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Doxycycline Side Effects

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Common Doxycycline Side Effects


The most commonly reported Doxycycline side effects (click to view or check a box to report):

Headache (127)
Nausea (125)
Rash (81)
Dyspnoea (80)
Dizziness (80)
Pain (80)
Vomiting (80)
Diarrhoea (67)
Haemorrhage (66)
Malaise (64)
Abortion Incomplete (63)
Chest Pain (60)
Anxiety (57)
Oesophageal Ulcer (52)
Pyrexia (50)
Asthenia (48)
Fatigue (47)
Abdominal Pain Upper (45)
Pruritus (44)
Photosensitivity Reaction (43)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Doxycycline Side Effects Reported to FDA



Doxycycline Side Effect Report#9997924
Pancreatitis
This is a report of a 54-year-old female patient (weight: NA) from DE, suffering from the following health symptoms/conditions: atypical pneumonia,thyroid cancer, who was treated with Doxycycline (dosage: Daily Dose: 200 Mg Millgram(s) Every Days, start time: NS), combined with:
  • Caprelsa (Daily Dose: 300 Mg Millgram(s) Every Days)
  • Cefuroxime (Daily Dose: 2 Df Dosage Form Every Days)
and developed a serious reaction and side effect(s): Pancreatitis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Doxycycline treatment in female patients, resulting in Pancreatitis side effect. The patient was hospitalized.
Doxycycline Side Effect Report#9995940
Pancreatitis
This report suggests a potential Doxycycline Pancreatitis side effect(s) that can have serious consequences. A 54-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: sinusitis and used Doxycycline (dosage: NA) starting NS. After starting Doxycycline the patient began experiencing various side effects, including: PancreatitisAdditional drugs used concurrently: NA.The patient was hospitalized. Although Doxycycline demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Pancreatitis, may still occur.
Doxycycline Side Effect Report#9994918
Rash, Swelling, Chest Pain, Abdominal Pain, Weight Decreased, Nausea, Decreased Appetite, Photosensitivity Reaction, Pain
This Rash problem was reported by a consumer or non-health professional from US. A 41-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: sexually transmitted disease. On
Feb 02, 2014 this consumer started treatment with Doxycycline 100mg Watson Labs (dosage: NA). The following drugs were being taken at the same time: NA. When using Doxycycline 100mg Watson Labs, the patient experienced the following unwanted symptoms/side effects: Rash, Swelling, Chest Pain, Abdominal Pain, Weight Decreased, Nausea, Decreased Appetite, Photosensitivity Reaction, PainAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Rash, may become evident only after a product is in use by the general population.
Doxycycline Side Effect Report#9993279
Pain, Pyrexia
This Pain side effect was reported by a health professional from IN. A 37-year-old female patient (weight:NA) experienced the following symptoms/conditions: limb injury.The patient was prescribed Doxycycline (drug dosage: One Dose), which was initiated on NS. Concurrently used drugs: NA..After starting to take Doxycycline the consumer reported adverse symptoms, such as: Pain, PyrexiaThese side effects may potentially be related to Doxycycline. The patient was hospitalized.
Doxycycline Side Effect Report#9991888
Vith Nerve Paralysis, Diplopia
This is a report of a 62-year-old male patient (weight: NA) from GB, suffering from the following health symptoms/conditions: NA, who was treated with Doxycycline Monohydrate (dosage: Unk, start time:
Nov 27, 2013), combined with:
  • Amoxicillin (Unk)
  • Cefalexin (Unk)
and developed a serious reaction and side effect(s): Vith Nerve Paralysis, Diplopia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Doxycycline Monohydrate treatment in male patients, resulting in Vith Nerve Paralysis side effect.
Doxycycline Side Effect Report#9989362
Diplopia, Vith Nerve Paralysis
This report suggests a potential Doxycycline Diplopia side effect(s) that can have serious consequences. A 62-year-old male patient (weight: NA) from GB was diagnosed with the following symptoms/conditions: NA and used Doxycycline (dosage: NA) starting
Nov 27, 2013. After starting Doxycycline the patient began experiencing various side effects, including: Diplopia, Vith Nerve ParalysisAdditional drugs used concurrently:
  • Amoxicillin
  • Cefalexin
Although Doxycycline demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Diplopia, may still occur.
Doxycycline Side Effect Report#9988638
Dermatitis Bullous
This Dermatitis Bullous problem was reported by a health professional from IN. A 37-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Doxycycline (dosage: Unk). The following drugs were being taken at the same time: NA. When using Doxycycline, the patient experienced the following unwanted symptoms/side effects: Dermatitis BullousAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Dermatitis Bullous, may become evident only after a product is in use by the general population.
Doxycycline Side Effect Report#9981285
Haemoglobin Decreased
This Haemoglobin Decreased side effect was reported by a pharmacist from GB. A 81-year-old female patient (weight:NA) experienced the following symptoms/conditions: pneumonia.The patient was prescribed Doxycycline (drug dosage: Morning), which was initiated on
Feb 05, 2014. Concurrently used drugs:
  • Prednisolone (Morning)
  • Amlodipine
  • Aspirin (Witheld)
  • Co-codamol
  • Ferrous Fumarate
  • Folic Acid
  • Lansoprazole
