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Mucus In Stool (6)
Edema Of Feet (5)
Combined With Lexapro (4)
Blurred Visison (3)
Fluid Retention (2)
Not Sleeping (2)
Nausea (1)
>>View All User Submitted Colace Side Effects

Colace Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 172 

Rash, Pyrexia, Nausea, Glossodynia, Chest Pain, Hot Flush (8272149-7)
on Feb 15, 2012 Female from UNITED STATES , 34 years of age, was treated with Colace. Directly after, patient experienced the unwanted or unexpected Colace side effects: rash, pyrexia, nausea, glossodynia, chest pain, hot flush. Colace dosage: N/A.
Associated medications used:
  • Levothyroxine Sodium
  • Prochlorperazine Maleate
  • Vandetanib
  • Codeine Phosphate And Acetaminophen
  • Oxycodone Hcl


Rectal Haemorrhage, Anorectal Discomfort (8268847-1)
Patient was taking Colace. Patient felt the following Colace side effects: rectal haemorrhage, anorectal discomfort on Apr 09, 2012 from UNITED STATES Additional patient health information: Male , 68 years of age, weighting 195.0 lb, . Colace dosage: N/A.

Economic Problem, Polymyalgia Rheumatica, Dizziness, Tricuspid Valve Incompetence, Angina Unstable, Cerebrovascular Accident, Asthenia, Facet Joint Syndrome, Injury (8260839-1)
Adverse event was reported on Mar 19, 2012 by a Female taking Colace (Dosage: N/A) . Location: UNITED STATES , 74 years of age, weighting 226.0 lb, After Colace was administered, patient encountered several Colace side effects: economic problem, polymyalgia rheumatica, dizziness, tricuspid valve incompetence, angina unstable, cerebrovascular accident, asthenia, facet joint syndrome, injury.
Multiple concurrent drugs taken:
  • Spironolactone
  • Xanax
  • Coricidin D Srt
  • Furosemide
  • Potassium
  • Tylenol
  • Alprazolam
  • Chloride
Patient was hospitalized.

Contusion, Musculoskeletal Pain, Pneumonia, Serum Ferritin Increased, Insomnia, Bacteraemia, Device Related Infection (8244535-2)
on Mar 20, 2012 Female from UNITED STATES , weighting 159.8 lb, was treated with Colace. Directly after, patient experienced the unwanted or unexpected Colace side effects: contusion, musculoskeletal pain, pneumonia, serum ferritin increased, insomnia, bacteraemia, device related infection. Colace dosage: Unk.
Associated medications used:
  • Aspirin (Unk)
  • Phenergan Hcl (Unk)
  • Vancomycin Hcl (Unk)
  • Benadryl (Unk)
  • Multi-vitamin (Unk)
  • Soliris (900 Mg, Q2w)
  • Lovenox (100 Mg, Qd)
  • Albuterol (Unk)
Patient was hospitalized.


Arthralgia, Grip Strength Decreased, Contusion, Lip Dry, Gait Disturbance, Bone Pain, Hypoaesthesia, Dyspepsia, Chapped Lips (8224917-5)
on Jul 09, 2009 Male from UNITED STATES , 67 years of age, was treated with Colace (docusate Sodium). Patient felt the following Colace side effects: arthralgia, grip strength decreased, contusion, lip dry, gait disturbance, bone pain, hypoaesthesia, dyspepsia, chapped lips. Colace (docusate Sodium) dosage: N/A.
Multiple prescriptions taken:
  • Soma
  • Zocor
  • Afinitor (10 Mg, Qd, Oral)
  • Aspirin
  • Gabapentin
  • Lortab
  • Lisinopril
  • Lantus


Convulsion (8211472-9)
Patient was taking Colace. After Colace was administered, patient encountered several Colace side effects: convulsion on Mar 03, 2012 from UNITED STATES Additional patient health information: Female , weighting 143.1 lb, was diagnosed with
  • constipation
and. Colace dosage: Unk.
Multiple concurrent drugs taken:
  • Dulcolax (Unk)
  • Furosemide (Unk)
  • Keppra (Unk)
  • Klor-con (Unk)
  • Lovenox (Unk)
  • Zofran (Unk)
  • Milk Of Magnesia Tab (Unk)
  • Synthroid (Unk)
Patient was hospitalized.

