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Desflurane Side Effects submitted to FDA

Total Desflurane reports: 3.
Desflurane FDA safety alerts: No.
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FDA Reported Desflurane Side Effects: liver injury, hepatitis cholestatic, failure to thrive,
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Desflurane Side Effects Report #5622883-X
Physician from UNITED STATES reported DESFLURANE problem on Feb 07, 2008. Female patient, 53 years of age, was treated with DESFLURANE. After drug was administered, patient experienced the following problems/side effects: cholestasis, hepatic failure, hepatic fibrosis, hepatotoxicity, international normalised ratio increased, liver injury. DESFLURANE dosage: unknown. During the same period patient was treated with MELLARIL, NEXIUM, PRILOSEC, PROTONIX, BUSPAR, FERROUS SULPHATE. Patient recovered.



Desflurane Side Effects Report #5732823-0
DESFLURANE problem was reported by a Physician from UNITED STATES on May 07, 2008. Male patient, 54 years of age, weighting 170.0 lb, was treated with DESFLURANE. After drug was administered, patient experienced the following problems/side effects: blood ph decreased, bradycardia, cardiac arrest, cardiomyopathy, hypertension, pco2 increased. DESFLURANE dosage: unknown. During the same period patient was treated with LABETALOL, LIDOCAINE, BUPIVACAINE, ROCURONIUM BROMIDE, FENTANYL, MIDAZOLAM, REMIFENTANYL. Patient recovered.



Desflurane Side Effects Report #5363246-4
Physician from UNITED STATES reported DESFLURANE problem on June 18, 2007. Female patient, 50 years of age, was treated with DESFLURANE. After drug was administered, patient experienced the following problems/side effects: failure to thrive, hepatitis cholestatic, liver injury. DESFLURANE dosage: unknown. During the same period patient was treated with LEVOFLOXACIN, INSULIN, TYLENOL, MORPHINE, ZOFRAN, SINGULAIR, ALBUTEROL, ATROVENT. Patient recovered.




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