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Reflux (8)
Irritation In Eyes (5)
Motilium (4)
Apnoea (3)
Loss Of Consousness (3)
Apnoea And Reflux (2)
Chest Pain (2)
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Domperidone Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 158 

Dehydration, Vomiting (8311333-0)
on Apr 19, 2012 Female from IRELAND , weighting 153.7 lb, was diagnosed with
  • nausea
  • gastrooesophageal reflux disease
and was treated with Domperidone. Directly after, patient experienced the unwanted or unexpected Domperidone side effects: dehydration, vomiting. Domperidone dosage: 90mg Per Day.
Associated medications used:
  • Omeprazole (20mg Per Day)
  • Neulasta (6mcg Per Day)
  • Docetaxel (130mg Cyclic)
  • Herceptin (441mg Cyclic)
  • Cyclizine (150mg As Required)
  • Loperamide (16mg As Required)
  • Lapatinib (1000mg Per Day)
  • Carboplatin (720mg Cyclic)
Patient was hospitalized.

Fatigue, Dyspnoea, Chest Discomfort (8308301-1)
Patient was taking Domperidone. Patient felt the following Domperidone side effects: fatigue, dyspnoea, chest discomfort on Apr 12, 2012 from UNITED KINGDOM Additional patient health information: Female , 48 years of age, weighting 154.3 lb, . Domperidone dosage: 20 Mg, Unk.
Multiple prescriptions taken:
  • Ranitidine (50 Mg, Unk)
  • Pegfilgrastim (6 Mg, Unk)
  • Dexamethasone (20 Mg, Unk)


Chest Discomfort, Fatigue, Dyspnoea (8306454-2)
Adverse event was reported on Apr 11, 2012 by a Female taking Domperidone (Dosage: 20 Mg, Four Times Daily And Then Prn) . Location: UNITED KINGDOM , 49 years of age, weighting 154.3 lb, After Domperidone was administered, patient encountered several Domperidone side effects: chest discomfort, fatigue, dyspnoea.
Multiple concurrent drugs taken:
  • Dexamethasone (20 Mg, Unk)
  • Docusate (100 Mg To 200 Mg)
  • Biotene (Qds)
  • Chlorpheniramine Maleate (10 Mg, Unk)
  • Ranitidine (50 Mg, Unk)
  • Dexamethasone (4 Mg, Bid)
  • Paclitaxel (315 Mg Every 2 Weeks For 2 Doses And 300 Mg For 2 Doses)
  • Granisetron (1 Mg, Bid)


Palpitations, Dyspnoea, Movement Disorder, Arrhythmia (8304313-2)
on Apr 23, 2012 Female from UNITED STATES , 34 years of age, weighting 140.0 lb, was diagnosed with
  • lactation disorder
and was treated with Domperidone. Directly after, patient experienced the unwanted or unexpected Domperidone side effects: palpitations, dyspnoea, movement disorder, arrhythmia. Domperidone dosage: 30mg.


Electrocardiogram Qt Prolonged, Blood Magnesium Decreased, Blood Potassium Decreased (8293741-X)
on Apr 02, 2012 Female from CANADA , 19 years of age, was treated with Domperidone (domperidone). Patient felt the following Domperidone side effects: electrocardiogram qt prolonged, blood magnesium decreased, blood potassium decreased. Domperidone (domperidone) dosage: N/A.
Multiple prescriptions taken:
  • Ciprofloxacin ((df))
  • Metronidazole


Electrolyte Imbalance, Torsade De Pointes, Electrocardiogram Qt Prolonged (8289646-0)
Patient was taking Domperidone. After Domperidone was administered, patient encountered several Domperidone side effects: electrolyte imbalance, torsade de pointes, electrocardiogram qt prolonged on Apr 02, 2012 from CANADA Additional patient health information: Female , 64 years of age, . Domperidone dosage: N/A.
Multiple concurrent drugs taken:
  • Venlafaxine Hcl
  • Amiodarone Hcl
  • Furosemide
  • Metolazone


Suicide Attempt, Delusion, Hallucination (8287910-2)
Adverse event was reported on Apr 05, 2012 by a Female taking Domperidone (Dosage: Tablet Last Dose: 1 Tab On 06may10) . Location: JAPAN , 47 years of age, weighting 112.4 lb, Directly after, patient experienced the unwanted or unexpected Domperidone side effects: suicide attempt, delusion, hallucination.
Associated medications used:
  • Zoloft (Tablet, 25mg Last Dose: 1 Tab On 06may10)
  • Zolpidem (Tablet Last Dose :1 Tab On 06may10)
  • Aripiprazole (13jan-09mar10(56d) 10mar-16mar10(7d) 3 Mg/day 17mar-20apr(35d) 1 Df = 1tab)
  • Gascon (Tablet, 40mg)
Patient was hospitalized.