Enterococcal Infection, Diarrhoea, Flatulence, Device Related Infection, Sinus Tachycardia, Abdominal Distension, Vomiting, Orthostatic Hypotension, Pruritus (8203674-2)
Adverse event was reported on Feb 22, 2012 by a Female taking Colace (docusate Sodium) (Dosage: N/A) . Location: UNITED STATES , 33 years of age, weighting 159.4 lb, Directly after, patient experienced the unwanted or unexpected Colace side effects: enterococcal infection, diarrhoea, flatulence, device related infection, sinus tachycardia, abdominal distension, vomiting, orthostatic hypotension, pruritus.
Associated medications used:
  • Adcetris (1.8 Mg/kg, Unk, Intravenous)
  • Enoxaparin Sodium
  • Colace (docuaste Sodium)
  • Tenofovir
  • Everolimus (everolimus)
  • Amoxicillin Trihydrate
  • Entecavir (entecavir)
  • Multivitamin (vitamin Nos)
Patient was hospitalized.

Convulsion (8175196-9)
on Feb 28, 2012 Female from UNITED STATES , weighting 143.1 lb, was diagnosed with
  • constipation
  • nausea
and was treated with Colace. Patient felt the following Colace side effects: convulsion. Colace dosage: Unk.
Multiple prescriptions taken:
  • Prochlorperazine (Unk)
  • Milk Of Magnesia Tab (Unk)
  • Synthroid (Unk)
  • Furosemide (Unk)
  • Lovenox (Unk)
  • Klor-con (Unk)
  • Keppra (Unk)
  • Crizotinib (250 Mg, 2x/day)
Patient was hospitalized.

(8171778-9)
on Feb 23, 2012 Male from UNITED STATES , 39 years of age, was treated with Colace. . Colace dosage: N/A.
Multiple concurrent drugs taken:
  • Bactrim
  • Vitamin D
  • Tarceva
  • Decadron
  • Votrient (400mg Per Day)
  • Afinitor
  • Dasatinib
  • Doxycycline


Antinuclear Antibody Positive, Systemic Lupus Erythematosus (8163076-4)
Patient was taking Colace. Directly after, patient experienced the unwanted or unexpected Colace side effects: antinuclear antibody positive, systemic lupus erythematosus on Feb 21, 2012 from UNITED STATES Additional patient health information: Female , 40 years of age, . Colace dosage: N/A.
Associated medications used:
  • Ambien Cr
  • Lamictal (200mg At Night)
  • Nortriptyline Hcl
  • Zoloft
  • Klonopin


Dehydration, Injection Site Pain, Asthenia, Somnolence, Urinary Tract Infection, Musculoskeletal Stiffness, Feeling Abnormal (8161366-2)
Adverse event was reported on Feb 16, 2012 by a Female taking Colace (Dosage: N/A) . Location: UNITED STATES , weighting 145.1 lb, Patient felt the following Colace side effects: dehydration, injection site pain, asthenia, somnolence, urinary tract infection, musculoskeletal stiffness, feeling abnormal.
Multiple prescriptions taken:
  • Citracal + D
  • Oxybutynin
  • Prednisone
  • Aspirin
  • Vitamin D
  • Humira
  • Nexium
  • Magnesium
Patient was hospitalized.

Small Intestinal Obstruction, Chest Pain, Nausea, Pulmonary Embolism, Deep Vein Thrombosis, Obstruction Gastric (8152263-7)
on Feb 13, 2012 Female from UNITED STATES , 19 years of age, was diagnosed with
  • abdominal pain upper
  • oral contraception
and was treated with Colace. After Colace was administered, patient encountered several Colace side effects: small intestinal obstruction, chest pain, nausea, pulmonary embolism, deep vein thrombosis, obstruction gastric. Colace dosage: Unk.
Multiple concurrent drugs taken:
  • Yaz (Unk)
  • Ortho Tri-cyclen (Unk)
  • Yaz
Patient was hospitalized.

Cough, Pericardial Rub, Incision Site Pain, Sneezing, Coronary Artery Disease, Incision Site Complication, Prostatomegaly, Hyperlipidaemia, Essential Hypertension (8147595-2)
on Feb 14, 2012 Male from UNITED STATES , 62 years of age, weighting 237.0 lb, was treated with Colace. Directly after, patient experienced the unwanted or unexpected Colace side effects: cough, pericardial rub, incision site pain, sneezing, coronary artery disease, incision site complication, prostatomegaly, hyperlipidaemia, essential hypertension. Colace dosage: N/A.
Associated medications used:
  • Norco (5-325 Mg As Required)
  • Lisinopril
  • Crestor
  • Metoprolol Succinate
  • Aspirin
  • Uroxatral


