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Tremor (4)
Tremors (4)
Dry Mouth (3)
Yeast Infection (3)
Joint Pain Muscle Pain (2)
UTI (2)
Excessive Sweating- Loss Of Appetite- Headaches-vo (1)
>>View All User Submitted Estrace Side Effects

Estrace Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 469 

Urinary Tract Infection (8133783-8)
on Feb 13, 2012 Female from UNITED STATES , 85 years of age, weighting 150.0 lb, was diagnosed with
  • prophylaxis urinary tract infection
and was treated with Estrace. Directly after, patient experienced the unwanted or unexpected Estrace side effects: urinary tract infection. Estrace dosage: Apply 1 Figer Tipfull.
Associated medications used:
  • Coumadin
  • Ramipril
  • Zocor
  • Zetia


Asthma, Spinal Column Stenosis, Hypersensitivity, Body Height Decreased (8125612-3)
Patient was taking Estrace. Patient felt the following Estrace side effects: asthma, spinal column stenosis, hypersensitivity, body height decreased on Feb 03, 2012 from UNITED STATES Additional patient health information: Female , weighting 179.0 lb, was diagnosed with
  • hormone level abnormal
  • balance disorder
  • hypertension
and. Estrace dosage: Unk.
Multiple prescriptions taken:
  • Antivert (25 Mg, As Needed)
  • Dilacor Xr (Unk)
  • Dyazide (Unk)
  • Antivert


Hyperlipidaemia, Renal Artery Stenosis, Deafness, Blood Cholesterol Increased, Type 2 Diabetes Mellitus, Rhinitis Allergic, Fall, Impaired Healing, Decreased Appetite (8076863-8)
Adverse event was reported on Jan 17, 2012 by a Female taking Estrace (Dosage: N/A) was diagnosed with
  • menopause
and. Location: UNITED STATES , 51 years of age, weighting 185.2 lb, After Estrace was administered, patient encountered several Estrace side effects: hyperlipidaemia, renal artery stenosis, deafness, blood cholesterol increased, type 2 diabetes mellitus, rhinitis allergic, fall, impaired healing, decreased appetite.
Multiple concurrent drugs taken:
  • Alendronate Sodium
  • Fosamax
  • Fosamax
  • Fosamax
  • Fosamax
  • Multi Vite
  • Benicar
  • Fosamax
Patient was hospitalized and became disabled.

Influenza Like Illness, Pain (8068169-8)
on Aug 31, 2011 Female from UNITED STATES , 77 years of age, weighting 161.0 lb, was treated with Estrace. Directly after, patient experienced the unwanted or unexpected Estrace side effects: influenza like illness, pain. Estrace dosage: N/A.
Associated medications used:
  • Omeprazole
  • Aciphex
  • Lexapro
  • Prolia (60 Mg, Q6mo)
  • Butalbital
  • Advicor



Hyperlipidaemia, Hormone Level Abnormal, Anxiety, Decreased Appetite, Vitamin D Deficiency, Rhinitis Allergic, Eczema, Blood Pressure Increased, Fall (8042678-X)
on Jan 10, 2012 Female from UNITED STATES , 50 years of age, weighting 185.2 lb, was diagnosed with
  • menopause
and was treated with Estrace. Patient felt the following Estrace side effects: hyperlipidaemia, hormone level abnormal, anxiety, decreased appetite, vitamin d deficiency, rhinitis allergic, eczema, blood pressure increased, fall. Estrace dosage: N/A.
Multiple prescriptions taken:
  • Alendronate Sodium
  • Fosamax
  • Alendronate Sodium
  • Fosamax
  • Vita C
  • Alendronate Sodium
  • Fosamax
  • Benicar
Patient was hospitalized and became disabled.

Breast Cancer Female (8017805-0)
Patient was taking Estrace. After Estrace was administered, patient encountered several Estrace side effects: breast cancer female on Dec 27, 2011 from UNITED STATES Additional patient health information: Female , weighting 134.5 lb, was diagnosed with
  • menopausal symptoms
and. Estrace dosage: N/A.
Multiple concurrent drugs taken:
  • Activella
  • Estradiol (1 Mg, Unk)
  • Prempro (0.625/2.5mg)
  • Provera


Psychological Trauma, Hysterectomy, Pain, Abdominal Pain Upper, Cholecystectomy, Sexual Dysfunction, Emotional Distress, Anxiety, Cholecystitis Acute (7998596-6)
Adverse event was reported on Dec 12, 2011 by a Female taking Estrace (Dosage: N/A) was diagnosed with
  • hysterectomy
  • premenstrual syndrome
and. Location: UNITED STATES , 41 years of age, weighting 155.0 lb, Directly after, patient experienced the unwanted or unexpected Estrace side effects: psychological trauma, hysterectomy, pain, abdominal pain upper, cholecystectomy, sexual dysfunction, emotional distress, anxiety, cholecystitis acute.
Associated medications used:
  • Yasmin (Unk)
  • Citalopram
  • Zoloft
  • Yasmin
Patient was hospitalized.

