Common Effexor Side Effects


The most commonly reported Effexor side effects (click to view or check a box to report):

Dizziness (702)
Anxiety (595)
Nausea (594)
Depression (503)
Headache (495)
Feeling Abnormal (492)
Suicidal Ideation (449)
Condition Aggravated (436)
Paraesthesia (372)
Malaise (353)
Insomnia (349)
Fatigue (286)
Crying (285)
Confusional State (269)
Agitation (265)
Hyperhidrosis (263)
Asthenia (249)
Tremor (236)
Diarrhoea (236)
Convulsion (235)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Effexor Side Effects Reported to FDA



Effexor Side Effect Report#9928839
Somnolence
This is a report of a 59-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: NA, who was treated with Effexor (dosage: Unk, start time: NS), combined with:
  • Effexor Xr (Unk)
and developed a serious reaction and side effect(s): Somnolence after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Effexor treatment in female patients, resulting in Somnolence side effect.
Effexor Side Effect Report#9921625
Convulsion
This report suggests a potential Effexor Xr Convulsion side effect(s) that can have serious consequences. A 26-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: depression,anxiety,panic disorder and used Effexor Xr (dosage: Unk) starting NS. After starting Effexor Xr the patient began experiencing various side effects, including: ConvulsionAdditional drugs used concurrently: NA.The patient was hospitalized. Although Effexor Xr demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Convulsion, may still occur.
Effexor Side Effect Report#9919149
Diarrhoea, Faecal Incontinence
This Diarrhoea problem was reported by a pharmacist from US. A 63-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: anxiety. On 201401 this consumer started treatment with Effexor Xr (dosage: Unk). The following drugs were being taken at the same time: NA. When using Effexor Xr, the patient experienced the following unwanted symptoms/side effects: Diarrhoea, Faecal IncontinenceAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Diarrhoea, may become evident only after a product is in use by the general population.
Effexor Side Effect Report#9919134
Crying
This Crying side effect was reported by a consumer or non-health professional from US. A 58-year-old female patient (weight:NA) experienced the following symptoms/conditions: depression,hypertension,postoperative care.The patient was prescribed Effexor Xr (drug dosage: 75 Mg, Daily), which was initiated on NS. Concurrently used drugs:
  • Atenolol (Unk, Daily)
  • Estradiol (1 Mg, Daily)
  • Wellbutrin (300 Mg, Daily)
.After starting to take Effexor Xr the consumer reported adverse symptoms, such as: CryingThese side effects may potentially be related to Effexor Xr.
Effexor Side Effect Report#9916381
Suicidal Ideation, Bipolar I Disorder, Aggression, Anger, Imprisonment, Dizziness, Anxiety
This is a report of a 40-year-old male patient (weight: NA) from CA, suffering from the following health symptoms/conditions: depression, who was treated with Effexor (dosage: 35 Mg, 1x/day, start time: 199904), combined with: NA. and developed a serious reaction and side effect(s): Suicidal Ideation, Bipolar I Disorder, Aggression, Anger, Imprisonment, Dizziness, Anxiety after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Effexor treatment in male patients, resulting in Suicidal Ideation side effect.
Effexor Side Effect Report#9914344
Infection, Malaise, Immune System Disorder, Pyrexia, Breast Cancer Female, Large Intestine Perforation
This report suggests a potential Effexor Infection side effect(s) that can have serious consequences. A 66-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: depression,blood cholesterol increased and used Effexor (dosage: 150 Mg, Unk) starting NS. After starting Effexor the patient began experiencing various side effects, including: Infection, Malaise, Immune System Disorder, Pyrexia, Breast Cancer Female, Large Intestine PerforationAdditional drugs used concurrently:
  • Simvastatin (40 Mg, 1x/day)
The patient was hospitalized. Although Effexor demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Infection, may still occur.
Effexor Side Effect Report#9913594
Homicidal Ideation, Abnormal Behaviour, Irritability
This Homicidal Ideation problem was reported by a physician from CA. A male patient (weight: NA) was diagnosed with the following symptoms/conditions: depression. On 200410 this consumer started treatment with Effexor Xr (dosage: 37.5 Mg, Unk). The following drugs were being taken at the same time: NA. When using Effexor Xr, the patient experienced the following unwanted symptoms/side effects: Homicidal Ideation, Abnormal Behaviour, IrritabilityThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Homicidal Ideation, may become evident only after a product is in use by the general population.
Effexor Side Effect Report#9912857
Nasopharyngitis, Overdose
This Nasopharyngitis side effect was reported by a consumer or non-health professional from US. A 50-year-old female patient (weight:NA) experienced the following symptoms/conditions: depression,anxiety,blood cholesterol increased,hypertension.The patient was prescribed Effexor Xr (drug dosage: 300 Mg, Daily), which was initiated on 201306. Concurrently used drugs: NA..After starting to take Effexor Xr the consumer reported adverse symptoms, such as: Nasopharyngitis, OverdoseThese side effects may potentially be related to Effexor Xr.
Effexor Side Effect Report#9912720
