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Daflon Side Effects

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Common Daflon Side Effects


The most commonly reported Daflon side effects (click to view or check a box to report):

Fall (4)
Erythema (3)
Pruritus (3)
Oedema Peripheral (2)
Burning Sensation (2)
Gingival Oedema (2)
Gingivitis (2)
Myocardial Infarction (2)
Decreased Appetite (2)
Cholelithiasis (1)
Cough (1)
Death (1)
Cholecystitis (1)
Cyanosis (1)
Bullous Lung Disease (1)
Blood Urea Increased (1)
Carpal Tunnel Syndrome (1)
Blood Pressure Decreased (1)
Blood Creatinine Increased (1)
Klebsiella Infection (1)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Daflon Side Effects Reported to FDA



Daflon Side Effect Report#8400563-5
Pruritus, Rash Maculo-papular, Rash Erythematous, Urticaria, Idiopathic Urticaria
This is a report of a 71-year-old female patient (weight: NA) from France, suffering from the following health symptoms/conditions: NA, who was treated with Daflon (dosage: Unk, start time:
Aug 22, 2009), combined with:
  • Metformin Hcl (500 Mg, Tid, Unk)
  • Heparin (Unk)
  • Visipaque (Unk)
  • Ebastine (Unk)
  • Loprazolam Mesilate (Unk)
  • Macrogol (Unk)
  • Betadine (Unk)
  • Repaglinide (0.5 Mg, Tid , Unk)
and developed a serious reaction and side effect(s): Pruritus, Rash Maculo-papular, Rash Erythematous, Urticaria, Idiopathic Urticaria after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Daflon treatment in female patients, resulting in Pruritus side effect. The patient was hospitalized.
Daflon Side Effect Report#8250959-X
Neutropenia
This report suggests a potential Daflon Neutropenia side effect(s) that can have serious consequences. A 65-year-old female patient (weight: NA) from France was diagnosed with the following symptoms/conditions: NA and used Daflon (dosage: NA) starting
Nov 04, 2011. After starting Daflon the patient began experiencing various side effects, including: NeutropeniaAdditional drugs used concurrently:
  • Mycophenolate Mofetil (cellcept)
  • Levothyroxine Sodium
  • Lopressor
  • Plaquenil
  • Corticosteroids
  • Lasix
  • Potassium Chloride
  • Eupressyl
The patient was hospitalized. Although Daflon demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Neutropenia, may still occur.
Daflon Side Effect Report#8220766-2
Glaucoma
This Glaucoma problem was reported by a health professional from Brazil. A 77-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Jan 01, 2007 this consumer started treatment with Daflon (dosage: NA). The following drugs were being taken at the same time:
  • Vitamin B Complex Cap
  • Autopen 24
  • Warfarin Sodium (1/4 Tablet Daily)
  • Lantus
  • Multivitamin
  • Humalog (Dose: According To Glycemia)
  • Sertraline Hydrochloride
When using Daflon, the patient experienced the following unwanted symptoms/side effects: GlaucomaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Glaucoma, may become evident only after a product is in use by the general population.
Daflon Side Effect Report#8173399-0
Burning Sensation, Adverse Reaction, Pruritus, Gingivitis, Erythema, Gingival Oedema
This Burning Sensation side effect was reported by a pharmacist from Portugal. A 81-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Daflon 500 (drug dosage: NA), which was initiated on
Dec 03, 2011. Concurrently used drugs:
  • Trental
  • Clopidogrel
.After starting to take Daflon 500 the consumer reported adverse symptoms, such as: Burning Sensation, Adverse Reaction, Pruritus, Gingivitis, Erythema, Gingival OedemaThese side effects may potentially be related to Daflon 500.
Daflon Side Effect Report#8171994-6
Myocardial Infarction
This is a report of a 92-year-old female patient (weight: NA) from Venezuela, suffering from the following health symptoms/conditions: NA, who was treated with Daflon (dosage: NA, start time:
Jan 01, 2010), combined with:
  • Lipitor (20 Mg, 1x/day)
  • Levothyroxine Sodium
  • Omeprazole (20 Mg, 1x/day)
and developed a serious reaction and side effect(s): Myocardial Infarction after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Daflon treatment in female patients, resulting in Myocardial Infarction side effect.
