Deplin Side Effects summary

Total Deplin reports: 1. View

Deplin FDA safety alerts: No.

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Recently reported Deplin Side Effects

Constant throbbing in head. Feel pressure in my he...

My husband had been on Cymbalta and Lithium for se...

Pounding, splitting, migraine-like, headache in th...

Made my other medications work great, was able to ...

I have went through so much, and am going through ...

On 11/7/08 I was given a pill deplin by a pa at do...


Common Deplin Side Effects
Crying 100%
Depressed mood 100%

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Have you experienced Deplin side effects?
Yes, Severe35%
Yes, Mild27%
Yes, Minor10%
No29%


Deplin Comments and Questions

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Comments to date: 2. Page 1 of 1.

Belinda   USA 

10:59pm on Saturday, June 6th, 2009

Delpin is not for every one you need to have your blood check to see if you need it or not there is ... read more »

DIANE   PENNSYLVANIA 

9:11pm on Thursday, June 4th, 2009

SOUNDS LIKE THE DEPLIN CAUSED SOMETHING LIKE A SERATONIN STORM. I ALSO HAVE HAD REACTIONS TO DEPLIN ... read more »


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Deplin Side Effects reported on Patientsville.com


Deplin Side Effects Report #SELF2346 -2008-11-07
DEPLIN side effect was reported on 2008-11-07
Patient reported the following DEPLIN side effects:"On 11/7/08 I was given a pill deplin by a pa at doc office. Within hours of taking it I began to shake uncontrollably, head tremor, burning inside and out, neuropathy, hard pounding racing heart, stomach cramps, unintelligible thinking, diarhea, muscle twitches, and complete insomnia. I developed an unexplained heightened state with no cause. Intense chills in body, especially in legs, tinging, head tremor. Convulsive jerks, and so much has happened to describe. It has been intolerable. In the last 95 days I only slept 1-4 hours using benadryl and 30-40 nights have not slept at all. I was not treated properly, first hospital never heard of drug, next a doctor said I was nervous and covered my mouth. I also lost the ability to laugh, smile, watch tv, or read within that same night. I have children and a family that needs me back. Just days before taking this pill I was fine, happily planning a remodel of my kitchen. You can confirm all I am telling you with my family and friends. I lost 14 pounds in first month and only weight 92 pounds. Previous to this I took 12.5 mgs of diazepam for some panic attacks, had taken 6mgs for 14 plus years. NEVER had anything like this at all. The reaction changed me, physically and mentally. I have NO history of any mental illness. I am not mentally ill. I have no ins. and ended up a few days ago seeing a phyciatrist who put me on 60mgs of valium, for some very odd reason it only slightly helps the awful heightened state with no external cause. I am in serious trouble! I NEED YOUR HELP ASAP PLEASE! I do not have insurance and wonder if I was someone important I may have gotten help. MY life is in danger. I am still having smptoms at this high dose of valium, it is not nerves. I will not survive this without help. Please take me seriously, PlEASE HELP ME! THANK YOU, JENNIFER CONNELLEY "Read more


