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Fastic Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 38 

Bladder Cancer (7967163-2)
on Nov 22, 2011 Male from JAPAN , 61 years of age, was treated with Fastic (natelginide). Directly after, patient experienced the unwanted or unexpected Fastic side effects: bladder cancer. Fastic (natelginide) dosage: N/A.
Associated medications used:
  • Actos (15 Mg (15 Mg,1 In 1 D) Per Oral ; 30 Mg (30 Mg, 1 In 1 D) Per Oral)
  • Actos (15 Mg (15 Mg,1 In 1 D) Per Oral ; 30 Mg (30 Mg, 1 In 1 D) Per Oral)
  • Diovan
  • Lantus
  • Aspirin
  • Crestor
  • Norvasc
  • Novolog
Patient was hospitalized.

Bladder Cancer, Prostate Cancer (7593626-8)
Patient was taking Fastic (nateglinide). Patient felt the following Fastic side effects: bladder cancer, prostate cancer on Jun 13, 2011 from JAPAN Additional patient health information: Male , 68 years of age, . Fastic (nateglinide) dosage: N/A.
Multiple prescriptions taken:
  • Basen (voglibose)
  • Takeperon (lansoprazole)
  • Actos (15 Mg (15 Mg, 1 D) Per Oral,)
Patient was hospitalized.

Liver Disorder, Glycosylated Haemoglobin Increased, Blood Glucose Increased (7409963-3)
Adverse event was reported on Mar 25, 2011 by a Male taking Fastic (Dosage: 180 Mg, Qd) . Location: JAPAN , 38 years of age, After Fastic was administered, patient encountered several Fastic side effects: liver disorder, glycosylated haemoglobin increased, blood glucose increased.
Multiple concurrent drugs taken:
  • Metformin Hcl (500 Mg, Qd)
  • Actos (30 Mg, Qd)


Hypokalaemia, Oedema Peripheral, Decreased Appetite, Rash, Gastric Ulcer, Stomatitis, Constipation, Aspartate Aminotransferase Increased, Pruritus (7331612-3)
on Feb 16, 2011 Female from JAPAN , 70 years of age, weighting 105.8 lb, was treated with Fastic. Directly after, patient experienced the unwanted or unexpected Fastic side effects: hypokalaemia, oedema peripheral, decreased appetite, rash, gastric ulcer, stomatitis, constipation, aspartate aminotransferase increased, pruritus. Fastic dosage: Daily Dose 270 Mg.
Associated medications used:
  • Tagamet (Daily Dose 800 Mg)
  • Sorafenib (raf Kinase Inhibitor) (Daily Dose 400 Mg)
  • Sorafenib (raf Kinase Inhibitor) (Daily Dose 400 Mg)
  • Cortril (Daily Dose 10.5 Mg)
  • Sorafenib (raf Kinase Inhibitor) (Daily Dose 400 Mg)
  • Sorafenib (raf Kinase Inhibitor) (Daily Dose 800 Mg)
Patient was hospitalized.


Interstitial Lung Disease, Renal Impairment, Respiratory Failure, Urine Output Decreased, Pulmonary Oedema, Cardiac Arrest (7241716-1)
on Jan 17, 2011 Male from JAPAN , weighting 136.7 lb, was diagnosed with
  • diabetes mellitus
and was treated with Fastic. Patient felt the following Fastic side effects: interstitial lung disease, renal impairment, respiratory failure, urine output decreased, pulmonary oedema, cardiac arrest. Fastic dosage: 90 Mg, Unk.
Multiple prescriptions taken:
  • Ceftriaxone Sodium (Unk)
  • Diovan (40 Mg, Qd)
  • Takepron (15 Mg, Unk)
  • Diart (30 Mg, Unk)
  • Minocycline Hydrochloride (100 Mg)
  • Allopurinol (100 Mg, Unk)
  • Ulcerlmin (3 G, Unk)
Patient was hospitalized.

Hypoglycaemia, Infection (6717923-0)
Patient was taking Fastic. After Fastic was administered, patient encountered several Fastic side effects: hypoglycaemia, infection on Apr 27, 2010 from JAPAN Additional patient health information: Male , 66 years of age, was diagnosed with
  • diabetes mellitus
  • infection
and. Fastic dosage: 90 Mg Daily.
Multiple concurrent drugs taken:
  • Cravit (Unk)
  • Allopurinol
  • Hornel
  • Mucosta
  • Norvasc
  • Basen
  • Epadel
Patient was hospitalized.

