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Diamicron Side Effects

Common Diamicron Side Effects


The most commonly reported Diamicron side effects (click to view or check a box to report):

Pain (7)
Malaise (6)
Asthenia (6)
Hyperkalaemia (5)
Fall (5)
Diarrhoea (4)
Dyspnoea (4)
Dehydration (4)
Pyrexia (4)
Rash (4)
Hypokalaemia (3)
Vomiting (3)
Hypoglycaemia (3)
Alopecia (3)
Upper Respiratory Tract Infection (3)
Renal Failure Acute (3)
Myalgia (3)
Oedema Peripheral (3)
Pneumonia (3)
Thrombocytopenia (3)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

Diamicron Side Effects Reported to FDA

The following Diamicron reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.


The appearance of Diamicron on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.
Wound, Joint Injury
This is a report of a 65-year-old female patient (weight: NA) from BR, suffering from the following symptoms/conditions: diabetes mellitus,osteoarthritis, who was treated with Diamicron (dosage: Unk, start time: NS), combined with:
  • Oscal /00514701/ (Unk)
  • Methotrexate (Unk Unk, Unk)
  • Prelone /00016201/ (Unk)
  • Enbrel (50 Mg, 1x/week)
and developed a serious reaction and side effect(s). The consumer presented with:
  • Wound
  • Joint Injury
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Diamicron treatment in female patients, resulting in wound side effect.

Joint Swelling, Pain, Gouty Arthritis
This report suggests a potential Diamicron Joint Swelling, Pain, Gouty Arthritis side effect(s) that can have serious consequences. A 60-year-old male patient (weight: NA) from MALAYSIA was diagnosed with the following symptoms/conditions: NA and used Diamicron (dosage: NA) starting Mar 11, 2011. Soon after starting Diamicron the patient began experiencing various side effects, including:
  • Joint Swelling
  • Pain
  • Gouty Arthritis
Drugs used concurrently:
  • Glucophage
Although Diamicron demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as joint swelling, may still occur.

Bladder Cancer
This Bladder Cancer problem was reported by a health professional from FRANCE. A 56-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: type 2 diabetes mellitus,congestive cardiomyopathy. On Dec 01, 2009 this consumer started treatment with Diamicron (dosage: NA). The following drugs were being taken at the same time:
  • Bisoprolol Fumarate
  • Aspirin
  • Prazosin Hcl
  • Actos
  • Minirin
  • Fenofibrate
  • Kayexalate
  • Januvia
When commencing Diamicron, the patient experienced the following unwanted symptoms/side effects:
  • Bladder Cancer
The patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as bladder cancer, may become evident only after a product is in use by the general population.

Renal Failure, Malnutrition, Diarrhoea
This is a report of a 82-year-old male patient (weight: NA) from SPAIN. The patient developed the following symptoms/conditions: NA and was treated with Diamicron (dosage: NA) starting Jun 01, 2011. Concurrently used drugs:
  • Tramadol Hydrochloride
  • Urolosin
  • Galvus
  • Aspirin
  • Stalevo 100 (1 Df Daily, 50/12.5/200 Mg, Oral)
  • Neurontin
  • Valdoxan
  • Noctamid
Soon after that, the consumer experienced the following side effects:
  • Renal Failure
  • Malnutrition
  • Diarrhoea
This opens a possibility that Diamicron treatment could cause the above reactions, including renal failure, and some male subjects may be more susceptible.


Pruritus, Erythema
A 70-year-old female patient (weight: NA) from SPAIN with the following symptoms/conditions: diabetes mellitus started Diamicron treatment (dosage: 80 Unk, Unk) on Apr 27, 2009. Soon after starting Diamicron treatment, the subject experienced various side effects, including:
  • Pruritus
  • Erythema
Concurrently used drugs:
  • Aranesp (150 Mug, Qmo)
  • Enalapril Maleate (5 Unk, Qd)
  • Aranesp (150 Mug, Qmo)
  • Metformin Hcl (850 Unk, Unk)
  • Ferbisol (100 Mg, Qd)
This finding indicates that some female patients could be more vulnerable to Diamicron.

