Dasatinib Safety Questions, Dasatinib Answers
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Dasatinib Safety Reports
Total Dasatinib reports: 229.Dasatinib FDA safety alerts: No.
Reported deaths: 82 Reported hospitalizations: 160.
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Reported Dasatinib Side Effects: pleural effusion, malignant neoplasm progression, pyrexia, respiratory failure, dyspnoea, chronic myeloid leukaemia, pneumonia, dyspnoea exertional, hypoxia, vomiting, infection.
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Showing 1-50 of 229 Next >
Dasatinib Side Effects Report #5270084-XConsumer or non-health professional from FINLAND reported DASATINIB problem on Mar 20, 2007. Male patient, 70 years of age, was diagnosed with chronic myeloid leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: cardiac failure, chronic myeloid leukaemia, dyspnoea, malignant neoplasm progression. DASATINIB dosage: 70MG FROM 24-NOV-05 - 23-DEC-05; 0MG FROM 24-DEC-05 - 26-JAN-06; 40 MG FROM 23-JUN-06-05-NOV-06. Patient was hospitalized. Patient died on 11/14/2006.
Dasatinib Side Effects Report #5272835-7
DASATINIB problem was reported by a Consumer or non-health professional from FINLAND on Mar 21, 2007. Male patient, 70 years of age, was diagnosed with chronic myeloid leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: cardiac failure, chronic myeloid leukaemia, dyspnoea, malignant neoplasm progression. DASATINIB dosage: 70MG FROM 24-NOV-05 - 23-DEC-05; 0MG FROM 24-DEC-05 - 26-JAN-06; 40 MG FROM 23-JUN-06-05-NOV-06. Patient was hospitalized. Patient died on 11/14/2006.
Dasatinib Side Effects Report #5276822-4
Health Professional from ITALY reported DASATINIB problem on Mar 20, 2007. Female patient, 74 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: pulmonary oedema. DASATINIB dosage: unknown. Patient died.
Dasatinib Side Effects Report #5278415-1
DASATINIB problem was reported by a Consumer or non-health professional from GERMANY on Mar 23, 2007. Female patient, 69 years of age, was diagnosed with chronic myeloid leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: hyperkalaemia. DASATINIB dosage: unknown. During the same period patient was treated with SPIRONOLACTONE. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5283757-X
Consumer or non-health professional from UNITED KINGDOM reported DASATINIB problem on Mar 29, 2007. Male patient, child 2 years of age, was diagnosed with leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: febrile neutropenia, hypocalcaemia, hypomagnesaemia. DASATINIB dosage: unknown. During the same period patient was treated with AMBISOME, MEROPENEM, TEICOPLANIN. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5289707-4
DASATINIB problem was reported by a Health Professional from ITALY on Apr 05, 2007. Female patient, 70 years of age, was diagnosed with malignant melanoma and was treated with DASATINIB. DASATINIB dosage: unknown. During the same period patient was treated with COUMADIN. Patient died on 03/27/2007.
Dasatinib Side Effects Report #5289725-6
Health Professional from KOREA, REPUBLIC OF reported DASATINIB problem on Apr 05, 2007. Female patient, 68 years of age, was diagnosed with chronic myeloid leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: diarrhoea. DASATINIB dosage: unknown. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5290525-1
DASATINIB problem was reported by a Health Professional from UNITED STATES on Apr 04, 2007. Female patient, 46 years of age, weighting 205.0 lb, was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: atelectasis, chest pain, pleural effusion. DASATINIB dosage: unknown. Patient recovered.
Dasatinib Side Effects Report #5292188-8
Health Professional from FRANCE reported DASATINIB problem on Apr 04, 2007. Female patient, 49 years of age, was diagnosed with chronic myeloid leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: pyoderma gangrenosum. DASATINIB dosage: unknown. During the same period patient was treated with FLECAINIDE ACETATE. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5292236-5
DASATINIB problem was reported by a Health Professional from BELGIUM on Apr 06, 2007. Female patient, 57 years of age, was diagnosed with leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: pleural effusion. DASATINIB dosage: unknown. During the same period patient was treated with ALLOPURINOL, IBUPROFEN, FUROSEMIDE. Patient recovered.
