PatientsVille.com Logo

PatientsVille

Cotareg Side Effects

Common Cotareg Side Effects


The most commonly reported Cotareg side effects (click to view or check a box to report):

Hyponatraemia (22)
Renal Failure Acute (14)
Malaise (14)
Blood Creatinine Increased (11)
Diarrhoea (11)
Fall (11)
Hypokalaemia (11)
Dizziness (10)
Dehydration (10)
Fatigue (9)
Confusional State (9)
Hypotension (8)
Erythema (8)
Vomiting (7)
Pruritus (7)
Bradycardia (6)
Creatinine Renal Clearance Decreased (6)
Renal Failure (6)
Nausea (6)
Dyspnoea (6)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

Cotareg Side Effects Reported to FDA

The following Cotareg reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.


The appearance of Cotareg on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.
Atrial Fibrillation
This is a report of a 78-year-old female patient (weight: NA) from US, suffering from the following symptoms/conditions: NA, who was treated with Cotareg (dosage: Unk Ukn, Unk, start time: Nov 28, 2013), combined with:
  • Sintrom (1 Mg, Unk)
  • Sintrom (25 Mg, Unk)
  • Trastuzumab (600 Mg, Once In 3 Week)
  • Trastuzumab (600 Mg , Once In 3 Wk)
  • Trastuzumab (600 Mg, Once In 3 Week)
  • Trastuzumab (600 Mg , 1 In 3 Wkunk)
  • Lanoxin (Unk Ukn, Unk)
  • Durogesic (Unk Ukn, Unk)
and developed a serious reaction and side effect(s). The consumer presented with:
  • Atrial Fibrillation
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Cotareg treatment in female patients, resulting in atrial fibrillation side effect. The patient was hospitalized.

Renal Failure Acute, Diarrhoea, Nausea, Renal Tubular Disorder
This report suggests a potential Cotareg Renal Failure Acute, Diarrhoea, Nausea, Renal Tubular Disorder side effect(s) that can have serious consequences. A 60-year-old female patient (weight: NA) from FR was diagnosed with the following symptoms/conditions: NA and used Cotareg (dosage: Once Daily (qd)) starting Sep 24, 2013. Soon after starting Cotareg the patient began experiencing various side effects, including:
  • Renal Failure Acute
  • Diarrhoea
  • Nausea
  • Renal Tubular Disorder
Drugs used concurrently:
  • Cisplatin (134.25 Mg, Unk)
  • Contramal (200 Mg, Qd)
  • Imovane (Once Daily)
  • Xanax
  • Iressa (250 Mg, Qd)
  • Doxycycline (100 Mg, Qd)
  • Bevacizumab (585 Mg, Unk)
  • Pemetrexed (895 Mg, Unk)
The patient was hospitalized. Although Cotareg demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as renal failure acute, may still occur.

Tubulointerstitial Nephritis, Renal Failure Acute
This Tubulointerstitial Nephritis, Renal Failure Acute problem was reported by a health professional from FR. A 66-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: hypertension,lung adenocarcinoma. On Oct 08, 2013 this consumer started treatment with Cotareg (dosage: Unk Ukn, Unk). The following drugs were being taken at the same time:
  • Alimta (Unk Ukn, Unk)
  • Cisplatine (Unk Ukn, Unk)
When commencing Cotareg, the patient experienced the following unwanted symptoms/side effects:
  • Tubulointerstitial Nephritis
  • Renal Failure Acute
The patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as tubulointerstitial nephritis, may become evident only after a product is in use by the general population.

Hypotension, Renal Failure Acute
This is a report of a 70-year-old female patient (weight: NA) from COUNTRY NOT SPECIFIED. The patient developed the following symptoms/conditions: hypertension,arthralgia and was treated with Cotareg (dosage: 1 Df, (160 Mg Vala/ Unk) Qd) starting Oct 11, 2012. Concurrently used drugs:
  • Ibuprofen Sandoz (Unk Ukn, Unk)
  • Zanidip (1 Df, (10 Mg) Qd)
  • Zoloft (sertraline Hydrochloride) (50 Mg, Qd)
  • Xanax (0.25 Mg, Qd)
  • Imovane (1 Df, Qd)
  • Levothyrox (50 Ug, Qd)
  • Crestor (5 Mg, Qd)
  • Inexium//esomeprazole Magnesium (20 Mg, Qd)
Soon after that, the consumer experienced the following side effects:
  • Hypotension
  • Renal Failure Acute
The patient was hospitalized. This opens a possibility that Cotareg treatment could cause the above reactions, including hypotension, and some female subjects may be more susceptible.


