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Dyazide Side Effects

Common Dyazide Side Effects


The most commonly reported Dyazide side effects (click to view or check a box to report):

Nausea (19)
Diarrhoea (12)
Headache (11)
Dizziness (11)
Oedema Peripheral (10)
Hypoaesthesia (9)
Dyspnoea (8)
Blood Pressure Increased (8)
Muscle Spasms (8)
Vomiting (8)
Blood Sodium Decreased (7)
Asthenia (7)
Blood Potassium Decreased (7)
Chest Pain (7)
Pruritus (7)
Joint Swelling (6)
Fall (6)
Pain In Extremity (6)
Rash (6)
Malaise (6)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

Dyazide Side Effects Reported to FDA

The following Dyazide reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.


The appearance of Dyazide on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.
Pneumonia, Hyponatraemia, Nausea
This is a report of a 56-year-old female patient (weight: NA) from US, suffering from the following symptoms/conditions: NA, who was treated with Dyazide (dosage: NA, start time: NS), combined with: NA. and developed a serious reaction and side effect(s). The consumer presented with:
  • Pneumonia
  • Hyponatraemia
  • Nausea
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Dyazide treatment in female patients, resulting in pneumonia side effect. The patient was hospitalized.

Local Swelling, Chest Pain
This report suggests a potential Dyazide Local Swelling, Chest Pain side effect(s) that can have serious consequences. A 51-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: hypertension,nerve injury and used Dyazide (dosage: NA) starting 201301. Soon after starting Dyazide the patient began experiencing various side effects, including:
  • Local Swelling
  • Chest Pain
Drugs used concurrently:
  • Lyrica (300mg Twice Per Day)
  • Lisinopril (40mg Per Day)
Although Dyazide demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as local swelling, may still occur.

Nausea, Eating Disorder, Abdominal Pain Upper, Frequent Bowel Movements, Dizziness, Condition Aggravated
This Nausea, Eating Disorder, Abdominal Pain Upper, Frequent Bowel Movements, Dizziness, Condition Aggravated problem was reported by a consumer or non-health professional from US. A 77-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: polyuria. On 201205 this consumer started treatment with Dyazide (dosage: 1cap Per Day). The following drugs were being taken at the same time:
  • Hydrochlorothiazide\triamterene (1cap Per Day)
  • Avapro
  • Synthroid
  • Lantus
  • Humalog
  • Hydrocodone
  • Famotidine
  • Zolpidem Tartrate
When commencing Dyazide, the patient experienced the following unwanted symptoms/side effects:
  • Nausea
  • Eating Disorder
  • Abdominal Pain Upper
  • Frequent Bowel Movements
  • Dizziness
  • Condition Aggravated
Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as nausea, may become evident only after a product is in use by the general population.

Muscle Spasms, Hypoaesthesia, Pain In Extremity, Sensory Disturbance, Arthralgia, Feeling Abnormal, Paraesthesia
This is a report of a male patient (weight: NA) from US. The patient developed the following symptoms/conditions: NA and was treated with Dyazide (dosage: 27.5 Lowering And Or Anything Else, Ignored.) starting NS. Concurrently used drugs: NA.Soon after that, the consumer experienced the following side effects:
  • Muscle Spasms
  • Hypoaesthesia
  • Pain In Extremity
  • Sensory Disturbance
  • Arthralgia
  • Feeling Abnormal
  • Paraesthesia
This opens a possibility that Dyazide treatment could cause the above reactions, including muscle spasms, and some male subjects may be more susceptible.


Deafness Unilateral, Syncope
A 67-year-old male patient (weight: NA) from US with the following symptoms/conditions: deafness,cardiovascular disorder started Dyazide treatment (dosage: NA) on Mar 30, 2010. Soon after starting Dyazide treatment, the subject experienced various side effects, including:
  • Deafness Unilateral
  • Syncope
Concurrently used drugs: NA.The patient was hospitalized and became disabled. This finding indicates that some male patients could be more vulnerable to Dyazide.