Dasatinib Side Effects Report #5295677-5
Pharmacist from UNITED STATES reported DASATINIB problem on Apr 10, 2007. Female patient, weighting 219.6 lb, was diagnosed with acute lymphocytic leukaemia, chromosome analysis abnormal and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: acute lymphocytic leukaemia, cardiac failure congestive, condition aggravated, pulmonary hypertension. DASATINIB dosage: unknown. Patient recovered.
Dasatinib Side Effects Report #5296487-5
DASATINIB problem was reported by a Health Professional from ITALY on Apr 12, 2007. Male patient, 55 years of age, was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: bronchopneumonia, epistaxis. DASATINIB dosage: unknown. During the same period patient was treated with VORICONAZOLE. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5299418-7
Health Professional from UNITED STATES reported DASATINIB problem on Apr 11, 2007. Female patient, 56 years of age, was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: cardiomyopathy, dyspnoea, respiratory failure. DASATINIB dosage: 21APR05 70MGTWICEDAILY;18JUL06TO26MAR07 60MGDAILY;27MAR07 80MGDAILY;09APR07 60MG DAILY;10APR07 DISC.. During the same period patient was treated with SPIRONOLACTONE, LISINOPRIL, FELODIPINE, CATAPRES, FUROSEMIDE, ACYCLOVIR, ALLOPURINOL, CHLORHEXIDINE GLUCONATE. Patient died on 04/11/2007.
Dasatinib Side Effects Report #5301662-7
DASATINIB problem was reported by a Health Professional from SWEDEN on Apr 16, 2007. Male patient, 17 years of age, was diagnosed with leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: infection, pleural effusion. DASATINIB dosage: unknown. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5304729-2
Health Professional from UNITED KINGDOM reported DASATINIB problem on Apr 20, 2007. Male patient, 52 years of age, was diagnosed with leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: anaemia, diarrhoea, neutropenic sepsis, pleural effusion, urinary tract infection, vomiting. DASATINIB dosage: unknown. During the same period patient was treated with METOCLOPRAMIDE, PAROXETINE, ORAMORPH, PARACETAMOL, DIHYDROCODEINE BITARTRATE. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5306925-7
DASATINIB problem was reported by a Health Professional from ITALY on Apr 24, 2007. Female patient, 56 years of age, was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: diverticulitis. DASATINIB dosage: unknown. Patient recovered.
Dasatinib Side Effects Report #5307281-0
Health Professional from CANADA reported DASATINIB problem on Apr 13, 2007. Male patient, 63 years of age, was diagnosed with chronic myeloid leukaemia, cough and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: lymphoma. DASATINIB dosage: unknown. During the same period patient was treated with GAVISCON, SALOFALK, ANUSOL HC, COLACE, METAMUCIL, HYDROCORTISONE CREAM, PULMICORT. Patient recovered.
Dasatinib Side Effects Report #5308480-4
DASATINIB problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Apr 20, 2007. Male patient, child 2 years of age, was diagnosed with leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: anorexia, caecitis, febrile neutropenia, hypocalcaemia, hypomagnesaemia. DASATINIB dosage: unknown. During the same period patient was treated with AMBISOME, MEROPENEM, TEICOPLANIN, PARACETAMOL, DIHYDROCODEINE BITARTRATE, CHLORPHENIRAMINE MALEATE, ONDANSETRON. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5308482-8
Consumer or non-health professional from JAPAN reported DASATINIB problem on Apr 18, 2007. Male patient, 49 years of age, weighting 174.2 lb, was diagnosed with leukaemia, pyrexia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: disseminated intravascular coagulation, hypoxia, pneumonia, pulmonary haemorrhage, pyrexia. DASATINIB dosage: unknown. During the same period patient was treated with LOXONIN. Patient was hospitalized. Patient died on 02/17/2007.
Dasatinib Side Effects Report #5310245-4
DASATINIB problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 25, 2007. Female patient, 55 years of age, was diagnosed with breast cancer and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: blood chloride decreased, blood sodium decreased, dehydration, diarrhoea, nausea, vomiting, white blood cell count increased. DASATINIB dosage: unknown. During the same period patient was treated with BENACEN, HYDROCHLOROTHIAZIDE. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5310334-4
Health Professional from ITALY reported DASATINIB problem on Apr 24, 2007. Female patient, 70 years of age, was diagnosed with malignant melanoma and was treated with DASATINIB. DASATINIB dosage: unknown. During the same period patient was treated with COUMADIN. Patient died on 03/27/2007.
