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Clotiazepam Side Effects

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Common Clotiazepam Side Effects


The most commonly reported Clotiazepam side effects (click to view or check a box to report):

Eye Pain (3)
Corneal Oedema (3)
Conjunctival Hyperaemia (3)
Fall (3)
Flat Anterior Chamber Of Eye (3)
Transient Ischaemic Attack (3)
Loss Of Consciousness (3)
Mydriasis (3)
Iris Atrophy (3)
Blood Pressure Systolic Decreased (2)
Altered State Of Consciousness (2)
Convulsion (2)
Overdose (2)
Eye Rolling (2)
Hypotension (2)
Intraocular Pressure Increased (1)
Lenticular Opacities (1)
Incorrect Dose Administered (1)
Hyperglycaemia (1)
Intentional Self-injury (1)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Clotiazepam Side Effects Reported to FDA



Clotiazepam Side Effect Report#9311283
Toxicity To Various Agents
This is a report of a 41-year-old female patient (weight: NA) from IT, suffering from the following health symptoms/conditions: NA, who was treated with Clotiazepam (dosage: 20 Ml, Single, start time:
Jan 01, 2013), combined with: NA. and developed a serious reaction and side effect(s): Toxicity To Various Agents after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Clotiazepam treatment in female patients, resulting in Toxicity To Various Agents side effect. The patient was hospitalized and became disabled.
Clotiazepam Side Effect Report#9102931
Intentional Self-injury, Bradykinesia, Hypotension, Bradyphrenia
This report suggests a potential Clotiazepam Intentional Self-injury side effect(s) that can have serious consequences. A 40-year-old female patient (weight: NA) from IT was diagnosed with the following symptoms/conditions: intentional self-injury and used Clotiazepam (dosage: 10 Mg, 1x/day) starting
Feb 05, 2013. After starting Clotiazepam the patient began experiencing various side effects, including: Intentional Self-injury, Bradykinesia, Hypotension, BradyphreniaAdditional drugs used concurrently: NA.The patient was hospitalized. Although Clotiazepam demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Intentional Self-injury, may still occur.
Clotiazepam Side Effect Report#8450446-X
Pyrexia, Rash, Depression, Constipation, Anaemia, White Blood Cell Count Decreased, Hyperglycaemia
This Pyrexia problem was reported by a physician from Japan. A male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Apr 18, 2012 this consumer started treatment with Clotiazepam (dosage: 15 Mg, Uid/qd). The following drugs were being taken at the same time:
  • Loxoprofen /00890702/ (60-120 Mg / Day)
  • Lansoprazole (15 Mg, Uid/qd)
  • Granisetron Hydrochloride (1 Mg, Uid/qd)
  • Erlotinib Hydrochloride (100 Mg, Uid/qd)
  • Gemcitabine (1000 Mg/m2, Uid/qd)
  • Gemcitabine (1000 Mg/m2, Uid/qd)
  • Gemcitabine (1000 Mg/m2, Uid/qd)
  • Loxoprofen /00890702/ (180 Mg, Uid/qd)
When using Clotiazepam, the patient experienced the following unwanted symptoms/side effects: Pyrexia, Rash, Depression, Constipation, Anaemia, White Blood Cell Count Decreased, HyperglycaemiaThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Pyrexia, may become evident only after a product is in use by the general population.
Clotiazepam Side Effect Report#8173728-8
Incorrect Dose Administered, Electrocardiogram Qt Prolonged
This Incorrect Dose Administered side effect was reported by a physician from Japan. A 71-year-old male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Clotiazepam (drug dosage: NA), which was initiated on NS. Concurrently used drugs:
  • Phenobarbital Tab
  • Sertraline Hydrochloride
  • Amiodarone Hcl (11.4 Gm;x1;po; 4gm;x1;po)
.After starting to take Clotiazepam the consumer reported adverse symptoms, such as: Incorrect Dose Administered, Electrocardiogram Qt ProlongedThese side effects may potentially be related to Clotiazepam.
Clotiazepam Side Effect Report#7714911-2
Angle Closure Glaucoma
This is a report of a 71-year-old female patient (weight: NA) from United Kingdom, suffering from the following health symptoms/conditions: depression, who was treated with Clotiazepam (dosage: NA, start time: NS), combined with:
  • Alprazolam (Unk)
  • Maprotiline (Unk)
and developed a serious reaction and side effect(s): Angle Closure Glaucoma after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Clotiazepam treatment in female patients, resulting in Angle Closure Glaucoma side effect.
Clotiazepam Side Effect Report#7555822-5
Suicide Attempt
