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Review Gleevec Safety Reports submitted to FDA

Total Gleevec reports: 1149.
Gleevec FDA safety alerts: 2006 .
Reported deaths: 268    Reported hospitalizations: 497.
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FDA Reported Gleevec Side Effects: oedema peripheral, nausea, cardiac failure congestive, haemoglobin decreased, fatigue, malignant neoplasm progression, blood creatinine increased, pyrexia, dyspnoea exertional, dyspnoea, asthenia.
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Gleevec Side Effects Report #5441482-6
Physician from UNITED STATES reported GLEEVEC problem on Aug 30, 2007. Female patient was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: follicle centre lymphoma, follicular grade i, ii, iii. GLEEVEC dosage: 400 MG, QD. Patient recovered.

Gleevec Side Effects Report #5443005-4
GLEEVEC problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 27, 2007. Female patient, 66 years of age, was diagnosed with chronic myeloid leukaemia, anxiety disorder, hypertension, hypothyroidism and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: abasia, abnormal behaviour, anaemia, asphyxia, blood potassium abnormal, cardiac failure congestive, cardiac valve disease, costochondritis, diarrhoea. GLEEVEC dosage: 400 MG, QD. During the same period patient was treated with NEXIUM, XANAX, METOPROLOL SUCCINATE, SYNTHROID, HYDROXYUREA, DIOVAN HCT, COREG, NAPROXEN DR. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5443022-4
Consumer or non-health professional from UNITED STATES reported GLEEVEC problem on Aug 27, 2007. Male patient was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: nausea, oedema peripheral, suicidal ideation, swelling face. GLEEVEC dosage: 200 MG, BID. Patient recovered.

Gleevec Side Effects Report #5443049-2
GLEEVEC problem was reported by a Physician from INDIA on Aug 30, 2007. Male patient, 58 years of age, weighting 130.1 lb, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: acanthosis, breast tenderness, dermatitis exfoliative, eosinophilia, erythema, lymphadenopathy, lymphocytic infiltration, oedema peripheral, parakeratosis. GLEEVEC dosage: 400 MG, QD. Patient recovered.

Gleevec Side Effects Report #5444390-X
Consumer or non-health professional from FRANCE reported GLEEVEC problem on Aug 31, 2007. Male patient was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: adenocarcinoma, prostate cancer. GLEEVEC dosage: 400 MG DAILY. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5445891-0
GLEEVEC problem was reported by a Consumer or non-health professional from UNITED STATES on Sept 05, 2007. Female patient, 80 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: asthenia, back pain, blast crisis in myelogenous leukaemia, cardiac disorder, cardiac failure, cerebrovascular accident, colonoscopy abnormal, coronary artery disease, diabetes mellitus. GLEEVEC dosage: unknown. During the same period patient was treated with INSULIN. Patient was hospitalized. Patient died on 07/18/2007.

Gleevec Side Effects Report #5445893-4
Physician from CYPRUS reported GLEEVEC problem on Aug 31, 2007. Female patient, 24 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: chromosome analysis abnormal, myelodysplastic syndrome. GLEEVEC dosage: 400 MG / DAY. Patient recovered.

Gleevec Side Effects Report #5447175-3
GLEEVEC problem was reported by a Consumer or non-health professional from UNITED STATES on Sept 04, 2007. Male patient was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: nausea, oedema peripheral, suicidal ideation, swelling face. GLEEVEC dosage: 200 MG, BID. Patient recovered.

Gleevec Side Effects Report #5447209-6
Consumer or non-health professional from TAIWAN, PROVINCE OF CHINA reported GLEEVEC problem on Sept 05, 2007. Female patient, 68 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: cerebral haemorrhage, pneumonia, road traffic accident, septic shock. GLEEVEC dosage: 400 MG/D. Patient was hospitalized. Patient died on 07/30/2007.

Gleevec Side Effects Report #5447660-4
GLEEVEC problem was reported by a Health Professional from UNITED STATES on Sept 06, 2007. Female patient, weighting 144.4 lb, was diagnosed with breast cancer metastatic and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: pleural effusion, pneumonia. GLEEVEC dosage: 400 MG BID PO. During the same period patient was treated with TAXOL. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5448254-7
Physician from UNITED STATES reported GLEEVEC problem on Sept 04, 2007. Male patient, 29 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: diplopia, eyelid ptosis, iiird nerve paralysis, intubation, leukocytosis, mastication disorder, muscular weakness, myasthenia gravis, tensilon test abnormal. GLEEVEC dosage: 400 MG, QD. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5448255-9
GLEEVEC problem was reported by a Physician from JAPAN on Sept 04, 2007. Male patient, 18 years of age, weighting 132.3 lb, was diagnosed with acute lymphocytic leukaemia, disseminated intravascular coagulation, hepatic function abnormal and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: pneumatosis intestinalis. GLEEVEC dosage: 600 MG/D. During the same period patient was treated with DAUNORUBICIN, PREDONINE, ENDOXAN, ONCOVIN, STEROIDS NOS, REMINARON, MINOPHAGEN C. Patient recovered.