Pneumonia, Atrial Fibrillation, Myocardial Infarction (8273420-5)
on Apr 05, 2012 Male from UNITED KINGDOM , 74 years of age, was treated with Domperidone. Patient felt the following Domperidone side effects: pneumonia, atrial fibrillation, myocardial infarction. Domperidone dosage: 20 Mg / 3 Days.
Multiple prescriptions taken:
  • Apo-go
  • Requip (20 Mg, Qd)
  • Stalevo 100 (200 Mg, 6qd)
  • Madopar (125 Mg, Qd)
Patient was hospitalized.

Electrolyte Imbalance, Hypomagnesaemia, Torsade De Pointes, Hypokalaemia, Electrocardiogram Qt Prolonged (8270596-0)
on Apr 02, 2012 Female from CANADA , 34 years of age, was treated with Domperidone. After Domperidone was administered, patient encountered several Domperidone side effects: electrolyte imbalance, hypomagnesaemia, torsade de pointes, hypokalaemia, electrocardiogram qt prolonged. Domperidone dosage: N/A.
Multiple concurrent drugs taken:
  • Furosemide


Neutrophil Count Decreased, Mucosal Inflammation, Nausea, Diarrhoea, Haemoglobin Decreased, Platelet Count Decreased, Bone Marrow Disorder, Blood Albumin Decreased, Malaise (8267541-0)
Patient was taking Domperidone (domperidone). Directly after, patient experienced the unwanted or unexpected Domperidone side effects: neutrophil count decreased, mucosal inflammation, nausea, diarrhoea, haemoglobin decreased, platelet count decreased, bone marrow disorder, blood albumin decreased, malaise on Mar 21, 2012 from UNITED KINGDOM Additional patient health information: Male , 57 years of age, weighting 152.1 lb, . Domperidone (domperidone) dosage: N/A.
Associated medications used:
  • Xeloda (1800 Mg, 1/3weeks)
  • Oxaliplatin (235 Mg, 1 / 3weeks, Intravenous (not Otherwise Specified))
Patient was hospitalized.

Electrocardiogram Qt Prolonged, Blood Potassium Decreased, Blood Magnesium Decreased, Torsade De Pointes (8264718-5)
Adverse event was reported on Mar 26, 2012 by a Female taking Domperidone (Dosage: N/A) . Location: ARGENTINA , 64 years of age, Patient felt the following Domperidone side effects: electrocardiogram qt prolonged, blood potassium decreased, blood magnesium decreased, torsade de pointes.
Multiple prescriptions taken:
  • Venlafaxine
  • Furosemide
  • Metolazone


Amnesia, Confusional State, Paraesthesia, Cerebrovascular Accident (8261072-X)
on May 09, 2011 Female from , weighting 180.8 lb, was treated with Domperidone (domperidone) (domperidone). After Domperidone was administered, patient encountered several Domperidone side effects: amnesia, confusional state, paraesthesia, cerebrovascular accident. Domperidone (domperidone) (domperidone) dosage: N/A.
Multiple concurrent drugs taken:
  • Topiramate (100 Milligram, 2 In 1 D, Oral Use)
  • Maxalt (rizatriptan Benzoate) (rizatriptan Benzoate)
  • Imigran (sumatriptan, Sumatriptan Succinate) (sumatriptan, Sumatriptan
  • Sumatriptan Succinate


Ejection Fraction Decreased, Hypotension, Diastolic Dysfunction, Heart Rate Decreased, Dilatation Atrial, Heart Valve Incompetence, Ventricular Hypertrophy, Pulmonary Valve Incompetence, Extrasystoles (8254858-9)
on Mar 30, 2012 Male from AUSTRALIA , weighting 152.1 lb, was treated with Domperidone. Directly after, patient experienced the unwanted or unexpected Domperidone side effects: ejection fraction decreased, hypotension, diastolic dysfunction, heart rate decreased, dilatation atrial, heart valve incompetence, ventricular hypertrophy, pulmonary valve incompetence, extrasystoles. Domperidone dosage: 10 Mg, Unk.
Associated medications used:
  • Benzhexol (1 Mg, Unk)
  • Atorvastatin (40 Mg, At Night)
  • Carbidopa + Levodopa (3.5 Df, (1.5 Df In Morning, 1 At Midday And 1 At Night))
  • Multi-vitamin
  • Metoprolol Tartrate
  • Symmetrel (100 Mg, In The Morning)
  • Olanzapine (5 Mg, At Night)
  • Omeprazole (20 Mg, At Night)


