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Doxycycline Side Effects

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Common Doxycycline Side Effects


The most commonly reported Doxycycline side effects (click to view or check a box to report):

Headache (127)
Nausea (125)
Rash (81)
Dyspnoea (80)
Dizziness (80)
Pain (80)
Vomiting (80)
Diarrhoea (67)
Haemorrhage (66)
Malaise (64)
Abortion Incomplete (63)
Chest Pain (60)
Anxiety (57)
Oesophageal Ulcer (52)
Pyrexia (50)
Asthenia (48)
Fatigue (47)
Abdominal Pain Upper (45)
Pruritus (44)
Photosensitivity Reaction (43)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Doxycycline Side Effects Reported to FDA



Doxycycline Side Effect Report#9937025
Vascular Injury, Oesophageal Ulcer, Oesophagitis
This is a report of a 27-year-old female patient (weight: NA) from CA, suffering from the following health symptoms/conditions: urinary tract infection, who was treated with Doxycycline (dosage: NA, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Vascular Injury, Oesophageal Ulcer, Oesophagitis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Doxycycline treatment in female patients, resulting in Vascular Injury side effect.
Doxycycline Side Effect Report#9933101
Pancreatitis
This report suggests a potential Doxycycline Pancreatitis side effect(s) that can have serious consequences. A 54-year-old female patient (weight: NA) from DE was diagnosed with the following symptoms/conditions: atypical pneumonia and used Doxycycline (dosage: Daily Dose: 200 Mg Millgram(s) Every Days) starting NS. After starting Doxycycline the patient began experiencing various side effects, including: PancreatitisAdditional drugs used concurrently:
  • Cefuroxime (Daily Dose: 2 Df Dosage Form Every Days)
  • Caprelsa (Daily Dose: 300 Mg Millgram(s) Every Days)
The patient was hospitalized. Although Doxycycline demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Pancreatitis, may still occur.
Doxycycline Side Effect Report#9931613
Nausea, Headache, Disinhibition, Affect Lability, Irritability, Anxiety, Depressed Mood, Social Avoidant Behaviour, Indifference
This Nausea problem was reported by a physician from GB. A 33-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: acne. On NS this consumer started treatment with Doxycycline Hyclate (dosage: NA). The following drugs were being taken at the same time: NA. When using Doxycycline Hyclate, the patient experienced the following unwanted symptoms/side effects: Nausea, Headache, Disinhibition, Affect Lability, Irritability, Anxiety, Depressed Mood, Social Avoidant Behaviour, IndifferenceAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Nausea, may become evident only after a product is in use by the general population.
Doxycycline Side Effect Report#9931583
Suicidal Ideation, Mood Swings, Disinhibition, Irritability, Depressed Mood, Mental Status Changes, Nausea
This Suicidal Ideation side effect was reported by a health professional from GB. A 33-year-old female patient (weight:NA) experienced the following symptoms/conditions: acne.The patient was prescribed Doxycycline (drug dosage: One Time), which was initiated on NS. Concurrently used drugs: NA..After starting to take Doxycycline the consumer reported adverse symptoms, such as: Suicidal Ideation, Mood Swings, Disinhibition, Irritability, Depressed Mood, Mental Status Changes, NauseaThese side effects may potentially be related to Doxycycline.
Doxycycline Side Effect Report#9929051
Haemoglobin Decreased, Gastrointestinal Haemorrhage
This is a report of a 81-year-old female patient (weight: NA) from GB, suffering from the following health symptoms/conditions: pneumonia, who was treated with Doxycycline (dosage: 100 Milligram Daily; Morning, start time:
Feb 05, 2014), combined with:
  • Prednisolone (Morning)
  • Amlodipine
  • Aspirin (Witheld)
  • Co-codamol
  • Ferrous Fumarate
  • Folic Acid
  • Lansoprazole (15 Milligram Daily;)
  • Lansoprazole (30 Milligram Daily;)
and developed a serious reaction and side effect(s): Haemoglobin Decreased, Gastrointestinal Haemorrhage after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Doxycycline treatment in female patients, resulting in Haemoglobin Decreased side effect. The patient was hospitalized.
Doxycycline Side Effect Report#9928701
Suicidal Ideation, Completed Suicide
This report suggests a potential Doxycycline Suicidal Ideation side effect(s) that can have serious consequences. A 19-year-old male patient (weight: NA) from GB was diagnosed with the following symptoms/conditions: dermatitis and used Doxycycline (dosage: NA) starting NS. After starting Doxycycline the patient began experiencing various side effects, including: Suicidal Ideation, Completed SuicideAdditional drugs used concurrently: NA. Although Doxycycline demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Suicidal Ideation, may still occur.
Doxycycline Side Effect Report#9928487
Asthenia, Dizziness, Nausea, Malaise, Constipation
This Asthenia problem was reported by a pharmacist from US. A 73-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: sinusitis. On
Jan 23, 2014 this consumer started treatment with Doxycycline (dosage: NA). The following drugs were being taken at the same time: NA. When using Doxycycline, the patient experienced the following unwanted symptoms/side effects: Asthenia, Dizziness, Nausea, Malaise, ConstipationThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Asthenia, may become evident only after a product is in use by the general population.
Doxycycline Side Effect Report#9928372
Haemoglobin Decreased
