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Endep Side Effects

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Common Endep Side Effects


The most commonly reported Endep side effects (click to view or check a box to report):

Dry Mouth (8)
Urinary Retention (3)
Dysuria (2)
Dysgeusia (2)
Anxiety (2)
Anorexia (2)
Hallucination (2)
Gingivitis (2)
Pulmonary Embolism (2)
Hyperhidrosis (2)
Oral Candidiasis (2)
Sensitivity Of Teeth (2)
Nausea (2)
Lip Dry (2)
Rash Erythematous (1)
Self-injurious Ideation (1)
Pyrexia (1)
Product Quality Issue (1)
Pollakiuria (1)
Pruritus (1)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Endep Side Effects Reported to FDA



Endep Side Effect Report#9393213
Memory Impairment, Confusional State, Speech Disorder
This is a report of a 82-year-old female patient (weight: NA) from AU, suffering from the following health symptoms/conditions: neuralgia,blood pressure, who was treated with Endep (dosage: NA, start time:
Jun 20, 2013), combined with:
  • Monoplus
  • Solian
  • Acimax
  • Aspirin
and developed a serious reaction and side effect(s): Memory Impairment, Confusional State, Speech Disorder after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Endep treatment in female patients, resulting in Memory Impairment side effect. The patient was hospitalized.
Endep Side Effect Report#8336263-X
Hypoaesthesia Oral, Rash Erythematous, Hypersensitivity, Pruritus, Oedema Mouth
This report suggests a potential Endep Hypoaesthesia Oral side effect(s) that can have serious consequences. A 63-year-old male patient (weight: NA) from Australia was diagnosed with the following symptoms/conditions: NA and used Endep (dosage: NA) starting NS. After starting Endep the patient began experiencing various side effects, including: Hypoaesthesia Oral, Rash Erythematous, Hypersensitivity, Pruritus, Oedema MouthAdditional drugs used concurrently:
  • Cartia Xt
  • Karvea
  • Zydol - Slow Release (100 Mg, As Needed)
  • Zyloprim
  • Atorvastatin Calcium (40 Mg, 1x/day)
  • Spiriva
The patient was hospitalized. Although Endep demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Hypoaesthesia Oral, may still occur.
Endep Side Effect Report#8175709-7
Cerebrovascular Accident
This Cerebrovascular Accident problem was reported by a consumer or non-health professional from Australia. A 46-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Sep 01, 2010 this consumer started treatment with Endep (dosage: Unk). The following drugs were being taken at the same time:
  • Botulinum Toxin Type A (Unk)
  • Inderal /00030001/ (Unk)
When using Endep, the patient experienced the following unwanted symptoms/side effects: Cerebrovascular AccidentAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Cerebrovascular Accident, may become evident only after a product is in use by the general population.
Endep Side Effect Report#7843065-7
Mantle Cell Lymphoma
This Mantle Cell Lymphoma side effect was reported by a health professional from Australia. A 82-year-old female patient (weight:NA) experienced the following symptoms/conditions: anxiety.The patient was prescribed Endep (drug dosage: NA), which was initiated on
Jun 04, 2010. Concurrently used drugs:
  • Panamax
  • Prolia (60 Mg, Unk)
  • Lyrica
  • Temazepam
  • Ezetimibe (10 Mg, Qd)
  • Coveram (5 Mg, Qd)
  • Dexamethasone
.After starting to take Endep the consumer reported adverse symptoms, such as: Mantle Cell LymphomaThese side effects may potentially be related to Endep. The patient was hospitalized.
Endep Side Effect Report#7636222-6
Vulval Cellulitis
This is a report of a female patient (weight: NA) from Australia, suffering from the following health symptoms/conditions: NA, who was treated with Endep (dosage: NA, start time:
Dec 13, 2010), combined with:
  • Prednisone
  • Clotrimazole
  • Estradiol
  • Golimumab
  • Temaze
  • Irbesartan + Hydrochlorothiazide
  • Spiriva
  • Rabeprazole Sodium
and developed a serious reaction and side effect(s): Vulval Cellulitis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Endep treatment in female patients, resulting in Vulval Cellulitis side effect. The patient was hospitalized.
Endep Side Effect Report#7246742-4
Product Quality Issue
This report suggests a potential Endep Product Quality Issue side effect(s) that can have serious consequences. A 58-year-old male patient (weight: NA) from Australia was diagnosed with the following symptoms/conditions: NA and used Endep (dosage: NA) starting NS. After starting Endep the patient began experiencing various side effects, including: Product Quality IssueAdditional drugs used concurrently:
