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Cyclophospham Side Effects

Common Cyclophospham Side Effects

The most commonly reported Cyclophospham side effects (click to view or check a box to report):

Febrile Neutropenia (430)
Neutropenia (388)
Pyrexia (363)
Nausea (229)
White Blood Cell Count Decreased (196)
Vomiting (187)
Diarrhoea (186)
Pneumonia (186)
Hypotension (182)
Dyspnoea (181)
Anaemia (164)
Fatigue (161)
Neutrophil Count Decreased (156)
Sepsis (148)
Dehydration (143)
Abdominal Pain (139)
Haemoglobin Decreased (132)
Thrombocytopenia (131)
Asthenia (126)
Pancytopenia (121)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

Cyclophospham Side Effects Reported to FDA

The following Cyclophospham reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.


The appearance of Cyclophospham on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.
Loss Of Consciousness, Tonic Clonic Movements, Convulsion, Syncope
on Mar 07, 2014 Female from COUNTRY NOT SPECIFIED , 35 years of age, weighting 168.2 lb, was treated with Cyclophosphamide. Directly after, patient experienced the unwanted or unexpected Cyclophospham side effects: loss of consciousness, tonic clonic movements, convulsion, syncope. Cyclophosphamide dosage: N/A.
Associated medications used:
  • Doxorubicin Hydrochloride
Patient was hospitalized.

Oedema Peripheral, Anaemia
Patient was taking Cyclophosphamide For Injection, Usp. Patient felt the following Cyclophospham side effects: oedema peripheral, anaemia on Mar 26, 2014 from US Additional patient health information: Female , 85 years of age, weighting 174.4 lb, was diagnosed with and. Cyclophosphamide For Injection, Usp dosage: N/A.
Multiple prescriptions taken:
  • Velcade
  • Dexamethasone
Patient was hospitalized.

Cardiac Failure Congestive, Exposure During Pregnancy
Adverse event was reported on Mar 07, 2014 by a Female taking Cyclophosphamide (Dosage: N/A) was diagnosed with and. Location: US , 34 years of age, weighting 152.1 lb, After Cyclophospham was administered, patient encountered several Cyclophospham side effects: cardiac failure congestive, exposure during pregnancy.
Multiple concurrent drugs taken:
  • Metoclopramide
  • Promethazine
  • Acetaminophen
  • Doxorubicin
  • Dolasetron Mesylate
  • Aprepitant
  • Doxylamine
  • Hydrocodone


Acute Myeloid Leukaemia
on Mar 06, 2014 Female from US , 45 years of age, weighting 205.0 lb, was treated with Cyclophosphamide. Directly after, patient experienced the unwanted or unexpected Cyclophospham side effects: acute myeloid leukaemia. Cyclophosphamide dosage: N/A.
Associated medications used:
  • Fludarabine Phosphate
  • Rituximab (moab C2b8 Anti Cd20, Chimeric)
Patient was hospitalized.


Catheter Site Pain, Catheter Site Discharge, Culture Positive, Staphylococcal Bacteraemia, Apnoea
on Mar 06, 2014 Female from US , 64 years of age, weighting 285.5 lb, was treated with Cyclophosphamide. Patient felt the following Cyclophospham side effects: catheter site pain, catheter site discharge, culture positive, staphylococcal bacteraemia, apnoea. Cyclophosphamide dosage: N/A.
Multiple prescriptions taken:
  • Doxorubicin Hydrochloride
  • Enulapril
  • Gliclazide
  • Indapamide
  • Januvia
  • Metformin
  • Simvastin
Patient was hospitalized.

Hepatitis B
Patient was taking Cyclophosphamide. After Cyclophospham was administered, patient encountered several Cyclophospham side effects: hepatitis b on Mar 06, 2014 from CN Additional patient health information: Male , 43 years of age, was diagnosed with and. Cyclophosphamide dosage: N/A.

Castleman^s Disease
Adverse event was reported on Mar 06, 2014 by a Male taking Cyclophosphamide Injection 1g (Dosage: N/A) was diagnosed with and. Location: GB , 65 years of age, Directly after, patient experienced the unwanted or unexpected Cyclophospham side effects: castleman^s disease.
Associated medications used:
  • Cisplatin
  • Cytarabine
  • Dexamethasone
  • Doxorubicin Hydrochloride
  • Prednisone
  • Rituximab
  • Vincristine


No Therapeutic Response
on Mar 05, 2014 Male from GB , 41 years of age, was diagnosed with and was treated with Cyclophosphamide Injection 1g. Patient felt the following Cyclophospham side effects: no therapeutic response. Cyclophosphamide Injection 1g dosage: N/A.
Multiple prescriptions taken:
  • Dexamethasone


Staphylococcal Bacteraemia, Catheter Site Pain, Catheter Site Discharge, Apnoea, Weaning Failure
on Feb 26, 2014 Female from US , 64 years of age, weighting 285.5 lb, was treated with Cyclophosphamide. After Cyclophospham was administered, patient encountered several Cyclophospham side effects: staphylococcal bacteraemia, catheter site pain, catheter site discharge, apnoea, weaning failure. Cyclophosphamide dosage: N/A.
Multiple concurrent drugs taken:
  • Doxorubicin Hydrochloride
  • Enalapril
  • Gliclazide
  • Indapamide
  • Januvia
  • Metformin
  • Simvastin
Patient was hospitalized.