Retinal Detachment, Metabolic Encephalopathy, Gait Disturbance, Glaucoma
A 57-year-old male patient from US (weight: NA) experienced symptoms, such as: NA and was treated with Dyazide(dosage: NA). The treatment was initiated on Aug 31, 2007. After that a consumer reported the following side effect(s):
  • Retinal Detachment
  • Metabolic Encephalopathy
  • Gait Disturbance
  • Glaucoma
Concurrently used drugs, which potentially could have contributed to side effect(s) or affected Dyazide efficacy:
  • Peginterferon Alfa-2a (360ug Weekly)
  • Ribavirin (1400mg Per Day)
  • Aciphex
  • Prednisone (80mg Per Day)
  • Cymbalta
  • Lamictal
  • Keppra
  • Singular
The patient was hospitalized and became disabled.

Renal Failure Acute, Dehydration, Hyperuricaemia, Platelet Count Decreased
In this report, Dyazide was administered for the following condition: NA.A 70-year-old male consumer from US (weight: NA) started Dyazide treatment (dosage: NA) on Jun 27, 2011.Sometime after starting the treatment, the patient complained of the following side effect(s):
  • Renal Failure Acute
  • Dehydration
  • Hyperuricaemia
  • Platelet Count Decreased
A possible interaction with other drugs could have contributed to this reaction:
  • Metformin
  • Sunitinib (37.5mg Per Day)
  • Bevacizumab (5mgk Cyclic)
  • Hctz
The patient was hospitalized.Establishing a causal relationship between a specific drug and consumer's side effects is complex, but it is possible that in this report Dyazide treatment could be related to the listed above side effect(s).

Renal Disorder, Blood Creatinine Increased, Renal Function Test Abnormal
This is a report of the following Dyazide side effect(s):
  • Renal Disorder
  • Blood Creatinine Increased
  • Renal Function Test Abnormal
A 79-year-old female patient from UNITED STATES (weight: NA) presented with the following condition: NA and received a treatment with Dyazide (dosage: NA) starting: Mar 04, 2009.The following concurrently used drugs could have generated interactions:
  • Fosinopril Sodium
  • Exjade (1250 Mg, Qd, Oral 2000 Mg Qd, Oral 1500 Mg, Qd, Oral)
  • Exjade (1250 Mg, Qd, Oral 2000 Mg Qd, Oral 1500 Mg, Qd, Oral)
  • Exjade (1250 Mg, Qd, Oral 2000 Mg Qd, Oral 1500 Mg, Qd, Oral)
  • Exjade (1250 Mg, Qd, Oral 2000 Mg Qd, Oral 1500 Mg, Qd, Oral)
This report suggests that a Dyazide treatment could be associated with the listed above side effect(s).

Blood Urea Increased, Blood Creatinine Increased, Glomerular Filtration Rate Decreased, Renal Failure
This Dyazide report was submitted by a 68-year-old female consumer from UNITED STATES (weight: NA). The patient was diagnosed with: NA and Dyazide was administered (dosage: NA) starting: May 12, 2009. The consumer developed a set of symptoms:
  • Blood Urea Increased
  • Blood Creatinine Increased
  • Glomerular Filtration Rate Decreased
  • Renal Failure
Other drugs used simultaneously:
  • Asacol
  • Nexium
  • Exjade (1500 Mg, Qd, Oral; 1250 Mg Daily, Oral)
Those unexpected symptoms could be linked to a Dyazide treatment, however establishing a potential drug-safety problem requires a more detailed clinical analysis.

Chronic Lymphocytic Leukaemia Refractory
This is a report of a possible correlation between Dyazide use and the following symptoms/side effect(s):
  • Chronic Lymphocytic Leukaemia Refractory
which could contribute to an assessment of Dyazide risk profile.A 80-year-old female consumer from UNITED STATES (weight: NA) was suffering from NA and was treated with Dyazide (dosage: NA) starting Apr 27, 2007.Other concurrent medications:
  • Prilosec
  • Prednisone Tab
  • Exjade (1000 Mg, Qd, Oral)


Mastectomy, Nausea, Cardiac Disorder, Blood Cholesterol Increased, Anxiety, Tremor, Breast Cancer, Depression, Breast Mass
A 64-year-old female patient from UNITED STATES (weight: NA) presented with the following symptoms: meniere's disease and after a treatment with Dyazide (dosage: Unk) experienced the following side effect(s):
  • Mastectomy
  • Nausea
  • Cardiac Disorder
  • Blood Cholesterol Increased
  • Anxiety
  • Tremor
  • Breast Cancer
  • Depression
  • Breast Mass
The treatment was started on Jan 01, 1985. Dyazide was used in combination with the following drugs:
  • Lovastatin
  • Provera (2.5 Mg, Unk)
  • Testim (Unk)
  • Estratest (1.25 Mg, Unk)
  • Inderal (Unk)
  • Inderal (Unk)
  • Acyclovir
  • Clonazepam
This report could alert potential Dyazide consumers.