Alopecia, Breast Mass
A 73-year-old female patient from BRAZIL (weight: NA) experienced symptoms, such as: diabetes mellitus,blood cholesterol increased,depression,hypertension,gastritis and was treated with Diamicron(dosage: NA). The treatment was initiated on Jan 01, 2009. After that a consumer reported the following side effect(s):
  • Alopecia
  • Breast Mass
Concurrently used drugs, which potentially could have contributed to side effect(s) or affected Diamicron efficacy:
  • Vytorin (10/20 Mg)
  • Procimax
  • Irbesartan
  • Nexium
  • Galvus Met (50/850 Mg)
The patient was hospitalized.

Platelet Count Decreased, Vomiting, Dehydration, Diarrhoea
In this report, Diamicron was administered for the following condition: NA.A 82-year-old female consumer from BRAZIL (weight: NA) started Diamicron treatment (dosage: 60 Mg, 1x/day) on Apr 19, 2012.Sometime after starting the treatment, the patient complained of the following side effect(s):
  • Platelet Count Decreased
  • Vomiting
  • Dehydration
  • Diarrhoea
A possible interaction with other drugs could have contributed to this reaction:
  • Sutent (50 Mg, 1x/day)
  • Metformin Hydrochloride (1000 Mg, 1x/day)
The patient was hospitalized.Establishing a causal relationship between a specific drug and consumer's side effects is complex, but it is possible that in this report Diamicron treatment could be related to the listed above side effect(s).

Posterior Reversible Encephalopathy Syndrome
This is a report of the following Diamicron side effect(s):
  • Posterior Reversible Encephalopathy Syndrome
A 56-year-old female patient from FRANCE (weight: NA) presented with the following condition: NA and received a treatment with Diamicron (dosage: 2 Df, Qd) starting: Mar 06, 2012.The following concurrently used drugs could have generated interactions:
  • Prednisolone (Unk)
  • Nexium (Unk)
  • Lyrica (50 Mg)
  • Imovane (1 Df, Qd)
  • Oxycontin (120 Mg, Bid)
  • Oxynorm (20 Mg, Prn)
  • Ciprofloxacin Hydrochloride (Unk)
  • Lexomil
The patient was hospitalized.This report suggests that a Diamicron treatment could be associated with the listed above side effect(s).

Angioedema
This Diamicron report was submitted by a 63-year-old female consumer from US (weight: NA). The patient was diagnosed with: type 2 diabetes mellitus and Diamicron was administered (dosage: 07jun-26aug11,30mg?26aug11-5jul2012:60mg?5jul2012-ong:120mg) starting: Dec 01, 2011. The consumer developed a set of symptoms:
  • Angioedema
Other drugs used simultaneously: NA.Those unexpected symptoms could be linked to a Diamicron treatment, however establishing a potential drug-safety problem requires a more detailed clinical analysis.

Myalgia, Fluid Retention, Back Pain, Swelling, Polymyositis, Gait Disturbance
This is a report of a possible correlation between Diamicron use and the following symptoms/side effect(s):
  • Myalgia
  • Fluid Retention
  • Back Pain
  • Swelling
  • Polymyositis
  • Gait Disturbance
which could contribute to an assessment of Diamicron risk profile.A male consumer from BRAZIL (weight: NA) was suffering from diabetes mellitus,blood pressure,prostatectomy and was treated with Diamicron (dosage: 30 Mg, Unk) starting Feb 28, 2012.Other concurrent medications:
  • Carvedilol (12.5 Mg, Unk)
  • Doxazosin Mesylate (1 Df, Qd)
  • Naprix (10 Mg, Unk)
  • Cefaclor
  • Amiodarone Hydrochloride (200 Mg, Unk)
The patient was hospitalized.

Hyperkalaemia, Angioedema, Dysarthria, Dyspnoea, Salivary Hypersecretion
A 75-year-old male patient from FRANCE (weight: NA) presented with the following symptoms: NA and after a treatment with Diamicron (gliclazide) (dosage: NA) experienced the following side effect(s):
  • Hyperkalaemia
  • Angioedema
  • Dysarthria
  • Dyspnoea
  • Salivary Hypersecretion
The treatment was started on Nov 28, 2011. Diamicron (gliclazide) was used in combination with the following drugs:
  • Calcitriol
  • Aceon (2 Mg, Qd, Oral)
  • Lasilix (furosemide)
  • Allopurinol
  • Lercanidipine
  • Crestor
  • Rocaltrol
  • Sodium Bicarbonate
The patient was hospitalized.This report could alert potential Diamicron (gliclazide) consumers.