Amnesia, Paraesthesia, Hypoaesthesia, Disturbance In Attention, Speech Disorder, Dysphemia, Dysphemia
This is a report of a 23-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: depression, who was treated with Effexor Xr (dosage: Taken By Mouth, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Amnesia, Paraesthesia, Hypoaesthesia, Disturbance In Attention, Speech Disorder, Dysphemia, Dysphemia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Effexor Xr treatment in female patients, resulting in Amnesia side effect.
Effexor Side Effect Report#9906681
Road Traffic Accident, Abnormal Dreams, Insomnia, Decreased Interest, Irritability, Crying, Depressed Mood
This report suggests a potential Effexor Xr Road Traffic Accident side effect(s) that can have serious consequences. A 60-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: NA and used Effexor Xr (dosage: 150 Mg, 1x/day) starting 2014. After starting Effexor Xr the patient began experiencing various side effects, including: Road Traffic Accident, Abnormal Dreams, Insomnia, Decreased Interest, Irritability, Crying, Depressed MoodAdditional drugs used concurrently:
  • Lamictal (Unk)
  • Pristiq (Unk)
  • Clonazepam (Unk)
The patient was hospitalized. Although Effexor Xr demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Road Traffic Accident, may still occur.
Effexor Side Effect Report#9906660
Suicidal Ideation, Mental Disorder, Abnormal Behaviour, Anger, Hostility, Weight Increased, Off Label Use
This Suicidal Ideation problem was reported by a consumer or non-health professional from US. A 23-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: schizophrenia. On 201310 this consumer started treatment with Effexor Xr (dosage: 150 Mg, 1x/day). The following drugs were being taken at the same time: NA. When using Effexor Xr, the patient experienced the following unwanted symptoms/side effects: Suicidal Ideation, Mental Disorder, Abnormal Behaviour, Anger, Hostility, Weight Increased, Off Label UseAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Suicidal Ideation, may become evident only after a product is in use by the general population.
Effexor Side Effect Report#9904338
Convulsion, Anaemia, Hearing Impaired, Chills, Weight Decreased, Nasopharyngitis
This Convulsion side effect was reported by a consumer or non-health professional from US. A 74-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Effexor Xr (drug dosage: 75 Mg, 1x/day), which was initiated on
Feb 11, 2014. Concurrently used drugs:
  • Metoprolol (Unk)
  • Tegretol (Unk)
  • Vitamin B12 (Unk)
.After starting to take Effexor Xr the consumer reported adverse symptoms, such as: Convulsion, Anaemia, Hearing Impaired, Chills, Weight Decreased, NasopharyngitisThese side effects may potentially be related to Effexor Xr.
Effexor Side Effect Report#9904317
Prostatic Disorder, Product Taste Abnormal, Product Physical Issue
This is a report of a 62-year-old male patient (weight: NA) from US, suffering from the following health symptoms/conditions: NA, who was treated with Effexor Xr (dosage: 150 Mg (two Capsules Of 75mg), 1x/day, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Prostatic Disorder, Product Taste Abnormal, Product Physical Issue after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Effexor Xr treatment in male patients, resulting in Prostatic Disorder side effect.
Effexor Side Effect Report#9904304
Depression, Eye Pruritus, Eyelids Pruritus, Ocular Hyperaemia, Erythema Of Eyelid
This report suggests a potential Effexor Xr Depression side effect(s) that can have serious consequences. A 74-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: major depression and used Effexor Xr (dosage: Unk) starting NS. After starting Effexor Xr the patient began experiencing various side effects, including: Depression, Eye Pruritus, Eyelids Pruritus, Ocular Hyperaemia, Erythema Of EyelidAdditional drugs used concurrently: NA. Although Effexor Xr demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Depression, may still occur.
Effexor Side Effect Report#9902675
Hyperhidrosis
This Hyperhidrosis problem was reported by a health professional from US. A 60-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Effexor (dosage: Unk). The following drugs were being taken at the same time: NA. When using Effexor, the patient experienced the following unwanted symptoms/side effects: HyperhidrosisAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Hyperhidrosis, may become evident only after a product is in use by the general population.
Effexor Side Effect Report#9901163
Pruritus, Erythema Of Eyelid
This Pruritus side effect was reported by a physician from US. A 74-year-old patient (weight:NA) experienced the following symptoms/conditions: major depression.The patient was prescribed Effexor Xr (drug dosage: 300 Mg, Unk), which was initiated on NS. Concurrently used drugs: NA..After starting to take Effexor Xr the consumer reported adverse symptoms, such as: Pruritus, Erythema Of EyelidThese side effects may potentially be related to Effexor Xr.
Effexor Side Effect Report#9901118
Anaphylactic Reaction
This is a report of a 47-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: NA, who was treated with Effexor (dosage: Unk, start time: NS), combined with:
  • Effexor Xr (Unk)
and developed a serious reaction and side effect(s): Anaphylactic Reaction after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Effexor treatment in female patients, resulting in Anaphylactic Reaction side effect.
