithium Carbonate Tablets, Usp 300mg
  • Clomipramine
  • Lamotrigine
  • Ziprasidone
  • Propofol (Unk)
  • Propofol (Unk)
  • Benztropine
  • Succinylcholine
The patient was hospitalized. Although Clonazepam 0.5 Mg Tablet demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Multi-organ Failure, may still occur.
Clonazepam Side Effect Report#9899409
Neuroleptic Malignant Syndrome, Hyperthermia Malignant
This Neuroleptic Malignant Syndrome problem was reported by a health professional from US. A 41-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Clonazepam (dosage: NA). The following drugs were being taken at the same time:
  • Propofol
  • Propofol
  • Lithium
  • Ziprasidone
  • Suxamethonium Chloride (Single Dose Given)
  • Benzatropine
  • Clomipramine
  • Lamotrigine
When using Clonazepam, the patient experienced the following unwanted symptoms/side effects: Neuroleptic Malignant Syndrome, Hyperthermia MalignantThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Neuroleptic Malignant Syndrome, may become evident only after a product is in use by the general population.
Clonazepam Side Effect Report#9893874
Neuroleptic Malignant Syndrome, Hyperthermia Malignant
This Neuroleptic Malignant Syndrome side effect was reported by a health professional from US. A 41-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Clonazepam (drug dosage: NA), which was initiated on NS. Concurrently used drugs:
  • Lithium
  • Ziprasidone
  • Propofol
  • Propofol
  • Suxamethonium Chloride (Single Dose Given)
  • Benzatropine
  • Clomipramine
  • Lamotrigine
.After starting to take Clonazepam the consumer reported adverse symptoms, such as: Neuroleptic Malignant Syndrome, Hyperthermia MalignantThese side effects may potentially be related to Clonazepam. The patient was hospitalized.
Clonazepam Side Effect Report#9884236
Anxiety, Condition Aggravated
This is a report of a 23-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: anxiety, who was treated with Clonazepam (dosage: NA, start time:
Jan 01, 2014), combined with: NA. and developed a serious reaction and side effect(s): Anxiety, Condition Aggravated after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Clonazepam treatment in female patients, resulting in Anxiety side effect.
Clonazepam Side Effect Report#9880433
Product Substitution Issue
This report suggests a potential Clonazepam Product Substitution Issue side effect(s) that can have serious consequences. A 52-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: NA and used Clonazepam (dosage: NA) starting NS. After starting Clonazepam the patient began experiencing various side effects, including: Product Substitution IssueAdditional drugs used concurrently: NA. Although Clonazepam demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Product Substitution Issue, may still occur.
Clonazepam Side Effect Report#9880343
Product Quality Issue, Product Substitution Issue
This Product Quality Issue problem was reported by a consumer or non-health professional from US. A 69-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: parkinson^s disease,nocturia. On
Jan 07, 2014 this consumer started treatment with Clonazepam 1mg (dosage: 1 Tablet At Bedtime Taken By Mouth). The following drugs were being taken at the same time: NA. When using Clonazepam 1mg, the patient experienced the following unwanted symptoms/side effects: Product Quality Issue, Product Substitution IssueAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Product Quality Issue, may become evident only after a product is in use by the general population.
Clonazepam Side Effect Report#9874913
Product Substitution Issue, Product Quality Issue
This Product Substitution Issue side effect was reported by a consumer or non-health professional from US. A 66-year-old female patient (weight:NA) experienced the following symptoms/conditions: post-traumatic stress disorder.The patient was prescribed Clonazepam (drug dosage: 2x1 Mg.once Daily, Po.), which was initiated on
May 12, 2013. Concurrently used drugs: NA..After starting to take Clonazepam the consumer reported adverse symptoms, such as: Product Substitution Issue, Product Quality IssueThese side effects may potentially be related to Clonazepam.
Clonazepam Side Effect Report#9867429
Arrhythmia, Arthritis, Hyperthermia
This is a report of a 8-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: NA, who was treated with Clonazepam (dosage: NA, start time: NS), combined with:
  • Topiramate
  • Geodon
  • Acthar Gel
and developed a serious reaction and side effect(s): Arrhythmia, Arthritis, Hyperthermia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Clonazepam treatment in female patients, resulting in Arrhythmia side effect.
Clonazepam Side Effect Report#9860546
Loss Of Consciousness, Psychiatric Symptom, Blood Pressure Increased, Anxiety, Electrocardiogram Qt Prolonged, Hypertension, Transaminases Increased, Pre-eclampsia, Protein Urine Present
This report suggests a potential Clonazepam Loss Of Consciousness side effect(s) that can have serious consequences. A 37-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: NA and used Clonazepam (dosage: NA) starting NS. After starting Clonazepam the patient began experiencing various side effects, including: Loss Of Consciousness, Psychiatric Symptom, Blood Pressure Increased, Anxiety, Electrocardiogram Qt Prolonged, Hypertension, Transaminases Increased, Pre-eclampsia, Protein Urine PresentAdditional drugs used concurrently:
  • Paroxetine
  • Quetiapine
  • Fluoxetine
  • Lamotrigine
  • Lorazepam
  • Haloperidol
  • Glyburide
The patient was hospitalized. Although Clonazepam demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Loss Of Consciousness, may still occur.
Clonazepam Side Effect Report#9860159
Myocarditis
This Myocarditis problem was reported by a health professional from TW. A 14-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: convulsion. On NS this consumer started treatment with Clonazepam (dosage: NA). The following drugs were being taken at the same time:
  • Carbamazepine
  • Phenytoin
