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Fastic Side Effects

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Common Fastic Side Effects


The most commonly reported Fastic side effects (click to view or check a box to report):

Interstitial Lung Disease (7)
Convulsion (6)
Blood Antidiuretic Hormone Increased (5)
Blood Osmolarity Decreased (5)
Aspartate Aminotransferase Increased (5)
Depressed Level Of Consciousness (5)
Hallucination (5)
Hyponatraemia (5)
Inappropriate Antidiuretic Hormone Secretion (5)
Blood Bilirubin Increased (4)
Alanine Aminotransferase Increased (4)
Hepatic Function Abnormal (4)
Dysarthria (4)
Blood Lactate Dehydrogenase Increased (3)
Amnesia (3)
Gamma-glutamyltransferase Increased (3)
Glycosylated Haemoglobin Increased (3)
Liver Disorder (3)
Lymphoma (3)
Epilepsy (2)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Fastic Side Effects Reported to FDA



Fastic Side Effect Report#7967163-2
Bladder Cancer
This is a report of a 61-year-old male patient (weight: NA) from Japan, suffering from the following health symptoms/conditions: NA, who was treated with Fastic (natelginide) (dosage: NA, start time:
Nov 12, 2009), combined with:
  • Actos (15 Mg (15 Mg,1 In 1 D) Per Oral ; 30 Mg (30 Mg, 1 In 1 D) Per Oral)
  • Actos (15 Mg (15 Mg,1 In 1 D) Per Oral ; 30 Mg (30 Mg, 1 In 1 D) Per Oral)
  • Diovan
  • Lantus
  • Aspirin
  • Crestor
  • Norvasc
  • Novolog
and developed a serious reaction and side effect(s): Bladder Cancer after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Fastic (natelginide) treatment in male patients, resulting in Bladder Cancer side effect. The patient was hospitalized.
Fastic Side Effect Report#7593626-8
Bladder Cancer, Prostate Cancer
This report suggests a potential Fastic (nateglinide) Bladder Cancer side effect(s) that can have serious consequences. A 68-year-old male patient (weight: NA) from Japan was diagnosed with the following symptoms/conditions: NA and used Fastic (nateglinide) (dosage: NA) starting
Mar 01, 2010. After starting Fastic (nateglinide) the patient began experiencing various side effects, including: Bladder Cancer, Prostate CancerAdditional drugs used concurrently:
  • Basen (voglibose)
  • Takeperon (lansoprazole)
  • Actos (15 Mg (15 Mg, 1 D) Per Oral,)
The patient was hospitalized. Although Fastic (nateglinide) demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Bladder Cancer, may still occur.
Fastic Side Effect Report#7409963-3
Liver Disorder, Glycosylated Haemoglobin Increased, Blood Glucose Increased
This Liver Disorder problem was reported by a consumer or non-health professional from Japan. A 38-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Feb 17, 2009 this consumer started treatment with Fastic (dosage: 180 Mg, Qd). The following drugs were being taken at the same time:
  • Metformin Hcl (500 Mg, Qd)
  • Actos (30 Mg, Qd)
When using Fastic, the patient experienced the following unwanted symptoms/side effects: Liver Disorder, Glycosylated Haemoglobin Increased, Blood Glucose IncreasedAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Liver Disorder, may become evident only after a product is in use by the general population.
Fastic Side Effect Report#7331612-3
Hypokalaemia, Oedema Peripheral, Decreased Appetite, Rash, Gastric Ulcer, Stomatitis, Constipation, Aspartate Aminotransferase Increased, Pruritus
This Hypokalaemia side effect was reported by a physician from Japan. A 70-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Fastic (drug dosage: Daily Dose 270 Mg), which was initiated on
Aug 02, 2008. Concurrently used drugs:
  • Tagamet (Daily Dose 800 Mg)
  • Sorafenib (raf Kinase Inhibitor) (Daily Dose 400 Mg)
  • Sorafenib (raf Kinase Inhibitor) (Daily Dose 400 Mg)
  • Cortril (Daily Dose 10.5 Mg)
  • Sorafenib (raf Kinase Inhibitor) (Daily Dose 400 Mg)
  • Sorafenib (raf Kinase Inhibitor) (Daily Dose 800 Mg)
.After starting to take Fastic the consumer reported adverse symptoms, such as: Hypokalaemia, Oedema Peripheral, Decreased Appetite, Rash, Gastric Ulcer, Stomatitis, Constipation, Aspartate Aminotransferase Increased, PruritusThese side effects may potentially be related to Fastic. The patient was hospitalized.
Fastic Side Effect Report#7241716-1