Effexor Side Effect Report#9899645
Panic Attack, Insomnia
This report suggests a potential Effexor Panic Attack side effect(s) that can have serious consequences. A 57-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: NA and used Effexor (dosage: Unk) starting NS. After starting Effexor the patient began experiencing various side effects, including: Panic Attack, InsomniaAdditional drugs used concurrently: NA. Although Effexor demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Panic Attack, may still occur.
Effexor Side Effect Report#9898335
Atrophic Vulvovaginitis, Essential Hypertension, Hormone Level Abnormal, Menopause, Migraine, Gastrooesophageal Reflux Disease, Osteoarthritis, Insomnia, Rhinitis Allergic
This Atrophic Vulvovaginitis problem was reported by a health professional from US. A 62-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Effexor Xr (dosage: 75 Mg, Once A Day (qd)). The following drugs were being taken at the same time:
  • Zyrtec (10 Mg, Once A Day)
  • Zantac (300 Mg, Once A Day (1 Tablet))
  • Vagifem (10 Ug, Once Daily For 14 Days And Then 2 Times Per Week For Duration Of Use)
  • Tramadol (50 Mg, Every 8 Hours As Needed)
  • Mobic (7.5 Mg, Once A Day)
  • Prilosec (40 Mg, Once A Day)
  • Diovan (320 Mg, Once A Day)
  • Trazodone (50 Mg, Once A Day)
When using Effexor Xr, the patient experienced the following unwanted symptoms/side effects: Atrophic Vulvovaginitis, Essential Hypertension, Hormone Level Abnormal, Menopause, Migraine, Gastrooesophageal Reflux Disease, Osteoarthritis, Insomnia, Rhinitis AllergicAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Atrophic Vulvovaginitis, may become evident only after a product is in use by the general population.
Effexor Side Effect Report#9894364
Rash, Frustration, Bladder Pain, Urinary Tract Pain, Pain In Extremity
This Rash side effect was reported by a consumer or non-health professional from US. A 66-year-old female patient (weight:NA) experienced the following symptoms/conditions: bipolar disorder,attention deficit/hyperactivity disorder.The patient was prescribed Effexor Xr (drug dosage: Unk), which was initiated on 2014. Concurrently used drugs: NA..After starting to take Effexor Xr the consumer reported adverse symptoms, such as: Rash, Frustration, Bladder Pain, Urinary Tract Pain, Pain In ExtremityThese side effects may potentially be related to Effexor Xr. The patient was hospitalized.
Effexor Side Effect Report#9893980
Malaise, Abdominal Discomfort, Vomiting, Palpitations, Anxiety, Weight Decreased, Activities Of Daily Living Impaired, Feeling Abnormal, Nausea
This is a report of a 48-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: depression, who was treated with Effexor Xr (dosage: 37.5 Mg, Daily, start time: 201402), combined with: NA. and developed a serious reaction and side effect(s): Malaise, Abdominal Discomfort, Vomiting, Palpitations, Anxiety, Weight Decreased, Activities Of Daily Living Impaired, Feeling Abnormal, Nausea after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Effexor Xr treatment in female patients, resulting in Malaise side effect.
Effexor Side Effect Report#9888701
Headache, Dizziness, Feeling Abnormal
This report suggests a potential Effexor Headache side effect(s) that can have serious consequences. A 65-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: depression and used Effexor (dosage: Taken By Mouth) starting NS. After starting Effexor the patient began experiencing various side effects, including: Headache, Dizziness, Feeling AbnormalAdditional drugs used concurrently: NA. Although Effexor demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Headache, may still occur.
Effexor Side Effect Report#9888298
Vomiting, Headache, Weight Increased, Nausea, Dizziness, Fatigue
This Vomiting problem was reported by a consumer or non-health professional from US. A 51-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: depression. On 201401 this consumer started treatment with Effexor Xr (dosage: 75 Mg, 2x/day). The following drugs were being taken at the same time: NA. When using Effexor Xr, the patient experienced the following unwanted symptoms/side effects: Vomiting, Headache, Weight Increased, Nausea, Dizziness, FatigueAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Vomiting, may become evident only after a product is in use by the general population.
Effexor Side Effect Report#9888290
Hallucination
This Hallucination side effect was reported by a health professional from US. A 55-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Effexor Xr (drug dosage: Unk), which was initiated on NS. Concurrently used drugs: NA..After starting to take Effexor Xr the consumer reported adverse symptoms, such as: HallucinationThese side effects may potentially be related to Effexor Xr.
Effexor Side Effect Report#9885834
Hyponatraemia, Altered State Of Consciousness
This is a report of a 61-year-old female patient (weight: NA) from FR, suffering from the following health symptoms/conditions: NA, who was treated with Effexor (dosage: 75 Mg, 2x/day, start time: NS), combined with:
  • Risperdal (4 Mg, 2x/day)
  • Keppra (500 Mg, 2x/day)
  • Depakote (500 Mg, 3x/day)
  • Valium (5 Mg, Daily)
  • Levothyrox (Unk)
  • Mopral (Unk)
and developed a serious reaction and side effect(s): Hyponatraemia, Altered State Of Consciousness after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Effexor treatment in female patients, resulting in Hyponatraemia side effect. The patient was hospitalized.


