Basal Cell Carcinoma (8479067-X)
on Jun 21, 2012 Female patient from CANADA , weighting 149.9 lb, was treated with Estrace(View Usage). Patient experienced the following unwanted or unexpected effects: basal cell carcinoma. Estrace dosage: N/A.
Patient was taking other medications:

• REMICADE (View Remicade Review and Remicade Label )
• PERMETHRIN (View Permethrin Review and Permethrin Label )
• IMURAN (View Imuran Review and Imuran Label )
• ACETYLSALICYLIC ACID SRT (View Acetylsalicylic Acid Srt Review and Acetylsalicylic Acid Srt Label )
• APPLE CIDER VINEGAR (DIETARY SUPPLEMENT) (View Apple Cider Vinegar (dietary Supplement) Review and Apple Cider Vinegar (dietary Supplement) Label )
• VITAMIN D (View Vitamin D Review and Vitamin D Label )
• VIMOVO (View Vimovo Review and Vimovo Label )
• ACTONEL (View Actonel Review and Actonel Label )

Asthma (8466172-7)
Patient was taking Estrace (View Usage). Patient had the following side effects: asthma (asthma Questions) on Jun 20, 2012 from UNITED STATES Additional patient health information: Female patient , 38 years of age, weighting 123.0 lb, was diagnosed with

• vulvovaginal dryness

and. Estrace dosage: {1 Gram Once Per Day Vag.

Fracture Delayed Union, Muscle Strain, Haemoglobin Decreased, Atypical Femur Fracture, Muscle Spasms, Arthralgia, Haematocrit Decreased, Fall, Post Procedural Complication (8458329-6)
Adverse event was reported on Jun 01, 2012 by a Female patient taking Estrace (View Usage) (Dosage: N/A) . Location: UNITED STATES , 63 years of age, After Estrace was administered, patient had the following side effects: fracture delayed union, muscle strain, haemoglobin decreased, atypical femur fracture, muscle spasms, arthralgia, haematocrit decreased, fall (fall Questions), post procedural complication.
Patient was taking other medications:

• SENNA (SENNOSIDE A+B) (View Senna (sennoside A+b) Review and Senna (sennoside A+b) Label )
• CIPRO (View Cipro Review and Cipro Label )
• SENNA S (DOCUSATE SODIUM, SENNOSIDE A+B) (View Senna S (docusate Sodium, Sennoside A+b) Review and Senna S (docusate Sodium, Sennoside A+b) Label )
• GLUCOSAMINE (GLUCOSAMINE) (View Glucosamine (glucosamine) Review and Glucosamine (glucosamine) Label )
• GARLIC (ALLIUM SATIVUM) (View Garlic (allium Sativum) Review and Garlic (allium Sativum) Label )
• EFFEXOR (View Effexor Review and Effexor Label )
• FISH OIL (FISH OIL) (View Fish Oil (fish Oil) Review and Fish Oil (fish Oil) Label )
• VITAMIN B COMPLEX (CYANOCOBALAMIN) (View Vitamin B Complex (cyanocobalamin) Review and Vitamin B Complex (cyanocobalamin) Label )

Patient was hospitalized.

Urinary Incontinence, Anxiety, Judgement Impaired, Cerebrovascular Accident, Aphasia, Balance Disorder, Renal Pain, Depression, Headache (8440680-7)
on Jun 07, 2012 Female patient from UNITED STATES , 47 years of age, weighting 200.6 lb, was treated with Estrace (View Usage). Patient experienced the following unwanted or unexpected effects: urinary incontinence (urinary incontinence Questions), anxiety (anxiety Questions), judgement impaired, cerebrovascular accident, aphasia (aphasia Questions), balance disorder, renal pain, depression (depression Questions), headache (headache Questions). Estrace dosage: 0.01 %, Unk.
Patient was taking other medications:

• YASMIN (View Yasmin Review and Yasmin Label )
• DARVOCET N 50 (1-2 Tabs Every 4-6 Hours As Needed) (View Darvocet-n 50 Review and Darvocet-n 50 Label )
• PREMARIN (0.625 Mg, Unk) (View Premarin Review and Premarin Label )
• DAYPRO (600 Mg, Daily) (View Daypro Review and Daypro Label )
• TESSALON (100 Mg, Tid) (View Tessalon Review and Tessalon Label )
• VESICARE (5 Mg Daily) (View Vesicare Review and Vesicare Label )

Patient was hospitalized.