Ischaemic Cerebral Infarction
In this report, a 77-year-old male patient from SPAIN (weight: NA) was affected by a possible Diamicron side effect.The patient was diagnosed with NA. After a treatment with Diamicron (dosage: 30 Mg, Qd, start date: Jan 12, 2012), the patient experienced the following side effect(s):
  • Ischaemic Cerebral Infarction
The following simultaneously used drugs could have led to this reaction:
  • Nitroglycerin (15 Mg, Qd)
  • Ciprofloxacin (500 Mg, Bid)
  • Aspirin (150 Mg, Qd)
  • Finasteride (5 Mg, Qd)
  • Panitumumab (4.8 Mg/kg, Q2wk)
  • Simvastatin (20 Mg, Qd)
  • Paclitaxel (80 Mg/m2, Qwk)
The patient was hospitalized.The findings here stress that side effects should be taken into consideration when evaluating a Diamicron treatment.

Cardiovascular Disorder, Hyperglycaemia
This is a report of a 49-year-old male patient from VENEZUELA (weight: NA), who used Diamicron (dosage: Unk) for a treatment of NA. After starting a treatment on NS, the patient experienced the following side effect(s):
  • Cardiovascular Disorder
  • Hyperglycaemia
The following drugs could possibly have interacted with the Diamicron treatment
  • Humalog (Unk, Tid)
  • Humalog (Unk, Tid)
  • Plavix (Unk)
  • Hyzaar (Unk)
  • Coraspirina (Unk)
  • Enalapril Maleate (Unk)
Taken together, these observations suggest that a Diamicron treatment could be related to side effect(s), such as Cardiovascular Disorder, Hyperglycaemia.

Bronchopneumonia, Thrombocytopenia, Pyrexia
This bronchopneumonia side effect was reported by a physician from FRANCE. A male patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Diamicron (dosage: 100 Milligram), which was started on Apr 03, 2012. Concurrently used drugs:
  • Lexomil (6 Milligram)
  • Losartan/hydrochlorotiazide (100 Milligram)
  • Amiodarone Hcl (200 Milligram)
  • Ursodiol (250 Milligram)
  • Loscon (100 Milligram)
  • Revlimid (10 Milligram)
  • Neorecormon
  • Metformin Hcl (850 Milligram)
When starting to take Diamicron the consumer reported the following symptoms:
  • Bronchopneumonia
  • Thrombocytopenia
  • Pyrexia
The patient was hospitalized. These side effects may potentially be related to Diamicron.

Lung Infection, Thrombocytopenia
This is a Diamicron side effect report of a 64-year-old female patient (weight:NA) from GREECE, suffering from the following symptoms/conditions: hyperglycaemia, who was treated with Diamicron (dosage:Unk, start time: Sep 26, 2011), combined with:
  • Fenistil (8 Mg, Unk)
  • Arixtra (2.5 Mg, Bid)
  • Zofran (8 Mg, Unk)
  • Tenormin (50 Mg, Bid)
  • Digoxin (0.5 Mg, Unk)
  • Eloxatin (130 Mg/m2, Q3wk)
  • Panitumumab (9 Mg/kg, Q3wk)
  • Zantac (50 Mg, Unk)
, and developed a serious reaction and a lung infection side effect. The patient presented with:
  • Lung Infection
  • Thrombocytopenia
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Diamicron treatment in female patients suffering from hyperglycaemia, resulting in lung infection.

Bladder Transitional Cell Carcinoma Stage Ii, Cardiomyopathy
This report suggests a potential Diamicron (gliclazide) bladder transitional cell carcinoma stage ii side effect(s) that can have serious consequences. A 56-year-old male patient from FRANCE (weight:NA) was diagnosed with the following health condition(s): type 2 diabetes mellitus and used Diamicron (gliclazide) (dosage: 30 Mg, Qd, Oral) starting Jan 01, 1995. Soon after starting Diamicron (gliclazide) the patient began experiencing various side effects, including:
  • Bladder Transitional Cell Carcinoma Stage Ii
  • Cardiomyopathy
Drugs used concurrently:
  • Perindopril Erbumine (2.5 Mg)
  • Aceon (2.5 Mg,qd,oral)
  • Bisoprolol Fumarate (2.5 Mg, Qd, Oral)
  • Allopurinol (300 Mg, Qd, Oral)
  • Fenofibrate (200 Mg, Qd, Oral)
  • Januvia (100 Mg, Qd, Oral)
  • Kayexalate (1 Unit Every 2 Weeks, Oral)
  • Aspirin (75 Mg, Qd, Oral)
The patient was hospitalized. Although Diamicron (gliclazide) demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as bladder transitional cell carcinoma stage ii, may still occur.

