Drotrecogin Side Effects summary

Total Drotrecogin reports: 41. View

Drotrecogin FDA safety alerts: 2005 2009 .

Reported deaths: 11

Reported hospitalizations: 12.

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Recently reported Drotrecogin Side Effects


Common Drotrecogin Side Effects
Gastrointestinal haemorrhage 20%
Haemorrhage 20%
Haemorrhage intracranial 10%
Anaemia 7%
Coma 7%
Multi-organ failure 7%
Acute respiratory distress syndrome 5%
Cerebrovascular accident 5%
Coagulopathy 5%
Epistaxis 5%
Haemodialysis 5%
Intraventricular haemorrhage 5%
Localised intraabdominal fluid collection 5%
Sepsis  What is  Sepsis                                                                                                                                                                                                  5%
Subarachnoid haemorrhage 5%
Thrombocytopenia 5%
Abdominal haematoma 2%
Activated partial thromboplastin time prolonged 2%
Angiopathy 2%
Anoxic encephalopathy 2%
Anxiety  What is  Anxiety                                                                                                                                                                                                 2%
Bile duct obstruction 2%
Blood bilirubin increased 2%
Bone marrow tumour cell infiltration 2%
Brain oedema 2%
Brain stem haemorrhage 2%
Caesarean section 2%
Candidiasis 2%
Cardiac arrest  What is  Cardiac arrest                                                                                                                                                                                          2%
Cardio-respiratory arrest 2%
Cardio-respiratory distress 2%
Catheter related complication 2%
Catheter site haemorrhage 2%
Cerebellar haemorrhage 2%
Cerebral haemorrhage 2%
Cerebral ischaemia 2%
Chest x-ray abnormal 2%
Circulatory collapse 2%
Clostridium difficile colitis 2%
Continuous haemodiafiltration 2%
Convulsion 2%
Coronary artery disease  What is  Coronary artery disease                                                                                                                                                                                 2%
Depression  What is  Depression                                                                                                                                                                                              2%
Disorientation 2%
Diverticular perforation 2%
Dyspnoea 2%
Ecchymosis 2%
Faecal occult blood positive 2%
Gastric ulcer 2%
Gastritis haemorrhagic 2%
Gastrointestinal disorder 2%
Haematemesis 2%
Haematocrit decreased 2%
Haematuria 2%
Hysterectomy  What is  Hysterectomy                                                                                                                                                                                            2%
Intra-abdominal haemorrhage 2%
Ischaemic cerebral infarction 2%
Leg amputation 2%
Leukocytosis 2%
Lower respiratory tract infection 2%
Lymphoma  What is  Lymphoma                                                                                                                                                                                                2%
Malignant neoplasm progression 2%
Maternal condition affecting foetus 2%
Mean arterial pressure decreased 2%
Melaena 2%
Mental status changes 2%
Mouth haemorrhage 2%
Myocardial ischaemia 2%
Necrosis 2%
Platelet count increased 2%
Post procedural bile leak 2%
Post procedural complication 2%
Premature labour 2%
Pseudomonas infection 2%
Pulmonary embolism  What is  Pulmonary embolism                                                                                                                                                                                      2%
Pulmonary oedema 2%
Rales 2%
Renal failure 2%
Renal impairment 2%
Secretion discharge 2%
Stridor 2%
Subdural haemorrhage 2%
Swelling face 2%
Swollen tongue 2%
Toxic epidermal necrolysis 2%
Wheezing 2%

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Drotrecogin Side Effects Report #5349500-0
Physician from AUSTRIA reported Drotrecogin side effect on May 29, 2007. Male patient, 48 years of age, was diagnosed with staphylococcal sepsis and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: bone marrow tumour cell infiltration, malignant neoplasm progression, pulmonary embolism What is  pulmonary embolism. Drotrecogin dosage: unknown. Patient died.



Drotrecogin Side Effects Report #5352623-3
Drotrecogin side effect was reported by a Physician from UNITED KINGDOM on May 30, 2007. Male patient, 31 years of age, weighting 165.3 lb, was diagnosed with sepsis What is  sepsis, hypotension, pneumonia What is  pneumonia, sedation, analgesic effect and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, chest x-ray abnormal, lower respiratory tract infection, rales. Drotrecogin dosage: 0.024 MG/KG, EVERY HOUR. During the same period patient was treated with NORADRENALINE, RANITIDINE, HYDROCORTISONE, TAZOCIN, METRONIDAZOLE, PROPOFOL, MORPHINE, MIDAZOLAM. Patient recovered.