Cerebral Hypoperfusion, Confusional State, Hyponatraemia, Hypotension
A 76-year-old male patient (weight: NA) from IT with the following symptoms/conditions: hypertension,constipation started Cotareg treatment (dosage: 1 Df (1 Posologic Unit) A Day) on Oct 06, 2013. Soon after starting Cotareg treatment, the subject experienced various side effects, including:
  • Cerebral Hypoperfusion
  • Confusional State
  • Hyponatraemia
  • Hypotension
Concurrently used drugs:
  • Laevolac (Unk Ukn, Unk)
The patient was hospitalized. This finding indicates that some male patients could be more vulnerable to Cotareg.

Contusion, Femur Fracture, Syncope
A 57-year-old male patient from IT (weight: NA) experienced symptoms, such as: hypertension and was treated with Cotareg(dosage: 1 Df (1 Posologic Unit) Qd). The treatment was initiated on Mar 20, 2013. After that a consumer reported the following side effect(s):
  • Contusion
  • Femur Fracture
  • Syncope
Concurrently used drugs, which potentially could have contributed to side effect(s) or affected Cotareg efficacy: NA.The patient was hospitalized.

Hypoglycaemic Coma, Diarrhoea, Renal Failure Acute
In this report, Cotareg was administered for the following condition: hypertension,type 2 diabetes mellitus,sciatica.A 79-year-old female consumer from FR (weight: NA) started Cotareg treatment (dosage: 1 Df (160mg Vals, 12.5mg Hctz), Qd) on Jul 30, 2013.Sometime after starting the treatment, the patient complained of the following side effect(s):
  • Hypoglycaemic Coma
  • Diarrhoea
  • Renal Failure Acute
A possible interaction with other drugs could have contributed to this reaction:
  • Amarel (1 Mg, Bid)
  • Profenid (100 Mg, Qd)
  • Miorel (4 Mg, Bid)
  • Klipal Codeine (1 Df (600mg Para/ 50mg Code), Qid)
  • Lipanthyl (145 Mg, Qd)
  • Loxen (20 Mg, Qd)
  • Daflon (diosmin/hesperidin) (500 Mg, Bid)
  • Topalgic (50 Mg, Bid)
Establishing a causal relationship between a specific drug and consumer's side effects is complex, but it is possible that in this report Cotareg treatment could be related to the listed above side effect(s).

Blood Pressure Systolic Increased, Weight Decreased, Blood Pressure Decreased, Abdominal Pain, Dizziness
This is a report of the following Cotareg side effect(s):
  • Blood Pressure Systolic Increased
  • Weight Decreased
  • Blood Pressure Decreased
  • Abdominal Pain
  • Dizziness
A 73-year-old female patient from FR (weight: NA) presented with the following condition: hypertension and received a treatment with Cotareg (dosage: 1 Df (80 Mg Vals,12.5 Mg Hct), Every 2 Days) starting: Sep 22, 2013.The following concurrently used drugs could have generated interactions: NA.This report suggests that a Cotareg treatment could be associated with the listed above side effect(s).

Confusional State, Hyponatraemia
This Cotareg report was submitted by a 88-year-old female consumer from IT (weight: NA). The patient was diagnosed with: hypertension and Cotareg was administered (dosage: 1 Df, Daily) starting: Jan 01, 2011. The consumer developed a set of symptoms:
  • Confusional State
  • Hyponatraemia
Other drugs used simultaneously:
  • Lasix (1 Df (25mg), Daily)
  • Plaquenil (Unk Ukn, Unk)
  • Deltacortene (Unk Ukn, Unk)
  • Cardirene (Unk Ukn, Unk)
  • Nexum (Unk Ukn, Unk)
The patient was hospitalized.Those unexpected symptoms could be linked to a Cotareg treatment, however establishing a potential drug-safety problem requires a more detailed clinical analysis.