Pulmonary Congestion, Rhinorrhoea, Vertigo, Condition Aggravated, Blood Pressure Increased, Cerebral Haemorrhage, Nausea, Dizziness, Dermatitis (8144173-6)
Patient was taking Colace. Patient felt the following Colace side effects: pulmonary congestion, rhinorrhoea, vertigo, condition aggravated, blood pressure increased, cerebral haemorrhage, nausea, dizziness, dermatitis on Feb 08, 2012 from UNITED STATES Additional patient health information: Male , 64 years of age, weighting 218.0 lb, . Colace dosage: N/A.
Multiple prescriptions taken:
  • Amiodarone Hcl
  • Prilosec
  • Clonidine
  • Clopidogrel Bisulfate (Unit Dose: 75 Mg)
  • Clopidogrel Bisulfate (Unit Dose: 75 Mg)
  • Aspirin
  • Prevacid
  • Lortab
Patient was hospitalized.

Diarrhoea, Blood Potassium Abnormal, Product Substitution Issue (8143790-7)
Adverse event was reported on Jan 30, 2012 by a Female taking Colace (Dosage: N/A) . Location: UNITED STATES , 86 years of age, weighting 123.0 lb, After Colace was administered, patient encountered several Colace side effects: diarrhoea, blood potassium abnormal, product substitution issue.
Multiple concurrent drugs taken:
  • Multi-vitamins
  • Atelvia
  • Cozaar
  • Pravastatin
  • Vitamin B6
  • Omeprazole
  • Tramadol Hcl
  • Metolazone
Patient was hospitalized.

Cardiac Failure Congestive, Clostridium Difficile Colitis, Lung Infiltration, Hypothyroidism, Septic Shock, Encephalopathy, Azotaemia, Chills, Pyrexia (8123631-4)
on Feb 02, 2012 Male from UNITED STATES , weighting 156.1 lb, was treated with Colace. Directly after, patient experienced the unwanted or unexpected Colace side effects: cardiac failure congestive, clostridium difficile colitis, lung infiltration, hypothyroidism, septic shock, encephalopathy, azotaemia, chills, pyrexia. Colace dosage: 250 Mg, At Bed Time.
Associated medications used:
  • Synthroid (75 Ug, Daily)
  • Ondansetron Hcl
  • Amlodipine (10 Mg, Unk)
  • Simvastatin
  • Guaifenesin (600 Mg,every 12 H)
  • Sorbitol 50pc Inj
  • Clonidine (0.1 Mg, Bid)
  • Epogen (10, 000 Units Evey 48 Hours)
Patient was hospitalized.

Foetal Exposure During Pregnancy, Tricuspid Valve Incompetence, Right Ventricular Hypertrophy, Hypoglycaemia, Dilatation Atrial, Pulmonary Artery Stenosis, Pericardial Effusion, Cardiomegaly, Respiratory Failure (8123121-9)
on Feb 03, 2012 Male from UNITED STATES , weighting 9.91 lb, was diagnosed with
  • constipation
and was treated with Colace. Patient felt the following Colace side effects: foetal exposure during pregnancy, tricuspid valve incompetence, right ventricular hypertrophy, hypoglycaemia, dilatation atrial, pulmonary artery stenosis, pericardial effusion, cardiomegaly, respiratory failure. Colace dosage: 100 Mg, 2x/day.
Multiple prescriptions taken:
  • Magnesium (10 Ml, Every 6 Hours When Needed)
  • Ambien (5 Mg, When Needed At Bedtime)
  • Polyethylene Glycol (17 G, Every Day For One Week)
  • Effexor Xr (150 Mg)
  • Effexor Xr (150 Mg, 1x/day)
  • Multi-vitamins (One Tablet, Once Daily)
  • Ketorolac Tromethamine (Unk,)
  • Acetaminophen (650 Mg, Every Four Hours When Needed)
Patient was hospitalized.

Rash (8086525-9)
Patient was taking Colace. After Colace was administered, patient encountered several Colace side effects: rash on Apr 06, 2011 from UNITED STATES Additional patient health information: Male , 74 years of age, was diagnosed with
  • constipation prophylaxis
and. Colace dosage: N/A.
Multiple concurrent drugs taken:
  • Aspirin
  • Prednisone Tab
  • Humira
  • Istatol Eye Drops (One Drop In Each Eye Daily)
  • Azilect
  • Acidophilus
  • Fosamax
  • Mirapex (0.75/0.375 Mg)


Dysstasia, Memory Impairment, Coma, Gastrooesophageal Reflux Disease (8064573-2)
Adverse event was reported on Jan 17, 2012 by a Male taking Colace (Dosage: N/A) . Location: UNITED STATES , 54 years of age, weighting 229.9 lb, Directly after, patient experienced the unwanted or unexpected Colace side effects: dysstasia, memory impairment, coma, gastrooesophageal reflux disease.
Associated medications used:
  • Celexa
  • Tramadol Hcl
Patient was hospitalized.