Myelodysplastic Syndrome (8432384-1)
on Jun 06, 2012 Female patient from UNITED STATES , 55 years of age, weighting 176.0 lb, was treated with Estrace(View Usage). Patient had the following side effects: myelodysplastic syndrome. Estrace dosage: 0.5 Mg, Qd.
Patient was taking other medications:

• REMERON (30 Mg, Qd) (View Remeron Review and Remeron Label )
• METOPROLOL TARTRATE (100 Unk, Qhs) (View Metoprolol Tartrate Review and Metoprolol Tartrate Label )
• RESTORIL (30 Mg, Qd Hs) (View Restoril Review and Restoril Label )
• METFORMIN HCL (750 Mg, Bid) (View Metformin Hcl Review and Metformin Hcl Label )
• LOVASTATIN (20 Unk, Qhs) (View Lovastatin Review and Lovastatin Label )
• LISINOPRIL (5 Mg, Qd) (View Lisinopril Review and Lisinopril Label )
• PROTONIX (40 Unk, Qd) (View Protonix Review and Protonix Label )
• VICTOZA (1.8 Mg, Qd) (View Victoza Review and Victoza Label )

Patient was hospitalized.

Skin Disorder, Vulvovaginal Pruritus, Bunion, Vulvovaginal Mycotic Infection, Pain Of Skin, Application Site Pain, Skin Lesion (8411326-9)
Patient was taking Estrace (View Usage). After Estrace was administered, patient had the following side effects: skin disorder, vulvovaginal pruritus, bunion, vulvovaginal mycotic infection, pain of skin, application site pain, skin lesion on May 29, 2012 from UNITED STATES Additional patient health information: Female patient , weighting 137.0 lb, . Estrace dosage: Unk.
Patient was taking other medications:

• ESTRING (2 Mg, Unk) (View Estring Review and Estring Label )
• NEXIUM (Unk) (View Nexium Review and Nexium Label )
• IBUPROFEN (ADVIL) (Unk, As Needed) (View Ibuprofen (advil) Review and Ibuprofen (advil) Label )
• AMBIEN (Unk) (View Ambien Review and Ambien Label )

Mood Swings, Retching, Diverticulitis, Gastrooesophageal Reflux Disease, Feeling Abnormal, Irritability, Nausea, Constipation (8380922-X)
Adverse event was reported on May 18, 2012 by a Female patient taking Estrace (View Usage) (Dosage: 1 Mg, 1x/day) was diagnosed with

• menopause (menopause Questions)
• stress (stress Questions)
• abdominal discomfort

and. Location: CANADA , 52 years of age, weighting 152.0 lb, Patient experienced the following unwanted or unexpected effects: mood swings, retching, diverticulitis, gastrooesophageal reflux disease, feeling abnormal, irritability, nausea (nausea Questions), constipation (constipation Questions).
Patient was taking other medications:

• CLONAZEPAM (View Clonazepam Review and Clonazepam Label )
• PANTOPRAZOLE (40 Mg, 1x/day) (View Pantoprazole Review and Pantoprazole Label )
• VARENICLINE TARTRATE (1 Mg, 2x/day) (View Varenicline Tartrate Review and Varenicline Tartrate Label )

Muscle Spasms, Foot Deformity, Alopecia, Tremor, Gait Disturbance, Loss Of Consciousness, Depression, Suicidal Ideation, Fall (8337254-5)
on Apr 17, 2012 Female patient from UNITED STATES , 60 years of age, was treated with Estrace (View Usage). Patient had the following side effects: muscle spasms, foot deformity, alopecia, tremor, gait disturbance, loss of consciousness, depression (depression Questions), suicidal ideation, fall (fall Questions). Estrace dosage: N/A.
Patient was taking other medications:

• THYROID TAB (View Thyroid Tab Review and Thyroid Tab Label )
• HYDROCORTISONE (View Hydrocortisone Review and Hydrocortisone Label )
• PROGESTERONE (View Progesterone Review and Progesterone Label )
• ATIVAN ((0.5 Mg Qid Oral)) (View Ativan Review and Ativan Label )

Pain, Endometrial Cancer (8318872-7)
on Apr 26, 2012 Female patient from UNITED STATES , weighting 270.0 lb, was treated with Estrace(View Usage). After Estrace was administered, patient had the following side effects: pain (pain Questions), endometrial cancer. Estrace dosage: N/A. Patient was hospitalized.

Pulmonary Embolism (8318329-3)
Patient was taking Estrace (View Usage). Patient experienced the following unwanted or unexpected effects: pulmonary embolism (pulmonary embolism Questions) on Apr 26, 2012 from UNITED STATES Additional patient health information: Female patient , 72 years of age, weighting 182.3 lb, was diagnosed with

• pulmonary embolism (pulmonary embolism Questions)

and. Estrace dosage: Estrace 1 Mg Qd P.o..
Patient was taking other medications:

• CELEXA (View Celexa Review and Celexa Label )
• LOVOYL (View Lovoyl Review and Lovoyl Label )

Patient was hospitalized.

Dizziness, Pyrexia, Dry Mouth, Feeling Abnormal (8306811-4)
Adverse event was reported on Apr 19, 2012 by a Female patient taking Estrace (View Usage) (Dosage: Unk, 2x/week) . Location: UNITED STATES , weighting 140.0 lb, Patient had the following side effects: dizziness (dizziness Questions), pyrexia, dry mouth, feeling abnormal.
Patient was taking other medications:

• AMITRIPTYLINE (12.5 Mg, 1x/day) (View Amitriptyline Review and Amitriptyline Label )

Uterine Disorder, Product Substitution Issue (8290507-1)
on Apr 12, 2012 Female patient from UNITED STATES , weighting 114.0 lb, was diagnosed with

• infertility (infertility Questions)

and was treated with Estrace (View Usage). After Estrace was administered, patient had the following side effects: uterine disorder, product substitution issue. Estrace dosage: 2 Mg Po Tid.

Injection Site Reaction, Breast Discomfort, Ocular Hyperaemia, Face Oedema, Skin Sensitisation, Rash, Eye Swelling, Dry Skin, Alopecia (8290264-9)
on Apr 05, 2012 Female patient from UNITED STATES , 54 years of age, weighting 118.0 lb, was treated with Estrace(View Usage). Patient experienced the following unwanted or unexpected effects: injection site reaction, breast discomfort, ocular hyperaemia, face oedema, skin sensitisation, rash (rash Questions), eye swelling, dry skin, alopecia. Estrace dosage: 1 Mg, Qd.
Patient was taking other medications:

• CALCIUM CARBONATE (Unk) (View Calcium Carbonate Review and Calcium Carbonate Label )
• PROLIA (60 Mg, Q6mo) (View Prolia Review and Prolia Label )
• LISNOP AM (Unk) (View Lisnop-am Review and Lisnop-am Label )
• KLONOPIN (1 Mg, Bid) (View Klonopin Review and Klonopin Label )
• VITAMIN D (Unk) (View Vitamin D Review and Vitamin D Label )

Aphagia, Malaise, Fungal Infection, Weight Decreased, Mobility Decreased, Treatment Noncompliance (8269203-2)
Patient was taking Estrace (View Usage). Patient had the following side effects: aphagia, malaise, fungal infection (fungal infection Questions), weight decreased, mobility decreased, treatment noncompliance on Mar 30, 2012 from UNITED STATES Additional patient health information: Female patient , 43 years of age, . Estrace dosage: N/A.
Patient was taking other medications:

• CLINDAMYCIN (View Clindamycin Review and Clindamycin Label )
• DIFLUCAN (1df) (View Diflucan Review and Diflucan Label )
• PREVACID 24 HR (15mg Per Day) (View Prevacid 24 Hr Review and Prevacid 24 Hr Label )

Periorbital Oedema, Diarrhoea, Fatigue, Eye Oedema, Oedema Peripheral, Muscle Fatigue (8269034-3)
Adverse event was reported on Aug 17, 2009 by a Female patient taking Estrace (View Usage) (Dosage: N/A) . Location: UNITED STATES , 61 years of age, weighting 160.1 lb, After Estrace was administered, patient had the following side effects: periorbital oedema, diarrhoea, fatigue, eye oedema, oedema peripheral, muscle fatigue.
Patient was taking other medications:

• ASPIRIN (View Aspirin Review and Aspirin Label )
• GLUCOSAMINE (GLUCOSAMINE) (View Glucosamine (glucosamine) Review and Glucosamine (glucosamine) Label )
• PREVERA (MEDROXYPROGESTERONE ACETATE) (View Prevera (medroxyprogesterone Acetate) Review and Prevera (medroxyprogesterone Acetate) Label )
• MULTI VITAMINS (View Multi-vitamins Review and Multi-vitamins Label )
• VOLTAREN (View Voltaren Review and Voltaren Label )
• IRON (IRON) (View Iron (iron) Review and Iron (iron) Label )
• GLEEVEC (400 Mg, Qd, Oral) (View Gleevec Review and Gleevec Label )

Spinal Osteoarthritis (8246293-4)
on Mar 29, 2012 Female patient from UNITED STATES , 54 years of age, weighting 116.0 lb, was diagnosed with

• breast cancer metastatic

and was treated with Estrace (View Usage). Patient experienced the following unwanted or unexpected effects: spinal osteoarthritis. Estrace dosage: Estradiol (estrace) 10mg 3 Times Daily Per Mouth.

Insomnia, Endometriosis, Anxiety, Dry Eye, Blood Thyroid Stimulating Hormone Increased, Tremor, Cholelithiasis, Depression (8241706-6)
on Mar 20, 2012 Female patient from UNITED STATES , weighting 174.2 lb, was treated with Estrace(View Usage). Patient had the following side effects: insomnia, endometriosis (endometriosis Questions), anxiety (anxiety Questions), dry eye, blood thyroid stimulating hormone increased, tremor, cholelithiasis, depression (depression Questions). Estrace dosage: Daily Dose 75 Mg.
Patient was taking other medications:

• SYNTHROID (View Synthroid Review and Synthroid Label )

Patient was hospitalized.

Genital Burning Sensation, Quality Of Life Decreased, Educational Problem, Impaired Work Ability (8234103-0)
Patient was taking Estrace (View Usage). After Estrace was administered, patient had the following side effects: genital burning sensation, quality of life decreased, educational problem, impaired work ability on Mar 26, 2012 from UNITED STATES Additional patient health information: Female patient , 18 years of age, weighting 140.0 lb, was diagnosed with

• vulvovaginal pain

and. Estrace dosage: A Pea Size Drop Topically.

Face Oedema, Swelling, Alopecia, Arthralgia, Skin Hypertrophy, Ocular Hyperaemia, Dry Skin, Neck Pain, Somnolence (8223033-6)
Adverse event was reported on Mar 15, 2012 by a Female patient taking Estrace (View Usage) (Dosage: 1 Mg, Qd) . Location: UNITED STATES , 54 years of age, weighting 120.0 lb, Patient experienced the following unwanted or unexpected effects: face oedema, swelling, alopecia, arthralgia, skin hypertrophy, ocular hyperaemia, dry skin, neck pain, somnolence.
Patient was taking other medications:

• CALCIUM CARBONATE (View Calcium Carbonate Review and Calcium Carbonate Label )
• PROLIA (60 Mg, Q6mo) (View Prolia Review and Prolia Label )
• VITAMIN D (View Vitamin D Review and Vitamin D Label )