Deplin Side Effects Report #SELF2427 -2008-11-07
DEPLIN side effect was reported on 2008-11-07
Patient reported the following DEPLIN side effects:"I have went through so much, and am going through quite an ordeal. It may be a very complicated case, but I believe you if anyone might be able to help me, and have the resources to those who could. I am hoping you will get this in time to help me soon.I am willing to do whatever it takes to be helped and get my life back.If you had met me before this, you wouldn’t believe I was the same person. *Here is what happened: On 11/6/08 I was a 41 year old functioning woman, who took care of her family, shopped, cooked, laughed, was an avid reader, had close relations with my children. Then it all changed overnight. I was given a pill (Deplin) off label by a pa that I had a very severe reaction to. A 41 year old stable woman does not take a pill, have a reaction, and turn “mental” overnight. I was not treated, have been and am going through hell. I want my life back! Please help me get my life back.On 11/7/08 I was given a pill deplin by a pa at doc office. Within hours of taking it I began to shake uncontrollably, head tremor, burning inside and out, severe burning hands and feet, neuropathy, hard pounding racing heart, stomach cramps, unintelligible thinking, diarhea, muscle twitches, and complete insomnia. I developed an unexplained heightened state with no cause. Intense chills in body, especially in legs, tingling hands and feet, head tremor. Convulsive jerks, odd intrusive thoughts, and much more to describe. It has been intolerable. In the last 100 plus days I only slept 1-4 hours using benadryl and 30-40 nights have not slept at all. I was not treated properly, first hospital never heard of drug, next a doctor said I was nervous and covered my mouth due to the uncontrollable shaking, he had no interest in my story or what happened to me.I also lost the ability to laugh, smile, watch tv, or read, have normal conversations and relations with my children that same night 11/7/08. I have children and a family that needs me back. Just days before taking this pill I was fine, happily planning a remodel of my kitchen. You can confirm all I am telling you with my family and friends. I did have occasional anxiety attacks, which passed easily, and nothing what so ever like this. Od of reg folic acid can cause central nervous system damage. Deplin is different and goes straight to the brain. I cant explain why this happened to me, but it did, and is the 100 percent truth. I Really need your help asap. I lost 15 pounds in first month and only weigh 92 pounds. Previous to this I took 12.5 mgs of diazepam for some anxiety attacks, had taken 6mgs for 14 plus years. I have NO history of any mental illness, this can be confirmed. I have no ins. and ended up seeing a psychiatrist on 2/6/09 who put me on 60mgs of valium to try to help me, but for some very odd reason it only helps the awful heightened state with no external cause, to an extent less expected by the doctor. I still am not sleeping much as he expected this dose would help either. I am so afraid of being at this high dose, but have no choice. I have no compulsions, no bipolar symptoms, or anything that anyone else thinks matches mental illness heard of. As I said, I have no history of mental illness.If it were nerves, the symptoms would stop with the high dose of valium? I get chills constantly, but also sweat at night, and developed joint/connective tissue pain, and popping in joints. My heart races more at night when trying to sleep and upon awakening, but at other times as well, as well as continued internal shaking, tingling in hands and feet. I am in serious trouble! I am afraid for my life and future! I do not have insurance. I am still having symptoms at this high dose of valium, it is not nerves, nor does it feel like any anxiety. Please take me seriously! I need my life to matter to someone. Please Help Me! Some symptoms had subsided some, such as the neuropathy over the past few weeks, and the jerking while half asleep had subsided, but I still have many symptoms and a long way to go. It has been suggested that some of my symptoms match neurological or CNS damage. I don’t know who to believe, or listen to, I just know what happened to me, and that I need help. Maybe it cant be explained, but it happened exactly as I have explained. The Doctor I was seeing is family practice and says she does not know what else to check for. Basic thyroid okay, basic liver okay, blood count okay. I also have rashes/hives that come and go, and have lessened somewhat recently.How is it possible that 60mgs only partially effects me?What else could be happening metabolically or otherwise that this reaction changed in me, physically and mentally?Everything I am telling you is the 100 % honest truth of what occurred and is. I may be asking a lot, but I need your help, and anyone you might confer with.I am no longer going to the clinic where the pa gave me the sample Deplin. I have info on it for your review. Something terrible happened to me that destroyed who I am and my life. If there is anything you can think of, any idea of what might have occurred, what to check for, and if it can be fixed. I would appreciate your help. I have NO history of drug use/abuse, I do not drink at all, and have never abused my prescription. There is something being missed, and I don’t know where else to turn.If you have any resources available to help me, please contact me. I need someone to listen to what happened and help me. I am so scared being at such a high dose of Diazepam (valium) but do not have any other choice right now. I am sorry to bother you, this is out of character for me before now, but I am at the end of what I can take anymore of this and afraid for my future. My husband needs to be out looking for work, and is no longer able to take care of me, this has made me disabled in many ways, and I have no where to turn for treatment and help other than the psychiatrist who is trying to help me. However, he doesn’t have much interest in what happened to me with the drug reaction to deplin, or determining what might be causing my symptoms, other than nerves, which just does not compute.I simply cant stand to go back into that heightened state without the high dose of diazepam, but do not want to continue taking so much either, it is dangerously addicting, but no other choice for now. I pray you will hear my pleas today, and help me. I am asking with all my heart and prayers that you will help me asap.Thank you so very much for your immediate consideration, Sincerely,Jennifer Connelley mjstac@comcast.net "Read more


Deplin Side Effects Report #SELF2789 -2008-04-01
DEPLIN side effect was reported on 2008-04-01
Patient reported the following DEPLIN side effects:"Made my other medications work great, was able to cut my Depakote and Lithium IN HALF!"Read more


Deplin Side Effects Report #SELF3324 -2008-06-12
DEPLIN side effect was reported on 2008-06-12
Patient reported the following DEPLIN side effects:"Pounding, splitting, migraine-like, headache in the right temple area."Read more


Deplin Side Effects Report #SELF3529 -2009-07-12
DEPLIN side effect was reported on 2009-07-12
Patient reported the following DEPLIN side effects:"My husband had been on Cymbalta and Lithium for several years and his folic acid has been low. So the doctor gave him some samples of Deplin to take for several weeks. He has become less energetic than previously, less able to sleep, he got bronchial pneunomia (not sure it was in any way related), but he has been very slow to improve with his breathing. The main concern for me has been his personality/attitude change. He has been very much not himself, (actually he has seemed back to his behavior before being prescribed Cymbalta and Lithium and it is frightening me) short temper, angry, sarcastic. I have felt this all came about in the past couple of weeks and the only thing I can relate it to is the Deplin. After reading the side effects of others, it all seems to fit. He has had a racing heart, hot or cold easily, severe vomiting and some diarrhea. We ended up at the E.R. last night because of the vomiting and he is no longer taking the Deplin. I just wonder how long it\'s going to take for the side effects to go away. I am hopeful that it will be quick since he was not on it for long."Read more



Deplin Side Effects reported to FDA

Quick-Add Your Side Effect:

Deplin Side Effects Report #5321260-9
Consumer or non-health professional from UNITED STATES reported Deplin side effect on May 07, 2007. Female patient, 47 years of age, weighting 155.0 lb, was diagnosed with depression What is  depression and was treated with Deplin. After drug was administered, patient experienced the following side effects: crying, depressed mood. Deplin dosage: 7.5 MG ONE PER DAY PO. Patient recovered.





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