Atrioventricular Block Complete (6361582-6)
Adverse event was reported on Sep 05, 2009 by a Male taking Fastic (Dosage: 90 Mg/day) was diagnosed with
  • diabetes mellitus
and. Location: JAPAN , 80 years of age, Directly after, patient experienced the unwanted or unexpected Fastic side effects: atrioventricular block complete.
Associated medications used:
  • Famotidine D
  • Voglibose
  • Allorine (100 Mg, Unk)
Patient was hospitalized.

Liver Disorder (6255124-3)
on Jun 18, 2009 Male from JAPAN , 39 years of age, was diagnosed with
  • type 2 diabetes mellitus
and was treated with Fastic. Patient felt the following Fastic side effects: liver disorder. Fastic dosage: 270 Mg/day.
Multiple prescriptions taken:
  • Melbin (500 Mg, Unk)


Blood Creatinine Increased, Blood Glucose Increased, Blood Lactate Dehydrogenase Increased, Blood Potassium Increased, Blood Urea Increased, C-reactive Protein Increased, Gamma-glutamyltransferase Increased, Lymphocyte Percentage Increased, Platelet Count Increased (5659488-0)
on Mar 07, 2008 Male from JAPAN , 60 years of age, was diagnosed with
  • diabetes mellitus
and was treated with Fastic. After Fastic was administered, patient encountered several Fastic side effects: blood creatinine increased, blood glucose increased, blood lactate dehydrogenase increased, blood potassium increased, blood urea increased, c-reactive protein increased, gamma-glutamyltransferase increased, lymphocyte percentage increased, platelet count increased. Fastic dosage: 90 Mg/day.
Multiple concurrent drugs taken:
  • Starsis (270 Mg/day)
  • Basen (0.6 Mg/day)
  • Melbin (500 Mg, Unk)
  • Glycoran (750 Mg, Unk)
  • Risumic (Unk, Unk)
  • Risumic
Patient was hospitalized.

Depression, Hypoglycaemia (5317637-8)
Patient was taking Fastic. Directly after, patient experienced the unwanted or unexpected Fastic side effects: depression, hypoglycaemia on Apr 24, 2007 from JAPAN Additional patient health information: Female , 87 years of age, was diagnosed with
  • diabetes mellitus
and. Fastic dosage: N/A.
Associated medications used:
  • Minocycline Hcl


Interstitial Lung Disease (5237847-8)
Adverse event was reported on Feb 02, 2007 by a Male taking Fastic (Dosage: 180 Mg/day) was diagnosed with
  • diabetes mellitus
and. Location: JAPAN , 71 years of age, Patient felt the following Fastic side effects: interstitial lung disease.
Multiple prescriptions taken:
  • Olmetec (20 Mg/day)
  • Mobic (10 Mg/day)
  • Lipidil (40 Mg/day)
  • Artist (10 Mg, Unk)
  • Calblock (16 Mg, Unk)
Patient was hospitalized.

Interstitial Lung Disease (5192730-1)
on Dec 19, 2006 Male from JAPAN , 71 years of age, was diagnosed with
  • diabetes mellitus
and was treated with Fastic. After Fastic was administered, patient encountered several Fastic side effects: interstitial lung disease. Fastic dosage: 180 Mg/day.
Multiple concurrent drugs taken:
  • Olmetec (20 Mg/day)
  • Mobic (10 Mg/day)
  • Lipidil (40 Mg/day)
  • Artist (10 Mg, Unk)
  • Calblock (16 Mg, Unk)
Patient was hospitalized.

