Common Evista Side Effects


The most commonly reported Evista side effects (click to view or check a box to report):

Fall (133)
Breast Cancer (122)
Pulmonary Embolism (115)
Deep Vein Thrombosis (109)
Dizziness (85)
Muscle Spasms (81)
Oedema Peripheral (79)
Pain In Extremity (79)
Bone Density Decreased (75)
Cerebrovascular Accident (72)
Arthralgia (71)
Hot Flush (70)
Pain (67)
Thrombosis (60)
Hip Fracture (60)
Back Pain (59)
Cerebral Infarction (58)
Breast Cancer Female (55)
Transient Ischaemic Attack (54)
Visual Acuity Reduced (52)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Evista Side Effects Reported to FDA



Evista Side Effect Report#9960200
Local Swelling, Pain In Extremity, Deep Vein Thrombosis, Deep Vein Thrombosis
This is a report of a 80-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: osteoporosis, who was treated with Evista 60 Mg (dosage: 1 Pill Qd Oral, start time: NS), combined with:
  • Coumadin
and developed a serious reaction and side effect(s): Local Swelling, Pain In Extremity, Deep Vein Thrombosis, Deep Vein Thrombosis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Evista 60 Mg treatment in female patients, resulting in Local Swelling side effect. The patient was hospitalized.
Evista Side Effect Report#9921178
Nausea, Abdominal Pain
This report suggests a potential Evista Nausea side effect(s) that can have serious consequences. A 78-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: osteoporosis and used Evista (dosage: NA) starting NS. After starting Evista the patient began experiencing various side effects, including: Nausea, Abdominal PainAdditional drugs used concurrently: NA. Although Evista demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Nausea, may still occur.
Evista Side Effect Report#9915733
Local Swelling, Arthralgia, Headache, Pain, Depression, Epistaxis
This Local Swelling problem was reported by a consumer or non-health professional from US. A 67-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: bone density decreased. On
Nov 19, 2013 this consumer started treatment with Evista (dosage: 1 Pill Once Daily). The following drugs were being taken at the same time:
  • Simply Slim
When using Evista, the patient experienced the following unwanted symptoms/side effects: Local Swelling, Arthralgia, Headache, Pain, Depression, EpistaxisAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Local Swelling, may become evident only after a product is in use by the general population.
Evista Side Effect Report#9911657
Femur Fracture, Fall
This Femur Fracture side effect was reported by a consumer or non-health professional from JP. A 85-year-old female patient (weight:NA) experienced the following symptoms/conditions: osteoporosis.The patient was prescribed Evista (drug dosage: Unk), which was initiated on NS. Concurrently used drugs: NA..After starting to take Evista the consumer reported adverse symptoms, such as: Femur Fracture, FallThese side effects may potentially be related to Evista.
Evista Side Effect Report#9893862
Angina Pectoris, Pain
This is a report of a 82-year-old female patient (weight: NA) from JP, suffering from the following health symptoms/conditions: osteoporosis,insomnia,gastritis,stomatitis, who was treated with Evista (dosage: Unk, start time:
Nov 26, 2011), combined with:
  • Myslee (Unk)
  • Taiproton (Unk)
  • Dexaltin (Unk)
  • Celecox
  • Lyrica
  • Opalmon
and developed a serious reaction and side effect(s): Angina Pectoris, Pain after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Evista treatment in female patients, resulting in Angina Pectoris side effect.
Evista Side Effect Report#9834410
Groin Abscess, Venous Thrombosis Limb
This report suggests a potential Evista Groin Abscess side effect(s) that can have serious consequences. A female patient (weight: NA) from JP was diagnosed with the following symptoms/conditions: osteoporosis,hyperlipidaemia,hypertension and used Evista (dosage: 60 Mg, Qd) starting NS. After starting Evista the patient began experiencing various side effects, including: Groin Abscess, Venous Thrombosis LimbAdditional drugs used concurrently:
  • Bezatol (200 Mg, Bid)
  • Norvasc (5 Mg, Qd)
The patient was hospitalized. Although Evista demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Groin Abscess, may still occur.
Evista Side Effect Report#9826293
Muscular Weakness, Pain In Extremity, Activities Of Daily Living Impaired
This Muscular Weakness problem was reported by a consumer or non-health professional from US. A 51-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: breast hyperplasia. On
Apr 15, 2013 this consumer started treatment with Evista (dosage: NA). The following drugs were being taken at the same time:
  • Bupropion Hcl
  • Montelukast
When using Evista, the patient experienced the following unwanted symptoms/side effects: Muscular Weakness, Pain In Extremity, Activities Of Daily Living ImpairedAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Muscular Weakness, may become evident only after a product is in use by the general population.
Evista Side Effect Report#9684671
Fluid Retention, Blood Pressure Increased, Tenderness, Fatigue, Acute Stress Disorder