Daflon Side Effect Report#8153702-8
Nicotine Dependence, Cough, Adverse Event
This report suggests a potential Daflon Nicotine Dependence side effect(s) that can have serious consequences. A female patient (weight: NA) from Brazil was diagnosed with the following symptoms/conditions: cardiovascular disorder,blood cholesterol increased,arthritis and used Daflon (dosage: NA) starting
Jan 01, 2007. After starting Daflon the patient began experiencing various side effects, including: Nicotine Dependence, Cough, Adverse EventAdditional drugs used concurrently:
  • Crestor
  • Glucocorticoid
  • Arava
  • Procoralan
  • Synthroid
  • Nicorette (6gum Per Day)
  • Diovan Hct
  • Omega 3-6-9
The patient was hospitalized. Although Daflon demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Nicotine Dependence, may still occur.
Daflon Side Effect Report#8111641-2
Gingivitis, Pruritus, Abasia, Burning Sensation, Erythema, Insomnia, Gingival Oedema
This Gingivitis problem was reported by a pharmacist from Portugal. A 81-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Dec 03, 2011 this consumer started treatment with Daflon 500 (dosage: NA). The following drugs were being taken at the same time:
  • Trental
  • Clopidogrel
When using Daflon 500, the patient experienced the following unwanted symptoms/side effects: Gingivitis, Pruritus, Abasia, Burning Sensation, Erythema, Insomnia, Gingival OedemaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Gingivitis, may become evident only after a product is in use by the general population.
Daflon Side Effect Report#7794583-1
Urinary Tract Infection, Nephrolithiasis, Oedema Peripheral, Wrist Fracture, Pain In Extremity, Fall, Dysgeusia, Hunger
This Urinary Tract Infection side effect was reported by a consumer or non-health professional from Brazil. A female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Daflon (drug dosage: NA), which was initiated on NS. Concurrently used drugs:
  • Enalapril Maleate
  • Forteo (20 Ug, Qd)
  • Sinvastatina
.After starting to take Daflon the consumer reported adverse symptoms, such as: Urinary Tract Infection, Nephrolithiasis, Oedema Peripheral, Wrist Fracture, Pain In Extremity, Fall, Dysgeusia, HungerThese side effects may potentially be related to Daflon. The patient was hospitalized.
Daflon Side Effect Report#7720908-9
Electrocardiogram Q Wave Abnormal, Somnolence, Adjustment Disorder, Haemorrhoids, Lower Gastrointestinal Haemorrhage, Ventricular Extrasystoles, Diverticulum Intestinal, Decreased Appetite, Scoliosis
This is a report of a 86-year-old male patient (weight: NA) from Singapore, suffering from the following health symptoms/conditions: NA, who was treated with Daflon (diosmin) (dosage: NA, start time:
Mar 31, 2011), combined with:
  • Enalapril Maleate
and developed a serious reaction and side effect(s): Electrocardiogram Q Wave Abnormal, Somnolence, Adjustment Disorder, Haemorrhoids, Lower Gastrointestinal Haemorrhage, Ventricular Extrasystoles, Diverticulum Intestinal, Decreased Appetite, Scoliosis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Daflon (diosmin) treatment in male patients, resulting in Electrocardiogram Q Wave Abnormal side effect. The patient was hospitalized.
Daflon Side Effect Report#7658758-4
Decreased Appetite, Hypothyroidism, Disorientation
This report suggests a potential Daflon Decreased Appetite side effect(s) that can have serious consequences. A 56-year-old female patient (weight: NA) from Spain was diagnosed with the following symptoms/conditions: NA and used Daflon (dosage: NA) starting
Mar 15, 2011. After starting Daflon the patient began experiencing various side effects, including: Decreased Appetite, Hypothyroidism, DisorientationAdditional drugs used concurrently:
  • Espidifen
  • Nolotil /spa/
  • Seroxat ^ciba-geigy^
  • Zolpidem
  • Aldactone
  • Pantoprazole
  • Sutent (50 Mg, 1x/day)
  • Norvasc
Although Daflon demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Decreased Appetite, may still occur.