This report suggests a potential Clotiazepam Suicide Attempt side effect(s) that can have serious consequences. A 26-year-old female patient (weight: NA) from Japan was diagnosed with the following symptoms/conditions: depression and used Clotiazepam (dosage: Daily Dose 5 Mg) starting
Feb 13, 2011. After starting Clotiazepam the patient began experiencing various side effects, including: Suicide AttemptAdditional drugs used concurrently:
  • Paxil
  • Zoloft
  • Sepazon (Daily Dose 2 Mg)
  • Diazepam (Daily Dose 5 Mg)
  • Ajireru
  • Yaz (1 Df, Once)
  • Amoxapine (Daily Dose 25 Mg)
  • Lorazepam
Although Clotiazepam demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Suicide Attempt, may still occur.
Clotiazepam Side Effect Report#7526052-8
Back Pain, Cardiac Failure, Headache, Dyspnoea, Restless Legs Syndrome, Arthralgia, Delirium
This Back Pain problem was reported by a physician from Japan. A female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Sep 18, 2009 this consumer started treatment with Clotiazepam (dosage: NA). The following drugs were being taken at the same time:
  • Theophylline
  • Tracleer (31.25 Mg, Bid)
  • Tracleer (31.25 Mg, Bid)
  • Ambroxol Hydrochloride
  • Antibiotics-resistant Lactic Acid Bacteriae
  • Salbutamol Sulfate
  • Diflucortolone Valerate
  • Tiquizium Bromide
When using Clotiazepam, the patient experienced the following unwanted symptoms/side effects: Back Pain, Cardiac Failure, Headache, Dyspnoea, Restless Legs Syndrome, Arthralgia, DeliriumAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Back Pain, may become evident only after a product is in use by the general population.
Clotiazepam Side Effect Report#7279142-1
Hepatic Function Abnormal
This Hepatic Function Abnormal side effect was reported by a health professional from Japan. A 68-year-old male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Clotiazepam (drug dosage: NA), which was initiated on
Apr 19, 2010. Concurrently used drugs:
  • Fenofibrate
  • Bisoprolol Fumarate
  • Nizatidine
  • Octotiamine
  • Silodosin
.After starting to take Clotiazepam the consumer reported adverse symptoms, such as: Hepatic Function AbnormalThese side effects may potentially be related to Clotiazepam.
Clotiazepam Side Effect Report#6817674-8
Altered State Of Consciousness, Convulsion, Overdose, Vocal Cord Paralysis
This is a report of a 16-year-old female patient (weight: NA) from Japan, suffering from the following health symptoms/conditions: intentional self-injury,depression, who was treated with Clotiazepam (dosage: 100 Mg, Single, start time:
Jun 11, 2010), combined with:
  • Solanax (Unk)
  • Diphenhydramine Hydrochloride (120 Df, Single)
and developed a serious reaction and side effect(s): Altered State Of Consciousness, Convulsion, Overdose, Vocal Cord Paralysis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Clotiazepam treatment in female patients, resulting in Altered State Of Consciousness side effect. The patient was hospitalized.
Clotiazepam Side Effect Report#6810503-8
Altered State Of Consciousness, Convulsion, Overdose
This report suggests a potential Clotiazepam Altered State Of Consciousness side effect(s) that can have serious consequences. A 16-year-old female patient (weight: NA) from Japan was diagnosed with the following symptoms/conditions: intentional self-injury and used Clotiazepam (dosage: 100 Mg, Single) starting
Jun 11, 2010. After starting Clotiazepam the patient began experiencing various side effects, including: Altered State Of Consciousness, Convulsion, OverdoseAdditional drugs used concurrently:
  • Solanax (Unk)
  • Diphenhydramine Hydrochloride (120 Df, Single)
The patient was hospitalized. Although Clotiazepam demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Altered State Of Consciousness, may still occur.
Clotiazepam Side Effect Report#4651061-6
Eye Rolling, Fall, Hypotension, Loss Of Consciousness, Transient Ischaemic Attack
This Eye Rolling problem was reported by a physician from . A 76-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: autonomic nervous system imbalance. On
Aug 28, 2004 this consumer started treatment with Clotiazepam (dosage: 10 Mg, Unk). The following drugs were being taken at the same time:
  • Diovan (80 Mg, Qd)
When using Clotiazepam, the patient experienced the following unwanted symptoms/side effects: Eye Rolling, Fall, Hypotension, Loss Of Consciousness, Transient Ischaemic AttackAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Eye Rolling, may become evident only after a product is in use by the general population.