Progressive Multifocal Leukoencephalopathy, Pneumonia, Neutropenia, Ophthalmic Herpes Simplex, Clostridium Difficile Colitis
Patient was taking Cyclophosphamide Tablets Usp. Directly after, patient experienced the unwanted or unexpected Cyclophospham side effects: progressive multifocal leukoencephalopathy, pneumonia, neutropenia, ophthalmic herpes simplex, clostridium difficile colitis on Feb 21, 2014 from COUNTRY NOT SPECIFIED Additional patient health information: Female , 65 years of age, was diagnosed with and. Cyclophosphamide Tablets Usp dosage: N/A.
Associated medications used:
  • Fludarabine
  • Rituximab
Patient was hospitalized.

Fatigue, Hyperhidrosis, Chills, Febrile Neutropenia, Infection, Pulmonary Oedema, Productive Cough
Adverse event was reported on Feb 20, 2014 by a Male taking Cyclophosphamide (Dosage: N/A) . Location: US , 47 years of age, weighting 250.0 lb, Patient felt the following Cyclophospham side effects: fatigue, hyperhidrosis, chills, febrile neutropenia, infection, pulmonary oedema, productive cough.
Multiple prescriptions taken:
  • Doxorubicin Hydrochloride
  • Etoposide (vp-16)
  • Rituximab
  • Vincristine Sulfate
Patient was hospitalized.

Neutropenic Sepsis, Febrile Neutropenia, Tremor, Malaise
on Mar 10, 2014 Female from GB , 40 years of age, weighting 140.0 lb, was diagnosed with and was treated with Cyclophosphamide. After Cyclophospham was administered, patient encountered several Cyclophospham side effects: neutropenic sepsis, febrile neutropenia, tremor, malaise. Cyclophosphamide dosage: Unk.
Multiple concurrent drugs taken:
  • Epirubicin Hcl (Unk)
  • 5 Fu (Unk)
  • Neulasta (Unk, 3/52)
Patient was hospitalized.

Weaning Failure, Tracheal Injury, Angiopathy, Soft Tissue Necrosis
on Feb 12, 2014 Female from US , 80 years of age, was diagnosed with and was treated with Cyclophosphamide (cyclophosphamide). Directly after, patient experienced the unwanted or unexpected Cyclophospham side effects: weaning failure, tracheal injury, angiopathy, soft tissue necrosis. Cyclophosphamide (cyclophosphamide) dosage: N/A.
Associated medications used:
  • Vincristine
  • Prednisolone
  • Rituximab


Tachycardia, Hypotension, Malaise, Body Temperature Increased
Patient was taking Cyclophosphamide. Patient felt the following Cyclophospham side effects: tachycardia, hypotension, malaise, body temperature increased on Feb 18, 2014 from US Additional patient health information: Male , 14 years of age, weighting 105.2 lb, . Cyclophosphamide dosage: N/A.
Multiple prescriptions taken:
  • Cytarabine
  • Mercaptopurine
  • Peg-l-asparaginase (k-h)
Patient was hospitalized.

Bone Marrow Failure, Pneumococcal Bacteraemia, Atrioventricular Block Second Degree
Adverse event was reported on Feb 14, 2014 by a Male taking Cyclophosphamide For Injection, Usp (Dosage: 1 G/m2, On Day 1) was diagnosed with and. Location: BE , 59 years of age, After Cyclophospham was administered, patient encountered several Cyclophospham side effects: bone marrow failure, pneumococcal bacteraemia, atrioventricular block second degree.

Progressive Multifocal Leukoencephalopathy, Pyrexia, Pneumonia, Neutropenia, Hypoacusis, Balance Disorder, Optic Atrophy, Neurological Symptom, Condition Aggravated
on Feb 12, 2014 Female from IT , 65 years of age, was diagnosed with and was treated with Cyclophosphamide. Directly after, patient experienced the unwanted or unexpected Cyclophospham side effects: progressive multifocal leukoencephalopathy, pyrexia, pneumonia, neutropenia, hypoacusis, balance disorder, optic atrophy, neurological symptom, condition aggravated. Cyclophosphamide dosage: 6 Cycles Received.
Associated medications used:
  • Fludarabine (6 Cycles Received)
  • Rituximab (6 Cycles Received)
Patient was hospitalized.