This Fluid Retention side effect was reported by a health professional from US. A 66-year-old female patient (weight:NA) experienced the following symptoms/conditions: osteopenia.The patient was prescribed Evista (drug dosage: 60mg, Once Daily), which was initiated on 2007. Concurrently used drugs: NA..After starting to take Evista the consumer reported adverse symptoms, such as: Fluid Retention, Blood Pressure Increased, Tenderness, Fatigue, Acute Stress DisorderThese side effects may potentially be related to Evista.
Evista Side Effect Report#9681398
Liver Injury
This is a report of a 80-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: osteoporosis, who was treated with Evista (dosage: NA, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Liver Injury after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Evista treatment in female patients, resulting in Liver Injury side effect.
Evista Side Effect Report#9678765
Hepatic Function Abnormal
This report suggests a potential Evista Hepatic Function Abnormal side effect(s) that can have serious consequences. A 65-year-old female patient (weight: NA) from JP was diagnosed with the following symptoms/conditions: NA and used Evista (dosage: Unk) starting NS. After starting Evista the patient began experiencing various side effects, including: Hepatic Function AbnormalAdditional drugs used concurrently:
  • Amaryl (1 Mg, Unk)
  • Kinedak (Unk)
  • Methycobal (Unk)
  • Glactiv (1 Df, Qd)
  • Atorvastatin (Unk, Qd)
  • Calfina (0.5 Ug, Qd)
  • Metformin Hydrochloride (Unk)
Although Evista demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Hepatic Function Abnormal, may still occur.
Evista Side Effect Report#9652886
Feeling Hot, Nausea
This Feeling Hot problem was reported by a consumer or non-health professional from US. A 77-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: bone disorder,breast cancer. On NS this consumer started treatment with Evista (dosage: 1 Once Daily). The following drugs were being taken at the same time: NA. When using Evista, the patient experienced the following unwanted symptoms/side effects: Feeling Hot, NauseaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Feeling Hot, may become evident only after a product is in use by the general population.
Evista Side Effect Report#9643249
Renal Haemorrhage, Platelet Count Decreased, Protein Urine Present, Blood Urine Present
This Renal Haemorrhage side effect was reported by a consumer or non-health professional from JP. A 80-year-old female patient (weight:NA) experienced the following symptoms/conditions: osteoporosis postmenopausal.The patient was prescribed Evista (drug dosage: 60 Mg, Qd), which was initiated on NS. Concurrently used drugs:
  • Gaster (40 Mg, Qd)
  • Micardis (40 Mg, Qd)
  • Calcium (200 Mg, Tid)
  • Alfarol (0.25 Ug, Tid)
  • Methycobal (500 Ug, Tid)
  • Artist (10 Mg, Qd)
  • Norvasc
.After starting to take Evista the consumer reported adverse symptoms, such as: Renal Haemorrhage, Platelet Count Decreased, Protein Urine Present, Blood Urine PresentThese side effects may potentially be related to Evista. The patient was hospitalized.
Evista Side Effect Report#9609006
This is a report of a 81-year-old female patient (weight: NA) from JP, suffering from the following health symptoms/conditions: osteoporosis postmenopausal,hypertension, who was treated with Evista (dosage: Unk, start time: 201103), combined with:
  • Micardis
  • Mevalotin
and developed a serious reaction and side effect(s): after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Evista treatment in female patients, resulting in Death side effect.
Evista Side Effect Report#9586371
Myocardial Infarction, Lip And/or Oral Cavity Cancer, Thrombosis
This report suggests a potential Evista Myocardial Infarction side effect(s) that can have serious consequences. A 77-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: osteoporosis and used Evista (dosage: Unk) starting NS. After starting Evista the patient began experiencing various side effects, including: Myocardial Infarction, Lip And/or Oral Cavity Cancer, ThrombosisAdditional drugs used concurrently:
  • Vytorin
  • Novolog
Although Evista demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Myocardial Infarction, may still occur.
Evista Side Effect Report#9566010
Hypertension, Visual Acuity Reduced
This Hypertension problem was reported by a consumer or non-health professional from US. A 71-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: osteoporosis. On
Sep 06, 2013 this consumer started treatment with Evista (dosage: NA). The following drugs were being taken at the same time: NA. When using Evista, the patient experienced the following unwanted symptoms/side effects: Hypertension, Visual Acuity ReducedAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Hypertension, may become evident only after a product is in use by the general population.
Evista Side Effect Report#9558815
Fall, Femur Fracture, Scapula Fracture, Sepsis, Pneumonia, Thrombocytopenia, Foot Fracture, Rib Fracture, Bone Density Decreased
This Fall side effect was reported by a consumer or non-health professional from US. A 84-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Evista (drug dosage: NA), which was initiated on
Apr 13, 2007. Concurrently used drugs:
  • Fosamax
  • Boniva (150 Mg, Monthly (1/m))
  • Aciphex
  • Pepcid /00706001/
  • Miacalcin
  • Calcium
  • Vitamin D Nos
  • Lovenox