Gait Disturbance, Ventricular Extrasystoles, Nausea, Spinal Column Stenosis, Chest Pain, Bursitis, Intervertebral Disc Protrusion, No Therapeutic Response
In this report, a 56-year-old female patient from UNITED STATES (weight: NA) was affected by a possible Dyazide (hydroichlorothiazide, Triamterene) side effect.The patient was diagnosed with NA. After a treatment with Dyazide (hydroichlorothiazide, Triamterene) (dosage: NA, start date: Jan 01, 2009), the patient experienced the following side effect(s):
  • Gait Disturbance
  • Ventricular Extrasystoles
  • Nausea
  • Spinal Column Stenosis
  • Chest Pain
  • Bursitis
  • Intervertebral Disc Protrusion
  • No Therapeutic Response
The following simultaneously used drugs could have led to this reaction:
  • Calcium + D (calcium, Ergocalciferol)
  • Ambien Cr
  • Actonel (150 Mg Once Monthly, Oral)
  • Temazepam
  • Hydrocodone Bitartrate
  • Vitamin B12
  • Premarin Vaginal (esrogens Conjugated)
  • Synthroid
The patient was hospitalized.The findings here stress that side effects should be taken into consideration when evaluating a Dyazide (hydroichlorothiazide, Triamterene) treatment.

Blood Potassium Decreased, Intervertebral Disc Protrusion, Limb Discomfort, Thrombosis
This is a report of a female patient from UNITED STATES (weight: NA), who used Dyazide (dosage: Unk) for a treatment of hypertension,nerve injury. After starting a treatment on Jan 01, 2010, the patient experienced the following side effect(s):
  • Blood Potassium Decreased
  • Intervertebral Disc Protrusion
  • Limb Discomfort
  • Thrombosis
The following drugs could possibly have interacted with the Dyazide treatment
  • Lyrica (75 Mg, 2x/day)
  • Atenolol (Unk)
  • Lipitor (40 Mg, 1x/day)
  • Lyrica
Taken together, these observations suggest that a Dyazide treatment could be related to side effect(s), such as Blood Potassium Decreased, Intervertebral Disc Protrusion, Limb Discomfort, Thrombosis.

Arthralgia
This arthralgia side effect was reported by a physician from UNITED STATES. A male patient (weight:NA) experienced the following symptoms/conditions: hypertension,acromegaly. The patient was prescribed Dyazide (dosage: Unk), which was started on Mar 20, 2008. Concurrently used drugs:
  • Pegvisomant (10 Mg, Alternate Day Injection)
  • Pegvisomant (10 Mg, Alternate Day)
  • Calcium (Unk)
  • Valsartan (Unk)
  • Valsartan (Unk)
  • Prilosec (Unk)
When starting to take Dyazide the consumer reported the following symptoms:
  • Arthralgia
These side effects may potentially be related to Dyazide.

Pancreatitis
This is a Dyazide (hydrochlorothiazide) side effect report of a 77-year-old male patient (weight:NA) from UNITED STATES, suffering from the following symptoms/conditions: NA, who was treated with Dyazide (hydrochlorothiazide) (dosage:NA, start time: Mar 30, 2012), combined with:
  • Brentuximab Vedotin (brentuximab Vedotin) Injection (1.8 Mg/kg, Q21d, Intravenous)
  • Diltiazem Hydrochloride
  • Metoprolol Tartrate
  • Allopurinol
  • Celexa
, and developed a serious reaction and a pancreatitis side effect. The patient presented with:
  • Pancreatitis
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Dyazide (hydrochlorothiazide) treatment in male patients suffering from NA, resulting in pancreatitis.