Cholestasis, Hepatocellular Injury, Hepatotoxicity, Renal Failure Acute, Nephropathy Toxic, Haemolysis
This is a report of a possible correlation between Cotareg use and the following symptoms/side effect(s):
  • Cholestasis
  • Hepatocellular Injury
  • Hepatotoxicity
  • Renal Failure Acute
  • Nephropathy Toxic
  • Haemolysis
which could contribute to an assessment of Cotareg risk profile.A 84-year-old female consumer from FR (weight: NA) was suffering from hypertension and was treated with Cotareg (dosage: 1 Df, Daily (160 Mg Vals, Unk Hctz)) starting NS.Other concurrent medications:
  • Xanax (1 Df, Tid)
  • Norset (15 Mg, Daily)
  • Mono-tildiem (1 Df, Daily)
  • Tahor (1 Df (40 Mg) Daily)
  • Lasilix (1 Df, Daily)
  • Hyperium (1 Df, Daily)
The patient was hospitalized.

Hyponatraemia
A 90-year-old female patient from FR (weight: NA) presented with the following symptoms: hypertension,condition aggravated,cranial nerve disorder,gastric disorder,hypercholesterolaemia,hypothyroidism and after a treatment with Cotareg (dosage: 1 Df (160/12.5 Mg), Qd) experienced the following side effect(s):
  • Hyponatraemia
The treatment was started on Jul 19, 2013. Cotareg was used in combination with the following drugs:
  • Voltarene Lp (75 Mg, Qd)
  • Voltarene Lp
  • Mopral (Unk Ukn, Unk)
  • Pravastatin Aaa (20 Mg, Qd)
  • Levothyrox (75 Ug, Qd)
  • Loxen (50 Mg, Qd)
  • Veratran (5 Mg, Qd)
  • Lamaline (2 Df, Tid)
The patient was hospitalized.This report could alert potential Cotareg consumers.

Pustular Psoriasis
In this report, a 63-year-old female patient from FR (weight: NA) was affected by a possible Cotareg side effect.The patient was diagnosed with hypertension,prophylaxis. After a treatment with Cotareg (dosage: Unk Ukn, Unk, start date: 201207), the patient experienced the following side effect(s):
  • Pustular Psoriasis
The following simultaneously used drugs could have led to this reaction:
  • Optiject (350 Mg D?iodine/ml)
The patient was hospitalized.The findings here stress that side effects should be taken into consideration when evaluating a Cotareg treatment.

Colitis Microscopic, Diarrhoea
This is a report of a 67-year-old female patient from FR (weight: NA), who used Cotareg (dosage: Unk Ukn, Unk) for a treatment of NA. After starting a treatment on 2005, the patient experienced the following side effect(s):
  • Colitis Microscopic
  • Diarrhoea
The following drugs could possibly have interacted with the Cotareg treatment
  • Hyperium (1 Mg, Unk)
  • Metformin (Unk Ukn, Unk)
  • Seloken (Unk Ukn, Unk)
Taken together, these observations suggest that a Cotareg treatment could be related to side effect(s), such as Colitis Microscopic, Diarrhoea.

Blood Pressure Inadequately Controlled, Vascular Occlusion, Ear Pain, Sleep Disorder
This blood pressure inadequately controlled side effect was reported by a consumer or non-health professional from ZA. A 77-year-old male patient (weight:NA) experienced the following symptoms/conditions: hypertension. The patient was prescribed Cotareg (dosage: 80 Mg, Daily), which was started on 201209. Concurrently used drugs: NA. When starting to take Cotareg the consumer reported the following symptoms:
  • Blood Pressure Inadequately Controlled
  • Vascular Occlusion
  • Ear Pain
  • Sleep Disorder
The patient was hospitalized. These side effects may potentially be related to Cotareg.

Face Oedema, Eczema, Toxic Skin Eruption
This is a Cotareg side effect report of a 75-year-old male patient (weight:NA) from FR, suffering from the following symptoms/conditions: NA, who was treated with Cotareg (dosage:NA, start time: NS), combined with:
  • Procoralan
  • Pravadual
  • Olmetec
  • Duoplavin (Unk)
, and developed a serious reaction and a face oedema side effect. The patient presented with:
  • Face Oedema
  • Eczema
  • Toxic Skin Eruption
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Cotareg treatment in male patients suffering from NA, resulting in face oedema.

Mucosal Inflammation, Neutropenia
This report suggests a potential Cotareg mucosal inflammation side effect(s) that can have serious consequences. A 65-year-old female patient from FR (weight:NA) was diagnosed with the following health condition(s): NA and used Cotareg (dosage: 1 Df (vals 160mg, Hctz 25mg), Qd) starting Mar 28, 2011. Soon after starting Cotareg the patient began experiencing various side effects, including:
  • Mucosal Inflammation
  • Neutropenia
Drugs used concurrently:
  • Taxotere (Unk Ukn, Unk)
  • Herceptin (Unk Ukn, Unk)
  • Efferalgan (If Needed)
  • Lopressor (200 Mg, Qd)
  • Tahor (10 Mg, Qd)
  • Rilmenidine (1 Mg, Qd)
  • Stablon (12.5 Mg, Tid)
  • Seresta (0.5 Df (50 Mg) Qd)
The patient was hospitalized. Although Cotareg demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as mucosal inflammation, may still occur.

