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Dexeryl Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Infusion Site Extravasation, Medical Device Complication, Peripheral Motor Neuropathy, Peripheral Sensory Neuropathy (7903150-8)
on Nov 04, 2011 Male from FRANCE , 68 years of age, weighting 119.0 lb, was diagnosed with
  • palmar-plantar erythrodysaesthesia syndrome
  • abdominal pain
and was treated with Dexeryl [glycerol,paraffin, Liquid,white Soft Paraffin]. Directly after, patient experienced the unwanted or unexpected Dexeryl side effects: infusion site extravasation, medical device complication, peripheral motor neuropathy, peripheral sensory neuropathy. Dexeryl [glycerol,paraffin, Liquid,white Soft Paraffin] dosage: 2 Applications Per Day.
Associated medications used:
  • Tramadol Hcl (200 Mg (daily Dose), Prn, Oral)
  • Nexium (40 Mg (daily Dose), ,)
  • Resource Energy Plus Nos (2 Packs)
  • Lasix (20 Mg (daily Dose), ,)
  • Sorafenib (raf Kinase Inhibitor) (400 Mg, Bid)
  • Vitalipide (10 Ml (daily Dose), ,)
  • Sorafenib (raf Kinase Inhibitor) (150 Mg, Qd)
  • Sorafenib (raf Kinase Inhibitor) (150 Mg, Qd)
Patient was hospitalized.

Depression (7769231-7)
Patient was taking Dexeryl. Patient felt the following Dexeryl side effects: depression on Sep 12, 2011 from FRANCE Additional patient health information: Female , weighting 140.0 lb, . Dexeryl dosage: Total Daily Dose 3 Appl.
Multiple prescriptions taken:
  • Erythromycin (Total Daily Dose: 3 Appl)
  • Ro 5190591 (itmn-191) (Last Dose Prior To Sae 23 June 2011 Frequency: Daily)
  • Erythropoietin Beta (30000 Ui/week)
  • Lercanidipine
  • Bromazepam (3 Mg As Needed)
  • Acetaminophen
  • Peginterferon Alfa-2a (Dose Form: Vials. Last Dose Prior To Sae 21 June 2011. Frequency: Weekly)
  • Ritonavir (Last Dose Prior To Sae 23 June 2011 Frequency :daily)
Patient was hospitalized.

Ascites (7631319-9)
Adverse event was reported on Jul 18, 2011 by a Male taking Dexeryl [glycerol,paraffin, Liquid,white Soft Paraffin] (Dosage: 3 Appl/day) was diagnosed with
  • dry skin
  • prophylaxis
  • odynophagia
and. Location: FRANCE , 63 years of age, weighting 187.4 lb, After Dexeryl was administered, patient encountered several Dexeryl side effects: ascites.
Multiple concurrent drugs taken:
  • Tiorfan (100mg As Needed)
  • Fluconazole (Unk)
  • Erlotinib Hydrochloride (150 Mg, Qd)
  • Erlotinib Hydrochloride (150 Mg, Qd)
  • Erlotinib Hydrochloride (150 Mg, Qd)
  • Lantus (20 U, Unk)
  • Stomatologicals, Mouth Preparations (Unk Unk, Prn)
  • Acetaminophen (3g Prn)
Patient was hospitalized.

Skin Toxicity (7582988-3)
on Jun 22, 2011 Female from FRANCE , 56 years of age, weighting 143.3 lb, was diagnosed with
  • prurigo
  • insomnia
  • hiv infection
  • paraesthesia
and was treated with Dexeryl. Directly after, patient experienced the unwanted or unexpected Dexeryl side effects: skin toxicity. Dexeryl dosage: N/A.
Associated medications used:
  • Imovane
  • Ritonavir
  • Acetaminophen
  • Tmc114
  • Raltegravir
  • Cotrim
  • Atarax
Patient was hospitalized.


Activated Partial Thromboplastin Time Prolonged, Coagulation Factor V Level Decreased, Prothrombin Time Shortened (7527916-1)
on May 20, 2011 Female from FRANCE , 81 years of age, was treated with Dexeryl (glycerol, Paraffin, Liquid, White Soft Paraffin) Cream. Patient felt the following Dexeryl side effects: activated partial thromboplastin time prolonged, coagulation factor v level decreased, prothrombin time shortened. Dexeryl (glycerol, Paraffin, Liquid, White Soft Paraffin) Cream dosage: N/A.
Multiple prescriptions taken:
  • Mupiderm (mupirocin) Ointment, Cream, 2%
  • Nitroglycerin Spray
  • Angiomax (10.5 Ml, Bolus, Intravenous; 24.5 Ml, Intravenous)
  • Angiomax (10.5 Ml, Bolus, Intravenous; 24.5 Ml, Intravenous)
  • Ginkor Fort (ginkgo Biloba, Hepatminol Hydrochloride, Troxerutin) Caps
  • Morphine
  • Fixical (calcium Carbonate)
  • Aspegic (acetylsalicylate Lysine, Aminoacetic Acid)
Patient was hospitalized.

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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