When using Clonazepam, the patient experienced the following unwanted symptoms/side effects: MyocarditisThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Myocarditis, may become evident only after a product is in use by the general population.
Clonazepam Side Effect Report#9860133
Neuroleptic Malignant Syndrome
This Neuroleptic Malignant Syndrome side effect was reported by a health professional from US. A 41-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Clonazepam (drug dosage: NA), which was initiated on NS. Concurrently used drugs:
  • Benztropine
  • Chlorimipramine
  • Lamotrigine
.After starting to take Clonazepam the consumer reported adverse symptoms, such as: Neuroleptic Malignant SyndromeThese side effects may potentially be related to Clonazepam. The patient was hospitalized.
Clonazepam Side Effect Report#9859575
Loss Of Consciousness, Intentional Overdose, Suicide Attempt, Exposure During Pregnancy
This is a report of a 37-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: NA, who was treated with Clonazepam (dosage: NA, start time: NS), combined with:
  • Fluoxetine
  • Paroxetine
  • Paroxetine
  • Quetiapine Fumarate
  • Lamotrigine
and developed a serious reaction and side effect(s): Loss Of Consciousness, Intentional Overdose, Suicide Attempt, Exposure During Pregnancy after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Clonazepam treatment in female patients, resulting in Loss Of Consciousness side effect. The patient was hospitalized.
Clonazepam Side Effect Report#9850316
Electrocardiogram Qt Prolonged, Mental Status Changes, Depressed Level Of Consciousness, Overdose, Blood Pressure Increased
This report suggests a potential Clonazepam Electrocardiogram Qt Prolonged side effect(s) that can have serious consequences. A 49-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: NA and used Clonazepam (dosage: 100 Mg, Unk) starting NS. After starting Clonazepam the patient began experiencing various side effects, including: Electrocardiogram Qt Prolonged, Mental Status Changes, Depressed Level Of Consciousness, Overdose, Blood Pressure IncreasedAdditional drugs used concurrently:
  • Amitriptyline (700 Mg, Unk)
Although Clonazepam demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Electrocardiogram Qt Prolonged, may still occur.
Clonazepam Side Effect Report#9848103
Cardio-respiratory Arrest
This Cardio-respiratory Arrest problem was reported by a consumer or non-health professional from US. A 42-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Clonazepam (clonazepam) (clonazepam) (dosage: NA). The following drugs were being taken at the same time:
  • Paroxetine Hydrochloride
  • Amitriptyline (amitriptyline)
When using Clonazepam (clonazepam) (clonazepam), the patient experienced the following unwanted symptoms/side effects: Cardio-respiratory ArrestAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Cardio-respiratory Arrest, may become evident only after a product is in use by the general population.
Clonazepam Side Effect Report#9848082
Product Quality Issue, Product Substitution Issue, Pruritus, Urticaria, Rash Morbilliform
This Product Quality Issue side effect was reported by a consumer or non-health professional from US. A 41-year-old female patient (weight:NA) experienced the following symptoms/conditions: anxiety disorder.The patient was prescribed Clonazepam (drug dosage: NA), which was initiated on
Dec 30, 2013. Concurrently used drugs:
  • One A Day
  • Calcium Potassium
.After starting to take Clonazepam the consumer reported adverse symptoms, such as: Product Quality Issue, Product Substitution Issue, Pruritus, Urticaria, Rash MorbilliformThese side effects may potentially be related to Clonazepam.
Clonazepam Side Effect Report#9847552
This is a report of a 56-year-old male patient (weight: NA) from US, suffering from the following health symptoms/conditions: NA, who was treated with Clonazepam (dosage: NA, start time: NS), combined with:
  • Methadone
  • Oxycodone
  • Amphetamine
  • Metoprolol
and developed a serious reaction and side effect(s): after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Clonazepam treatment in male patients, resulting in Death side effect.
Clonazepam Side Effect Report#9844676
This report suggests a potential Clonazepam Death side effect(s) that can have serious consequences. A 58-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: NA and used Clonazepam (dosage: NA) starting NS. After starting Clonazepam the patient began experiencing various side effects, including:Additional drugs used concurrently:
  • Venlafaxine Hydrochloride
  • Heroin
  • Cocaine
  • Sertraline
  • Quinine
Although Clonazepam demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Death, may still occur.
Clonazepam Side Effect Report#9844673
This Death problem was reported by a pharmacist from US. A 55-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Clonazepam (dosage: NA). The following drugs were being taken at the same time:
  • Heroin
  • Butalbital
  • Acetaminophen
When using Clonazepam, the patient experienced the following unwanted symptoms/side effects:Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Death, may become evident only after a product is in use by the general population.
Clonazepam Side Effect Report#9844672
This Death side effect was reported by a pharmacist from US. A 47-year-old male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Clonazepam (drug dosage: NA), which was initiated on NS. Concurrently used drugs:
  • Heroin
  • Quetiapine
  • Cocaine
  • Ethanol
.After starting to take Clonazepam the consumer reported adverse symptoms, such as: These side effects may potentially be related to Clonazepam.
Clonazepam Side Effect Report#9844647
Completed Suicide, Cardio-respiratory Arrest
This is a report of a 40-year-old male patient (weight: NA) from US, suffering from the following health symptoms/conditions: NA, who was treated with Clonazepam (dosage: NA, start time: NS), combined with:
  • Doxepin
  • Heroin
  • Cocaine
  • Diphenhydramine
  • Trihexyphenidyl
and developed a serious reaction and side effect(s): Completed Suicide, Cardio-respiratory Arrest after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Clonazepam treatment in male patients, resulting in Death side effect.