Pain, Influenza Like Illness (7978106-X)
on Dec 12, 2011 Female from UNITED STATES , 67 years of age, was treated with Estrace. Patient felt the following Estrace side effects: pain, influenza like illness. Estrace dosage: N/A.
Multiple prescriptions taken:
  • Zyrtec
  • Sprycel (100 Mg Qd Po)
  • M.v.i.
  • Nortriptyline Hcl
Patient was hospitalized.

Hysterectomy, Pruritus, Photosensitivity Reaction, Swelling Face, Rash Erythematous (7938701-0)
on Nov 14, 2011 Female from UNITED KINGDOM , 74 years of age, was treated with Estrace. After Estrace was administered, patient encountered several Estrace side effects: hysterectomy, pruritus, photosensitivity reaction, swelling face, rash erythematous. Estrace dosage: Dose:2mg.
Multiple concurrent drugs taken:
  • Calcium + Vitamin D
  • Vitamin Tab


Erosive Oesophagitis, Gastrooesophageal Reflux Disease, Diverticulum, Hiatus Hernia, Hypertension, Hypofibrinogenaemia, Gastric Polyps, Regurgitation (7907928-6)
Patient was taking Estrace. Directly after, patient experienced the unwanted or unexpected Estrace side effects: erosive oesophagitis, gastrooesophageal reflux disease, diverticulum, hiatus hernia, hypertension, hypofibrinogenaemia, gastric polyps, regurgitation on Nov 01, 2011 from UNITED STATES Additional patient health information: Female , 77 years of age, weighting 160.1 lb, . Estrace dosage: N/A.
Associated medications used:
  • Nexium
  • Toprol-xl
  • Zantac
  • Zantac (At Bedtime)
  • Potassium Chloride
  • Norvasc
  • Travatan
  • Miacalcin


Wrist Fracture, Tachycardia, Hypertension, Arthralgia, Electrocardiogram St-t Change, Fibula Fracture, Muscle Strain, Femur Fracture, Fall (7894323-1)
Adverse event was reported on Oct 27, 2011 by a Female taking Estrace (Dosage: N/A) was diagnosed with
  • postmenopause
and. Location: UNITED STATES , 66 years of age, weighting 136.7 lb, Patient felt the following Estrace side effects: wrist fracture, tachycardia, hypertension, arthralgia, electrocardiogram st-t change, fibula fracture, muscle strain, femur fracture, fall.
Multiple prescriptions taken:
  • Vitamin E
  • Fosamax
  • Provera
  • Miacalcin
  • Fosamax Plus D
  • Ascorbic Acid
Patient was hospitalized.

Sinusitis, Pain, Rheumatoid Arthritis, Nasopharyngitis, Therapeutic Response Decreased (7882313-4)
on Jun 13, 2011 Female from UNITED STATES , 66 years of age, was treated with Estrace. After Estrace was administered, patient encountered several Estrace side effects: sinusitis, pain, rheumatoid arthritis, nasopharyngitis, therapeutic response decreased. Estrace dosage: N/A.
Multiple concurrent drugs taken:
  • Loratadine
  • Symbicort
  • Enbrel (50 Mg, Qwk)
  • Vitamin D


Vulvovaginal Burning Sensation, Lichen Sclerosus, Vulvovaginal Erythema (7859066-9)
on Oct 05, 2010 Female from UNITED STATES , weighting 121.0 lb, was diagnosed with
  • vulvovaginal erythema
and was treated with Estrace. Directly after, patient experienced the unwanted or unexpected Estrace side effects: vulvovaginal burning sensation, lichen sclerosus, vulvovaginal erythema. Estrace dosage: Unk.
Associated medications used:
  • Prilosec
  • Premarin (Not Provided, But Used Daily)
  • Levothroid
  • Ropinirole
  • Diovan
  • Clobetasol (Unk)
  • Diltiazem


Speech Disorder (7829814-2)
Patient was taking Estrace. Patient felt the following Estrace side effects: speech disorder on Oct 20, 2011 from UNITED STATES Additional patient health information: Female , 72 years of age, weighting 180.0 lb, was diagnosed with
  • vaginal disorder
and. Estrace dosage: 1mg - 2x Weekly.

Pain, Muscle Spasms, Back Pain (7815023-X)
Adverse event was reported on Oct 13, 2011 by a Female taking Estrace (Dosage: 4 Grams Once Vaginally (once Only)) was diagnosed with
  • urethral atrophy
and. Location: UNITED STATES , weighting 160.0 lb, After Estrace was administered, patient encountered several Estrace side effects: pain, muscle spasms, back pain.

Thrombosis, Muscle Spasms (7797554-4)
on Sep 28, 2011 Female from UNITED STATES , weighting 140.3 lb, was treated with Estrace. Directly after, patient experienced the unwanted or unexpected Estrace side effects: thrombosis, muscle spasms. Estrace dosage: N/A.
Associated medications used:
  • Phenytoin (At Bed Time)
  • Synthroid
  • Actos
  • Spironolactone
  • Provera
  • Vimpat
Patient was hospitalized and became disabled.