Dasatinib Side Effects Report #5311128-6
DASATINIB problem was reported by a Health Professional from PORTUGAL on Apr 26, 2007. Female patient, 76 years of age, was diagnosed with chronic myeloid leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: cardiac failure, cardio-respiratory arrest, lung infection, malignant neoplasm progression, pericardial effusion, pleural effusion, respiratory distress. DASATINIB dosage: unknown. During the same period patient was treated with INTERFERON, HYDROXYUREA, BUSULFAN. Patient died on 03/23/2007.
Dasatinib Side Effects Report #5311859-8
Health Professional from UNITED STATES reported DASATINIB problem on Apr 27, 2007. Female patient, 76 years of age, weighting 176.4 lb, was diagnosed with chronic myeloid leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: asthenia, blood count, dyspnoea exertional, fatigue, pancytopenia, wound. DASATINIB dosage: 50MG BID PO. During the same period patient was treated with HYDROXYUREA. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5312620-0
DASATINIB problem was reported by a Health Professional from UNITED STATES on Apr 19, 2007. Female patient, 56 years of age, was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: acute coronary syndrome, cardiogenic shock, cardiomyopathy, dyspnoea, pulmonary hypertension, respiratory failure. DASATINIB dosage: 21APR05 70MGTWICEDAILY;18JUL06TO26MAR07 60MGDAILY;27MAR07 80MGDAILY;09APR07 60MG DAILY;10APR07 DISC.. During the same period patient was treated with SPIRONOLACTONE, LISINOPRIL, FELODIPINE, CATAPRES, FUROSEMIDE, ACYCLOVIR, ALLOPURINOL, CHLORHEXIDINE GLUCONATE. Patient was hospitalized. Patient died on 04/11/2007.
Dasatinib Side Effects Report #5312755-2
Consumer or non-health professional from JAPAN reported DASATINIB problem on Apr 26, 2007. Male patient, 49 years of age, weighting 174.2 lb, was diagnosed with leukaemia, pyrexia, pneumonia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: disseminated intravascular coagulation, hypoxia, pneumonia, pulmonary haemorrhage, pyrexia. DASATINIB dosage: 140MG DAILY 08-DEC-06 TO 26-DEC-06, 100MG DAILY 12-JAN-2007 TO 12-JAN-07, RESTARTED 15-JAN-07. During the same period patient was treated with LOXONIN, GAMIMUNE N, MAXIPIME, MEROPEN, MINOCYCLINE, FUNGUARD, VFEND, DENOSINE. Patient was hospitalized. Patient died on 02/17/2007.
Dasatinib Side Effects Report #5313795-X
DASATINIB problem was reported by a Health Professional from ITALY on Apr 27, 2007. Female patient, 79 years of age, was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: septic shock. DASATINIB dosage: unknown. Patient was hospitalized. Patient died on 04/23/2007.
Dasatinib Side Effects Report #5315482-0
Health Professional from CANADA reported DASATINIB problem on May 01, 2007. Male patient, 64 years of age, was diagnosed with chronic myeloid leukaemia, cough and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: lymphoma. DASATINIB dosage: unknown. During the same period patient was treated with GAVISCON, SALOFALK, ANUSOL HC, COLACE, METAMUCIL, HYDROCORTISONE CREAM, PULMICORT. Patient recovered.
Dasatinib Side Effects Report #5318973-1
DASATINIB problem was reported by a Health Professional from UNITED STATES on May 03, 2007. Female patient, 68 years of age, was diagnosed with polycythaemia vera and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: acute respiratory distress syndrome, dyspnoea, lung infiltration, nausea, vomiting, white blood cell count increased. DASATINIB dosage: unknown. During the same period patient was treated with HYDREA, COUMADIN, FOLIC ACID, VITAMIN B. Patient was hospitalized. Patient died on 05/02/2007.
