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Endoxan Side Effects

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Common Endoxan Side Effects


The most commonly reported Endoxan side effects (click to view or check a box to report):

Pyrexia (145)
Febrile Neutropenia (124)
Neutropenia (94)
Pneumonia (90)
Pancytopenia (68)
Sepsis (66)
Dyspnoea (62)
Anaemia (57)
Diarrhoea (56)
Vomiting (55)
Nausea (49)
Interstitial Lung Disease (48)
Septic Shock (44)
Respiratory Failure (44)
Thrombocytopenia (44)
Pulmonary Embolism (43)
Death (43)
Headache (39)
Cardiac Failure (39)
Cough (38)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Endoxan Side Effects Reported to FDA



Endoxan Side Effect Report#9994130
No Therapeutic Response
This is a report of a 31-year-old female patient (weight: NA) from DE, suffering from the following health symptoms/conditions: complication of pregnancy, who was treated with Endoxan 1g (dosage: NA, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): No Therapeutic Response after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Endoxan 1g treatment in female patients, resulting in No Therapeutic Response side effect.
Endoxan Side Effect Report#9975729
Infected Skin Ulcer, Pancytopenia, Cytomegalovirus Infection
This report suggests a potential Endoxan Infected Skin Ulcer side effect(s) that can have serious consequences. A 64-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: microscopic polyangiitis and used Endoxan (dosage: NA) starting NS. After starting Endoxan the patient began experiencing various side effects, including: Infected Skin Ulcer, Pancytopenia, Cytomegalovirus InfectionAdditional drugs used concurrently:
  • Prednisone
  • Prednisone
  • Rituximab
  • Azathioprine
Although Endoxan demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Infected Skin Ulcer, may still occur.
Endoxan Side Effect Report#9975187
Failure To Thrive
This Failure To Thrive problem was reported by a health professional from JP. A 22-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Endoxan (dosage: NA). The following drugs were being taken at the same time: NA. When using Endoxan, the patient experienced the following unwanted symptoms/side effects: Failure To ThriveAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Failure To Thrive, may become evident only after a product is in use by the general population.
Endoxan Side Effect Report#9928933
Exposure During Pregnancy
This Exposure During Pregnancy side effect was reported by a pharmacist from DE. A 29-year-old female patient (weight:NA) experienced the following symptoms/conditions: breast cancer.The patient was prescribed Endoxan 1g (drug dosage: NA), which was initiated on
Feb 10, 2014. Concurrently used drugs: NA..After starting to take Endoxan 1g the consumer reported adverse symptoms, such as: Exposure During PregnancyThese side effects may potentially be related to Endoxan 1g.
Endoxan Side Effect Report#9926241
Vasculitis
This is a report of a 66-year-old male patient (weight: NA) from RS, suffering from the following health symptoms/conditions: sjogren^s syndrome,systemic sclerosis, who was treated with Endoxan 1 G (dosage: NA, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Vasculitis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Endoxan 1 G treatment in male patients, resulting in Vasculitis side effect. The patient was hospitalized.
Endoxan Side Effect Report#9912034
Febrile Bone Marrow Aplasia, Ileus Paralytic, Tendon Pain, Colitis
This report suggests a potential Endoxan 2000 Mg, Lyophilisat Pour Solution Injectable Febrile Bone Marrow Aplasia side effect(s) that can have serious consequences. A 39-year-old male patient (weight: NA) from FR was diagnosed with the following symptoms/conditions: burkitt^s lymphoma and used Endoxan 2000 Mg, Lyophilisat Pour Solution Injectable (dosage: NA) starting
Jul 24, 2012. After starting Endoxan 2000 Mg, Lyophilisat Pour Solution Injectable the patient began experiencing various side effects, including: Febrile Bone Marrow Aplasia, Ileus Paralytic, Tendon Pain, ColitisAdditional drugs used concurrently:
  • Vincristine Sulfate
  • Mabthera
  • Doxorubicine Hydrochloride
  • Dexamethasone
  • Aracytine
  • Truvada
  • Truvada
  • Isentress
Although Endoxan 2000 Mg, Lyophilisat Pour Solution Injectable demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Febrile Bone Marrow Aplasia, may still occur.
Endoxan Side Effect Report#9910427
Bronchial Carcinoma
