Defibrotide Side Effects
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Recently reported Defibrotide Side Effects
| Common Defibrotide Side Effects | |
|---|---|
| Blood pressure decreased | 33% |
| Acidosis | 17% |
| Ascites | 17% |
| Blood bilirubin increased | 17% |
| Bradycardia | 17% |
| Cardiac enzymes increased | 17% |
| Cardio-respiratory arrest | 17% |
Dialysis  | 17% |
| Dilatation ventricular | 17% |
| Gallbladder disorder | 17% |
| Haematemesis | 17% |
| Haemoglobin decreased | 17% |
| Haemothorax | 17% |
| Hepatic cyst | 17% |
| Hepatic mass | 17% |
| Hepatomegaly | 17% |
| Hypertension | 17% |
| Hypotension | 17% |
| Myocardial infarction | 17% |
| Nausea | 17% |
| Oxygen saturation decreased | 17% |
| Pulmonary oedema | 17% |
| Renal failure | 17% |
| Renal failure acute | 17% |
| Respiratory disorder | 17% |
| Resuscitation | 17% |
| Tachycardia | 17% |
| Tachypnoea | 17% |
| Ultrasound liver abnormal | 17% |
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Defibrotide Side Effects reported on Patientsville.com
None reported at this time.Defibrotide Side Effects reported to FDA
Defibrotide Side Effects Report #5176702-9
Physician from UNITED STATES reported Defibrotide side effect on Dec 13, 2006. Male patient, weighting 220.5 lb, was diagnosed with venoocclusive disease and was treated with Defibrotide. After drug was administered, patient experienced the following side effects: acidosis, blood bilirubin increased, blood pressure decreased, cardiac enzymes increased, cardio-respiratory arrest, dilatation ventricular, haemoglobin decreased, haemothorax. Defibrotide dosage: 1000MG Q6HRS IV. During the same period patient was treated with ACETYLCYSTEINE, ACYCLOVIR, CASPOFUNGIN, FILGRASTIM, LEVOFLOXACIN, MEROPEREM, METHYLPREDNISOLONE, TACROLIMUS. Patient recovered.
Defibrotide Side Effects Report #5771962-5
Defibrotide side effect was reported by a Health Professional from UNITED STATES on June 12, 2008. Female patient, 26 years of age, weighting 154.3 lb, was diagnosed with venoocclusive liver disease and was treated with Defibrotide. After drug was administered, patient experienced the following side effects: dialysis
, renal failure acute. Defibrotide dosage: 460 MG EVERY 6 HOURS IV DRIP. During the same period patient was treated with GANCICLOVIR, LACTULOSE, METHADONE, MICAFUNGIN, MYCOPHENOLATE MOFETIL, ZOSYN, SEROQUEL. Patient died on 06/09/2008.Defibrotide Side Effects Report #4739433-2
Health Professional from UNITED STATES reported Defibrotide side effect on Aug 08, 2005. Female patient, weighting 200.4 lb, was diagnosed with venoocclusive liver disease and was treated with Defibrotide. After drug was administered, patient experienced the following side effects: hypotension, pulmonary oedema, renal failure, tachypnoea. Defibrotide dosage: 60 MG/KG Q24HOURS INTRAVENOUS. During the same period patient was treated with PROGRAF, MYCOPHENOLATE, LACTULOSE, CASPOFUNGIN, ACYCLOVIR. Patient died on 08/03/2005.
Defibrotide Side Effects Report #4811217-6
Defibrotide side effect was reported by a Pharmacist from UNITED STATES on Oct 26, 2005. Male patient, weighting 142.6 lb, was diagnosed with venoocclusive liver disease and was treated with Defibrotide. After drug was administered, patient experienced the following side effects: ascites, gallbladder disorder, hepatic cyst, hepatic mass, hepatomegaly, ultrasound liver abnormal. Defibrotide dosage: 20 - 30 MG/KG/DAY. Patient died on 10/09/2005.
Defibrotide Side Effects Report #4834179-4
Health Professional from UNITED STATES reported Defibrotide side effect on Nov 18, 2005. Male patient, 41 years of age, weighting 264.6 lb, was diagnosed with venoocclusive disease and was treated with Defibrotide. After drug was administered, patient experienced the following side effects: hypertension, myocardial infarction, tachycardia. Defibrotide dosage: 800 MG Q 6 HRS. During the same period patient was treated with HYDROMORPHONE, BENADRYL, DIPHENHYDRAMINE, TRIAMCINOLONE, DRY SKIN BATH OIL, DILAUDID, INSULIN, CHLORHEXIDINE. Patient recovered.
Defibrotide Side Effects Report #4955795-5
Defibrotide side effect was reported by a Physician from UNITED STATES on Mar 27, 2006. Female patient, weighting 35.27 lb, was diagnosed with bone marrow transplant
, venoocclusive liver disease and was treated with Defibrotide. After drug was administered, patient experienced the following side effects: blood pressure decreased, bradycardia, haematemesis, nausea , oxygen saturation decreased, respiratory disorder, resuscitation. Defibrotide dosage: 40MG/KG IV/Q6HRS Q6HRS IV. Patient recovered.