  • Mobic
  • Duragesic-100
  • Zoloft
  • Duragesic-100
  • Emadine Se
  • Xanax
Although Endep demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Product Quality Issue, may still occur.
Endep Side Effect Report#6659527-4
Iiird Nerve Paralysis
This Iiird Nerve Paralysis problem was reported by a physician from Australia. A 76-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: post herpetic neuralgia. On
Mar 03, 2009 this consumer started treatment with Endep (dosage: NA). The following drugs were being taken at the same time:
  • Lyrica
  • Lyrica
  • Prednisolone
When using Endep, the patient experienced the following unwanted symptoms/side effects: Iiird Nerve ParalysisThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Iiird Nerve Paralysis, may become evident only after a product is in use by the general population.
Endep Side Effect Report#6347734-X
Breast Cancer, Chest Pain, Palpitations, Pulmonary Embolism, Tremor
This Breast Cancer side effect was reported by a consumer or non-health professional from Australia. A 49-year-old female patient (weight:NA) experienced the following symptoms/conditions: pain.The patient was prescribed Endep (drug dosage: NA), which was initiated on
Feb 23, 2009. Concurrently used drugs: NA..After starting to take Endep the consumer reported adverse symptoms, such as: Breast Cancer, Chest Pain, Palpitations, Pulmonary Embolism, TremorThese side effects may potentially be related to Endep. The patient was hospitalized.
Endep Side Effect Report#6125957-2
Pulmonary Embolism
This is a report of a 49-year-old female patient (weight: NA) from Australia, suffering from the following health symptoms/conditions: pain, who was treated with Endep (dosage: 10 Mg;daily; Oral, start time:
Feb 23, 2009), combined with: NA. and developed a serious reaction and side effect(s): Pulmonary Embolism after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Endep treatment in female patients, resulting in Pulmonary Embolism side effect. The patient was hospitalized.
Endep Side Effect Report#6112267-2
Feeling Hot, Nausea, Syncope
This report suggests a potential Endep Feeling Hot side effect(s) that can have serious consequences. A 64-year-old female patient (weight: NA) from Australia was diagnosed with the following symptoms/conditions: depression and used Endep (dosage: 25 Mg, Daily, Oral) starting
Jan 01, 2002. After starting Endep the patient began experiencing various side effects, including: Feeling Hot, Nausea, SyncopeAdditional drugs used concurrently:
  • Zomig
Although Endep demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Feeling Hot, may still occur.
Endep Side Effect Report#6012622-5
Depression
This Depression problem was reported by a consumer or non-health professional from Australia. A 73-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: anxiety. On
Nov 25, 2008 this consumer started treatment with Endep (dosage: 5 Mg;at Bedtime; Oral). The following drugs were being taken at the same time:
  • Xanax
  • Cardizem
  • Nexium
When using Endep, the patient experienced the following unwanted symptoms/side effects: DepressionAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Depression, may become evident only after a product is in use by the general population.
Endep Side Effect Report#5920419-7
Open Angle Glaucoma
This Open Angle Glaucoma side effect was reported by a consumer or non-health professional from Australia. A 53-year-old female patient (weight:NA) experienced the following symptoms/conditions: insomnia,tension headache.The patient was prescribed Endep (drug dosage: 50 Mg;at Bedtime; Oral), which was initiated on
Jan 01, 1990. Concurrently used drugs: NA..After starting to take Endep the consumer reported adverse symptoms, such as: Open Angle GlaucomaThese side effects may potentially be related to Endep.
Endep Side Effect Report#5844603-6
Abnormal Sleep-related Event, Dry Mouth, Gingivitis, Oral Candidiasis, Pollakiuria, Sensitivity Of Teeth, Urinary Retention
This is a report of a 43-year-old female patient (weight: NA) from Australia, suffering from the following health symptoms/conditions: neuralgia, who was treated with Endep (dosage: 150 Mg; At Bedtime; Oral, 125 Mg; At Bedtime; Oral, 100 Mg; At Bedtime; Oral, start time:
Jul 23, 2008), combined with: NA. and developed a serious reaction and side effect(s): Abnormal Sleep-related Event, Dry Mouth, Gingivitis, Oral Candidiasis, Pollakiuria, Sensitivity Of Teeth, Urinary Retention after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Endep treatment in female patients, resulting in Abnormal Sleep-related Event side effect.
Endep Side Effect Report#5811075-7
Dry Mouth, Dysgeusia, Hallucination, Hyperhidrosis, Illusion, Lip Dry
This report suggests a potential Endep Dry Mouth side effect(s) that can have serious consequences. A 69-year-old female patient (weight: NA) from Australia was diagnosed with the following symptoms/conditions: anxiety and used Endep (dosage: 50 Mg; At Bedtime; Oral) starting
Jan 01, 2007. After starting Endep the patient began experiencing various side effects, including: Dry Mouth, Dysgeusia, Hallucination, Hyperhidrosis, Illusion, Lip DryAdditional drugs used concurrently:
  • Protos(con.)
  • Brufen /00109201/ (con.)
  • Rani (con.)
  • Aratac (con.)
  • Avapro (con.)
  • Warfarin (con.)
  • Zocor (con.)
Although Endep demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Dry Mouth, may still occur.
Endep Side Effect Report#5754127-2
Bladder Disorder, Dry Mouth, Dysuria, Gingivitis, Oral Candidiasis, Sensitivity Of Teeth, Sleep Disorder, Urinary Retention
This Bladder Disorder problem was reported by a consumer or non-health professional from Australia. A 43-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: neuralgia. On
Dec 01, 2005 this consumer started treatment with Endep (dosage: 150 Mg; At Bedtime; Oral). The following drugs were being taken at the same time:
  • Trifeme
  • Lyrica
  • Neurontin
  • Ditropan
  • Panadeine
  • Vesicare
  • Coloxyl With Senna
  • Avanza
When using Endep, the patient experienced the following unwanted symptoms/side effects: Bladder Disorder, Dry Mouth, Dysuria, Gingivitis, Oral Candidiasis, Sensitivity Of Teeth, Sleep Disorder, Urinary RetentionAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Bladder Disorder, may become evident only after a product is in use by the general population.
Endep Side Effect Report#5753052-0
Condition Aggravated, Dry Mouth, Dysgeusia, Hallucination, Hyperhidrosis, Lip Dry
This Condition Aggravated side effect was reported by a consumer or non-health professional from Australia. A 69-year-old female patient (weight:NA) experienced the following symptoms/conditions: anxiety.The patient was prescribed Endep (drug dosage: 50 Mg; At Bedtime; Oral), which was initiated on
Jan 01, 2007. Concurrently used drugs:
  • Protos
  • Brufen
  • Rani
  • Aratac
  • Avapro
  • Warfarin Sodium
  • Zocor
.After starting to take Endep the consumer reported adverse symptoms, such as: Condition Aggravated, Dry Mouth, Dysgeusia, Hallucination, Hyperhidrosis, Lip DryThese side effects may potentially be related to Endep.
Endep Side Effect Report#5725069-3
Anorexia, Chills, Dry Mouth, Gait Disturbance, Influenza, Myalgia, Nausea, Pharyngolaryngeal Pain, Pyrexia
This is a report of a 64-year-old male patient (weight: NA) from Australia, suffering from the following health symptoms/conditions: depression, who was treated with Endep (dosage: 50 Mg; Daily; Oral, start time:
Apr 04, 2008), combined with:
  • Metformin Hcl
  • Prednisone Tab
  • Zocor
  • Pantoprazole Sodium
  • Myocrisin
and developed a serious reaction and side effect(s): Anorexia, Chills, Dry Mouth, Gait Disturbance, Influenza, Myalgia, Nausea, Pharyngolaryngeal Pain, Pyrexia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Endep treatment in male patients, resulting in Anorexia side effect.
Endep Side Effect Report#5706342-1
Abnormal Behaviour, Anorexia, Anxiety, Convulsion, Mood Altered, Spousal Abuse, Stress, Suicidal Ideation
This report suggests a potential Endep Abnormal Behaviour side effect(s) that can have serious consequences. A 29-year-old female patient (weight: NA) from Australia was diagnosed with the following symptoms/conditions: depression and used Endep (dosage: Oral) starting
Feb 08, 2008. After starting Endep the patient began experiencing various side effects, including: Abnormal Behaviour, Anorexia, Anxiety, Convulsion, Mood Altered, Spousal Abuse, Stress, Suicidal IdeationAdditional drugs used concurrently:
  • Tramadol Hcl (Oral)
  • Restavit
  • Digesic
Although Endep demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Abnormal Behaviour, may still occur.
Endep Side Effect Report#5694191-2