Daflon Side Effect Report#7584682-1
Fall
This Fall problem was reported by a physician from Egypt. A 66-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: haemorrhoids. On NS this consumer started treatment with Daflon (dosage: 500 Mg, 2x/day). The following drugs were being taken at the same time:
  • Isosorbide Dinitrate (5 Mg, 1x/day)
  • Cardura (4 Mg, 1x/day)
  • Procto-glyvenol (Unk)
When using Daflon, the patient experienced the following unwanted symptoms/side effects: FallAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Fall, may become evident only after a product is in use by the general population.
Daflon Side Effect Report#7525767-5
Respiratory Disorder
This Respiratory Disorder side effect was reported by a consumer or non-health professional from Brazil. A male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Daflon (drug dosage: 500, Unk), which was initiated on
Aug 01, 2010. Concurrently used drugs:
  • Exelon (Unk)
.After starting to take Daflon the consumer reported adverse symptoms, such as: Respiratory DisorderThese side effects may potentially be related to Daflon. The patient was hospitalized.
Daflon Side Effect Report#7484151-3
Carpal Tunnel Syndrome, Limb Injury
This is a report of a female patient (weight: NA) from Brazil, suffering from the following health symptoms/conditions: varicose vein,osteoarthritis, who was treated with Daflon (dosage: Unk, Qd, start time:
May 01, 2008), combined with:
  • Glucosamine Sulfate (Unk, Qd)
  • Natrilix (10 Mg, Qd)
  • Cymbalta (60 Mg, Qd)
  • Diovan (80 Mg, Qd)
and developed a serious reaction and side effect(s): Carpal Tunnel Syndrome, Limb Injury after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Daflon treatment in female patients, resulting in Carpal Tunnel Syndrome side effect. The patient was hospitalized.
Daflon Side Effect Report#7419158-5
Lymphoedema, Aortic Aneurysm
This report suggests a potential Daflon Lymphoedema side effect(s) that can have serious consequences. A 87-year-old male patient (weight: NA) from Belgium was diagnosed with the following symptoms/conditions: NA and used Daflon (dosage: Unk) starting
Jun 02, 2009. After starting Daflon the patient began experiencing various side effects, including: Lymphoedema, Aortic AneurysmAdditional drugs used concurrently:
  • Cymbalta (Unk)
  • Zocor (20 Mg, 1x/day)
  • Bisoprolol (10 Mg, 1x/day)
  • Sintrom (Unk)
  • Lyrica (150 Mg, 2x/day)
  • Lasix (Unk)
Although Daflon demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Lymphoedema, may still occur.
Daflon Side Effect Report#7328166-4
Femur Fracture, Fall
This Femur Fracture problem was reported by a physician from Spain. A female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Oct 10, 2009 this consumer started treatment with Daflon (dosage: 500 Mg, Daily (1/d)). The following drugs were being taken at the same time:
  • Forteo (20 Ug, Daily (1/d))
  • Omeprazole (20 Mg, Daily (1/d))
  • Atorvastatina (40 Mg, Daily (1/d))
  • Micardis
When using Daflon, the patient experienced the following unwanted symptoms/side effects: Femur Fracture, FallThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Femur Fracture, may become evident only after a product is in use by the general population.
Daflon Side Effect Report#7300434-1
Anaemia, Salivary Hypersecretion, Quadriparesis, Enterobacter Infection, Monoparesis, Klebsiella Infection, Leukocyturia, Musculoskeletal Pain
This Anaemia side effect was reported by a physician from Poland. A female patient (weight:NA) experienced the following symptoms/conditions: phlebitis.The patient was prescribed Daflon (diosmin) (drug dosage: NA), which was initiated on
Mar 18, 2009. Concurrently used drugs:
  • Fraxiparina
  • Omeprazole
  • Mizodin
  • Fty 720 (No Treatment)
  • Tritace
  • Fty 720
  • Lactulose
  • Fty 720
.After starting to take Daflon (diosmin) the consumer reported adverse symptoms, such as: Anaemia, Salivary Hypersecretion, Quadriparesis, Enterobacter Infection, Monoparesis, Klebsiella Infection, Leukocyturia, Musculoskeletal PainThese side effects may potentially be related to Daflon (diosmin). The patient was hospitalized.