Clotiazepam Side Effect Report#4641448-X
Blood Pressure Systolic Decreased, Eye Rolling, Fall, Loss Of Consciousness, Transient Ischaemic Attack
This Blood Pressure Systolic Decreased side effect was reported by a physician from . A 76-year-old female patient (weight:NA) experienced the following symptoms/conditions: autonomic nervous system imbalance,hypertension.The patient was prescribed Clotiazepam (drug dosage: 10 Mg, Unk), which was initiated on
Aug 28, 2004. Concurrently used drugs:
  • Diovan (80 Mg, Qd)
.After starting to take Clotiazepam the consumer reported adverse symptoms, such as: Blood Pressure Systolic Decreased, Eye Rolling, Fall, Loss Of Consciousness, Transient Ischaemic AttackThese side effects may potentially be related to Clotiazepam.
Clotiazepam Side Effect Report#4625477-8
Blood Pressure Systolic Decreased, Fall, Loss Of Consciousness, Transient Ischaemic Attack
This is a report of a 76-year-old female patient (weight: NA) from , suffering from the following health symptoms/conditions: NA, who was treated with Clotiazepam (dosage: 5 Mg, Unk, start time:
Aug 24, 2004), combined with:
  • Diovan (80 Mg, Qd)
and developed a serious reaction and side effect(s): Blood Pressure Systolic Decreased, Fall, Loss Of Consciousness, Transient Ischaemic Attack after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Clotiazepam treatment in female patients, resulting in Blood Pressure Systolic Decreased side effect.
Clotiazepam Side Effect Report#4596478-3
Conjunctival Hyperaemia, Corneal Oedema, Eye Pain, Flat Anterior Chamber Of Eye, Intraocular Pressure Increased, Iris Atrophy, Lenticular Opacities, Mydriasis
This report suggests a potential Clotiazepam Conjunctival Hyperaemia side effect(s) that can have serious consequences. A 71-year-old female patient (weight: NA) from was diagnosed with the following symptoms/conditions: depression and used Clotiazepam (dosage: NA) starting
Jan 01, 1996. After starting Clotiazepam the patient began experiencing various side effects, including: Conjunctival Hyperaemia, Corneal Oedema, Eye Pain, Flat Anterior Chamber Of Eye, Intraocular Pressure Increased, Iris Atrophy, Lenticular Opacities, MydriasisAdditional drugs used concurrently:
  • Alprazolam (ngx)
  • Maprotiline Hydrochloride
Although Clotiazepam demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Conjunctival Hyperaemia, may still occur.
Clotiazepam Side Effect Report#4596460-6
Conjunctival Hyperaemia, Corneal Oedema, Eye Pain, Flat Anterior Chamber Of Eye, Iris Atrophy, Mydriasis
This Conjunctival Hyperaemia problem was reported by a health professional from . A 71-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: depression. On
Jan 01, 1996 this consumer started treatment with Clotiazepam (dosage: NA). The following drugs were being taken at the same time:
  • Alprazolam
  • Maprotiline Hydrochloride
When using Clotiazepam, the patient experienced the following unwanted symptoms/side effects: Conjunctival Hyperaemia, Corneal Oedema, Eye Pain, Flat Anterior Chamber Of Eye, Iris Atrophy, MydriasisAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Conjunctival Hyperaemia, may become evident only after a product is in use by the general population.
Clotiazepam Side Effect Report#4590292-0
Conjunctival Hyperaemia, Corneal Oedema, Eye Pain, Flat Anterior Chamber Of Eye, Iris Atrophy, Mydriasis
This Conjunctival Hyperaemia side effect was reported by a health professional from . A 71-year-old female patient (weight:NA) experienced the following symptoms/conditions: depression.The patient was prescribed Clotiazepam (drug dosage: NA), which was initiated on
Jan 01, 1996. Concurrently used drugs:
  • Alprazolam
  • Maprotiline Hydrochloride
.After starting to take Clotiazepam the consumer reported adverse symptoms, such as: Conjunctival Hyperaemia, Corneal Oedema, Eye Pain, Flat Anterior Chamber Of Eye, Iris Atrophy, MydriasisThese side effects may potentially be related to Clotiazepam.



The appearance of Clotiazepam on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

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Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Clotiazepam reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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    Side Effects reported to FDA: 16

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    Reported hospitalizations: 6

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