This Bronchial Carcinoma problem was reported by a physician from DE. A 63-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: granuloma. On NS this consumer started treatment with Endoxan 1g (dosage: NA). The following drugs were being taken at the same time: NA. When using Endoxan 1g, the patient experienced the following unwanted symptoms/side effects: Bronchial CarcinomaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Bronchial Carcinoma, may become evident only after a product is in use by the general population.
Endoxan Side Effect Report#9907490
Serositis, Glaucoma, Osteoporosis
This Serositis side effect was reported by a physician from JP. A 14-year-old female patient (weight:NA) experienced the following symptoms/conditions: systemic lupus erythematosus.The patient was prescribed Endoxan 1g (drug dosage: NA), which was initiated on 201302. Concurrently used drugs:
  • Predonine
  • Azanin
  • Selbex
  • Bonoteo
  • Domperidone
  • Alfarol
  • Granisetron
  • Methylprednisolone
.After starting to take Endoxan 1g the consumer reported adverse symptoms, such as: Serositis, Glaucoma, OsteoporosisThese side effects may potentially be related to Endoxan 1g. The patient was hospitalized.
Endoxan Side Effect Report#9903655
Breast Cancer Recurrent, Bone Neoplasm
This is a report of a 64-year-old female patient (weight: NA) from PL, suffering from the following health symptoms/conditions: breast cancer, who was treated with Endoxan (dosage: NA, start time: 1997), combined with:
  • Methotrexate
  • Fluorouracil
  • Bisoprolol
  • Vinpocetine
  • Sertraline
and developed a serious reaction and side effect(s): Breast Cancer Recurrent, Bone Neoplasm after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Endoxan treatment in female patients, resulting in Breast Cancer Recurrent side effect.
Endoxan Side Effect Report#9903064
Gastrointestinal Obstruction
This report suggests a potential Endoxan Gastrointestinal Obstruction side effect(s) that can have serious consequences. A 64-year-old female patient (weight: NA) from PL was diagnosed with the following symptoms/conditions: breast cancer recurrent and used Endoxan (dosage: NA) starting 201302. After starting Endoxan the patient began experiencing various side effects, including: Gastrointestinal ObstructionAdditional drugs used concurrently:
  • Doxorubicin
  • Bisoprolol
  • Vinpocetine
  • Sertraline
The patient was hospitalized. Although Endoxan demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Gastrointestinal Obstruction, may still occur.
Endoxan Side Effect Report#9899419
Pneumonia
This Pneumonia problem was reported by a health professional from FR. A 63-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On 201311 this consumer started treatment with Endoxan 50 Mg, Comprim? Enrob? (dosage: NA). The following drugs were being taken at the same time: NA. When using Endoxan 50 Mg, Comprim? Enrob?, the patient experienced the following unwanted symptoms/side effects: PneumoniaThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Pneumonia, may become evident only after a product is in use by the general population.
Endoxan Side Effect Report#9894798
Hypokalaemia, Pancytopenia, Vomiting, Diarrhoea
This Hypokalaemia side effect was reported by a health professional from FR. A 50-year-old female patient (weight:NA) experienced the following symptoms/conditions: b-cell lymphoma.The patient was prescribed Endoxan 2000 Mg, Lyophilisat Pour Solution Injectable (drug dosage: NA), which was initiated on
Dec 06, 2013. Concurrently used drugs: NA..After starting to take Endoxan 2000 Mg, Lyophilisat Pour Solution Injectable the consumer reported adverse symptoms, such as: Hypokalaemia, Pancytopenia, Vomiting, DiarrhoeaThese side effects may potentially be related to Endoxan 2000 Mg, Lyophilisat Pour Solution Injectable. The patient was hospitalized.
Endoxan Side Effect Report#9892681
Diplopia
This is a report of a 15-year-old male patient (weight: NA) from PL, suffering from the following health symptoms/conditions: lymphoma, who was treated with Endoxan (dosage: NA, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Diplopia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Endoxan treatment in male patients, resulting in Diplopia side effect.
Endoxan Side Effect Report#9886749
Kaposi^s Sarcoma, Sepsis
This report suggests a potential Endoxan 2000 Mg, Lyophilisat Pour Solution Injectable Kaposi^s Sarcoma side effect(s) that can have serious consequences. A 69-year-old female patient (weight: NA) from FR was diagnosed with the following symptoms/conditions: plasma cell myeloma and used Endoxan 2000 Mg, Lyophilisat Pour Solution Injectable (dosage: NA) starting
Mar 08, 2013. After starting Endoxan 2000 Mg, Lyophilisat Pour Solution Injectable the patient began experiencing various side effects, including: Kaposi^s Sarcoma, SepsisAdditional drugs used concurrently: NA.The patient was hospitalized. Although Endoxan 2000 Mg, Lyophilisat Pour Solution Injectable demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Kaposi^s Sarcoma, may still occur.