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The appearance of Effexor on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

What are common Effexor Side Effects for Women?

Women Side Effects Reports
Dizziness 563
Nausea 503
Anxiety 440
Headache 382
Feeling Abnormal 374
Depression 368
Condition Aggravated 298
Suicidal Ideation 297
Malaise 288
Paraesthesia 259

What are common Effexor Side Effects for Men?

Men Side Effects Reports
Anxiety 154
Completed Suicide 148
Suicidal Ideation 145
Dizziness 137
Condition Aggravated 136
Depression 132
Feeling Abnormal 117
Paraesthesia 110
Headache 109
Insomnia 103

Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Effexor reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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    Effexor Safety Alerts, Active Ingredients, Usage Information

    NDC 0008-0833
    Type HUMAN PRESCRIPTION DRUG
    Proprietary Name Effexor XR
    Name VENLAFAXINE HYDROCHLORIDE
    Dosage Form CAPSULE, EXTENDED RELEASE
    Route ORAL
    On market since 19971101
    Labeler Wyeth Pharmaceuticals Inc., a subsidiary of Pfizer Inc.
    Active Ingredient(s) VENLAFAXINE HYDROCHLORIDE
    Strength(s) 75
    Unit(s) mg/1
    Pharma Class Norepinephrine Uptake Inhibitors [MoA],Serotonin and Norepinephrine Reuptake Inhibitor [EPC],Seroton

    Effexor Dosage, Warnings, Usage.

    Side Effects reported to FDA: 7289

    Effexor safety alerts: 2013 2006 2005 2004

    Reported deaths: 309

    Reported hospitalizations: 1358

    Latest Effexor clinical trials

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