Blood Electrolytes Abnormal, Dizziness, Fall, Somnolence, Transient Ischaemic Attack, Upper Limb Fracture
This Blood Electrolytes Abnormal problem was reported by a physician from Australia. A 76-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: depression. On
Jan 01, 2008 this consumer started treatment with Endep (amitriptyline Hydrochloride) (50 Mg) (dosage: 50 Mg;at Bedtime;oral). The following drugs were being taken at the same time: NA. When using Endep (amitriptyline Hydrochloride) (50 Mg), the patient experienced the following unwanted symptoms/side effects: Blood Electrolytes Abnormal, Dizziness, Fall, Somnolence, Transient Ischaemic Attack, Upper Limb FractureThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Blood Electrolytes Abnormal, may become evident only after a product is in use by the general population.
Endep Side Effect Report#5670150-0
Dry Mouth, Dysuria, Eye Pain, Hallucination, Auditory, Insomnia, Paraesthesia, Sensation Of Heaviness
This Dry Mouth side effect was reported by a consumer or non-health professional from Australia. A 55-year-old female patient (weight:NA) experienced the following symptoms/conditions: depression.The patient was prescribed Endep (drug dosage: 20 Mg; At Bedtime; Oral), which was initiated on
Jan 01, 2006. Concurrently used drugs:
  • Lipitor
  • Ural
.After starting to take Endep the consumer reported adverse symptoms, such as: Dry Mouth, Dysuria, Eye Pain, Hallucination, Auditory, Insomnia, Paraesthesia, Sensation Of HeavinessThese side effects may potentially be related to Endep.
Endep Side Effect Report#5614060-3
Dry Mouth, Tardive Dyskinesia, Trismus, Vision Blurred
This is a report of a 75-year-old female patient (weight: NA) from Australia, suffering from the following health symptoms/conditions: fibromyalgia, who was treated with Endep (dosage: 25 Mg;nocte;oral, start time:
Jan 01, 2002), combined with: NA. and developed a serious reaction and side effect(s): Dry Mouth, Tardive Dyskinesia, Trismus, Vision Blurred after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Endep treatment in female patients, resulting in Dry Mouth side effect.
Endep Side Effect Report#5503568-7
Agitation, Anxiety, Delusion, Nightmare, Paranoia, Urinary Retention
This report suggests a potential Endep Agitation side effect(s) that can have serious consequences. A 33-year-old male patient (weight: NA) from United States was diagnosed with the following symptoms/conditions: bone pain,neuralgia and used Endep (dosage: 50 Mg; Hd; Oral; 10 Mg; Hd; Oral) starting
Oct 17, 2007. After starting Endep the patient began experiencing various side effects, including: Agitation, Anxiety, Delusion, Nightmare, Paranoia, Urinary RetentionAdditional drugs used concurrently: NA. Although Endep demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Agitation, may still occur.
Endep Side Effect Report#5500099-5
Aggression, Dry Mouth, Fatigue, Self-injurious Ideation, Tearfulness
This Aggression problem was reported by a consumer or non-health professional from . A 57-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: burning sensation. On
Oct 04, 2007 this consumer started treatment with Endep (amitriptyline Hydrochloride) (25 Mg) (dosage: 25 Mg). The following drugs were being taken at the same time: NA. When using Endep (amitriptyline Hydrochloride) (25 Mg), the patient experienced the following unwanted symptoms/side effects: Aggression, Dry Mouth, Fatigue, Self-injurious Ideation, TearfulnessAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Aggression, may become evident only after a product is in use by the general population.



The appearance of Endep on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

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What are common Endep Side Effects for Women?

Women Side EffectsReports
Dry Mouth 7
Dysgeusia 2
Dysuria 2
Gingivitis 2
Hallucination 2
Hyperhidrosis 2
Lip Dry 2
Oral Candidiasis 2
Pulmonary Embolism 2
Sensitivity Of Teeth 2

What are common Endep Side Effects for Men?

Men Side EffectsReports
Agitation 1
Anorexia 1
Anxiety 1
Chills 1
Delusion 1
Dry Mouth 1
Gait Disturbance 1
Hypersensitivity 1
Hypoaesthesia Oral 1
Influenza 1

Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Endep reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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    Discuss Endep Side Effects

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