Drotrecogin Side Effects Report #5370256-X
Pharmacist from UNITED STATES reported Drotrecogin side effect on June 25, 2007. Male patient, 38 years of age, weighting 357.1 lb, was diagnosed with sepsis What is  sepsis and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: cardio-respiratory arrest, haemorrhage. Drotrecogin dosage: unknown. Patient died on 06/07/2007.



Drotrecogin Side Effects Report #5371743-0
Drotrecogin side effect was reported by a Physician from DENMARK on June 18, 2007. Female patient, 48 years of age, weighting 114.6 lb, was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: cardiac arrest What is  cardiac arrest, lymphoma What is  lymphoma. Drotrecogin dosage: unknown. Patient died on 02/27/2007.




Drotrecogin Side Effects Report #5066287-X
Pharmacist from UNITED STATES reported Drotrecogin side effect on July 31, 2006. Female patient, 48 years of age, weighting 140.0 lb, was diagnosed with urosepsis and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: haemorrhage. Drotrecogin dosage: unknown. Patient was hospitalized and became disabled. Patient recovered.



Drotrecogin Side Effects Report #5097516-4
Drotrecogin side effect was reported by a Physician from INDIA on Aug 17, 2006. Male patient, 55 years of age, was diagnosed with sepsis What is  sepsis and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: convulsion, haemorrhage intracranial. Drotrecogin dosage: unknown. During the same period patient was treated with ANTIBIOTICS. Patient was hospitalized. Patient recovered.



Drotrecogin Side Effects Report #5104506-1
Physician from POLAND reported Drotrecogin side effect on Aug 21, 2006. Female patient, 32 years of age, was diagnosed with septic shock and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: anaemia, caesarean section, coagulopathy, haemorrhage, hysterectomy What is  hysterectomy, maternal condition affecting foetus, multi-organ failure, premature labour. Drotrecogin dosage: unknown. Patient was hospitalized. Patient recovered.



Drotrecogin Side Effects Report #5107558-8
Drotrecogin side effect was reported by a Pharmacist from UNITED STATES on Sept 13, 2006. Female patient, 50 years of age, weighting 176.4 lb, was diagnosed with organ failure, sepsis syndrome and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: cerebral ischaemia, intraventricular haemorrhage, subarachnoid haemorrhage, subdural haemorrhage. Drotrecogin dosage: unknown. During the same period patient was treated with DROTRECOGIN ALFA. Patient was hospitalized. Patient recovered.



Drotrecogin Side Effects Report #5503149-5
Physician from HUNGARY reported Drotrecogin side effect on Oct 24, 2007. Male patient, 62 years of age, weighting 286.6 lb, was diagnosed with septic shock and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: cardio-respiratory distress, catheter site haemorrhage. Drotrecogin dosage: 20 MG, OTHER. During the same period patient was treated with POTASSIUM CHLORIDE, FUROSEMIDE, SORTIS, ASPIRIN, DIOVAN, NEBILET. Patient died on 09/28/2007.




Drotrecogin Side Effects Report #5526373-4
Drotrecogin side effect was reported by a Pharmacist from UNITED STATES on Nov 21, 2007. Male patient, 59 years of age, was diagnosed with neutropenic sepsis, septic shock and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: haemorrhage. Drotrecogin dosage: 20MG ONCE IV. During the same period patient was treated with DROTRECOGIN ALFA. Patient was hospitalized. Patient recovered.



Drotrecogin Side Effects Report #5545612-7
Consumer or non-health professional from CANADA reported Drotrecogin side effect on Nov 23, 2007. Male patient, weighting 176.4 lb, was diagnosed with sepsis What is  sepsis, hypotension, blood glucose, prophylaxis, myocardial ischaemia, hypothyroidism and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: localised intraabdominal fluid collection. Drotrecogin dosage: unknown. During the same period patient was treated with LEVOPHED, HUMULIN, ZANTAC, PIPERACILLIN W, NORVASC, LIPITOR, ASPIRIN, SYNTHROID. Patient recovered.



Drotrecogin Side Effects Report #5580395-6
Drotrecogin side effect was reported by a Consumer or non-health professional from CANADA on Dec 20, 2007. Male patient, weighting 176.4 lb, was diagnosed with sepsis What is  sepsis, hypotension, blood glucose, prophylaxis, myocardial ischaemia, hypothyroidism and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: localised intraabdominal fluid collection. Drotrecogin dosage: unknown. During the same period patient was treated with LEVOPHED, HUMULIN, ZANTAC, PIPERACILLIN W, NORVASC, LIPITOR, ASPIRIN, SYNTHROID. Patient recovered.