Interstitial Lung Disease, Renal Impairment, Respiratory Failure, Urine Output Decreased, Pulmonary Oedema, Cardiac Arrest
This is a report of a male patient (weight: NA) from Japan, suffering from the following health symptoms/conditions: diabetes mellitus, who was treated with Fastic (dosage: 90 Mg, Unk, start time:
Jul 24, 2007), combined with:
  • Ceftriaxone Sodium (Unk)
  • Diovan (40 Mg, Qd)
  • Takepron (15 Mg, Unk)
  • Diart (30 Mg, Unk)
  • Minocycline Hydrochloride (100 Mg)
  • Allopurinol (100 Mg, Unk)
  • Ulcerlmin (3 G, Unk)
and developed a serious reaction and side effect(s): Interstitial Lung Disease, Renal Impairment, Respiratory Failure, Urine Output Decreased, Pulmonary Oedema, Cardiac Arrest after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Fastic treatment in male patients, resulting in Interstitial Lung Disease side effect. The patient was hospitalized.
Fastic Side Effect Report#6717923-0
Hypoglycaemia, Infection
This report suggests a potential Fastic Hypoglycaemia side effect(s) that can have serious consequences. A 66-year-old male patient (weight: NA) from Japan was diagnosed with the following symptoms/conditions: diabetes mellitus,infection and used Fastic (dosage: 90 Mg Daily) starting
Mar 15, 2010. After starting Fastic the patient began experiencing various side effects, including: Hypoglycaemia, InfectionAdditional drugs used concurrently:
  • Cravit (Unk)
  • Allopurinol
  • Hornel
  • Mucosta
  • Norvasc
  • Basen
  • Epadel
The patient was hospitalized. Although Fastic demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Hypoglycaemia, may still occur.
Fastic Side Effect Report#6361582-6
Atrioventricular Block Complete
This Atrioventricular Block Complete problem was reported by a consumer or non-health professional from Japan. A 80-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: diabetes mellitus. On
Mar 03, 2009 this consumer started treatment with Fastic (dosage: 90 Mg/day). The following drugs were being taken at the same time:
  • Famotidine D
  • Voglibose
  • Allorine (100 Mg, Unk)
When using Fastic, the patient experienced the following unwanted symptoms/side effects: Atrioventricular Block CompleteThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Atrioventricular Block Complete, may become evident only after a product is in use by the general population.
Fastic Side Effect Report#6255124-3
Liver Disorder
This Liver Disorder side effect was reported by a consumer or non-health professional from Japan. A 39-year-old male patient (weight:NA) experienced the following symptoms/conditions: type 2 diabetes mellitus.The patient was prescribed Fastic (drug dosage: 270 Mg/day), which was initiated on
Feb 20, 2009. Concurrently used drugs:
  • Melbin (500 Mg, Unk)
.After starting to take Fastic the consumer reported adverse symptoms, such as: Liver DisorderThese side effects may potentially be related to Fastic.
Fastic Side Effect Report#5659488-0
Blood Creatinine Increased, Blood Glucose Increased, Blood Lactate Dehydrogenase Increased, Blood Potassium Increased, Blood Urea Increased, C-reactive Protein Increased, Gamma-glutamyltransferase Increased, Lymphocyte Percentage Increased, Platelet Count Increased
This is a report of a 60-year-old male patient (weight: NA) from Japan, suffering from the following health symptoms/conditions: diabetes mellitus, who was treated with Fastic (dosage: 90 Mg/day, start time:
Dec 05, 2007), combined with:
  • Starsis (270 Mg/day)
  • Basen (0.6 Mg/day)
  • Melbin (500 Mg, Unk)
  • Glycoran (750 Mg, Unk)
  • Risumic (Unk, Unk)
  • Risumic
and developed a serious reaction and side effect(s): Blood Creatinine Increased, Blood Glucose Increased, Blood Lactate Dehydrogenase Increased, Blood Potassium Increased, Blood Urea Increased, C-reactive Protein Increased, Gamma-glutamyltransferase Increased, Lymphocyte Percentage Increased, Platelet Count Increased after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Fastic treatment in male patients, resulting in Blood Creatinine Increased side effect. The patient was hospitalized.
Fastic Side Effect Report#5317637-8
Depression, Hypoglycaemia