Daflon Side Effect Report#7236456-9
Oedema Peripheral, Cholecystitis, Cholelithiasis, Cyanosis, Erythema
This is a report of a female patient (weight: NA) from Spain, suffering from the following health symptoms/conditions: cardiovascular insufficiency,hypersensitivity,osteoporosis, who was treated with Daflon (dosage: 1000 Mg, Daily (1/d), start time:
Oct 19, 2010), combined with:
  • Ebastine (10 Mg, Daily (1/d))
  • Ideos (2 D/f, Daily (1/d))
  • Forteo (20 Ug, Daily (1/d))
  • Pariet (20 Mg, Daily (1/d))
  • Torsemide (5 Mg, Daily (1/d))
and developed a serious reaction and side effect(s): Oedema Peripheral, Cholecystitis, Cholelithiasis, Cyanosis, Erythema after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Daflon treatment in female patients, resulting in Oedema Peripheral side effect. The patient was hospitalized.
Daflon Side Effect Report#5630110-2
Myocardial Infarction
This report suggests a potential Daflon (diosmin) Myocardial Infarction side effect(s) that can have serious consequences. A 56-year-old female patient (weight: NA) from France was diagnosed with the following symptoms/conditions: phlebitis,chronic myeloid leukaemia and used Daflon (diosmin) (dosage: NA) starting
Dec 07, 2005. After starting Daflon (diosmin) the patient began experiencing various side effects, including: Myocardial InfarctionAdditional drugs used concurrently:
  • Amn107 (400 Mg, Bid)
The patient was hospitalized. Although Daflon (diosmin) demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Myocardial Infarction, may still occur.
Daflon Side Effect Report#5084996-3
Eosinophilia, Renal Failure Acute, Toxic Skin Eruption
This Eosinophilia problem was reported by a health professional from France. A 73-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: ill-defined disorder. On
May 24, 2006 this consumer started treatment with Daflon (dosage: NA). The following drugs were being taken at the same time:
  • Coversyl (Daily Dose: 4 Milligram(s))
  • Allopurinol
  • Amlodipine Besylate (Daily Dose: 10 Milligram(s))
  • Asasantin
When using Daflon, the patient experienced the following unwanted symptoms/side effects: Eosinophilia, Renal Failure Acute, Toxic Skin EruptionThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Eosinophilia, may become evident only after a product is in use by the general population.
Daflon Side Effect Report#4955315-5
Anorexia, Asthenia, Balance Disorder, Blood Creatinine Increased, Blood Pressure Decreased, Blood Urea Increased, Fall, Hypotension
This Anorexia side effect was reported by a consumer or non-health professional from France. A 50-year-old male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Daflon 500 (drug dosage: NA), which was initiated on NS. Concurrently used drugs:
  • Motilium (30 Mg/day)
  • Equanil (750 Mg/day)
  • Vastarel (60 Mg/day)
  • Seresta (100 Mg/day)
  • Euphytose (3 Df/day)
  • Solian (200 Mg, Bid)
  • Cotareg (1 Df, Qd)
  • Vitamin B1 (+b6)
.After starting to take Daflon 500 the consumer reported adverse symptoms, such as: Anorexia, Asthenia, Balance Disorder, Blood Creatinine Increased, Blood Pressure Decreased, Blood Urea Increased, Fall, HypotensionThese side effects may potentially be related to Daflon 500. The patient was hospitalized.
Daflon Side Effect Report#4852373-3
Bullous Lung Disease, Dyspnoea Exertional, Interstitial Lung Disease, Pulmonary Eosinophilia
This is a report of a male patient (weight: NA) from France, suffering from the following health symptoms/conditions: NA, who was treated with Daflon (dosage: Unk, Unk, start time:
May 03, 2004), combined with:
  • Fractal (80 Mg, Qd)
and developed a serious reaction and side effect(s): Bullous Lung Disease, Dyspnoea Exertional, Interstitial Lung Disease, Pulmonary Eosinophilia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Daflon treatment in male patients, resulting in Bullous Lung Disease side effect.



The appearance of Daflon on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

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Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Daflon reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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