Tremor, Neutropenia, Cellulitis, Pyrexia, Thermal Burn, Platelet Count Decreased, Pneumonia
This report suggests a potential Dyazide tremor side effect(s) that can have serious consequences. A 73-year-old female patient from UNITED STATES (weight:NA) was diagnosed with the following health condition(s): NA and used Dyazide (dosage: NA) starting Jan 01, 2011. Soon after starting Dyazide the patient began experiencing various side effects, including:
  • Tremor
  • Neutropenia
  • Cellulitis
  • Pyrexia
  • Thermal Burn
  • Platelet Count Decreased
  • Pneumonia
Drugs used concurrently:
  • Centrum (centrum)
  • Lecithin (lecithin)
  • Prevacid
  • Velcade
  • Coumadin
  • L-carnitine (levocarnitine Hydrochloride)
  • Fish Oil (fish Oil)
  • Lisinopril
The patient was hospitalized. Although Dyazide demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as tremor, may still occur.

Pneumonia, Arthralgia, Joint Swelling
This pneumonia problem was reported by a physician from UNITED STATES. A 56-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Jan 24, 2009 a consumer started treatment with Dyazide (dosage: NA). The following drugs/medications were being taken at the same time:
  • Gleevec (400 Mg, Qd, Oral)
  • Zantac
  • Advair Hfa
  • Albuterol
When commencing Dyazide, the patient experienced the following unwanted symptoms /side effects:
  • Pneumonia
  • Arthralgia
  • Joint Swelling
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as pneumonia, may become evident only after a product is in use by the general population.

Nasal Congestion
This is a Dyazide side effect report of a 60-year-old male patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: hypertension,erectile dysfunction and was treated with Dyazide (dosage: Unk) starting NS. Concurrently used drugs:
  • Viagra (12.5 Mg, As Needed)
Soon after that, the consumer experienced the following of symptoms:
  • Nasal Congestion
This opens a possibility that Dyazide could cause nasal congestion and that some male patients may be more susceptible.

Back Pain, Pain In Extremity, Surgery
A female patient (weight: NA) from CANADA with the following symptoms: NA started Dyazide treatment (dosage: NA) on Apr 01, 2005. Soon after starting Dyazide treatment, the consumer experienced several side effects, including:
  • Back Pain
  • Pain In Extremity
  • Surgery
. Concurrently used drugs:
  • Fosamax
  • Methotrexate
  • Ramipril
  • Remicade
  • Metoprolol Succinate
  • Prednisone Tab
  • Vitamin D
This finding indicates that some patients can be more vulnerable to developing Dyazide side effects, such as back pain.

Neoplasm Malignant
This neoplasm malignant side effect was reported by a physician from UNITED STATES. A female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Dyazide (dosage: Unk), which was started on Jan 11, 2012. Concurrently used drugs:
  • Tenormin (Unk)
  • Mevacor (Unk)
  • Calcium (Unk)
  • Folic Acid (Unk)
  • Prevacid (Unk)
  • Aspirin (Unk)
  • Erlotinib Hydrochloride (150 Mg, Uid/qd)
  • Diovan (Unk)
.When starting to take Dyazide the consumer reported symptoms, such as:
  • Neoplasm Malignant
These side effects may potentially be related to Dyazide.

Muscular Weakness, Dyspnoea
This is a report of a male patient (weight: NA) from UNITED STATES, suffering from the following symptoms/conditions: NA, who was treated with Dyazide (dosage: NA, start time: NS), combined with:
  • Casodex (5850 Mg)
  • Xalatan
  • Aspirin
  • Calcium Plus D3
  • Plavix
  • Multi-vitamins
  • Lisinopril
  • Zocor
and developed a serious reaction and side effect(s). The consumer presented with:
  • Muscular Weakness
  • Dyspnoea
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Dyazide treatment in male patients, resulting in muscular weakness side effect. The patient was hospitalized.


This report suggests a potential Dyazide side effect(s) that can have serious consequences. A female patient (weight: NA) from UNITED STATES was diagnosed with the following symptoms/conditions: NA and used Dyazide (dosage: Unk) starting Jan 11, 2012. Soon after starting Dyazide the patient began experiencing various side effects, including:
    Drugs used concurrently:
    • Prednisone (Unk)
    • Tenormin (Unk)
    • Diovan (Unk)
    • Mevacor (Unk)
    • Invirase (Unk)
    • Pepcid (Unk)
    • Prevacid (Unk)
    • Calcium (Unk)
    Although Dyazide demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as death, may still occur.