Drotrecogin Side Effects Report #5777095-6
Consumer or non-health professional from UNITED STATES reported Drotrecogin side effect on June 17, 2008. Female patient, weighting 197.3 lb, was diagnosed with sepsis What is  sepsis and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: clostridium difficile colitis, coagulopathy, diverticular perforation, haemorrhage, sepsis What is  sepsis. Drotrecogin dosage: unknown. During the same period patient was treated with HYDROCORTISONE, CEFEPIME, DILTIAZEM, LOVENOX, METOPROLOL, METRONIDAZOLE, PROTONIX, VANCOMYCIN. Patient recovered.



Drotrecogin Side Effects Report #5825771-9
Drotrecogin side effect was reported by a Pharmacist from UNITED STATES on July 28, 2008. Female patient was diagnosed with urinary tract infection What is  urinary tract infection and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: anxiety What is  anxiety, disorientation, dyspnoea, stridor, swelling face, swollen tongue, wheezing. Drotrecogin dosage: 2 MG Q1H IV. Patient recovered.




Drotrecogin Side Effects Report #5999760-8
Physician from FRANCE reported Drotrecogin side effect on Dec 05, 2008. Male patient, weighting 158.7 lb, was diagnosed with septic shock and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: coma. Drotrecogin dosage: unknown. During the same period patient was treated with KARDEGIC, NORADRENALINE, HYPNOVEL, SUFENTA PRESERVATIVE FREE, UMULINE, HYDROCORTISONE, LASIX, TIENAM. Patient recovered.



Drotrecogin Side Effects Report #6055320-4
Drotrecogin side effect was reported by a Physician from FRANCE on Jan 19, 2009. Male patient, weighting 158.7 lb, was diagnosed with septic shock and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: coma. Drotrecogin dosage: unknown. During the same period patient was treated with KARDEGIC, NORADRENALINE, MIDAZOLAM, SUFENTA PRESERVATIVE FREE, UMULINE, HYDROCORTISONE, LASILIX, TIENAM. Patient recovered.



Drotrecogin Side Effects Report #6089635-0
Pharmacist from UNITED STATES reported Drotrecogin side effect on Feb 19, 2009. Male patient, 57 years of age, weighting 156.5 lb, was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, anaemia, anoxic encephalopathy, brain oedema, continuous haemodiafiltration, haemodialysis, haemorrhage intracranial, ischaemic cerebral infarction, leukocytosis. Drotrecogin dosage: unknown. Patient died on 02/10/2009.



Drotrecogin Side Effects Report #6094806-3
Drotrecogin side effect was reported by a Physician from FRANCE on Feb 13, 2009. Male patient, weighting 158.7 lb, was diagnosed with septic shock and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: coma, haemorrhage intracranial. Drotrecogin dosage: unknown. During the same period patient was treated with KARDEGIC, NORADRENALINE, MIDAZOLAM, SUFENTA PRESERVATIVE FREE, UMULINE, HYDROCORTISONE, LASIX, TIENAM. Patient recovered.



Drotrecogin Side Effects Report #6107446-4
Physician from FRANCE reported Drotrecogin side effect on Feb 27, 2009. Female patient was diagnosed with sepsis What is  sepsis, pain What is  pain, hypothyroidism and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: circulatory collapse. Drotrecogin dosage: 0.024 MG/KG, EVERY HOUR. During the same period patient was treated with VOLUVEN, DOBUTREX, TAZOCILLINE, PERFALGAN, LEVOXYL. Patient died on 11/24/2006.




Drotrecogin Side Effects Report #6137163-6
Drotrecogin side effect was reported by a Physician from FRANCE on Mar 25, 2009. Female patient, weighting 147.7 lb, was diagnosed with sepsis What is  sepsis, sedation and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: cerebrovascular accident. Drotrecogin dosage: unknown. During the same period patient was treated with HYPNOVEL, SUFENTA PRESERVATIVE FREE. Patient died on 01/17/2008.



Drotrecogin Side Effects Report #6137443-4
Physician from FRANCE reported Drotrecogin side effect on Mar 25, 2009. Female patient, weighting 147.7 lb, was diagnosed with sepsis What is  sepsis, sedation and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: cerebrovascular accident. Drotrecogin dosage: unknown. During the same period patient was treated with HYPNOVEL, SUFENTA PRESERVATIVE FREE. Patient died on 01/17/2008.