This report suggests a potential Fastic Depression side effect(s) that can have serious consequences. A 87-year-old female patient (weight: NA) from Japan was diagnosed with the following symptoms/conditions: diabetes mellitus and used Fastic (dosage: NA) starting NS. After starting Fastic the patient began experiencing various side effects, including: Depression, HypoglycaemiaAdditional drugs used concurrently:
  • Minocycline Hcl
Although Fastic demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Depression, may still occur.
Fastic Side Effect Report#5237847-8
Interstitial Lung Disease
This Interstitial Lung Disease problem was reported by a physician from Japan. A 71-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: diabetes mellitus. On
Jul 21, 2006 this consumer started treatment with Fastic (dosage: 180 Mg/day). The following drugs were being taken at the same time:
  • Olmetec (20 Mg/day)
  • Mobic (10 Mg/day)
  • Lipidil (40 Mg/day)
  • Artist (10 Mg, Unk)
  • Calblock (16 Mg, Unk)
When using Fastic, the patient experienced the following unwanted symptoms/side effects: Interstitial Lung DiseaseThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Interstitial Lung Disease, may become evident only after a product is in use by the general population.
Fastic Side Effect Report#5192730-1
Interstitial Lung Disease
This Interstitial Lung Disease side effect was reported by a physician from Japan. A 71-year-old male patient (weight:NA) experienced the following symptoms/conditions: diabetes mellitus.The patient was prescribed Fastic (drug dosage: 180 Mg/day), which was initiated on
Jul 21, 2006. Concurrently used drugs:
  • Olmetec (20 Mg/day)
  • Mobic (10 Mg/day)
  • Lipidil (40 Mg/day)
  • Artist (10 Mg, Unk)
  • Calblock (16 Mg, Unk)
.After starting to take Fastic the consumer reported adverse symptoms, such as: Interstitial Lung DiseaseThese side effects may potentially be related to Fastic. The patient was hospitalized.
Fastic Side Effect Report#5141277-7
International Normalised Ratio Increased, Prothrombin Time Prolonged
This is a report of a 75-year-old female patient (weight: NA) from Japan, suffering from the following health symptoms/conditions: diabetes mellitus, who was treated with Fastic (dosage: 270 Mg/day, start time:
Oct 14, 2006), combined with:
  • Magmitt (330 Mg, Tid)
  • Magmitt (330 Mg, Tid)
  • Warfarin Sodium (3 Mg, Unk)
  • Warfarin Sodium (2 Mg, Unk)
  • Warfarin Sodium (1.5 Mg, Unk)
  • Warfarin Sodium (1 Mg, Unk)
  • Warfarin Sodium (1.5 Mg, Unk)
  • Warfarin Sodium (1.75 Mg, Unk)
and developed a serious reaction and side effect(s): International Normalised Ratio Increased, Prothrombin Time Prolonged after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Fastic treatment in female patients, resulting in International Normalised Ratio Increased side effect.
Fastic Side Effect Report#5131613-X
Prothrombin Time Prolonged
This report suggests a potential Fastic Prothrombin Time Prolonged side effect(s) that can have serious consequences. A 75-year-old female patient (weight: NA) from Japan was diagnosed with the following symptoms/conditions: diabetes mellitus and used Fastic (dosage: 270 Mg, Unk) starting
Jul 10, 2002. After starting Fastic the patient began experiencing various side effects, including: Prothrombin Time ProlongedAdditional drugs used concurrently:
  • Magmitt (330 Mg/day)
  • Warfarin Sodium (3 Mg, Unk)
  • Digoxin (0.25 Df, Unk)
  • Nitorol (40 Df, Unk)
  • Norvasc (5 Df, Unk)
Although Fastic demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Prothrombin Time Prolonged, may still occur.
Fastic Side Effect Report#5129850-3
Angina Pectoris
This Angina Pectoris problem was reported by a physician from Japan. A 75-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: diabetes mellitus. On
Feb 16, 2006 this consumer started treatment with Fastic (dosage: 90 Mg/day). The following drugs were being taken at the same time: NA. When using Fastic, the patient experienced the following unwanted symptoms/side effects: Angina PectorisThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Angina Pectoris, may become evident only after a product is in use by the general population.
Fastic Side Effect Report#5074145-X
Alanine Aminotransferase Increased, Anorexia, Aspartate Aminotransferase Increased, Blood Bilirubin Increased, Jaundice, Liver Disorder