This Haemoglobin Decreased side effect was reported by a pharmacist from GB. A 81-year-old female patient (weight:NA) experienced the following symptoms/conditions: pneumonia.The patient was prescribed Doxycycline Monohydrate (drug dosage: 100 Mg, 1x/day), which was initiated on
Feb 05, 2014. Concurrently used drugs:
  • Prednisolone (Morning)
  • Amlodipine
  • Acetylsalicylic Acid (Witheld)
  • Co-codamol
  • Ferrous Fumarate
  • Folic Acid
  • Lansoprazole (15 Mg, 1x/day)
  • Ramipril
.After starting to take Doxycycline Monohydrate the consumer reported adverse symptoms, such as: Haemoglobin DecreasedThese side effects may potentially be related to Doxycycline Monohydrate. The patient was hospitalized.
Doxycycline Side Effect Report#9926200
Headache, Dizziness
This is a report of a 51-year-old female patient (weight: NA) from GB, suffering from the following health symptoms/conditions: NA, who was treated with Doxycycline (dosage: NA, start time:
Jan 29, 2014), combined with: NA. and developed a serious reaction and side effect(s): Headache, Dizziness after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Doxycycline treatment in female patients, resulting in Headache side effect.
Doxycycline Side Effect Report#9926122
Suicidal Ideation, Panic Attack, Depressed Mood
This report suggests a potential Doxycycline Hyclate Suicidal Ideation side effect(s) that can have serious consequences. A 15-year-old male patient (weight: NA) from NL was diagnosed with the following symptoms/conditions: chlamydial infection and used Doxycycline Hyclate (dosage: 100 Mg, 2x/day) starting 2011. After starting Doxycycline Hyclate the patient began experiencing various side effects, including: Suicidal Ideation, Panic Attack, Depressed MoodAdditional drugs used concurrently:
  • Venlafaxine (150 Mg, 1x/day)
Although Doxycycline Hyclate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Suicidal Ideation, may still occur.
Doxycycline Side Effect Report#9926014
Headache, Dizziness
This Headache problem was reported by a physician from GB. A 51-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Jan 29, 2014 this consumer started treatment with Doxycycline (dosage: NA). The following drugs were being taken at the same time: NA. When using Doxycycline, the patient experienced the following unwanted symptoms/side effects: Headache, DizzinessAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Headache, may become evident only after a product is in use by the general population.
Doxycycline Side Effect Report#9925147
Lupus-like Syndrome, Musculoskeletal Stiffness, Arthralgia, Movement Disorder, Gait Disturbance, Nausea, Headache, Confusional State
This Lupus-like Syndrome side effect was reported by a consumer or non-health professional from US. A 59-year-old female patient (weight:NA) experienced the following symptoms/conditions: acne.The patient was prescribed Doxycycline (drug dosage: 1 Pill Twice Daily), which was initiated on
Oct 30, 2013. Concurrently used drugs: NA..After starting to take Doxycycline the consumer reported adverse symptoms, such as: Lupus-like Syndrome, Musculoskeletal Stiffness, Arthralgia, Movement Disorder, Gait Disturbance, Nausea, Headache, Confusional StateThese side effects may potentially be related to Doxycycline. The patient was hospitalized.
Doxycycline Side Effect Report#9924030
Deafness, Hypoacusis, Autophony
This is a report of a 78-year-old female patient (weight: NA) from GB, suffering from the following health symptoms/conditions: infection, who was treated with Doxycycline Hyclate (dosage: 199 Mg, Daily, start time:
Apr 23, 2012), combined with: NA. and developed a serious reaction and side effect(s): Deafness, Hypoacusis, Autophony after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Doxycycline Hyclate treatment in female patients, resulting in Deafness side effect.
Doxycycline Side Effect Report#9922483
Iiird Nerve Injury, Diplopia, Vith Nerve Paralysis
This report suggests a potential Doxycycline Iiird Nerve Injury side effect(s) that can have serious consequences. A 52-year-old female patient (weight: NA) from GB was diagnosed with the following symptoms/conditions: NA and used Doxycycline (dosage: NA) starting
Jan 09, 2014. After starting Doxycycline the patient began experiencing various side effects, including: Iiird Nerve Injury, Diplopia, Vith Nerve ParalysisAdditional drugs used concurrently: NA. Although Doxycycline demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Iiird Nerve Injury, may still occur.
Doxycycline Side Effect Report#9921976
Night Sweats, Palpitations, Migraine, Diarrhoea, Nausea, Decreased Appetite, Hypoaesthesia, Anxiety, Paranoia
This Night Sweats problem was reported by a consumer or non-health professional from US. A 30-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: rosacea. On NS this consumer started treatment with Doxycycline Hyclate (dosage: 2.5 Weeks , 18 Days). The following drugs were being taken at the same time: NA. When using Doxycycline Hyclate, the patient experienced the following unwanted symptoms/side effects: Night Sweats, Palpitations, Migraine, Diarrhoea, Nausea, Decreased Appetite, Hypoaesthesia, Anxiety, ParanoiaThe patient was hospitalized and became disabled.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Night Sweats, may become evident only after a product is in use by the general population.
Doxycycline Side Effect Report#9921749
Idiopathic Angioedema, Deformity, Mass, Flushing, Idiopathic Urticaria, Skin Discolouration, Pyrexia, Oropharyngeal Pain