International Normalised Ratio Increased, Prothrombin Time Prolonged (5141277-7)
on Oct 12, 2006 Female from JAPAN , 75 years of age, was diagnosed with
  • diabetes mellitus
and was treated with Fastic. Directly after, patient experienced the unwanted or unexpected Fastic side effects: international normalised ratio increased, prothrombin time prolonged. Fastic dosage: 270 Mg/day.
Associated medications used:
  • Magmitt (330 Mg, Tid)
  • Magmitt (330 Mg, Tid)
  • Warfarin Sodium (3 Mg, Unk)
  • Warfarin Sodium (2 Mg, Unk)
  • Warfarin Sodium (1.5 Mg, Unk)
  • Warfarin Sodium (1 Mg, Unk)
  • Warfarin Sodium (1.5 Mg, Unk)
  • Warfarin Sodium (1.75 Mg, Unk)


Prothrombin Time Prolonged (5131613-X)
Patient was taking Fastic. Patient felt the following Fastic side effects: prothrombin time prolonged on Oct 12, 2006 from JAPAN Additional patient health information: Female , 75 years of age, was diagnosed with
  • diabetes mellitus
and. Fastic dosage: 270 Mg, Unk.
Multiple prescriptions taken:
  • Magmitt (330 Mg/day)
  • Warfarin Sodium (3 Mg, Unk)
  • Digoxin (0.25 Df, Unk)
  • Nitorol (40 Df, Unk)
  • Norvasc (5 Df, Unk)


Angina Pectoris (5129850-3)
Adverse event was reported on Sep 06, 2006 by a Male taking Fastic (Dosage: 90 Mg/day) was diagnosed with
  • diabetes mellitus
and. Location: JAPAN , 75 years of age, After Fastic was administered, patient encountered several Fastic side effects: angina pectoris. Patient was hospitalized.

Alanine Aminotransferase Increased, Anorexia, Aspartate Aminotransferase Increased, Blood Bilirubin Increased, Jaundice, Liver Disorder (5074145-X)
on Jun 22, 2006 Female from JAPAN , 83 years of age, was diagnosed with
  • diabetes mellitus
  • osteoporosis
  • insomnia
and was treated with Fastic. Directly after, patient experienced the unwanted or unexpected Fastic side effects: alanine aminotransferase increased, anorexia, aspartate aminotransferase increased, blood bilirubin increased, jaundice, liver disorder. Fastic dosage: 270 Mg/day.
Associated medications used:
  • Actonel (2.5 Mg/day)
  • Depas (0.5 Mg/day)
  • Platibit (1 Ug/day)
  • Prorenal (15 Ug/day)
  • Neurovitan
  • Horizon
  • Torsemide (4 Mg, Unk)
  • Glakay (30 Mg, Unk)
Patient was hospitalized.

Anorexia, Blood Bilirubin Increased, Jaundice (5039102-8)
on Jun 22, 2006 Female from JAPAN , 83 years of age, was diagnosed with
  • diabetes mellitus
  • osteoporosis
  • insomnia
and was treated with Fastic. Patient felt the following Fastic side effects: anorexia, blood bilirubin increased, jaundice. Fastic dosage: 270 Mg/day.
Multiple prescriptions taken:
  • Actonel (2.5 Mg/day)
  • Depas (0.5 Mg/day)
  • Platibit (1 Ug/day)
  • Prorenal (15 Ug/day)
  • Neurovitan
  • Horizon
  • Torsemide (4 Mg, Unk)
  • Glakay (30 Mg, Unk)
Patient was hospitalized.

Diabetes Mellitus Inadequate Control, Glycosylated Haemoglobin Increased, Impaired Insulin Secretion, Insulin C-peptide Decreased (4970525-9)
Patient was taking Fastic. After Fastic was administered, patient encountered several Fastic side effects: diabetes mellitus inadequate control, glycosylated haemoglobin increased, impaired insulin secretion, insulin c-peptide decreased on Feb 20, 2006 from JAPAN Additional patient health information: Male , 25 years of age, was diagnosed with
  • diabetes mellitus insulin-dependent
  • constipation
and. Fastic dosage: 270 Mg/day.
Multiple concurrent drugs taken:
  • Magnesium Oxide (1 G, Unk)
Patient was hospitalized.

Diabetes Mellitus, Diabetes Mellitus Insulin-dependent, Glycosylated Haemoglobin Increased, Insulin C-peptide Decreased (4930014-4)
Adverse event was reported on Feb 20, 2006 by a Male taking Fastic (Dosage: 270 Mg/day) was diagnosed with
  • diabetes mellitus insulin-dependent
  • constipation
and. Location: JAPAN , 25 years of age, Directly after, patient experienced the unwanted or unexpected Fastic side effects: diabetes mellitus, diabetes mellitus insulin-dependent, glycosylated haemoglobin increased, insulin c-peptide decreased.
Associated medications used:
  • Magnesium Oxide (3 G, Unk)
Patient was hospitalized.