Drotrecogin Side Effects Report #4566530-7
Drotrecogin side effect was reported by a Pharmacist from on Jan 26, 2005. Male patient, 76 years of age, weighting 257.9 lb, was diagnosed with multi-organ failure, sepsis What is  sepsis and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: abdominal haematoma, bile duct obstruction, blood bilirubin increased, haemodialysis, intra-abdominal haemorrhage, multi-organ failure, post procedural bile leak, post procedural complication, renal failure. Drotrecogin dosage: unknown. During the same period patient was treated with DROTRECOGIN ALFA, HEPARIN, DOBUTAMINE, NOREPINEPHRINE, ERYTHROPOETIN ALPHA, PANTOPRAZOLE, CVVHD, CITRATE ANTICOAGULANT. Patient was hospitalized. Patient died on 09/15/2003.



Drotrecogin Side Effects Report #4588504-2
Pharmacist from reported Drotrecogin side effect on Feb 15, 2005. Male patient, 47 years of age, weighting 330.7 lb, was diagnosed with multi-organ failure, septic shock and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: catheter related complication, platelet count increased, secretion discharge. Drotrecogin dosage: unknown. During the same period patient was treated with DROTRECOGIN ALFA, LEVOFLOXACIN, VANCOMYCIN, OXACILLIN, DOPAMINE, NOREPINEPHRINE, PROPOFOL, ESMOLOL. Patient recovered.



Drotrecogin Side Effects Report #4608472-4
Drotrecogin side effect was reported by a Pharmacist from on Mar 11, 2005. Female patient was diagnosed with sepsis What is  sepsis and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: haemorrhage. Drotrecogin dosage: unknown. Patient recovered.




Drotrecogin Side Effects Report #4608483-9
Pharmacist from reported Drotrecogin side effect on Mar 11, 2005. Male patient was diagnosed with sepsis What is  sepsis and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: epistaxis, gastrointestinal haemorrhage. Drotrecogin dosage: unknown. Patient recovered.



Drotrecogin Side Effects Report #4630939-3
Drotrecogin side effect was reported by a Pharmacist from on Apr 07, 2005. Male patient, 43 years of age, weighting 233.2 lb, was diagnosed with sepsis What is  sepsis and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: anaemia, thrombocytopenia. Drotrecogin dosage: 60MG, 30MGQ12H, INFUSION. Patient was hospitalized. Patient recovered.



Drotrecogin Side Effects Report #4636145-0
Pharmacist from reported Drotrecogin side effect on Apr 14, 2005. Male patient, weighting 172.0 lb, was diagnosed with sepsis What is  sepsis and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: faecal occult blood positive, haematocrit decreased, mean arterial pressure decreased, melaena. Drotrecogin dosage: 24 MG/KG/HR. Patient was hospitalized. Patient recovered.



Drotrecogin Side Effects Report #4638670-5
Drotrecogin side effect was reported by a Pharmacist from on Apr 15, 2005. Female patient, 60 years of age, was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, gastrointestinal haemorrhage, haematemesis, multi-organ failure. Drotrecogin dosage: unknown. Patient recovered.



Drotrecogin Side Effects Report #4654611-9
Pharmacist from reported Drotrecogin side effect on May 03, 2005. Female patient, 77 years of age, weighting 134.5 lb, was diagnosed with bacterial sepsis and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage. Drotrecogin dosage: unknown. During the same period patient was treated with HEPARIN, ACETAMINOPHEN, DUONEB, CIPRO, CALCIUM GLUCONATE, HYDROCORTISONE. Patient recovered.




Drotrecogin Side Effects Report #4727015-8
Drotrecogin side effect was reported by a Pharmacist from UNITED STATES on July 26, 2005. Male patient was diagnosed with sepsis What is  sepsis and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: gastrointestinal disorder, mouth haemorrhage. Drotrecogin dosage: unknown. Patient recovered.



Drotrecogin Side Effects Report #4767236-1
Pharmacist from UNITED STATES reported Drotrecogin side effect on Sept 09, 2005. Female patient, 81 years of age, weighting 171.7 lb, was diagnosed with escherichia sepsis and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: angiopathy, gastric ulcer, gastritis haemorrhagic, gastrointestinal haemorrhage. Drotrecogin dosage: unknown. During the same period patient was treated with PANTOPRAZOLE, LEVOFLOXACIN, NOREPINEPHRINE, METRONIDAZOLE, CEFTRIAXONE. Patient recovered.