.After starting to take Evista the consumer reported adverse symptoms, such as: Fall, Femur Fracture, Scapula Fracture, Sepsis, Pneumonia, Thrombocytopenia, Foot Fracture, Rib Fracture, Bone Density DecreasedThese side effects may potentially be related to Evista. The patient was hospitalized.
Evista Side Effect Report#9549634
Invasive Ductal Breast Carcinoma
This is a report of a female patient (weight: NA) from US, suffering from the following health symptoms/conditions: osteopenia, who was treated with Evista (dosage: 60 Mg, Qd, start time: NS), combined with:
  • Singulair
  • Lipitor
  • Advair
  • Albuterol /00139501/
  • Xopenex Hfa
  • Flonase
  • Citracal Plus
  • Iron
and developed a serious reaction and side effect(s): Invasive Ductal Breast Carcinoma after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Evista treatment in female patients, resulting in Invasive Ductal Breast Carcinoma side effect.
Evista Side Effect Report#9532204
Breast Cancer
This report suggests a potential Evista Breast Cancer side effect(s) that can have serious consequences. A 65-year-old female patient (weight: NA) from JP was diagnosed with the following symptoms/conditions: osteoporosis and used Evista (dosage: Unk) starting NS. After starting Evista the patient began experiencing various side effects, including: Breast CancerAdditional drugs used concurrently: NA. Although Evista demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Breast Cancer, may still occur.
Evista Side Effect Report#9531474
Hot Flush
This Hot Flush problem was reported by a consumer or non-health professional from US. A 56-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: menopausal symptoms. On
May 20, 2013 this consumer started treatment with Evista (dosage: 1 Tablet Once Daily Taken By Mouth). The following drugs were being taken at the same time: NA. When using Evista, the patient experienced the following unwanted symptoms/side effects: Hot FlushAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Hot Flush, may become evident only after a product is in use by the general population.
Evista Side Effect Report#9523242
Creatinine Renal Clearance Decreased
This Creatinine Renal Clearance Decreased side effect was reported by a physician from JP. A 90-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Evista (drug dosage: 60 Mg, Qod), which was initiated on NS. Concurrently used drugs: NA..After starting to take Evista the consumer reported adverse symptoms, such as: Creatinine Renal Clearance DecreasedThese side effects may potentially be related to Evista.
Evista Side Effect Report#9511783
Spinal Compression Fracture
This is a report of a 67-year-old female patient (weight: NA) from JP, suffering from the following health symptoms/conditions: osteoporosis postmenopausal, who was treated with Evista (dosage: 60 Mg, Qd, start time: 201304), combined with: NA. and developed a serious reaction and side effect(s): Spinal Compression Fracture after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Evista treatment in female patients, resulting in Spinal Compression Fracture side effect. The patient was hospitalized.
Evista Side Effect Report#9502503
Cataract
This report suggests a potential Evista Cataract side effect(s) that can have serious consequences. A 86-year-old female patient (weight: NA) from JP was diagnosed with the following symptoms/conditions: NA and used Evista (dosage: Unk) starting NS. After starting Evista the patient began experiencing various side effects, including: CataractAdditional drugs used concurrently: NA. Although Evista demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Cataract, may still occur.
Evista Side Effect Report#9483880
Endometrial Hyperplasia
This Endometrial Hyperplasia problem was reported by a consumer or non-health professional from JP. A 54-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On 2006 this consumer started treatment with Evista (dosage: 60 Mg, Qd). The following drugs were being taken at the same time: NA. When using Evista, the patient experienced the following unwanted symptoms/side effects: Endometrial HyperplasiaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Endometrial Hyperplasia, may become evident only after a product is in use by the general population.
Evista Side Effect Report#9474898
Femur Fracture, Tibia Fracture, Rib Fracture
This Femur Fracture side effect was reported by a consumer or non-health professional from US. A female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Evista (drug dosage: NA), which was initiated on 201110. Concurrently used drugs:
  • Tamoxifen
  • Aspirin (81 Mg, Prn)
  • Tramadol
.After starting to take Evista the consumer reported adverse symptoms, such as: Femur Fracture, Tibia Fracture, Rib FractureThese side effects may potentially be related to Evista.
Evista Side Effect Report#9466053
Impaired Healing, No Therapeutic Response, Osteonecrosis Of Jaw
This is a report of a 63-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: bone density abnormal,breast cancer,prophylaxis, who was treated with Evista (dosage: 1 Pill Once Daily Taken By Mouth, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Impaired Healing, No Therapeutic Response, Osteonecrosis Of Jaw after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Evista treatment in female patients, resulting in Impaired Healing side effect.