Endoxan Side Effect Report#9879790
Kaposi^s Sarcoma
This Kaposi^s Sarcoma problem was reported by a health professional from FR. A 63-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: amyloidosis. On
Aug 05, 2013 this consumer started treatment with Endoxan 50 Mg, Comprim? Enrob? (dosage: NA). The following drugs were being taken at the same time:
  • Velcade
  • Dexamethasone
  • Januvia
  • Lipanthyl
  • Gaviscon
  • Bactrim
  • Phenoxymethylpenicillin
  • Zelitrex
When using Endoxan 50 Mg, Comprim? Enrob?, the patient experienced the following unwanted symptoms/side effects: Kaposi^s SarcomaThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Kaposi^s Sarcoma, may become evident only after a product is in use by the general population.
Endoxan Side Effect Report#9878136
Supraventricular Tachycardia, Tinnitus, Condition Aggravated
This Supraventricular Tachycardia side effect was reported by a health professional from FR. A 58-year-old male patient (weight:NA) experienced the following symptoms/conditions: waldenstrom^s macroglobulinaemia.The patient was prescribed Endoxan 50 Mg, Comprim? Enrob? (drug dosage: NA), which was initiated on
Oct 28, 2013. Concurrently used drugs: NA..After starting to take Endoxan 50 Mg, Comprim? Enrob? the consumer reported adverse symptoms, such as: Supraventricular Tachycardia, Tinnitus, Condition AggravatedThese side effects may potentially be related to Endoxan 50 Mg, Comprim? Enrob?.
Endoxan Side Effect Report#9858799
Pneumonia, Non-hodgkin^s Lymphoma
This is a report of a 64-year-old female patient (weight: NA) from IT, suffering from the following health symptoms/conditions: non-hodgkin^s lymphoma, who was treated with Endoxan Baxter (dosage: NA, start time:
Nov 21, 2013), combined with:
  • Myocet
  • Mabthera
  • Deltacortene
  • Vincristina Solfato
and developed a serious reaction and side effect(s): Pneumonia, Non-hodgkin^s Lymphoma after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Endoxan Baxter treatment in female patients, resulting in Pneumonia side effect. The patient was hospitalized.
Endoxan Side Effect Report#9851109
Diabetes Mellitus, Oral Candidiasis, Leukopenia, Deep Vein Thrombosis
This report suggests a potential Endoxan Baxter Diabetes Mellitus side effect(s) that can have serious consequences. A 73-year-old male patient (weight: NA) from IT was diagnosed with the following symptoms/conditions: antineutrophil cytoplasmic antibody positive,pulse abnormal and used Endoxan Baxter (dosage: NA) starting NS. After starting Endoxan Baxter the patient began experiencing various side effects, including: Diabetes Mellitus, Oral Candidiasis, Leukopenia, Deep Vein ThrombosisAdditional drugs used concurrently:
  • Methylprednisolone
  • Prednisone
  • Prednisone
  • Rituximab
  • 5% Platelet Lysate
Although Endoxan Baxter demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Diabetes Mellitus, may still occur.
Endoxan Side Effect Report#9850697
Progressive Multifocal Leukoencephalopathy, Jc Virus Infection
This Progressive Multifocal Leukoencephalopathy problem was reported by a health professional from NL. A 74-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: diffuse large b-cell lymphoma. On NS this consumer started treatment with Endoxan I.v., Poeder Voor Oplossing Voor Injectie 200, 500, 1000 Mg (dosage: 6 Total Doses). The following drugs were being taken at the same time:
  • Doxorubicin (6 Total Doses)
  • Vincristine (6 Total Doses)
  • Prednisolone (6 Total Doses)
  • Rituximab (6 Total Doses)
  • Rituximab (3 Cycles)
  • Granulocyte Colony-stimulating Factor
When using Endoxan I.v., Poeder Voor Oplossing Voor Injectie 200, 500, 1000 Mg, the patient experienced the following unwanted symptoms/side effects: Progressive Multifocal Leukoencephalopathy, Jc Virus InfectionAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Progressive Multifocal Leukoencephalopathy, may become evident only after a product is in use by the general population.
Endoxan Side Effect Report#9850333
Haemolysis, Hepatic Enzyme Increased
This Haemolysis side effect was reported by a physician from CH. A 60-year-old male patient (weight:NA) experienced the following symptoms/conditions: bone marrow conditioning regimen,prophylaxis.The patient was prescribed Endoxan 1 G (drug dosage: NA), which was initiated on
Dec 01, 2013. Concurrently used drugs:
  • Uromitexan Multidose 100 Mg/1 Ml
  • Uromitexan Multidose 100 Mg/1 Ml
  • Uromitexan Multidose 100 Mg/1 Ml
  • Busulfan
  • Busulfan