Malaise, Dyspnoea, Viral Infection, Cough (8250789-9)
Patient was taking Domperidone. Patient felt the following Domperidone side effects: malaise, dyspnoea, viral infection, cough on Mar 23, 2012 from UNITED STATES Additional patient health information: Female , weighting 18.85 lb, . Domperidone dosage: N/A.
Multiple prescriptions taken:
  • Synagis
  • Ranitidine Hcl
  • Synagis
Patient was hospitalized.

Metastases To Spine, Neoplasm Progression, Haemoglobin Decreased, Body Temperature Increased, Lower Respiratory Tract Infection, Lung Neoplasm Malignant, Platelet Count Decreased, Neutropenia (8249355-0)
Adverse event was reported on Mar 14, 2012 by a Male taking Domperidone (domperidone) (Dosage: N/A) . Location: UNITED KINGDOM , 73 years of age, After Domperidone was administered, patient encountered several Domperidone side effects: metastases to spine, neoplasm progression, haemoglobin decreased, body temperature increased, lower respiratory tract infection, lung neoplasm malignant, platelet count decreased, neutropenia.
Multiple concurrent drugs taken:
  • Dalteparin Sodium
  • Simvastatin
  • Oramorph Sr
  • Infumorph
  • Acetaminophen
  • Carboplatin (340 Mg, Intravenous)
  • Omeprazole
  • Dexamethasone
Patient was hospitalized.

Electrocardiogram Qt Prolonged, Electrolyte Imbalance (8239401-2)
on Mar 14, 2012 Female from CANADA , 19 years of age, was treated with Domperidone. Directly after, patient experienced the unwanted or unexpected Domperidone side effects: electrocardiogram qt prolonged, electrolyte imbalance. Domperidone dosage: Unk.
Associated medications used:
  • Ciprofloxacin (Unk)
  • Metronidazole (Unk)


Gastritis (8234297-7)
on Mar 19, 2012 Male from UNITED KINGDOM , weighting 169.8 lb, was treated with Domperidone. Patient felt the following Domperidone side effects: gastritis. Domperidone dosage: N/A.
Multiple prescriptions taken:
  • Epirubicin Hydrochloride
  • Capecitabine
  • Cisplatin
  • Avastin
  • Atenolol
  • Omeprazole
Patient was hospitalized.

Electrocardiogram Qt Prolonged, Hypokalaemia, Torsade De Pointes (8229835-4)
Patient was taking Domperidone. After Domperidone was administered, patient encountered several Domperidone side effects: electrocardiogram qt prolonged, hypokalaemia, torsade de pointes on Mar 09, 2012 from CANADA Additional patient health information: Female , 64 years of age, . Domperidone dosage: 10mg Tid.
Multiple concurrent drugs taken:
  • Metolazone (2.5mg Od)
  • Omeprazole (20mg Od)
  • Venlafaxine (112.5mg Od)
  • Metformin Hcl (1000mg Bid)
  • Glyburide (5mg Bid)
  • Lipitor (10mg Od)
  • Amiodarone Hydrochloride (150mg Bolus)
  • Levothyroxine Sodium (200 Microg Od)
Patient was hospitalized.

Electrocardiogram Qt Prolonged, Torsade De Pointes (8229820-2)
Adverse event was reported on Mar 09, 2012 by a Female taking Domperidone (Dosage: N/A) . Location: CANADA , 34 years of age, Directly after, patient experienced the unwanted or unexpected Domperidone side effects: electrocardiogram qt prolonged, torsade de pointes.
Associated medications used:
  • Furosemide


Blood Albumin Decreased, Dihydropyrimidine Dehydrogenase Deficiency, Malaise, Diarrhoea, Nausea, Neutrophil Count Decreased, Mucosal Inflammation, Bone Marrow Disorder (8227933-2)
on Mar 21, 2012 Male from UNITED KINGDOM , 57 years of age, weighting 152.1 lb, was treated with Domperidone. Patient felt the following Domperidone side effects: blood albumin decreased, dihydropyrimidine dehydrogenase deficiency, malaise, diarrhoea, nausea, neutrophil count decreased, mucosal inflammation, bone marrow disorder. Domperidone dosage: 40 Mg, Qd.
Multiple prescriptions taken:
  • Xeloda (1800 Mg, (1 Dose / 3 Weeks))
  • Oxaliplatin (235 Mg (one Dose / 3 Weeks))