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The appearance of Clonazepam on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

What are common Clonazepam Side Effects for Women?

Women Side EffectsReports
Completed Suicide 178
Toxicity To Various Agents 143
Death 131
Cardiac Arrest 99
Anxiety 89
Respiratory Arrest 88
Dizziness 79
Headache 66
Nausea 60
Cardio-respiratory Arrest 59

What are common Clonazepam Side Effects for Men?

Men Side EffectsReports
Toxicity To Various Agents 145
Completed Suicide 125
Death 118
Cardiac Arrest 79
Respiratory Arrest 73
Cardio-respiratory Arrest 56
Anxiety 50
Overdose 48
Confusional State 35
Somnolence 34

Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Clonazepam reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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    Clonazepam Safety Alerts, Active Ingredients, Usage Information

    NDC0093-0832
    TypeHUMAN PRESCRIPTION DRUG
    Proprietary NameClonazepam
    NameClonazepam
    Dosage FormTABLET
    RouteORAL
    On market since19960918
    LabelerTeva Pharmaceuticals USA Inc
    Active Ingredient(s)CLONAZEPAM
    Strength(s)0.5
    Unit(s)mg/1
    Pharma ClassBenzodiazepine [EPC],Benzodiazepines [Chemical/Ingredient]

    Clonazepam Dosage, Warnings, Usage.

    Side Effects reported to FDA: 2789

    Clonazepam safety alerts: No

    Reported deaths: 1081

    Reported hospitalizations: 751

    Latest Clonazepam clinical trials