  • Atg Fresenius
  • Atg Fresenius
  • Metotrexate
.After starting to take Endoxan 1 G the consumer reported adverse symptoms, such as: Haemolysis, Hepatic Enzyme IncreasedThese side effects may potentially be related to Endoxan 1 G. The patient was hospitalized.
Endoxan Side Effect Report#9843121
Intestinal Obstruction
This is a report of a 65-year-old female patient (weight: NA) from JP, suffering from the following health symptoms/conditions: scleroderma, who was treated with Endoxan 1g (dosage: NA, start time: 201311), combined with:
  • Predonine
and developed a serious reaction and side effect(s): Intestinal Obstruction after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Endoxan 1g treatment in female patients, resulting in Intestinal Obstruction side effect.
Endoxan Side Effect Report#9834727
Biliary Tract Disorder, Hepatic Encephalopathy, Pneumonia
This report suggests a potential Endoxan 2000 Mg, Lyophilisat Pour Solution Injectable Biliary Tract Disorder side effect(s) that can have serious consequences. A 57-year-old male patient (weight: NA) from FR was diagnosed with the following symptoms/conditions: vasculitis and used Endoxan 2000 Mg, Lyophilisat Pour Solution Injectable (dosage: 400 Mg/m2) starting 201306. After starting Endoxan 2000 Mg, Lyophilisat Pour Solution Injectable the patient began experiencing various side effects, including: Biliary Tract Disorder, Hepatic Encephalopathy, PneumoniaAdditional drugs used concurrently:
  • Solupred
  • Solupred
  • Fortum
  • Ciflox
Although Endoxan 2000 Mg, Lyophilisat Pour Solution Injectable demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Biliary Tract Disorder, may still occur.
Endoxan Side Effect Report#9833091
Aortic Valve Incompetence
This Aortic Valve Incompetence problem was reported by a health professional from TR. A 19-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: takayasu^s arteritis. On NS this consumer started treatment with Endoxan 1g. Iv (dosage: NA). The following drugs were being taken at the same time:
  • Prednisolone
  • Dipyridamole
When using Endoxan 1g. Iv, the patient experienced the following unwanted symptoms/side effects: Aortic Valve IncompetenceAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Aortic Valve Incompetence, may become evident only after a product is in use by the general population.
Endoxan Side Effect Report#9833077
Campylobacter Sepsis, Leukopenia, C-reactive Protein Increased, Pulmonary Embolism
This Campylobacter Sepsis side effect was reported by a physician from PL. A 44-year-old male patient (weight:NA) experienced the following symptoms/conditions: lymphoma.The patient was prescribed Endoxan (drug dosage: NA), which was initiated on NS. Concurrently used drugs:
  • Rituximab
  • Doxorubicin
  • Vincristine
  • Prednisone
.After starting to take Endoxan the consumer reported adverse symptoms, such as: Campylobacter Sepsis, Leukopenia, C-reactive Protein Increased, Pulmonary EmbolismThese side effects may potentially be related to Endoxan. The patient was hospitalized.
Endoxan Side Effect Report#9830800
Retinal Haemorrhage, Hypoaesthesia
This is a report of a 48-year-old female patient (weight: NA) from FR, suffering from the following health symptoms/conditions: breast cancer, who was treated with Endoxan 2000 Mg, Lyophilisat Pour Solution Injectable (dosage: NA, start time: 201302), combined with:
  • Xgeva
and developed a serious reaction and side effect(s): Retinal Haemorrhage, Hypoaesthesia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Endoxan 2000 Mg, Lyophilisat Pour Solution Injectable treatment in female patients, resulting in Retinal Haemorrhage side effect.


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The appearance of Endoxan on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.


What are common Endoxan Side Effects for Women?

Women Side EffectsReports
Pyrexia 75
Febrile Neutropenia 72
Neutropenia 52
Vomiting 46
Dyspnoea 45
Pancytopenia 43
Nausea 38
Pneumonia 38
Diarrhoea 37
Sepsis 33

What are common Endoxan Side Effects for Men?

Men Side EffectsReports
Pyrexia 70
Febrile Neutropenia 51
Pneumonia 51
Neutropenia 42
Sepsis 31
Interstitial Lung Disease 30
Respiratory Failure 29
Death 27
Pancytopenia 24
Anaemia 22

Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Endoxan reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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    Endoxan Safety Alerts, Active Ingredients, Usage Information

    More About Endoxan

    Side Effects reported to FDA: 1890

    Endoxan safety alerts: No

    Reported deaths: 165

    Reported hospitalizations: 448

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