Abdominal Distension, Cardiac Failure Congestive, Bronchitis, Headache, Blood Pressure Increased, Fluid Retention, Cystocele, Urine Sodium Decreased, Palpitations (8172999-1)
on Feb 17, 2012 Female patient from UNITED STATES , 81 years of age, weighting 84.88 lb, was diagnosed with

• atrophy
• preoperative care

and was treated with Estrace (View Usage). Patient had the following side effects: abdominal distension, cardiac failure congestive, bronchitis (bronchitis Questions), headache (headache Questions), blood pressure increased, fluid retention, cystocele, urine sodium decreased, palpitations. Estrace dosage: 1 G 2 Times Per Week, Vaginal. Patient was hospitalized.

Depression, Anxiety (8171309-3)
on Nov 18, 2011 Female patient from UNITED STATES , 61 years of age, was treated with Estrace(estradiol)(estradiol)(View Usage). After Estrace was administered, patient had the following side effects: depression (depression Questions), anxiety (anxiety Questions). Estrace(estradiol)(estradiol) dosage: N/A.

Cholecystectomy, Cholecystitis, Night Sweats, Abdominal Distension, Oedema Peripheral, Cholelithiasis (8139172-4)
Patient was taking Estrace (View Usage). Patient experienced the following unwanted or unexpected effects: cholecystectomy, cholecystitis, night sweats, abdominal distension, oedema peripheral, cholelithiasis on Feb 09, 2012 from UNITED STATES Additional patient health information: Female patient , 61 years of age, weighting 182.0 lb, . Estrace dosage: N/A.
Patient was taking other medications:

• PRISTIQ (View Pristiq Review and Pristiq Label )
• NITROSTAT (Unk, Prn) (View Nitrostat Review and Nitrostat Label )
• CRANBERRY /01512301/ (View Cranberry /01512301/ Review and Cranberry /01512301/ Label )
• MULTIVITAMIN /00097801/ (View Multivitamin /00097801/ Review and Multivitamin /00097801/ Label )
• VICTOZA (1.8 Mg, Qd) (View Victoza Review and Victoza Label )
• METFORMIN HCL (Unk, Bid) (View Metformin Hcl Review and Metformin Hcl Label )
• LASIX (Unk, Prn) (View Lasix Review and Lasix Label )
• ALLEGRA D 12 HOUR (Unk, Prn) (View Allegra-d 12 Hour Review and Allegra-d 12 Hour Label )

Transient Ischaemic Attack (8138059-0)
Adverse event was reported on Feb 06, 2012 by a Female patient taking Estrace (View Usage) (Dosage: 1 Gram Per Day, Vaginal : Twice Weekly, Vaginal) was diagnosed with

• vulvovaginal dryness
• pelvic floor muscle weakness

and. Location: UNITED STATES , 72 years of age, Patient had the following side effects: transient ischaemic attack. Patient was hospitalized.

Urinary Tract Infection (8133784-X)
on Feb 13, 2012 Female patient from UNITED STATES , 63 years of age, weighting 160.0 lb, was diagnosed with

• vaginal disorder

and was treated with Estrace (View Usage). After Estrace was administered, patient had the following side effects: urinary tract infection (urinary tract infection Questions). Estrace dosage: Apply 1/4 Applictorfull.
Patient was taking other medications:

• ZETIA (View Zetia Review and Zetia Label )
• PRAVASTATIN (View Pravastatin Review and Pravastatin Label )

Urinary Tract Infection (8133783-8)
on Feb 13, 2012 Female patient from UNITED STATES , 85 years of age, weighting 150.0 lb, was diagnosed with

• prophylaxis urinary tract infection

and was treated with Estrace(View Usage). Patient experienced the following unwanted or unexpected effects: urinary tract infection (urinary tract infection Questions). Estrace dosage: Apply 1 Figer Tipfull.
Patient was taking other medications:

• COUMADIN (View Coumadin Review and Coumadin Label )
• RAMIPRIL (View Ramipril Review and Ramipril Label )
• ZOCOR (View Zocor Review and Zocor Label )
• ZETIA (View Zetia Review and Zetia Label )