  • Ramipril
.After starting to take Doxycycline the consumer reported adverse symptoms, such as: Haemoglobin DecreasedThese side effects may potentially be related to Doxycycline. The patient was hospitalized.
Doxycycline Side Effect Report#9981249
Suicidal Ideation, Anxiety
This is a report of a 50-year-old male patient (weight: NA) from GB, suffering from the following health symptoms/conditions: infection, who was treated with Doxycycline (dosage: NA, start time:
Oct 22, 2013), combined with:
  • Omeprazole
  • Lisinopril
and developed a serious reaction and side effect(s): Suicidal Ideation, Anxiety after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Doxycycline treatment in male patients, resulting in Suicidal Ideation side effect.
Doxycycline Side Effect Report#9981113
Gynaecomastia
This report suggests a potential Doxycycline Monohydrate Gynaecomastia side effect(s) that can have serious consequences. A 73-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: rash and used Doxycycline Monohydrate (dosage: 250 Mg Per 500 Ml Or 1 G - 100 Mg Caps; 1 Capsule) starting
Feb 04, 2014. After starting Doxycycline Monohydrate the patient began experiencing various side effects, including: GynaecomastiaAdditional drugs used concurrently: NA. Although Doxycycline Monohydrate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Gynaecomastia, may still occur.
Doxycycline Side Effect Report#9972484
Completed Suicide
This Completed Suicide problem was reported by a health professional from GB. A 19-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: dermatitis. On NS this consumer started treatment with Doxycycline (dosage: NA). The following drugs were being taken at the same time: NA. When using Doxycycline, the patient experienced the following unwanted symptoms/side effects: Completed SuicideAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Completed Suicide, may become evident only after a product is in use by the general population.
Doxycycline Side Effect Report#9972353
Completed Suicide
This Completed Suicide side effect was reported by a health professional from GB. A 19-year-old male patient (weight:NA) experienced the following symptoms/conditions: dermatitis.The patient was prescribed Doxycycline (drug dosage: NA), which was initiated on NS. Concurrently used drugs: NA..After starting to take Doxycycline the consumer reported adverse symptoms, such as: Completed SuicideThese side effects may potentially be related to Doxycycline.
Doxycycline Side Effect Report#9972341
Malaise, Depressed Mood, Impaired Work Ability, Depressed Mood, Completed Suicide, Asphyxia
This is a report of a 18-year-old male patient (weight: NA) from GB, suffering from the following health symptoms/conditions: acne, who was treated with Doxycycline (dosage: NA, start time: 2010), combined with: NA. and developed a serious reaction and side effect(s): Malaise, Depressed Mood, Impaired Work Ability, Depressed Mood, Completed Suicide, Asphyxia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Doxycycline treatment in male patients, resulting in Malaise side effect.
Doxycycline Side Effect Report#9972257
Nausea, Headache, Disinhibition, Irritability, Anxiety, Depressed Mood, Suicidal Ideation, Social Avoidant Behaviour, Indifference
This report suggests a potential Doxycycline Nausea side effect(s) that can have serious consequences. A 33-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: acne and used Doxycycline (dosage: NA) starting NS. After starting Doxycycline the patient began experiencing various side effects, including: Nausea, Headache, Disinhibition, Irritability, Anxiety, Depressed Mood, Suicidal Ideation, Social Avoidant Behaviour, IndifferenceAdditional drugs used concurrently: NA. Although Doxycycline demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Nausea, may still occur.
Doxycycline Side Effect Report#9971486
Myalgia, Fatigue, Nausea, Muscle Spasms, Constipation, Malaise, Gait Disturbance
This Myalgia problem was reported by a consumer or non-health professional from US. A 31-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: endometritis. On
Feb 27, 2014 this consumer started treatment with Doxycycline (dosage: Taken By Mouth). The following drugs were being taken at the same time: NA. When using Doxycycline, the patient experienced the following unwanted symptoms/side effects: Myalgia, Fatigue, Nausea, Muscle Spasms, Constipation, Malaise, Gait DisturbanceAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Myalgia, may become evident only after a product is in use by the general population.
Doxycycline Side Effect Report#9970254
Depressed Mood, Completed Suicide, Asphyxia
This Depressed Mood side effect was reported by a consumer or non-health professional from WF. A 18-year-old male patient (weight:NA) experienced the following symptoms/conditions: acne.The patient was prescribed Doxycycline (drug dosage: NA), which was initiated on 2010. Concurrently used drugs: NA..After starting to take Doxycycline the consumer reported adverse symptoms, such as: Depressed Mood, Completed Suicide, AsphyxiaThese side effects may potentially be related to Doxycycline.
Doxycycline Side Effect Report#9969966
Erythema Multiforme, Renal Injury
This is a report of a 64-year-old male patient (weight: NA) from CO, suffering from the following health symptoms/conditions: malaria prophylaxis, who was treated with Doxycycline (dosage: NA, start time: NS), combined with:
  • Hydrochlorothiazide
  • Lisinopril
  • Meloxicam