Flatulence, Diarrhoea, Night Sweats, Diverticulum, Insomnia
This flatulence problem was reported by a physician from AUSTRALIA. A female patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Nov 25, 2008 a consumer started treatment with Diamicron (dosage: NA). The following drugs/medications were being taken at the same time:
  • Metformin Hcl
  • Nexium
  • Panadol Osteo
  • Perindopril Erbumine
  • Felodur
  • Cardiprin
  • Zocor
When commencing Diamicron, the patient experienced the following unwanted symptoms /side effects:
  • Flatulence
  • Diarrhoea
  • Night Sweats
  • Diverticulum
  • Insomnia
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as flatulence, may become evident only after a product is in use by the general population.

Pyrexia, Agranulocytosis
This is a Diamicron side effect report of a 63-year-old male patient (weight: NA) from FRANCE. The patient developed the following symptoms/conditions: NA and was treated with Diamicron (dosage: Form: Tab Lp) starting Feb 07, 2012. Concurrently used drugs:
  • Lantus
  • Aspirin
  • Crestor
  • Novorapid
Soon after that, the consumer experienced the following of symptoms:
  • Pyrexia
  • Agranulocytosis
The patient was hospitalized. This opens a possibility that Diamicron could cause pyrexia and that some male patients may be more susceptible.

Myopia, Astigmatism, Eye Irritation, Glaucoma, Ulcer
A 57-year-old female patient (weight: NA) from BRAZIL with the following symptoms: blood pressure increased,rheumatoid arthritis,myopia,hypothyroidism started Diamicron treatment (dosage: Unk) on NS. Soon after starting Diamicron treatment, the consumer experienced several side effects, including:
  • Myopia
  • Astigmatism
  • Eye Irritation
  • Glaucoma
  • Ulcer
. Concurrently used drugs:
  • Meticorten (Unk)
  • Xalatan (1.5 Ug (on Drop In The Left Eye) Once A Day)
  • Levothyroxine Sodium (Unk)
This finding indicates that some patients can be more vulnerable to developing Diamicron side effects, such as myopia.

Chest Pain, Hypertension, Memory Impairment, Coronary Artery Occlusion
This chest pain side effect was reported by a consumer or non-health professional from BRAZIL. A 78-year-old female patient (weight:NA) experienced the following symptoms/conditions: diabetes mellitus,osteoporosis,hypothyroidism,hypertension,gastrooesophageal reflux disease.The patient was prescribed Diamicron (dosage: NA), which was started on Jan 01, 2012. Concurrently used drugs:
  • Calcium Carbonate
  • Levothyroxine Sodium
  • Atacand
  • Nexium
.When starting to take Diamicron the consumer reported symptoms, such as:
  • Chest Pain
  • Hypertension
  • Memory Impairment
  • Coronary Artery Occlusion
These side effects may potentially be related to Diamicron.

Pyrexia, Agranulocytosis
This is a report of a 63-year-old male patient (weight: NA) from FRANCE, suffering from the following symptoms/conditions: NA, who was treated with Diamicron Lm (dosage: NA, start time: Feb 07, 2012), combined with:
  • Aspirin
  • Lantus
  • Crestor
  • Novorapid
and developed a serious reaction and side effect(s). The consumer presented with:
  • Pyrexia
  • Agranulocytosis
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Diamicron Lm treatment in male patients, resulting in pyrexia side effect. The patient was hospitalized.