Lichenoid Keratosis, Pigmentation Disorder, Acanthosis, Lymphocytic Infiltration, Ichthyosis, Toxic Skin Eruption
This lichenoid keratosis problem was reported by a consumer or non-health professional from FR. A 65-year-old male patient (weight: NA) was diagnosed with the following medical condition(s): hypertension.On 2012 a consumer started treatment with Cotareg (dosage: 1 Df (160 Mg Vals And 12.5 Mg Hctz), Qd). The following drugs/medications were being taken at the same time:
  • Zofenopril (1 Df, Qd)
When commencing Cotareg, the patient experienced the following unwanted symptoms /side effects:
  • Lichenoid Keratosis
  • Pigmentation Disorder
  • Acanthosis
  • Lymphocytic Infiltration
  • Ichthyosis
  • Toxic Skin Eruption
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as lichenoid keratosis, may become evident only after a product is in use by the general population.

Weight Decreased, Hyperkalaemia, Renal Failure Acute, Vomiting, Diarrhoea, Body Temperature Decreased, Heart Rate Increased, Metabolic Acidosis, Blood Potassium Decreased
This is a Cotareg side effect report of a 63-year-old female patient (weight: NA) from FR. The patient developed the following symptoms/conditions: hypertension,gout and was treated with Cotareg (dosage: 1 Df (vals 80 Mg, Hctz 12.5 Mg) Qd) starting Mar 25, 2013. Concurrently used drugs:
  • Colchicine Opocalium (1 Mg, Unk)
  • Nifluril (1 Df (250 Mg) Tid)
  • Metformine (3 G, Daily)
Soon after that, the consumer experienced the following of symptoms:
  • Weight Decreased
  • Hyperkalaemia
  • Renal Failure Acute
  • Vomiting
  • Diarrhoea
  • Body Temperature Decreased
  • Heart Rate Increased
  • Metabolic Acidosis
  • Blood Potassium Decreased
The patient was hospitalized. This opens a possibility that Cotareg could cause weight decreased and that some female patients may be more susceptible.

Rash Maculo-papular, Pruritus
A 77-year-old female patient (weight: NA) from FR with the following symptoms: NA started Cotareg treatment (dosage: 1 Df (160 Mg Vals And 12.5 Mg Hydro), Qd) on Jan 21, 2013. Soon after starting Cotareg treatment, the consumer experienced several side effects, including:
  • Rash Maculo-papular
  • Pruritus
. Concurrently used drugs:
  • Clarithromycin (250 Mg, Qd)
  • Fucidine (500 Mg, Tid)
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Cotareg side effects, such as rash maculo-papular.

Pyrexia, Myalgia, Alanine Aminotransferase Increased, Blood Alkaline Phosphatase Increased
This pyrexia side effect was reported by a health professional from FR. A 65-year-old male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Cotareg (dosage: NA), which was started on NS. Concurrently used drugs:
  • Metformin
  • Victoza
  • Levemir
.When starting to take Cotareg the consumer reported symptoms, such as:
  • Pyrexia
  • Myalgia
  • Alanine Aminotransferase Increased
  • Blood Alkaline Phosphatase Increased
These side effects may potentially be related to Cotareg. The patient was hospitalized.

Renal Failure Acute, Anuria, Hyperkalaemia
This is a report of a 88-year-old female patient (weight: NA) from FR, suffering from the following symptoms/conditions: NA, who was treated with Cotareg (dosage: 1 Df (160 Mg Val/12.5 Mg Hct) Daily, start time: NS), combined with:
  • Furosemide (20 Mg, Daily)
  • Diltiazem (1 Df, Daily)
  • Eupressyl (1 Df, Bid)
  • Pravastatin Sodium (20 Mg, Unk)
  • Previscan (10 Mg, Daily)
  • Nitriderm (1 Df Daily)
  • Pantoprazole (20 Mg, Daily)
  • Paracetamol (1.5 G, Daily)
and developed a serious reaction and side effect(s). The consumer presented with:
  • Renal Failure Acute
  • Anuria
  • Hyperkalaemia
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Cotareg treatment in female patients, resulting in renal failure acute side effect. The patient was hospitalized.