Dermatitis Exfoliative, Thrombophlebitis Septic, Osteomyelitis, Staphylococcal Infection
on Feb 12, 2014 Male from US , 64 years of age, was diagnosed with and was treated with Cyclophosphamide For Injection, Usp. Patient felt the following Cyclophospham side effects: dermatitis exfoliative, thrombophlebitis septic, osteomyelitis, staphylococcal infection. Cyclophosphamide For Injection, Usp dosage: N/A.
Multiple prescriptions taken:
  • Doxorubicin
  • Vincristine
  • Prednisone
  • Methotrexate
Patient was hospitalized.

Pruritus, Rash
Patient was taking Cyclophosphamide For Injection, Usp. After Cyclophospham was administered, patient encountered several Cyclophospham side effects: pruritus, rash on Feb 11, 2014 from US Additional patient health information: Female , weighting 116.8 lb, was diagnosed with and. Cyclophosphamide For Injection, Usp dosage: N/A.

Splenic Rupture
Adverse event was reported on Feb 06, 2014 by a Female taking Cyclophosphamide For Injection, Usp (Dosage: N/A) was diagnosed with and. Location: US , 33 years of age, Directly after, patient experienced the unwanted or unexpected Cyclophospham side effects: splenic rupture.
Associated medications used:
  • Cytarabine
  • Daunorubicin
Patient was hospitalized.

Atrioventricular Block Complete
on Feb 06, 2014 Female from US , 35 years of age, was diagnosed with and was treated with Cyclophosphamide For Injection, Usp. Patient felt the following Cyclophospham side effects: atrioventricular block complete. Cyclophosphamide For Injection, Usp dosage: N/A.

Graft Versus Host Disease
on Feb 05, 2014 Male from US , 22 years of age, was treated with Cyclophosphamide For Injection, Usp. After Cyclophospham was administered, patient encountered several Cyclophospham side effects: graft versus host disease. Cyclophosphamide For Injection, Usp dosage: N/A.
Multiple concurrent drugs taken:
  • Fludarabine
  • Melphalan


Pneumonia, Haemoptysis
Patient was taking Cyclophosphamide. Directly after, patient experienced the unwanted or unexpected Cyclophospham side effects: pneumonia, haemoptysis on Feb 03, 2014 from US Additional patient health information: Male , 23 years of age, weighting 149.9 lb, . Cyclophosphamide dosage: N/A.
Associated medications used:
  • Cytarabine
  • Daunorubicin
  • Mercaptopurine
  • Methotrexate
  • Peg-l-asparaginase (k-h)
  • Thioguanine
  • Vincristine Sulfate
Patient was hospitalized.

Graft Versus Host Disease
Adverse event was reported on Feb 04, 2014 by a Female taking Cyclophosphamide For Injection, Usp (Dosage: N/A) . Location: US , 34 years of age, Patient felt the following Cyclophospham side effects: graft versus host disease.
Multiple prescriptions taken:
  • Fludarabine
  • Melphalan


Graft Versus Host Disease
on Feb 04, 2014 Female from US , 16 years of age, was treated with Cyclophosphamide For Injection, Usp. After Cyclophospham was administered, patient encountered several Cyclophospham side effects: graft versus host disease. Cyclophosphamide For Injection, Usp dosage: N/A.
Multiple concurrent drugs taken:
  • Fludarabine
  • Melphalan


Abdominal Pain Upper, Beta Haemolytic Streptococcal Infection, Back Pain
on Jan 30, 2014 Male from US , 59 years of age, was treated with Cyclophosphamide. Directly after, patient experienced the unwanted or unexpected Cyclophospham side effects: abdominal pain upper, beta haemolytic streptococcal infection, back pain. Cyclophosphamide dosage: N/A.
Associated medications used:
  • Morphine
  • Lorazepam
  • Ondansetron
  • Soma
  • Dexamethasone
  • Dronabinol
  • Gabapentin
  • Triamcinolone Cream
Patient was hospitalized.

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Keep Track of Side Effects

Note Your Observations

It is really important to keep of your symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:

     

    Side Effects

    Scale

    Date & Time

    Other Medicine(s) or Treatment(s)

     

     

     

     

    Scale: 1 = very mild to 10 = very bad


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  • You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Discuss Cyclophospham Side Effects

    Did You Have a Cyclophospham Side Effect?

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    Yes, Moderate
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    How Effective is Cyclophospham for You?

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    Effective
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    Safety Alerts, Active Ingredients, Usage Information

    Alternative CYCLOPHOSPHAM Names:CYCLOPHOS

    Active Ingredient: CYCLOPHOS

    More About Cyclophospham

    Side Effects reported to FDA: 4915

    Cyclophospham safety alerts: No

    Reported deaths: 945

    Reported hospitalizations: 2610

    Latest Cyclophospham clinical trials