Anaphylactic Reaction, Haemorrhage Subcutaneous (8225118-7)
on Mar 15, 2012 Female from JAPAN , weighting 127.9 lb, was diagnosed with
  • pain
and was treated with Domperidone. After Domperidone was administered, patient encountered several Domperidone side effects: anaphylactic reaction, haemorrhage subcutaneous. Domperidone dosage: 1 Per 1 Day.
Multiple concurrent drugs taken:
  • Tramadol Hydrochloride And Acetaminophen (2 Doses, 1 Per 1 Day)
  • Prochlorperazine (1 Per 1 Day)
  • Tramadol Hydrochloride And Acetaminophen (3 Df, 1 Per 1 Day)
  • Tramadol Hydrochloride And Acetaminophen (3 Df, 1 Per 1 Day)
  • Kakkon-to (1 Per 1 Day)
  • Tramadol Hydrochloride And Acetaminophen (2 Doses, 1 Per 1 Day)


Dihydropyrimidine Dehydrogenase Deficiency, Nausea, Haemoglobin Decreased, Blood Albumin Decreased, Mucosal Inflammation, Neutrophil Count Decreased, Malaise, Diarrhoea, Platelet Count Decreased (8218126-3)
Patient was taking Domperidone. Directly after, patient experienced the unwanted or unexpected Domperidone side effects: dihydropyrimidine dehydrogenase deficiency, nausea, haemoglobin decreased, blood albumin decreased, mucosal inflammation, neutrophil count decreased, malaise, diarrhoea, platelet count decreased on Mar 05, 2012 from UNITED KINGDOM Additional patient health information: Male , weighting 152.1 lb, . Domperidone dosage: N/A.
Associated medications used:
  • Xeloda (2 Vials Daily)
  • Oxaliplatin


Nausea, Malaise, Fatigue, Arthralgia, Lethargy (8216197-1)
Adverse event was reported on Mar 13, 2012 by a Female taking Domperidone (Dosage: N/A) . Location: UNITED KINGDOM , weighting 206.1 lb, Patient felt the following Domperidone side effects: nausea, malaise, fatigue, arthralgia, lethargy.
Multiple prescriptions taken:
  • Docetaxel (145mg Cyclic)
  • Simvastatin (40mg At Night)
  • Aspirin (75mg Per Day)
  • Sodium Docusate (200mg Twice Per Day)
  • Calcium Carbonate
  • Enoxaparin Sodium
  • Fluconazole
  • Colchicine
Patient was hospitalized.

Herpes Zoster (8212262-3)
on Mar 06, 2012 Male from CANADA , weighting 169.8 lb, was treated with Domperidone. After Domperidone was administered, patient encountered several Domperidone side effects: herpes zoster. Domperidone dosage: N/A.
Multiple concurrent drugs taken:
  • Norvasc
  • Remicade
  • Pantoprazole Sodium
  • Avalide
  • Remicade


Dyskinesia, Dry Mouth, Tooth Fracture, Tongue Disorder, Dizziness, Salivary Hypersecretion, Photophobia, Headache (8197363-0)
on Mar 01, 2012 Female from BRAZIL , 32 years of age, weighting 127.9 lb, was diagnosed with
  • gastritis
and was treated with Domperidone. Directly after, patient experienced the unwanted or unexpected Domperidone side effects: dyskinesia, dry mouth, tooth fracture, tongue disorder, dizziness, salivary hypersecretion, photophobia, headache. Domperidone dosage: Started 5 Months Prior To The Report Date.
Associated medications used:
  • Lansoprazole (Started 5 Months Prior To The Report Date)
  • Haldol
Patient was hospitalized.

Showing 1-25 of 158 

Domperidone Health Episodes

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Domperidone Information

More About Domperidone

Side Effects reported to FDA: 158. View Domperidone Adverse Reports

Domperidone safety alerts: 2004

Reported deaths: 28

Reported hospitalizations: 70

Domperidone

Audience: Consumers and healthcare professionals

FDA warned healthcare professionals and breastfeeding women not to use an unapproved drug, domperidone, to increase milk production (lactation). The agency is concerned with the potential public health risks associated with domperidone. FDA took these actions because it has become aware that some women are purchasing this drug from compounding pharmacies and from foreign sources. Although domperidone is approved in several countries outside the U.S. to treat certain gastric disorders, it is not approved in any country, including the U.S., for enhancing breast milk production in lactating women and is also not approved in the U.S. for any indication.

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