Dizziness, Memory Impairment, Vertigo, Heart Rate Increased, Confusional State, Nausea (7783376-7)
on Sep 27, 2011 Female from UNITED STATES , 42 years of age, was treated with Estrace. Patient felt the following Estrace side effects: dizziness, memory impairment, vertigo, heart rate increased, confusional state, nausea. Estrace dosage: 1 Gram Vaginally Every 7 Day.

Decreased Interest, Tooth Loss, Metastases To Bone, Neurodermatitis, Ataxia, Pollakiuria, Back Pain, Dyspepsia (7726501-6)
Patient was taking Estrace. After Estrace was administered, patient encountered several Estrace side effects: decreased interest, tooth loss, metastases to bone, neurodermatitis, ataxia, pollakiuria, back pain, dyspepsia on Aug 22, 2011 from UNITED STATES Additional patient health information: Female , weighting 144.0 lb, . Estrace dosage: N/A.
Multiple concurrent drugs taken:
  • Scopolamine
  • Vancomycin
  • Roxanol (20 Mg/ml, Unk)
  • Herceptin
  • Fluconazole (Unk)
  • Levaquin (Intravenous)
  • Calcium Carbonate
  • Vitamin D
Patient was hospitalized.

Headache, Renal Failure, Snoring, Arthralgia, Fatigue, Oedema Peripheral, Narcolepsy, Toothache (7721983-8)
Adverse event was reported on Aug 22, 2011 by a Female taking Estrace (Dosage: N/A) . Location: UNITED STATES , 58 years of age, Directly after, patient experienced the unwanted or unexpected Estrace side effects: headache, renal failure, snoring, arthralgia, fatigue, oedema peripheral, narcolepsy, toothache.
Associated medications used:
  • Aspirin
  • Percocet (One Tablet Qid Prn 10-325)
  • Singulair
  • Plavix
  • Requip
  • Vitamin B-12
  • Omeprazole Cpdr
  • Flexeril (Three Times A Day Prn)


Hot Flush, Depression, Breast Engorgement (7704708-1)
on Nov 11, 2010 Female from UNITED STATES , 40 years of age, weighting 112.4 lb, was treated with Estrace. Patient felt the following Estrace side effects: hot flush, depression, breast engorgement. Estrace dosage: Stopped After 1 Or 2 Months.

Rash (7704703-2)
on Jul 13, 2010 Female from UNITED KINGDOM , 85 years of age, weighting 136.7 lb, was diagnosed with
  • dry skin
and was treated with Estrace. After Estrace was administered, patient encountered several Estrace side effects: rash. Estrace dosage: N/A.
Multiple concurrent drugs taken:
  • Actonel
  • Detrol La (Soft Modified Release Capsules, Increased To 4mg 2 Times A Day)


Breast Cancer (7704702-0)
Patient was taking Estrace. Directly after, patient experienced the unwanted or unexpected Estrace side effects: breast cancer on Oct 06, 2010 from UNITED STATES Additional patient health information: Female , 69 years of age, was diagnosed with
  • menopause
  • hot flush
and. Estrace dosage: Initialy Taken From 1998-1999(1y) And Again Taken From Jun02.

Feeling Hot, Erythema (7665365-6)
Adverse event was reported on Apr 14, 2011 by a Female taking Estrace (Dosage: N/A) . Location: UNITED STATES , weighting 170.2 lb, Patient felt the following Estrace side effects: feeling hot, erythema.
Multiple prescriptions taken:
  • Niaspan (In The Am)
  • Niaspan


Myocardial Infarction, Blood Pressure Increased, Weight Increased, Bundle Branch Block, Dyspnoea, Amnesia (7643701-4)
on Jul 08, 2011 Female from UNITED STATES , 67 years of age, weighting 140.0 lb, was diagnosed with
  • bladder prolapse
and was treated with Estrace. After Estrace was administered, patient encountered several Estrace side effects: myocardial infarction, blood pressure increased, weight increased, bundle branch block, dyspnoea, amnesia. Estrace dosage: 1 G, Qd, Vaginal. Patient was hospitalized.

Chest Discomfort, Sinusitis, Lower Respiratory Tract Infection (7628567-0)
on May 31, 2011 Female from UNITED STATES , 55 years of age, weighting 152.0 lb, was treated with Estrace. Directly after, patient experienced the unwanted or unexpected Estrace side effects: chest discomfort, sinusitis, lower respiratory tract infection. Estrace dosage: N/A.
Associated medications used:
  • Singulair
  • Lisinopril
  • Advair Diskus 100/50
  • Zemaira ((60 Mg/kg 1x/week, Infused 0.08ml Per Kg Per Min (5.7ml Per Min) Intravenous (not Otherwise Specifie)
  • Mucinex
  • Zemaira ((60 Mg/kg 1x/week))
  • Lexapro
  • Spiriva


Showing 1-25 of 469 

Estrace Health Episodes

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Estrace Information

Alternative ESTRACE Names:ESTRADIOL

Active Ingredient: ESTRADIOL

Estrace Dosage, Warnings, Usage.

Side Effects reported to FDA: 469. View Estrace Adverse Reports

Estrace safety alerts: No

Reported deaths: 10

Reported hospitalizations: 50

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