Loss Of Consciousness, Metabolic Acidosis, Haematuria, Hypoglycaemic Coma, Decreased Appetite, Renal Failure Acute, Malaise
This report suggests a potential Diamicron Loss Of Consciousness, Metabolic Acidosis, Haematuria, Hypoglycaemic Coma, Decreased Appetite, Renal Failure Acute, Malaise side effect(s) that can have serious consequences. A 74-year-old male patient (weight: NA) from SWITZERLAND was diagnosed with the following symptoms/conditions: type 2 diabetes mellitus and used Diamicron (dosage: 60 Mg, Daily) starting Dec 01, 2011. Soon after starting Diamicron the patient began experiencing various side effects, including:
  • Loss Of Consciousness
  • Metabolic Acidosis
  • Haematuria
  • Hypoglycaemic Coma
  • Decreased Appetite
  • Renal Failure Acute
  • Malaise
Drugs used concurrently:
  • Starlix (60 Mg, Daily)
  • Amoxicillin And Clavulanate Potassium (1250 Mg, Unk)
  • Tramadol Hydrochloride (50 Mg, Unk)
  • Voltaren (1 Df, Once/single)
  • Irbesartan + Hydrochlorothiazide (150 Mg, Daily (concentration: 150/12.5))
  • Metformin Hcl (3 Mg, Daily)
The patient was hospitalized. Although Diamicron demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as loss of consciousness, may still occur.

Arthropathy
This Arthropathy problem was reported by a consumer or non-health professional from BRAZIL. A 52-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On Jul 22, 2009 this consumer started treatment with Diamicron (dosage: Unk). The following drugs were being taken at the same time:
  • Propranolol (Unk)
  • Enbrel (50 Mg, Once Weekly)
  • Metformin Hcl (Unk)
  • Hydrochlorothiazide (Unk)
When commencing Diamicron, the patient experienced the following unwanted symptoms/side effects:
  • Arthropathy
Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as arthropathy, may become evident only after a product is in use by the general population.

Neutrophil Count Increased, Toxic Skin Eruption, Rash, Eyelid Oedema, Oedema Peripheral, Lip Oedema, Rash Maculo-papular, Conjunctivitis, White Blood Cell Count Increased
This is a report of a 81-year-old male patient (weight: NA) from FRANCE. The patient developed the following symptoms/conditions: NA and was treated with Diamicron (dosage: 30 Mg) starting Apr 01, 2011. Concurrently used drugs:
  • Tegretol (2 Df, Daily)
  • Previscan (20 Mg)
  • Allopurinol (100 Mg, Unk)
  • Irbesartan (300/12.5 Mg)
  • Tramadol Hcl
  • Lyrica
Soon after that, the consumer experienced the following side effects:
  • Neutrophil Count Increased
  • Toxic Skin Eruption
  • Rash
  • Eyelid Oedema
  • Oedema Peripheral
  • Lip Oedema
  • Rash Maculo-papular
  • Conjunctivitis
  • White Blood Cell Count Increased
The patient was hospitalized. This opens a possibility that Diamicron treatment could cause the above reactions, including neutrophil count increased, and some male subjects may be more susceptible.

Eczema, Hyperthermia
A 58-year-old male patient (weight: NA) from FRANCE with the following symptoms/conditions: NA started Diamicron treatment (dosage: Unk) on Nov 17, 2011. Soon after starting Diamicron treatment, the subject experienced various side effects, including:
  • Eczema
  • Hyperthermia
Concurrently used drugs:
  • Rabeprazole Sodium (Unk)
  • Clindamycin Hcl (600 Mg, 3x/day)
  • Paracetamol (Unk)
  • Temazepam (1 Df, 1x/day)
  • Gentamicin (Unk)
  • Zosyn (4 G, 3x/day)
  • Ciprofloxacin Hcl (500 Mg, 3x/day)
  • Lexomil (Unk)
The patient was hospitalized. This finding indicates that some male patients could be more vulnerable to Diamicron.

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Top 10 Diamicron Side Effects for Women

Women Side EffectsReports
Pain 4
Alopecia 3
Asthenia 3
Brain Oedema 3
Diarrhoea 3
Dizziness 3
Dysphonia 3
Fall 3
Angioedema 2
Breast Mass 2

Top 10 Diamicron Side Effects for Men

Men Side EffectsReports
Hyperkalaemia 5
Malaise 4
Pyrexia 4
Asthenia 3
Bladder Cancer 3
Dehydration 3
Gait Disturbance 3
Pain 3
Rash 3
Renal Failure Acute 3

Keep Track of Side Effects

Note Your Observations

It is really important to keep of your symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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