Dasatinib Side Effects Report #5321311-1
Consumer or non-health professional from UNITED STATES reported DASATINIB problem on May 08, 2007. Male patient, 58 years of age, was diagnosed with leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: pleural effusion. DASATINIB dosage: unknown. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5322698-6
DASATINIB problem was reported by a Consumer or non-health professional from UNITED KINGDOM on May 10, 2007. Male patient, child 2 years of age, was diagnosed with leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: abdominal pain, anorexia, caecitis, febrile neutropenia, hypocalcaemia, hypomagnesaemia, musculoskeletal pain. DASATINIB dosage: unknown. During the same period patient was treated with AMBISOME, MEROPENEM, TEICOPLANIN, PARACETAMOL, DIHYDROCODEINE BITARTRATE, CHLORPHENIRAMINE MALEATE, ONDANSETRON. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5322759-1
Consumer or non-health professional from BELGIUM reported DASATINIB problem on May 10, 2007. Female patient, 68 years of age, was diagnosed with breast cancer and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: dehydration, renal failure acute, vomiting. DASATINIB dosage: unknown. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5326482-9
DASATINIB problem was reported by a Consumer or non-health professional from BELGIUM on May 15, 2007. Female patient, 68 years of age, was diagnosed with breast cancer and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: dehydration, renal failure acute, vomiting. DASATINIB dosage: unknown. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5328542-5
Consumer or non-health professional from UNITED STATES reported DASATINIB problem on May 15, 2007. Female patient, 55 years of age, was diagnosed with breast cancer and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: dehydration, diarrhoea, nausea, vomiting. DASATINIB dosage: unknown. During the same period patient was treated with BENACEN, HYDROCHLOROTHIAZIDE. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5338185-5
DASATINIB problem was reported by a Health Professional from FRANCE on May 25, 2007. Female patient, 55 years of age, was diagnosed with breast cancer and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: haemoptysis, respiratory failure. DASATINIB dosage: unknown. During the same period patient was treated with DURAGESIC. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5341668-5
Health Professional from FRANCE reported DASATINIB problem on May 30, 2007. Female patient, 55 years of age, was diagnosed with breast cancer and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: haemoptysis, myopericarditis, respiratory failure. DASATINIB dosage: unknown. During the same period patient was treated with DURAGESIC. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5343713-X
DASATINIB problem was reported by a Health Professional from UNITED STATES on May 29, 2007. Male patient, 43 years of age, was diagnosed with chronic myeloid leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: hypovolaemic shock, multi-organ failure, venous occlusion. DASATINIB dosage: unknown. Patient died on 05/18/2007.
Dasatinib Side Effects Report #5345996-9
Consumer or non-health professional from ITALY reported DASATINIB problem on May 29, 2007. Male patient, 36 years of age, was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: febrile neutropenia, septic shock. DASATINIB dosage: unknown. Patient died on 05/07/2007.
Dasatinib Side Effects Report #5349712-6
DASATINIB problem was reported by a Health Professional from CANADA on June 06, 2007. Female patient, 56 years of age, was diagnosed with chronic myeloid leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: gastrointestinal haemorrhage. DASATINIB dosage: unknown. Patient died on 05/31/2007.
Dasatinib Side Effects Report #5349714-X
Consumer or non-health professional from UNITED KINGDOM reported DASATINIB problem on June 04, 2007. Male patient, child 2 years of age, was diagnosed with leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: abdominal pain, anorexia, caecitis, febrile neutropenia, hypocalcaemia, hypomagnesaemia, musculoskeletal pain. DASATINIB dosage: unknown. During the same period patient was treated with AMBISOME, MEROPENEM, TEICOPLANIN, PARACETAMOL, DIHYDROCODEINE BITARTRATE, CHLORPHENIRAMINE MALEATE, ONDANSETRON. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5350547-9
DASATINIB problem was reported by a Health Professional from FRANCE on June 07, 2007. Female patient, 58 years of age, was diagnosed with chronic myeloid leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: osteonecrosis. DASATINIB dosage: unknown. During the same period patient was treated with IMATINIB MESYLATE, GLUCOPHAGE, LEVOTHYROXINE. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5350981-7
Consumer or non-health professional from PHILIPPINES reported DASATINIB problem on May 30, 2007. Female patient, 45 years of age, was diagnosed with chronic myeloid leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: cataract. DASATINIB dosage: unknown. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5355300-8
DASATINIB problem was reported by a Pharmacist from NETHERLANDS on June 12, 2007. Male patient, child 12 years of age, was diagnosed with chronic myeloid leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: dyspnoea, haematemesis, oedema. DASATINIB dosage: unknown. During the same period patient was treated with VORICONAZOLE, ONDANSETRON, CEFTAZIDIME, TEICOPLANIN, VITAMIN K, PARACETAMOL. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5355977-7
Health Professional from UNITED STATES reported DASATINIB problem on June 08, 2007. Male patient, 43 years of age, was diagnosed with chronic myeloid leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: venous occlusion. DASATINIB dosage: unknown. Patient died on 05/18/2007.
