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Cytosine Side Effects submitted to FDA

Total Cytosine reports: 7.
Cytosine FDA safety alerts: No.
   Reported hospitalizations: 6.
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FDA Reported Cytosine Side Effects: spinal compression fracture, osteoporosis, osteonecrosis, blood triglycerides increased, blood cholesterol increased, thoracic vertebral fracture, refusal of treatment by patient, lumbar vertebral fracture, pain in extremity, pyrexia, oesophageal ulcer,
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Cytosine Side Effects Report #5567371-4
Health Professional from UNITED KINGDOM reported CYTOSINE problem on Dec 07, 2007. Male patient, 43 years of age, was diagnosed with burkitt's lymphoma, acquired immunodeficiency syndrome and was treated with CYTOSINE. After drug was administered, patient experienced the following problems/side effects: blood cholesterol increased, blood triglycerides increased, osteonecrosis, osteoporosis, refusal of treatment by patient, spinal compression fracture. CYTOSINE dosage: unknown. During the same period patient was treated with DOXORUBICIN, METHOTREXATE, VINCRISTINE, HYDROCORTISONE, CYCLOPHOSPHAMIDE, PREDNISOLONE, RITONAVIR, SAQUINAVIR. Patient was hospitalized. Patient recovered.



Cytosine Side Effects Report #5578521-8
CYTOSINE problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Dec 14, 2007. Male patient, 43 years of age, was diagnosed with burkitt's lymphoma, acquired immunodeficiency syndrome and was treated with CYTOSINE. After drug was administered, patient experienced the following problems/side effects: blood cholesterol increased, blood triglycerides increased, osteonecrosis, osteoporosis, refusal of treatment by patient, spinal compression fracture. CYTOSINE dosage: unknown. During the same period patient was treated with DOXORUBICIN, METHOTREXATE, VINCRISTINE, HYDROCORTISONE, CYCLOPHOSPHAMIDE, PREDNISOLONE, RITONAVIR, SAQUINAVIR. Patient was hospitalized. Patient recovered.



Cytosine Side Effects Report #5480918-1
Consumer or non-health professional from UNITED KINGDOM reported CYTOSINE problem on Sept 24, 2007. Male patient, 43 years of age, was diagnosed with burkitt's lymphoma, acquired immunodeficiency syndrome and was treated with CYTOSINE. After drug was administered, patient experienced the following problems/side effects: blood cholesterol increased, blood triglycerides increased, osteonecrosis, osteoporosis, spinal compression fracture. CYTOSINE dosage: unknown. During the same period patient was treated with DOXORUBICIN, METHOTREXATE, VINCRISTINE, HYDROCORTISONE, CYCLOPHOSPHAMIDE, PREDNISOLONE, RITONAVIR, SAQUINAVIR. Patient was hospitalized. Patient recovered.



Cytosine Side Effects Report #5737880-3
CYTOSINE problem was reported by a Physician from KOREA, REPUBLIC OF on Apr 29, 2008. Female patient, 25 years of age, was treated with CYTOSINE. After drug was administered, patient experienced the following problems/side effects: areflexia, paraplegia, urinary retention. CYTOSINE dosage: 40 MG ONCE IT. During the same period patient was treated with METHOTREXATE, HYDROCORTISONE, MERCAPTOPURINE, PREDNISOLONE. Patient recovered.




Cytosine Side Effects Report #5313455-5
Consumer or non-health professional from UNITED KINGDOM reported CYTOSINE problem on Apr 12, 2007. Male patient, 43 years of age, was diagnosed with burkitt's lymphoma, acquired immunodeficiency syndrome and was treated with CYTOSINE. After drug was administered, patient experienced the following problems/side effects: blood cholesterol increased, blood triglycerides increased, lumbar vertebral fracture, osteonecrosis, osteoporosis, refusal of treatment by patient, spinal compression fracture, thoracic vertebral fracture. CYTOSINE dosage: unknown. During the same period patient was treated with DOXORUBICIN, METHOTREXATE, VINCRISTINE, HYDROCORTISONE, CYCLOPHOSPHAMIDE, PREDNISOLONE, RITONAVIR, SAQUINAVIR. Patient was hospitalized. Patient recovered.



Cytosine Side Effects Report #5264373-2
CYTOSINE problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Feb 21, 2007. Male patient, 43 years of age, was diagnosed with burkitt's lymphoma, acquired immunodeficiency syndrome and was treated with CYTOSINE. After drug was administered, patient experienced the following problems/side effects: blood cholesterol increased, blood triglycerides increased, osteonecrosis, osteoporosis, spinal compression fracture. CYTOSINE dosage: unknown. During the same period patient was treated with DOXORUBICIN, METHOTREXATE, VINCRISTINE, HYDROCORTISONE, CYCLOPHOSPHAMIDE, PREDNISOLONE, RITONAVIR, SAQUINAVIR. Patient was hospitalized. Patient recovered.



Cytosine Side Effects Report #5284435-3
Consumer or non-health professional from UNITED KINGDOM reported CYTOSINE problem on Mar 12, 2007. Male patient, 43 years of age, was diagnosed with burkitt's lymphoma and was treated with CYTOSINE. After drug was administered, patient experienced the following problems/side effects: blood cholesterol increased, blood triglycerides increased, lumbar vertebral fracture, osteonecrosis, osteoporosis, pain in extremity, refusal of treatment by patient, spinal compression fracture, thoracic vertebral fracture. CYTOSINE dosage: unknown. During the same period patient was treated with DOXORUBICIN, CYTARABINE, TRIMETHOPRIM, METHOTREXATE, VINCRISTINE, HYDROCORTISONE, CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient recovered.




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, Cytosine was diagnosed with burkitt's lymphoma, acquired immunodeficiency syndrome and Cytosine was diagnosed with burkitt's lymphoma, acquired immunodeficiency syndrome and