Burning Sensation, Oedema Peripheral, Pruritus, Pain In Extremity, Gait Disturbance, Neuropathy Peripheral
This report suggests a potential Cotareg Burning Sensation, Oedema Peripheral, Pruritus, Pain In Extremity, Gait Disturbance, Neuropathy Peripheral side effect(s) that can have serious consequences. A 67-year-old male patient (weight: NA) from FR was diagnosed with the following symptoms/conditions: hypertension and used Cotareg (dosage: 1 Df, (160 Mg Vals And 12.5 Mg Hctz),qd) starting 201209. Soon after starting Cotareg the patient began experiencing various side effects, including:
  • Burning Sensation
  • Oedema Peripheral
  • Pruritus
  • Pain In Extremity
  • Gait Disturbance
  • Neuropathy Peripheral
Drugs used concurrently: NA. Although Cotareg demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as burning sensation, may still occur.

Arrhythmia, Hyponatraemia
This Arrhythmia, Hyponatraemia problem was reported by a health professional from IT. A 92-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: hypertension. On Jan 01, 2012 this consumer started treatment with Cotareg (dosage: 0.5 Df, Daily (320 Mg Vals, 12.5 Mg Hydr)). The following drugs were being taken at the same time:
  • Lasix (25 Mg, Daily)
  • Tamsulosin
  • Avodart (0.5 Mg, Unk)
  • Lanoxin (0.125 Mg, Unk)
  • Cardirene (160 Mg, Unk)
When commencing Cotareg, the patient experienced the following unwanted symptoms/side effects:
  • Arrhythmia
  • Hyponatraemia
The patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as arrhythmia, may become evident only after a product is in use by the general population.

Bradycardia, Lactic Acidosis, Cardiogenic Shock
This is a report of a 56-year-old female patient (weight: NA) from FR. The patient developed the following symptoms/conditions: NA and was treated with Cotareg (dosage: 30 Df, Unk) starting May 18, 2012. Concurrently used drugs:
  • Isoptine (45 Df, Unk)
  • Tahor (30 Df, Unk)
Soon after that, the consumer experienced the following side effects:
  • Bradycardia
  • Lactic Acidosis
  • Cardiogenic Shock
This opens a possibility that Cotareg treatment could cause the above reactions, including bradycardia, and some female subjects may be more susceptible.

Torsade De Pointes, Cardiac Arrest, Electrocardiogram Qt Prolonged, Coma, Hypokalaemia, Bradycardia, Decerebration, Hypokinesia, Troponin Increased
A 45-year-old female patient (weight: NA) from FR with the following symptoms/conditions: NA started Cotareg treatment (dosage: 1 Df (80 Mg Vals /12.5 Mg Hctz), Unk) on Oct 12, 2012. Soon after starting Cotareg treatment, the subject experienced various side effects, including:
  • Torsade De Pointes
  • Cardiac Arrest
  • Electrocardiogram Qt Prolonged
  • Coma
  • Hypokalaemia
  • Bradycardia
  • Decerebration
  • Hypokinesia
  • Troponin Increased
Concurrently used drugs:
  • Haldol (5 Mg, Unk)
  • Dipiperon (40 Mg, Unk)
  • Cerazet
  • Prozac
  • Xanax
This finding indicates that some female patients could be more vulnerable to Cotareg.

1 of 6 



Top 10 Cotareg Side Effects for Women

Women Side EffectsReports
Hyponatraemia 20
Dizziness 10
Hypokalaemia 10
Malaise 10
Renal Failure Acute 10
Blood Creatinine Increased 9
Diarrhoea 9
Fall 9
Confusional State 8
Dehydration 7

Top 10 Cotareg Side Effects for Men

Men Side EffectsReports
Erythema 4
Fatigue 4
Headache 4
Hypotension 4
Malaise 4
Renal Failure 4
Renal Failure Acute 4
Dehydration 3
Dyspnoea 3
Face Oedema 3

Keep Track of Side Effects

Note Your Observations

It is really important to keep of your symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


    Discuss Cotareg Side Effects

    Did You Have a Cotareg Side Effect?

    Yes, Severe
    Yes, Moderate
    Yes, Minor
    No

    How Effective is Cotareg for You?

    Exceeded Expectations
    Effective
    Somewhat Effective
    Not Effective