1 of 94 


The appearance of Evista on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

What are common Evista Side Effects for Women?

Women Side Effects Reports
Fall 133
Breast Cancer 122
Pulmonary Embolism 115
Deep Vein Thrombosis 107
Dizziness 85
Muscle Spasms 80
Pain In Extremity 79
Oedema Peripheral 78
Bone Density Decreased 75
Cerebrovascular Accident 71

What are common Evista Side Effects for Men?

Men Side Effects Reports
Deep Vein Thrombosis 2
Arthralgia 1
Cardiac Failure 1
Coronary Artery Disease 1
Disseminated Intravascular Coagulation 1
Hypertension 1
Muscle Spasms 1
No Adverse Event 1
Oedema Peripheral 1
Shock Haemorrhagic 1

Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Evista reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

    Discuss Evista Side Effects

    Did You Have a Evista Side Effect?

    Yes, Severe
    Yes, Moderate
    Yes, Minor
    No

    How Effective is Evista for You?

    Exceeded Expectations
    Effective
    Somewhat Effective
    Not Effective

    Evista Safety Alerts, Active Ingredients, Usage Information

    NDC 0002-4165
    Type HUMAN PRESCRIPTION DRUG
    Proprietary Name Evista
    Name Raloxifene hydrochloride
    Dosage Form TABLET
    Route ORAL
    On market since 19980106
    Labeler Eli Lilly and Company
    Active Ingredient(s) RALOXIFENE HYDROCHLORIDE
    Strength(s) 60
    Unit(s) mg/1
    Pharma Class Estrogen Agonist/Antagonist [EPC],Selective Estrogen Receptor Modulators [MoA]

    Evista Dosage, Warnings, Usage.

    Side Effects reported to FDA: 2350

    Evista safety alerts: No

    Reported deaths: 121

    Reported hospitalizations: 1022

    Latest Evista clinical trials

    privacy policy