Dasatinib Side Effects Report #5358661-9
DASATINIB problem was reported by a Health Professional from UNITED STATES on June 11, 2007. Female patient, 66 years of age, was diagnosed with colorectal cancer metastatic, pain and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, chills, hypoxia, pneumonia, pyrexia. DASATINIB dosage: unknown. During the same period patient was treated with CETUXIMAB, OXALIPLATIN, FLUOROURACIL, LEUCOVORIN CALCIUM, ALEVE, AMBIEN, DARVON, FISH OIL. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5359280-0
Health Professional from SWEDEN reported DASATINIB problem on June 13, 2007. Male patient, 40 years of age, was diagnosed with chronic myeloid leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: erysipelas. DASATINIB dosage: unknown. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5369627-7
DASATINIB problem was reported by a Consumer or non-health professional from PHILIPPINES on June 13, 2007. Female patient, 45 years of age, was diagnosed with chronic myeloid leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: cataract. DASATINIB dosage: unknown. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5370536-8
Health Professional from FRANCE reported DASATINIB problem on June 22, 2007. Female patient, 55 years of age, was diagnosed with breast cancer and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: haemoptysis, myopericarditis, respiratory failure. DASATINIB dosage: unknown. During the same period patient was treated with DURAGESIC. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5370835-X
DASATINIB problem was reported by a Health Professional from UNITED STATES on June 25, 2007. Male patient, 55 years of age, was diagnosed with non-small cell lung cancer, back pain, nausea and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: anaemia, dyspnoea, pleural effusion, rash, thrombocytopenia. DASATINIB dosage: unknown. During the same period patient was treated with CEFEPIME, DARBEPOETIN ALFA, REGLAN, NAPROXEN, ALBUTEROL, TYLENOL, PROTONIX, ZOFRAN. Patient was hospitalized. Patient recovered.
Dasatinib Side Effects Report #5371706-5
Health Professional from UNITED STATES reported DASATINIB problem on June 25, 2007. Male patient, 80 years of age, was diagnosed with colorectal cancer metastatic and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: cerebrovascular accident, pleural effusion. DASATINIB dosage: unknown. During the same period patient was treated with PROCARDIA, RESTORIL, TYLENOL. Patient was hospitalized. Patient died on 05/30/2006.
Dasatinib Side Effects Report #5374538-7
DASATINIB problem was reported by a Consumer or non-health professional from UNITED KINGDOM on June 28, 2007. Male patient, child 2 years of age, was diagnosed with leukaemia and was treated with DASATINIB. After drug was administered, patient experienced the following problems/side effects: abdominal pain, anorexia, caecitis, febrile neutropenia, hypocalcaemia, hypomagnesaemia, musculoskeletal pain. DASATINIB dosage: unknown. During the same period patient was treated with AMBISOME, MEROPENEM, TEICOPLANIN, PARACETAMOL, DIHYDROCODEINE BITARTRATE, CHLORPHENIRAMINE MALEATE, COTRIM, ONDANSETRON. Patient was hospitalized. Patient recovered.
Showing 1-50 of 229 Next >
Drug Information: Dasatinib
URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a607063.html
(da sa' ti nib)Why is this medication prescribed?
Dasatinib is used to treat certain types of leukemia (cancer that begins in the white blood cells) in people who can no longer benefit from other medications for leukemia including imatinib (Gleevec) or who cannot take these medications because of severe side effects. Dasatinib is in a class of medications called protein-tyrosine kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps stop the spread of cancer cells.
How should this medicine be used?
Dasatinib comes as a tablet to take by mouth. It is usually taken twice a day, in the morning and the evening, with or without food. Take dasatinib at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take dasatinib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Swallow the tablets whole; do not split, chew, or crush them.
Your doctor may adjust your dose of dasatinib depending on your response to treatment and any side effects that you experience. Talk to your doctor about how you are feeling during your treatment.