and developed a serious reaction and side effect(s): Erythema Multiforme, Renal Injury after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Doxycycline treatment in male patients, resulting in Erythema Multiforme side effect. The patient was hospitalized.
Doxycycline Side Effect Report#9969586
Burning Sensation
This report suggests a potential Doxycycline Burning Sensation side effect(s) that can have serious consequences. A 29-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: NA and used Doxycycline (dosage: NA) starting
Feb 22, 2014. After starting Doxycycline the patient began experiencing various side effects, including: Burning SensationAdditional drugs used concurrently:
  • Depakote
  • Pepcid
  • Haldol
  • Norco
  • Lisinopril
  • Ambien
Although Doxycycline demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Burning Sensation, may still occur.
Doxycycline Side Effect Report#9964384
Pancreatitis, Pneumonia, Renal Failure Acute
This Pancreatitis problem was reported by a health professional from DE. A 54-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: atypical pneumonia. On NS this consumer started treatment with Doxycycline (dosage: 200mg Per Day). The following drugs were being taken at the same time:
  • Cefuroxime
  • Caprelsa (300mg Per Day)
When using Doxycycline, the patient experienced the following unwanted symptoms/side effects: Pancreatitis, Pneumonia, Renal Failure AcuteThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Pancreatitis, may become evident only after a product is in use by the general population.
Doxycycline Side Effect Report#9960566
Tendonitis
This Tendonitis side effect was reported by a consumer or non-health professional from US. A 66-year-old female patient (weight:NA) experienced the following symptoms/conditions: sinusitis.The patient was prescribed Doxycycline Hyclate (drug dosage: NA), which was initiated on
Jan 29, 2014. Concurrently used drugs: NA..After starting to take Doxycycline Hyclate the consumer reported adverse symptoms, such as: TendonitisThese side effects may potentially be related to Doxycycline Hyclate.
Doxycycline Side Effect Report#9951069
Vomiting, Pain, Circulatory Collapse, Hypotension
This is a report of a 63-year-old female patient (weight: NA) from GB, suffering from the following health symptoms/conditions: sinusitis, who was treated with Doxycycline Monohydrate (dosage: 100 Mg, 2x/day, start time:
Jan 22, 2014), combined with:
  • Citalopram (20 Mg, Unk)
  • Paracetamol (Unk)
  • Pramipexole (0.089 Mg, Unk)
and developed a serious reaction and side effect(s): Vomiting, Pain, Circulatory Collapse, Hypotension after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Doxycycline Monohydrate treatment in female patients, resulting in Vomiting side effect. The patient was hospitalized.
Doxycycline Side Effect Report#9950800
Pancreatitis, Renal Failure Acute, Atypical Pneumonia
This report suggests a potential Doxycycline Hyclate Pancreatitis side effect(s) that can have serious consequences. A 54-year-old female patient (weight: NA) from DE was diagnosed with the following symptoms/conditions: atypical pneumonia and used Doxycycline Hyclate (dosage: 200 Mg, 1x/day) starting NS. After starting Doxycycline Hyclate the patient began experiencing various side effects, including: Pancreatitis, Renal Failure Acute, Atypical PneumoniaAdditional drugs used concurrently:
  • Cefuroxime (1 Df, 2x/day)
  • Caprelsa (300 Mg, 1x/day)
The patient was hospitalized. Although Doxycycline Hyclate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Pancreatitis, may still occur.
Doxycycline Side Effect Report#9949722
Hypersensitivity, Rash
This Hypersensitivity problem was reported by a consumer or non-health professional from US. A 54-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: rosacea. On 2011 this consumer started treatment with Doxycycline (dosage: NA). The following drugs were being taken at the same time:
  • Metrogel (metronidazole) Gel, 1%
  • Oracea (doxycycline, Usp) Capsule 40mg
  • Benadryl
When using Doxycycline, the patient experienced the following unwanted symptoms/side effects: Hypersensitivity, RashAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Hypersensitivity, may become evident only after a product is in use by the general population.
Doxycycline Side Effect Report#9945845
Haemoglobin Decreased
This Haemoglobin Decreased side effect was reported by a health professional from GB. A 81-year-old female patient (weight:NA) experienced the following symptoms/conditions: pneumonia.The patient was prescribed Doxycycline (drug dosage: 100 Mg, Qd, Morning), which was initiated on
Feb 05, 2014. Concurrently used drugs:
  • Prednisolone (30 Mg, Qd, Morning)
  • Amlodipine
  • Aspirin
  • Co-codamol
  • Ferrous Fumarate
  • Acido Folico
  • Lansoprazole (15 Mg, Qd)
  • Lansoprazole (30 Mg, Qd)
.After starting to take Doxycycline the consumer reported adverse symptoms, such as: Haemoglobin DecreasedThese side effects may potentially be related to Doxycycline. The patient was hospitalized.
Doxycycline Side Effect Report#9937027
Vascular Injury, Oesophageal Ulcer, Oesophagitis
This is a report of a 26-year-old male patient (weight: NA) from CA, suffering from the following health symptoms/conditions: acne, who was treated with Doxycycline (dosage: NA, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Vascular Injury, Oesophageal Ulcer, Oesophagitis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Doxycycline treatment in male patients, resulting in Vascular Injury side effect.