This Alanine Aminotransferase Increased side effect was reported by a physician from Japan. A 83-year-old female patient (weight:NA) experienced the following symptoms/conditions: diabetes mellitus,osteoporosis,insomnia.The patient was prescribed Fastic (drug dosage: 270 Mg/day), which was initiated on NS. Concurrently used drugs:
  • Actonel (2.5 Mg/day)
  • Depas (0.5 Mg/day)
  • Platibit (1 Ug/day)
  • Prorenal (15 Ug/day)
  • Neurovitan
  • Horizon
  • Torsemide (4 Mg, Unk)
  • Glakay (30 Mg, Unk)
.After starting to take Fastic the consumer reported adverse symptoms, such as: Alanine Aminotransferase Increased, Anorexia, Aspartate Aminotransferase Increased, Blood Bilirubin Increased, Jaundice, Liver DisorderThese side effects may potentially be related to Fastic. The patient was hospitalized.
Fastic Side Effect Report#5039102-8
Anorexia, Blood Bilirubin Increased, Jaundice
This is a report of a 83-year-old female patient (weight: NA) from Japan, suffering from the following health symptoms/conditions: diabetes mellitus,osteoporosis,insomnia, who was treated with Fastic (dosage: 270 Mg/day, start time: NS), combined with:
  • Actonel (2.5 Mg/day)
  • Depas (0.5 Mg/day)
  • Platibit (1 Ug/day)
  • Prorenal (15 Ug/day)
  • Neurovitan
  • Horizon
  • Torsemide (4 Mg, Unk)
  • Glakay (30 Mg, Unk)
and developed a serious reaction and side effect(s): Anorexia, Blood Bilirubin Increased, Jaundice after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Fastic treatment in female patients, resulting in Anorexia side effect. The patient was hospitalized.
Fastic Side Effect Report#4970525-9
Diabetes Mellitus Inadequate Control, Glycosylated Haemoglobin Increased, Impaired Insulin Secretion, Insulin C-peptide Decreased
This report suggests a potential Fastic Diabetes Mellitus Inadequate Control side effect(s) that can have serious consequences. A 25-year-old male patient (weight: NA) from Japan was diagnosed with the following symptoms/conditions: diabetes mellitus insulin-dependent,constipation and used Fastic (dosage: 270 Mg/day) starting
Sep 13, 2004. After starting Fastic the patient began experiencing various side effects, including: Diabetes Mellitus Inadequate Control, Glycosylated Haemoglobin Increased, Impaired Insulin Secretion, Insulin C-peptide DecreasedAdditional drugs used concurrently:
  • Magnesium Oxide (1 G, Unk)
The patient was hospitalized. Although Fastic demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Diabetes Mellitus Inadequate Control, may still occur.
Fastic Side Effect Report#4930014-4
Diabetes Mellitus, Diabetes Mellitus Insulin-dependent, Glycosylated Haemoglobin Increased, Insulin C-peptide Decreased
This Diabetes Mellitus problem was reported by a physician from Japan. A 25-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: diabetes mellitus insulin-dependent,constipation. On
Sep 14, 2004 this consumer started treatment with Fastic (dosage: 270 Mg/day). The following drugs were being taken at the same time:
  • Magnesium Oxide (3 G, Unk)
When using Fastic, the patient experienced the following unwanted symptoms/side effects: Diabetes Mellitus, Diabetes Mellitus Insulin-dependent, Glycosylated Haemoglobin Increased, Insulin C-peptide DecreasedThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Diabetes Mellitus, may become evident only after a product is in use by the general population.
Fastic Side Effect Report#4902354-6
Acute Respiratory Distress Syndrome, Antinuclear Antibody Positive, Cough, Dyspnoea, Herpes Zoster, Hypoxia, Interstitial Lung Disease, Pneumonia
This Acute Respiratory Distress Syndrome side effect was reported by a physician from Japan. A 66-year-old female patient (weight:NA) experienced the following symptoms/conditions: diabetes mellitus.The patient was prescribed Fastic (drug dosage: 270 Mg/day), which was initiated on
Aug 19, 2002. Concurrently used drugs:
  • Daonil (3.75 Mg, Tid)
  • Starsis (Unk, Unk)
.After starting to take Fastic the consumer reported adverse symptoms, such as: Acute Respiratory Distress Syndrome, Antinuclear Antibody Positive, Cough, Dyspnoea, Herpes Zoster, Hypoxia, Interstitial Lung Disease, PneumoniaThese side effects may potentially be related to Fastic. The patient was hospitalized.
Fastic Side Effect Report#4894283-1