This Idiopathic Angioedema side effect was reported by a consumer or non-health professional from US. A female patient (weight:NA) experienced the following symptoms/conditions: idiopathic angioedema,deformity,mass,flushing,idiopathic urticaria,skin discolouration,off label use.The patient was prescribed Doxycycline Tablets (drug dosage: NA), which was initiated on NS. Concurrently used drugs: NA..After starting to take Doxycycline Tablets the consumer reported adverse symptoms, such as: Idiopathic Angioedema, Deformity, Mass, Flushing, Idiopathic Urticaria, Skin Discolouration, Pyrexia, Oropharyngeal PainThese side effects may potentially be related to Doxycycline Tablets.
Doxycycline Side Effect Report#9920779
Iiird Nerve Injury, Diplopia, Vith Nerve Paralysis
This is a report of a 52-year-old female patient (weight: NA) from GB, suffering from the following health symptoms/conditions: NA, who was treated with Doxycycline (dosage: NA, start time:
Jan 09, 2014), combined with: NA. and developed a serious reaction and side effect(s): Iiird Nerve Injury, Diplopia, Vith Nerve Paralysis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Doxycycline treatment in female patients, resulting in Iiird Nerve Injury side effect.
Doxycycline Side Effect Report#9920219
Dizziness, Headache
This report suggests a potential Doxycycline Dizziness side effect(s) that can have serious consequences. A 51-year-old female patient (weight: NA) from GB was diagnosed with the following symptoms/conditions: NA and used Doxycycline (dosage: 100 Mg, Unk) starting
Jan 29, 2014. After starting Doxycycline the patient began experiencing various side effects, including: Dizziness, HeadacheAdditional drugs used concurrently: NA. Although Doxycycline demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Dizziness, may still occur.
Doxycycline Side Effect Report#9909121
Headache, Dizziness
This Headache problem was reported by a physician from GB. A 51-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Jan 29, 2014 this consumer started treatment with Doxycycline Monohydrate (dosage: 100 Mg, Unk). The following drugs were being taken at the same time: NA. When using Doxycycline Monohydrate, the patient experienced the following unwanted symptoms/side effects: Headache, DizzinessAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Headache, may become evident only after a product is in use by the general population.
Doxycycline Side Effect Report#9909094
Suicidal Ideation, Completed Suicide, Malaise, Depressed Mood
This Suicidal Ideation side effect was reported by a health professional from GB. A 18-year-old male patient (weight:NA) experienced the following symptoms/conditions: acne.The patient was prescribed Doxycycline (drug dosage: 50 Mg/day For 1y), which was initiated on 201202. Concurrently used drugs: NA..After starting to take Doxycycline the consumer reported adverse symptoms, such as: Suicidal Ideation, Completed Suicide, Malaise, Depressed MoodThese side effects may potentially be related to Doxycycline.
Doxycycline Side Effect Report#9909076
Suicidal Ideation, Completed Suicide
This is a report of a 19-year-old male patient (weight: NA) from GB, suffering from the following health symptoms/conditions: dermatitis, who was treated with Doxycycline (dosage: 100 Milligram Daily;, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Suicidal Ideation, Completed Suicide after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Doxycycline treatment in male patients, resulting in Suicidal Ideation side effect.
Doxycycline Side Effect Report#9904745
Suicidal Ideation, Nausea, Headache, Mood Swings
This report suggests a potential Doxycycline Suicidal Ideation side effect(s) that can have serious consequences. A 33-year-old female patient (weight: NA) from GB was diagnosed with the following symptoms/conditions: acne and used Doxycycline (dosage: 200mg Stat; Then 100mg Once Daily) starting NS. After starting Doxycycline the patient began experiencing various side effects, including: Suicidal Ideation, Nausea, Headache, Mood SwingsAdditional drugs used concurrently: NA. Although Doxycycline demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Suicidal Ideation, may still occur.
Doxycycline Side Effect Report#9901396
Iiird Nerve Injury, Diplopia, Vith Nerve Paralysis
This Iiird Nerve Injury problem was reported by a physician from GB. A 52-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Jan 09, 2014 this consumer started treatment with Doxycycline Monohydrate (dosage: Unk). The following drugs were being taken at the same time: NA. When using Doxycycline Monohydrate, the patient experienced the following unwanted symptoms/side effects: Iiird Nerve Injury, Diplopia, Vith Nerve ParalysisAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Iiird Nerve Injury, may become evident only after a product is in use by the general population.
Doxycycline Side Effect Report#9901248
Diplopia, Iiird Nerve Injury, Vith Nerve Paralysis
This Diplopia side effect was reported by a health professional from GB. A 52-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Doxycycline (drug dosage: NA), which was initiated on
Jan 09, 2014. Concurrently used drugs: NA..After starting to take Doxycycline the consumer reported adverse symptoms, such as: Diplopia, Iiird Nerve Injury, Vith Nerve ParalysisThese side effects may potentially be related to Doxycycline.
Doxycycline Side Effect Report#9899548
Suicidal Ideation, Mood Swings, Nausea, Headache
This is a report of a 33-year-old female patient (weight: NA) from GB, suffering from the following health symptoms/conditions: acne, who was treated with Doxycycline (dosage: 200mg Stat; Then 100mg Once Daily, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Suicidal Ideation, Mood Swings, Nausea, Headache after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Doxycycline treatment in female patients, resulting in Suicidal Ideation side effect.