Drotrecogin Side Effects Report #4774531-9
Drotrecogin side effect was reported by a Pharmacist from UNITED STATES on Sept 19, 2005. Female patient, 49 years of age, weighting 255.7 lb, was diagnosed with septic shock and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: ecchymosis, toxic epidermal necrolysis. Drotrecogin dosage: unknown. During the same period patient was treated with VANCOMYCIN, TOBRAMYCIN, HYDROCORTISONE, CIPROFLOXACIN, METRONIDAZOLE, RANITIDINE, PANTOPRAZOLE, HEPARIN. Patient was hospitalized. Patient recovered.



Drotrecogin Side Effects Report #4797309-9
Pharmacist from UNITED STATES reported Drotrecogin side effect on Oct 11, 2005. Male patient, 84 years of age, weighting 110.2 lb, was diagnosed with septic shock, urosepsis and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage. Drotrecogin dosage: unknown. During the same period patient was treated with DROTRECOGIN ALFA, FAMOTIDINE. Patient recovered.



Drotrecogin Side Effects Report #4844594-0
Drotrecogin side effect was reported by a Physician from INDIA on Nov 16, 2005. Male patient, 67 years of age, was diagnosed with sepsis What is  sepsis and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: candidiasis, coronary artery disease What is  coronary artery disease, myocardial ischaemia, pseudomonas infection, pulmonary oedema. Drotrecogin dosage: unknown. During the same period patient was treated with SYSCAN, ASPIRIN. Patient was hospitalized. Patient recovered.




Drotrecogin Side Effects Report #4872524-4
Pharmacist from UNITED STATES reported Drotrecogin side effect on Dec 30, 2005. Male patient, 52 years of age, weighting 224.9 lb, was diagnosed with escherichia sepsis and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: cerebellar haemorrhage, epistaxis. Drotrecogin dosage: unknown. Patient died on 11/30/2005.



Drotrecogin Side Effects Report #4881668-2
Drotrecogin side effect was reported by a Pharmacist from UNITED STATES on Jan 12, 2006. Male patient was diagnosed with sepsis What is  sepsis and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage. Drotrecogin dosage: unknown. Patient recovered.



Drotrecogin Side Effects Report #4881808-5
Pharmacist from UNITED STATES reported Drotrecogin side effect on Jan 12, 2006. Male patient was diagnosed with sepsis What is  sepsis and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage. Drotrecogin dosage: unknown. Patient recovered.



Drotrecogin Side Effects Report #4903350-5
Drotrecogin side effect was reported by a Pharmacist from UNITED STATES on Feb 06, 2006. Female patient was diagnosed with sepsis What is  sepsis and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: brain stem haemorrhage, mental status changes. Drotrecogin dosage: unknown. Patient recovered.



Drotrecogin Side Effects Report #4921259-8
Pharmacist from UNITED STATES reported Drotrecogin side effect on Feb 22, 2006. Female patient, 66 years of age, weighting 111.1 lb, was diagnosed with sepsis What is  sepsis, thrombosis prophylaxis and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, depression What is  depression, gastrointestinal haemorrhage, renal impairment, sepsis What is  sepsis, thrombocytopenia. Drotrecogin dosage: unknown. During the same period patient was treated with ENOXAPARIN. Patient was hospitalized. Patient died on 02/13/2006.




Drotrecogin Side Effects Report #4955855-9
Drotrecogin side effect was reported by a Health Professional from UNITED STATES on Mar 27, 2006. Male patient, 64 years of age, weighting 151.0 lb, was diagnosed with pneumonia What is  pneumonia, sepsis What is  sepsis and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: haematuria. Drotrecogin dosage: unknown. Patient recovered.



Drotrecogin Side Effects Report #4999441-3
Consumer or non-health professional from UNITED STATES reported Drotrecogin side effect on May 09, 2006. Female patient was diagnosed with sepsis What is  sepsis and was treated with Drotrecogin. After drug was administered, patient experienced the following side effects: haemorrhage intracranial, intraventricular haemorrhage, leg amputation, necrosis, subarachnoid haemorrhage. Drotrecogin dosage: unknown. During the same period patient was treated with ACETAMINOPHEN, CEFEPIME, CEFAZOLIN, INSULIN, DOCUSATE, FENTANYL, HYDROCORTISONE, METRONIDAZOLE. Patient was hospitalized and became disabled. Patient recovered.





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