Acute Respiratory Distress Syndrome, Antinuclear Antibody Positive, Collagen Disorder, Cough, Deep Vein Thrombosis, Dyspnoea, Haemorrhagic Cerebral Infarction, Herpes Zoster, Hypoxia
This is a report of a 66-year-old female patient (weight: NA) from Japan, suffering from the following health symptoms/conditions: diabetes mellitus, who was treated with Fastic (dosage: 270 Mg/day, start time:
Aug 19, 2002), combined with:
  • Daonil (3.75 Mg, Tid)
  • Starsis (Unk, Unk)
and developed a serious reaction and side effect(s): Acute Respiratory Distress Syndrome, Antinuclear Antibody Positive, Collagen Disorder, Cough, Deep Vein Thrombosis, Dyspnoea, Haemorrhagic Cerebral Infarction, Herpes Zoster, Hypoxia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Fastic treatment in female patients, resulting in Acute Respiratory Distress Syndrome side effect. The patient was hospitalized.
Fastic Side Effect Report#4869212-7
Interstitial Lung Disease
This report suggests a potential Fastic Interstitial Lung Disease side effect(s) that can have serious consequences. A 66-year-old female patient (weight: NA) from Japan was diagnosed with the following symptoms/conditions: diabetes mellitus,bile duct stenosis and used Fastic (dosage: 270 Mg/day) starting
Jul 15, 2002. After starting Fastic the patient began experiencing various side effects, including: Interstitial Lung DiseaseAdditional drugs used concurrently:
  • Daonil (3.75 Mg/day)
The patient was hospitalized. Although Fastic demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Interstitial Lung Disease, may still occur.
Fastic Side Effect Report#4852528-8
Interstitial Lung Disease
This Interstitial Lung Disease problem was reported by a physician from Japan. A 66-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Jul 01, 2002 this consumer started treatment with Fastic (dosage: NA). The following drugs were being taken at the same time: NA. When using Fastic, the patient experienced the following unwanted symptoms/side effects: Interstitial Lung DiseaseAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Interstitial Lung Disease, may become evident only after a product is in use by the general population.
Fastic Side Effect Report#4844179-6
Interstitial Lung Disease
This Interstitial Lung Disease side effect was reported by a consumer or non-health professional from Japan. A 66-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Fastic (drug dosage: NA), which was initiated on
Jul 01, 2002. Concurrently used drugs: NA..After starting to take Fastic the consumer reported adverse symptoms, such as: Interstitial Lung DiseaseThese side effects may potentially be related to Fastic.
Fastic Side Effect Report#4825362-2
Blood Antidiuretic Hormone Increased, Blood Osmolarity Decreased, Convulsion, Depressed Level Of Consciousness, Dysarthria, Hallucination, Hyponatraemia, Inappropriate Antidiuretic Hormone Secretion, Lymphoma
This is a report of a 74-year-old male patient (weight: NA) from Japan, suffering from the following health symptoms/conditions: diabetes mellitus,hypertension, who was treated with Fastic (dosage: 90 Mg, Qd, start time:
Jan 29, 1997), combined with:
  • Blopress (8 Mg, Unk)
  • Calblock (16 Mg, Unk)
  • Almarl (20 Mg, Unk)
  • Lipitor (10 Mg, Unk)
  • Zaditen (4.14 Mg, Unk)
  • Atarax (25 Mg, Unk)
  • Rhythmy (2 Mg, Unk)
and developed a serious reaction and side effect(s): Blood Antidiuretic Hormone Increased, Blood Osmolarity Decreased, Convulsion, Depressed Level Of Consciousness, Dysarthria, Hallucination, Hyponatraemia, Inappropriate Antidiuretic Hormone Secretion, Lymphoma after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Fastic treatment in male patients, resulting in Blood Antidiuretic Hormone Increased side effect. The patient was hospitalized.


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The appearance of Fastic on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

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    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Fastic reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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    Side Effects reported to FDA: 38

    Fastic safety alerts: No

    Reported deaths: 1

    Reported hospitalizations: 27

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