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The appearance of Doxycycline on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

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What are common Doxycycline Side Effects for Women?

Women Side EffectsReports
Headache 95
Nausea 89
Haemorrhage 64
Pain 64
Vomiting 64
Abortion Incomplete 63
Dizziness 62
Rash 51
Dyspnoea 48
Diarrhoea 46

What are common Doxycycline Side Effects for Men?

Men Side EffectsReports
Headache 32
Dyspnoea 31
Nausea 31
Rash 28
Anxiety 24
Malaise 23
Stevens-johnson Syndrome 22
Completed Suicide 20
Pyrexia 19
Renal Failure Acute 19

Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Doxycycline reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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    Discuss Doxycycline Side Effects

    Did You Have a Doxycycline Side Effect?

    Yes, Severe
    Yes, Moderate
    Yes, Minor
    No

    How Effective is Doxycycline for You?

    Exceeded Expectations
    Effective
    Somewhat Effective
    Not Effective

    Doxycycline Safety Alerts, Active Ingredients, Usage Information

    NDC0069-0104
    TypeHUMAN PRESCRIPTION DRUG
    Proprietary NameDoxycycline
    NameDOXYCYCLINE HYCLATE
    Dosage FormINJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
    RouteINTRAVENOUS
    On market since20120821
    LabelerPfizer Laboratories Div Pfizer Inc
    Active Ingredient(s)DOXYCYCLINE HYCLATE
    Strength(s)100
    Unit(s)mg/10mL
    Pharma Class

    Doxycycline Dosage, Warnings, Usage.

    Side Effects reported to FDA: 1757

    Doxycycline safety alerts: 2001

    Reported deaths: 72

    Reported hospitalizations: 480

    Public Health Advisory: Doxycycline for Anthrax Exposure

    Audience: Health professionals and general public

    FDA reminds all health professionals and the general public that Doxycycline is approved for the treatment of anthrax in all its forms. The FDA is providing additional information concerning the dosing regimen for the treatment of anthrax, including cutaneous and inhalation anthrax (post-exposure). The currently recommended dosage regimen of doxycycline for severe disease is 100 mg every 12 hours for adults and 1mg per pound (2.2mg per kilogram) every 12 hours for children less than 100 pounds. These dosage regimens are appropriate for use in patients who have been exposed to anthrax (Bacillus anthracis) regardless of the route of exposure.

    [Oct 18, 2001 - Public Health Advisory - FDA]

    Latest Doxycycline clinical trials