Gastrooesophageal Reflux Disease (8061529-0)
on Jan 11, 2012 Male from UNITED STATES , 54 years of age, weighting 229.9 lb, was treated with Colace. Patient felt the following Colace side effects: gastrooesophageal reflux disease. Colace dosage: N/A.
Multiple prescriptions taken:
  • Nexium
  • Flumax


Weight Increased, Swelling, Micturition Frequency Decreased (8056695-7)
on May 17, 2011 Male from UNITED STATES , 67 years of age, weighting 185.2 lb, was treated with Colace. After Colace was administered, patient encountered several Colace side effects: weight increased, swelling, micturition frequency decreased. Colace dosage: N/A.

Renal Failure, Renal Injury, Fear, Pain, Renal Impairment, Anhedonia, Amputation, Unevaluable Event (8042014-9)
Patient was taking Colace. Directly after, patient experienced the unwanted or unexpected Colace side effects: renal failure, renal injury, fear, pain, renal impairment, anhedonia, amputation, unevaluable event on Jan 05, 2012 from UNITED STATES Additional patient health information: Female , 71 years of age, weighting 160.0 lb, . Colace dosage: N/A.
Associated medications used:
  • Metoprolol Succinate
  • Lasix
  • Scopolamine
  • Persantine (75mg)
  • Integrilin (Unk)
  • Phenergan (6.25mg)
  • Dopamine Hcl
  • Trasylol (Test Dose: 1ml Then 200ml Pump Prime)


Refusal Of Treatment By Patient, Chest Pain, Hypotension (8037914-X)
Adverse event was reported on Dec 22, 2011 by a Male taking Colace (docusate Sodium) (Dosage: N/A) . Location: UNITED STATES , 65 years of age, weighting 220.5 lb, Patient felt the following Colace side effects: refusal of treatment by patient, chest pain, hypotension.
Multiple prescriptions taken:
  • Keppra
  • Omeprazole
  • Triamcinolone
  • Decadron
  • Nystatin
  • Seroquel
  • Dalteparin Sodium (18000; 15000; 18000, Subcutaneous)
  • Dalteparin Sodium (18000; 15000; 18000, Subcutaneous)
Patient was hospitalized.

Adenoidal Disorder, Musculoskeletal Discomfort, Psychomotor Hyperactivity, Blood Magnesium Decreased, Umbilical Hernia, Bursitis, Rotator Cuff Syndrome, Finger Deformity (8016248-3)
on Dec 22, 2011 Female from UNITED STATES , 65 years of age, weighting 145.5 lb, was treated with Colace. After Colace was administered, patient encountered several Colace side effects: adenoidal disorder, musculoskeletal discomfort, psychomotor hyperactivity, blood magnesium decreased, umbilical hernia, bursitis, rotator cuff syndrome, finger deformity. Colace dosage: Bid.
Multiple concurrent drugs taken:
  • Cholecalciferol
  • Citracal + D
  • Fosamax
  • Synthroid
Patient was hospitalized and became disabled.

Syncope, Haemoglobin Decreased, Bradycardia, Haematocrit Decreased (8004520-2)
on Dec 21, 2011 Male from UNITED STATES , 79 years of age, weighting 185.2 lb, was treated with Colace. Directly after, patient experienced the unwanted or unexpected Colace side effects: syncope, haemoglobin decreased, bradycardia, haematocrit decreased. Colace dosage: N/A.
Associated medications used:
  • Thalidomide (150mg Eod Po Recent X3 Mos)
  • M.v.i.
  • Singulair
  • Thalidomide (100 Mg Eod Po)
Patient was hospitalized.

Showing 1-25 of 172 

Colace Health Episodes

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Colace Information

Alternative COLACE Names:DOCUSATE

Active Ingredient: DOCUSATE

More About Colace

Side Effects reported to FDA: 172. View Colace Adverse Reports

Colace safety alerts: No

Reported deaths: 16

Reported hospitalizations: 79

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