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Enzymes Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Appendicitis Perforated (7989180-9)
on Dec 06, 2011 Male from CANADA , weighting 132.9 lb, was treated with Enzymes. Directly after, patient experienced the unwanted or unexpected Enzymes side effects: appendicitis perforated. Enzymes dosage: N/A.
Associated medications used:
  • Remicade (The Patient Was Off Infliximab From 13-jul-2011 To 06-dec-2011)
  • Remicade (The Patient Was Off Infliximab From 13-jul-2011 To 06-dec-2011)
Patient was hospitalized.

Flatulence, Dyspnoea, Dizziness, Gastrointestinal Pain, Abdominal Discomfort (7451261-6)
Patient was taking Enzymes. Patient felt the following Enzymes side effects: flatulence, dyspnoea, dizziness, gastrointestinal pain, abdominal discomfort on Apr 11, 2011 from UNITED STATES Additional patient health information: Female , 46 years of age, weighting 115.1 lb, . Enzymes dosage: N/A.
Multiple prescriptions taken:
  • Probiotics
  • Amitiza (24 Mcg, Bid, Oral; 24 Mcg, Qd, Oral; 8 Mcg, Bid, Oral)
  • Amitiza (24 Mcg, Bid, Oral; 24 Mcg, Qd, Oral; 8 Mcg, Bid, Oral)
  • Amitiza (24 Mcg, Bid, Oral; 24 Mcg, Qd, Oral; 8 Mcg, Bid, Oral)
  • Amitiza (24 Mcg, Bid, Oral; 24 Mcg, Qd, Oral; 8 Mcg, Bid, Oral)
  • Amitiza (24 Mcg, Bid, Oral; 24 Mcg, Qd, Oral; 8 Mcg, Bid, Oral)
  • Amitiza (24 Mcg, Bid, Oral; 24 Mcg, Qd, Oral; 8 Mcg, Bid, Oral)


Arthralgia, Cardiac Flutter, Joint Swelling (7395262-5)
Adverse event was reported on Mar 31, 2011 by a Female taking Enzymes (Dosage: N/A) . Location: UNITED STATES , weighting 125.2 lb, After Enzymes was administered, patient encountered several Enzymes side effects: arthralgia, cardiac flutter, joint swelling.
Multiple concurrent drugs taken:
  • Claritin
  • Prelief
  • Vagifem
  • Levaquin (750mg Daily For Oral 5 Days)
  • Aleve


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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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