From simple mix-ups to fatal overdoses, medication mistakes happen, on average, once a day to every hospital patient, a new report says. Nationwide, at least 1.5 million people annually are harmed from drug errors, more than half of them in nursing homes, said the Institute of Medicine report, released yesterday.
Many Unfavorable Drug Studies Aren’t Published. Nearly a third of antidepressant drug studies are never published in the medical literature, and nearly all of those happen to show that the drug being tests failed to work.
Only Drugs That are Safe Should be put on the Market. Drug developers are just beginning to come to grips with recent FDA oversight reforms and how they will affect drug safety. But, it appears that industry and consumer advocates are not together on how well the overhaul will be able to prevent future drug safety scandals.

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Fosphenytoin Safety Reports submitted to FDA

Total Fosphenytoin reports: 13.
Fosphenytoin FDA safety alerts: No.
   Reported hospitalizations: 8.
Take Fosphenytoin Side Effects Survey or Share Your Fosphenytoin Story.
Reported Fosphenytoin Side Effects: hypotension, bradycardia, overdose, hyperthermia, choreoathetosis, convulsion, thrombocytopenia, leukopenia, haemoglobin decreased, unresponsive to stimuli, sensory loss.
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Fosphenytoin Side Effects Report #5302956-1
Pharmacist from UNITED STATES reported FOSPHENYTOIN problem on Apr 17, 2007. Female patient, weighting 226.0 lb, was diagnosed with status epilepticus and was treated with FOSPHENYTOIN. After drug was administered, patient experienced the following problems/side effects: bradycardia, ventricular tachycardia. FOSPHENYTOIN dosage: 1000MG LOADING DOSE IV BOLUS. During the same period patient was treated with LEXAPRO, SYNTHROID, LAMICTAL, INDERAL, TOPAMAX, VALIUM, OXYCODONE, TYLENOL. Patient recovered.

Fosphenytoin Side Effects Report #5343937-1
FOSPHENYTOIN problem was reported by a Pharmacist from UNITED STATES on May 31, 2007. Female patient, 56 years of age, was diagnosed with convulsion and was treated with FOSPHENYTOIN. After drug was administered, patient experienced the following problems/side effects: hypotension. FOSPHENYTOIN dosage: 1500 MG ONCE IV DRIP. Patient recovered.

Fosphenytoin Side Effects Report #5359366-0
Health Professional from FRANCE reported FOSPHENYTOIN problem on June 04, 2007. Female patient, child 12 years of age, was treated with FOSPHENYTOIN. After drug was administered, patient experienced the following problems/side effects: haemoglobin decreased, leukopenia, thrombocytopenia. FOSPHENYTOIN dosage: unknown. During the same period patient was treated with DEPAKENE, DIAZEPAM, KEPPRA, CALCIFORTE, SUCRALFATE. Patient was hospitalized. Patient recovered.

Fosphenytoin Side Effects Report #5071545-9
FOSPHENYTOIN problem was reported by a Pharmacist from UNITED STATES on Aug 03, 2006. Male patient, 72 years of age, weighting 138.9 lb, was diagnosed with grand mal convulsion and was treated with FOSPHENYTOIN. After drug was administered, patient experienced the following problems/side effects: bradycardia, hypotension. FOSPHENYTOIN dosage: 900 MG IVPB ONCE. Patient was hospitalized. Patient recovered.

Fosphenytoin Side Effects Report #5081396-7
Pharmacist from UNITED STATES reported FOSPHENYTOIN problem on Aug 14, 2006. Male patient, 26 years of age, was treated with FOSPHENYTOIN. After drug was administered, patient experienced the following problems/side effects: convulsion, dizziness, tremor, visual disturbance. FOSPHENYTOIN dosage: unknown. Patient was hospitalized. Patient recovered.

Fosphenytoin Side Effects Report #5103802-1
FOSPHENYTOIN problem was reported by a Physician from FRANCE on Aug 29, 2006. Male patient, child 7 years of age, was diagnosed with epilepsy and was treated with FOSPHENYTOIN. After drug was administered, patient experienced the following problems/side effects: choreoathetosis, gait disturbance, hyperthermia, overdose. FOSPHENYTOIN dosage: 300 MG 9100 MG, 3 IN 1 D) INTRAMUSCULAR. During the same period patient was treated with STIRIPENTOL, TOPIRAMATE, CLOBAZAM. Patient was hospitalized. Patient recovered.