Continue to take dasatinib even if you feel well. Do not stop taking dasatinib without talking to your doctor.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking dasatinib,
- tell your doctor and pharmacist if you are allergic to dasatinib or any other medications.
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: alfentanil (Alfenta), anticoagulants ("blood thinners") such as warfarin (Coumadin), anthracycline medications for cancer such as daunorubicin (Cerubidine), doxorubicin (Doxil), and epirubicin (Ellence); aspirin; certain antifungals such as ketoconazole (Nizoral), and itraconazole (Sporanox); astemizole (Hismanal) (not available in the United States; cisapride (Propulsid) (not available in the United States); clarithromycin (Biaxin); dexamethasone (Decadron); cyclosporine (Sandimmune); ergot alkaloids such as ergotamine (Ergomar), and dihydroergotamine (D.H.E. 45, Migranal); erythromycin (E.E.S., E-Mycin, Erythrocin); fentanyl (Duragesic, Actiq); certain medications used to treat human immunodeficiency virus (HIV) such as atazanavir (Reyataz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), and saquinavir (Invirase); certain medications for irregular heartbeat such as amiodarone (Cordarone), disopyramide (Norpace),dofetilide (Tikosyn), flecainide (Tambocor), mexiletine (Mexitil), moricizine (Ethmozine), procainamide (Procanbid, Pronestyl), propafenone (Rythmol), quinidine (Quinidex), sotalol (Betapace, Betapace AF), and tocainide (Tonocard); medications to reduce stomach acid such as cimetidine (Tagamet®), famotidine (Pepcid), nizatidine (Axid), ranitidine (Zantac), esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), and rabeprazole (AcipHex); certain medications for seizures such as carbamazepine (Tegretol), phenobarbital (Luminal), and phenytoin (Dilantin); moxifloxacin (Avelox); nefazodone; pimozide (Orap); rifampicin (Rimactane); simvastatin (Zocor); sirolimus (Rapamune), tacrolimus (Prograf); telithromycin (Ketek); terfenadine (Seldane) (not available in the United States); and thioridazine (Mellaril). Other medications may also interact with dasatinib, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- if you are taking antacids, such as aluminium hydroxide/magnesium hydroxide (Maalox), calcium carbonate (Tums) or calcium carbonate and magnesium (Rolaids), take them 2 hours before or 2 hours after you take dasatinib.
- tell your doctor what herbal products you are taking, especially St. John's wort.
- tell your doctor if you have or have ever had lactose intolerance (inability to digest dairy products), low levels of potassium or magnesium in your blood, long QT syndrome (a heart condition that may cause dizziness, fainting, or irregular heartbeat), or liver or heart disease.
- tell your doctor if you are pregnant or plan to become pregnant, or if your partner may become pregnant. You or your partner should not become pregnant while you are taking dasatinib. You should use birth control to prevent pregnancy in yourself or your partner during your treatment with dasatinib. Talk to your doctor about birth control methods that will work for you. If you or your partner becomes pregnant while taking dasatinib, call your doctor. Dasatinib may harm the fetus.
- tell your doctor if you are breast-feeding. You should not breastfeed while you are taking dasatinib.
What special dietary instructions should I follow?
Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medicine.
What should I do if I forget a dose?
Skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
Dasatinib may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- headache
- muscle pain
- tiredness
- weakness
- dizziness
- joint pain
- pain, burning or tingling in the hands or the feet
- skin rash
- skin redness
- peeling skin
- swelling, redness and pain inside the mouth
- mouth sores
- diarrhea
- nausea
- vomiting
- constipation
- stomach pain or swelling
- loss of appetite
- weight loss
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
- fever, sore throat, chills, and other signs of infection
- swelling of the eyes, hands, arms, feet, ankles or lower legs
- sudden weight gain
- difficulty breathing, especially when lying down
- coughing up pink or bloody mucus
- dry cough
- chest pain that gets worse when coughing, sneezing or breathing deeply
- chest pressure
- dizziness
- fainting
- rapid, irregular, or pounding heartbeat
- unusual bruising or bleeding
- black and tarry stools
- red blood in stools
- bloody vomit
- vomiting material that looks like coffee grounds
- slow or difficult speech
- weakness or numbness of an arm or leg
- sudden severe headache
Dasatinib may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
What storage conditions are needed for this medicine?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
What other information should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to dasatinib.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
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