    Splenomegaly, Abdominal Pain, Lymphoma, Urinary Tract Infection, Cholelithiasis
    This Splenomegaly, Abdominal Pain, Lymphoma, Urinary Tract Infection, Cholelithiasis problem was reported by a physician from UNITED STATES. A 70-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: hypertension,medical diet,psoriatic arthropathy,pain. On Jan 01, 2009 this consumer started treatment with Dyazide (dosage: Dose: 37.5mg/25mg). The following drugs were being taken at the same time:
    • Folic Acid
    • Methotrexate
    • Percocet (5-325 Mg. 1-2 Tabs Every 6 Hours As Needed.)
    • Certolizumab Pegol
    • Xanax
    • Flexeril (10 Mg. 1 Tablet Every 8 Hours)
    • Amaryl
    • Prilosec (20mg Daily)
    When commencing Dyazide, the patient experienced the following unwanted symptoms/side effects:
    • Splenomegaly
    • Abdominal Pain
    • Lymphoma
    • Urinary Tract Infection
    • Cholelithiasis
    The patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as splenomegaly, may become evident only after a product is in use by the general population.

    Pulmonary Oedema, Cardiac Failure, Cardiomegaly, Ventricular Septal Defect, Atrial Septal Defect
    This is a report of a male patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: NA and was treated with Dyazide (dosage: 375 Mg, Every 7 Hours) starting Aug 14, 2009. Concurrently used drugs:
    • Valtrex (Unk)
    • Flegyl (50 Mg, 2x/day)
    • Multi-vitamins (Unk)
    • Zoloft (100 Mg, Every Day)
    • Aldomet (250 Mg, 2x/day)
    • Claritin (As Needed)
    Soon after that, the consumer experienced the following side effects:
    • Pulmonary Oedema
    • Cardiac Failure
    • Cardiomegaly
    • Ventricular Septal Defect
    • Atrial Septal Defect
    The patient was hospitalized. This opens a possibility that Dyazide treatment could cause the above reactions, including pulmonary oedema, and some male subjects may be more susceptible.

    Asthenia, Hypersomnia, Hyperlipidaemia, Nephropathy
    A female patient (weight: NA) from UNITED STATES with the following symptoms/conditions: hypertension,neurogenic bladder started Dyazide treatment (dosage: NA) on Dec 29, 2006. Soon after starting Dyazide treatment, the subject experienced various side effects, including:
    • Asthenia
    • Hypersomnia
    • Hyperlipidaemia
    • Nephropathy
    Concurrently used drugs:
    • Detrol La
    • Estratest
    • Medizine
    • Lisinopril
    • Rebif
    This finding indicates that some female patients could be more vulnerable to Dyazide.

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    Keep Track of Side Effects

    Note Your Observations

    It is really important to keep of your symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

    Why Your Notes are Important

    Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


    Discuss Dyazide Side Effects

    Did You Have a Dyazide Side Effect?

    Yes, Severe
    Yes, Moderate
    Yes, Minor
    No

    How Effective is Dyazide for You?

    Exceeded Expectations
    Effective
    Somewhat Effective
    Not Effective

    Dyazide Safety Alerts, Active Ingredients, Usage Information

    NDC0007-3650
    TypeHUMAN PRESCRIPTION DRUG
    Proprietary NameDYAZIDE
    Namehydrochlorothiazide and triamterene
    Dosage FormCAPSULE
    RouteORAL
    On market since19940330
    LabelerGlaxoSmithKline LLC
    Active Ingredient(s)HYDROCHLOROTHIAZIDE; TRIAMTERENE
    Strength(s)25; 37.5
    Unit(s)mg/1; mg/1
    Pharma ClassIncreased Diuresis [PE],Thiazide Diuretic [EPC],Thiazides [Chemical/Ingredient],Decreased Renal K+ E

    Dyazide Dosage, Warnings, Usage.

    Side Effects reported to FDA: 205

    Dyazide safety alerts: No

    Reported deaths: 14

    Reported hospitalizations: 55

    Latest Dyazide clinical trials