Fosphenytoin Side Effects Report #5106304-1
Consumer or non-health professional from UNITED KINGDOM reported FOSPHENYTOIN problem on Aug 30, 2006. Female patient, child 8 years of age, was diagnosed with epilepsy and was treated with FOSPHENYTOIN. After drug was administered, patient experienced the following problems/side effects: epilepsy. FOSPHENYTOIN dosage: unknown. Patient was hospitalized. Patient recovered.

Fosphenytoin Side Effects Report #5109786-4
FOSPHENYTOIN problem was reported by a Physician from FRANCE on Aug 29, 2006. Male patient, child 7 years of age, was diagnosed with epilepsy and was treated with FOSPHENYTOIN. After drug was administered, patient experienced the following problems/side effects: apnoea, choreoathetosis, febrile convulsion, hyperthermia, overdose, status epilepticus. FOSPHENYTOIN dosage: 300 MG (100 MG, 3 IN 1 D), INTRAMUSCULAR. During the same period patient was treated with STIRIPENTOL, TOPIRAMATE, CLOBAZAM. Patient was hospitalized. Patient recovered.

Fosphenytoin Side Effects Report #5143493-7
Pharmacist from UNITED STATES reported FOSPHENYTOIN problem on Nov 01, 2006. Male patient, 47 years of age, weighting 220.5 lb, was diagnosed with convulsion prophylaxis and was treated with FOSPHENYTOIN. After drug was administered, patient experienced the following problems/side effects: bradycardia, hypotension, resuscitation. FOSPHENYTOIN dosage: 1500MG ONCE IV DRIP. During the same period patient was treated with PHENYTOIN CAP, AMIODARONE, NOREPINEPHRINE BITARTRATE, VASOPRESSIN, MIDAZOLAM, CHLORIDE, PIPERACILLIN AND TAZOBACTAM. Patient recovered.

Fosphenytoin Side Effects Report #5186332-0
FOSPHENYTOIN problem was reported by a Health Professional from FRANCE on Dec 01, 2006. Female patient, child 12 years of age, was treated with FOSPHENYTOIN. After drug was administered, patient experienced the following problems/side effects: haemoglobin decreased, leukopenia, petechiae, thrombocytopenia. FOSPHENYTOIN dosage: unknown. During the same period patient was treated with DEPAKENE, DIAZEPAM, KEPPRA, CALCIFORTE, ULCAR. Patient was hospitalized. Patient recovered.

Fosphenytoin Side Effects Report #5427416-9
Pharmacist from UNITED STATES reported FOSPHENYTOIN problem on Aug 24, 2007. Female patient, 79 years of age, weighting 172.0 lb, was diagnosed with altered state of consciousness, convulsion and was treated with FOSPHENYTOIN. After drug was administered, patient experienced the following problems/side effects: blood pressure systolic decreased, cardio-respiratory arrest, electromechanical dissociation. FOSPHENYTOIN dosage: 1000MG 1X ONLY 1V BOLUS. Patient recovered.

Fosphenytoin Side Effects Report #5448220-1
FOSPHENYTOIN problem was reported by a Pharmacist from UNITED STATES on Sept 06, 2007. Female patient, 80 years of age, was diagnosed with convulsion and was treated with FOSPHENYTOIN. After drug was administered, patient experienced the following problems/side effects: hepatitis. FOSPHENYTOIN dosage: unknown. Patient was hospitalized and became disabled. Patient recovered.

Fosphenytoin Side Effects Report #5455656-1
Pharmacist from UNITED STATES reported FOSPHENYTOIN problem on Sept 13, 2007. Female patient, 60 years of age, weighting 159.8 lb, was diagnosed with convulsion and was treated with FOSPHENYTOIN. After drug was administered, patient experienced the following problems/side effects: convulsion, infusion related reaction, no therapeutic response, sensory loss, unresponsive to stimuli. FOSPHENYTOIN dosage: 1000MG ONCE IV BOLUS. During the same period patient was treated with MORPHINE, HYDRALAZINE, NIMOTOP, CEFAZOLIN, PANTOPRAZOLE, DEXAMETHASONE, NS WITH KCL. Patient recovered.

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