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The appearance of Doxycycline on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

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What are common Doxycycline Side Effects for Women?

Women Side EffectsReports
Headache 95
Nausea 89
Haemorrhage 64
Pain 64
Vomiting 64
Abortion Incomplete 63
Dizziness 62
Rash 51
Dyspnoea 48
Diarrhoea 46

What are common Doxycycline Side Effects for Men?

Men Side EffectsReports
Headache 32
Dyspnoea 31
Nausea 31
Rash 28
Anxiety 24
Malaise 23
Stevens-johnson Syndrome 22
Completed Suicide 20
Pyrexia 19
Renal Failure Acute 19

Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Doxycycline reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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    Discuss Doxycycline Side Effects

    Did You Have a Doxycycline Side Effect?

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    Yes, Moderate
    Yes, Minor
    No

    How Effective is Doxycycline for You?

    Exceeded Expectations
    Effective
    Somewhat Effective
    Not Effective

    Doxycycline Safety Alerts, Active Ingredients, Usage Information

    NDC0069-0104
    TypeHUMAN PRESCRIPTION DRUG
    Proprietary NameDoxycycline
    NameDOXYCYCLINE HYCLATE
    Dosage FormINJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
    RouteINTRAVENOUS
    On market since20120821
    LabelerPfizer Laboratories Div Pfizer Inc
    Active Ingredient(s)DOXYCYCLINE HYCLATE
    Strength(s)100
    Unit(s)mg/10mL
    Pharma Class

    Doxycycline Dosage, Warnings, Usage.

    Side Effects reported to FDA: 1757

    Doxycycline safety alerts: 2001

    Reported deaths: 72

    Reported hospitalizations: 480

    Latest Doxycycline clinical trials