Acute Respiratory Distress Syndrome, Antinuclear Antibody Positive, Cough, Dyspnoea, Herpes Zoster, Hypoxia, Interstitial Lung Disease, Pneumonia (4902354-6)
on Nov 30, 2005 Female from JAPAN , 66 years of age, was diagnosed with
  • diabetes mellitus
and was treated with Fastic. Patient felt the following Fastic side effects: acute respiratory distress syndrome, antinuclear antibody positive, cough, dyspnoea, herpes zoster, hypoxia, interstitial lung disease, pneumonia. Fastic dosage: 270 Mg/day.
Multiple prescriptions taken:
  • Daonil (3.75 Mg, Tid)
  • Starsis (Unk, Unk)
Patient was hospitalized.

Acute Respiratory Distress Syndrome, Antinuclear Antibody Positive, Collagen Disorder, Cough, Deep Vein Thrombosis, Dyspnoea, Haemorrhagic Cerebral Infarction, Herpes Zoster, Hypoxia (4894283-1)
on Nov 30, 2005 Female from JAPAN , 66 years of age, was diagnosed with
  • diabetes mellitus
and was treated with Fastic. After Fastic was administered, patient encountered several Fastic side effects: acute respiratory distress syndrome, antinuclear antibody positive, collagen disorder, cough, deep vein thrombosis, dyspnoea, haemorrhagic cerebral infarction, herpes zoster, hypoxia. Fastic dosage: 270 Mg/day.
Multiple concurrent drugs taken:
  • Daonil (3.75 Mg, Tid)
  • Starsis (Unk, Unk)
Patient was hospitalized.

Interstitial Lung Disease (4869212-7)
Patient was taking Fastic. Directly after, patient experienced the unwanted or unexpected Fastic side effects: interstitial lung disease on Nov 30, 2005 from JAPAN Additional patient health information: Female , 66 years of age, was diagnosed with
  • diabetes mellitus
  • bile duct stenosis
and. Fastic dosage: 270 Mg/day.
Associated medications used:
  • Daonil (3.75 Mg/day)
Patient was hospitalized.

Interstitial Lung Disease (4852528-8)
Adverse event was reported on Nov 30, 2005 by a Female taking Fastic (Dosage: N/A) . Location: JAPAN , 66 years of age, Patient felt the following Fastic side effects: interstitial lung disease.

Interstitial Lung Disease (4844179-6)
on Nov 30, 2005 Female from JAPAN , 66 years of age, was treated with Fastic. After Fastic was administered, patient encountered several Fastic side effects: interstitial lung disease. Fastic dosage: N/A.

Blood Antidiuretic Hormone Increased, Blood Osmolarity Decreased, Convulsion, Depressed Level Of Consciousness, Dysarthria, Hallucination, Hyponatraemia, Inappropriate Antidiuretic Hormone Secretion, Lymphoma (4825362-2)
on Jul 01, 2005 Male from JAPAN , 74 years of age, was diagnosed with
  • diabetes mellitus
  • hypertension
and was treated with Fastic. Directly after, patient experienced the unwanted or unexpected Fastic side effects: blood antidiuretic hormone increased, blood osmolarity decreased, convulsion, depressed level of consciousness, dysarthria, hallucination, hyponatraemia, inappropriate antidiuretic hormone secretion, lymphoma. Fastic dosage: 90 Mg, Qd.
Associated medications used:
  • Blopress (8 Mg, Unk)
  • Calblock (16 Mg, Unk)
  • Almarl (20 Mg, Unk)
  • Lipitor (10 Mg, Unk)
  • Zaditen (4.14 Mg, Unk)
  • Atarax (25 Mg, Unk)
  • Rhythmy (2 Mg, Unk)
Patient was hospitalized.

Showing 1-25 of 38 

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Fastic Information

More About Fastic

Side Effects reported to FDA: 38. View Fastic Adverse Reports

Fastic safety alerts: No

Reported deaths: 1

Reported hospitalizations: 25

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