Gleevec Side Effects Report #5448259-6
Physician from UNITED KINGDOM reported GLEEVEC problem on Sept 05, 2007. Female patient, 81 years of age, was diagnosed with chronic myeloid leukaemia, hypertension, aortic valve incompetence, transient ischaemic attack, atrial flutter, nausea and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: cardiac arrest, convulsion, hypertension, nausea, respiratory arrest. GLEEVEC dosage: 400MG. During the same period patient was treated with DOXAZOSIN MESYLATE, FRUSEMIDE, ASPIRIN, ALLOPURINOL, AMIODARONE, BISOPROLOL, CYCLIZINE. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5448274-2
GLEEVEC problem was reported by a Health Professional from UNITED STATES on Aug 31, 2007. Male patient, 52 years of age, was diagnosed with chronic myeloid leukaemia, hypertension, hypercholesterolaemia, gastrooesophageal reflux disease, depression, anxiety, muscle spasms, headache and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: arthralgia, arthropod bite, blood count abnormal, hyperglycaemia, pyrexia, rash. GLEEVEC dosage: 200MG -300 MG, QD. During the same period patient was treated with ALTACE, ZOCOR, NEXIUM, LEXAPRO, XANAX, QUININE, AMITRIPTYLINE. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5448288-2
Physician from JAPAN reported GLEEVEC problem on Sept 04, 2007. Female patient, 56 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: blood sodium decreased, oedema, weight increased. GLEEVEC dosage: 600 MG/D. During the same period patient was treated with VINCRISTINE, CYCLOPHOSPHAMIDE, DAUNORUBICIN. Patient recovered.

Gleevec Side Effects Report #5448289-4
GLEEVEC problem was reported by a Consumer or non-health professional from CANADA on Sept 04, 2007. Female patient, 18 years of age, weighting 183.0 lb, was diagnosed with chronic myeloid leukaemia, white blood cell count, osteomyelitis, deep vein thrombosis and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: leukostasis, placental disorder, premature labour, white blood cell count increased. GLEEVEC dosage: 400 MG, QD. During the same period patient was treated with INTERFERON, HYDROXYUREA, CEFTRIAXONE, FRAGMIN. Patient recovered.

Gleevec Side Effects Report #5448292-4
Consumer or non-health professional from SWITZERLAND reported GLEEVEC problem on Aug 30, 2007. Male patient, 59 years of age, was diagnosed with gastrointestinal stromal tumour and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: asthenia, blood creatine phosphokinase increased, blood creatinine increased, hypophosphataemia, hypotension, muscle atrophy, muscular weakness, orthostatic hypotension, pallanaesthesia. GLEEVEC dosage: 400 TO 800 MG/D. Patient recovered.

Gleevec Side Effects Report #5450825-9
GLEEVEC problem was reported by a Physician from GERMANY on Sept 05, 2007. Male patient, weighting 180.8 lb, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: blood creatine phosphokinase increased, myalgia, myositis. GLEEVEC dosage: 400 MG, QD. Patient recovered.

Gleevec Side Effects Report #5450836-3
Physician from UNITED STATES reported GLEEVEC problem on Sept 07, 2007. Female patient, 62 years of age, was diagnosed with chronic myeloid leukaemia, hypertension, pain and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: blood pressure fluctuation, hypoperfusion, optic ischaemic neuropathy. GLEEVEC dosage: 400 MG, QD. During the same period patient was treated with ATENOLOL, DYAZIDE, DARVOCET. Patient recovered.

Gleevec Side Effects Report #5450853-3
GLEEVEC problem was reported by a Physician from CYPRUS on Aug 31, 2007. Male patient, 54 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: breast adenoma. GLEEVEC dosage: unknown. Patient recovered.

Gleevec Side Effects Report #5450867-3
Consumer or non-health professional from UNITED KINGDOM reported GLEEVEC problem on Sept 06, 2007. Female patient was diagnosed with chronic myeloid leukaemia, infection and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: abnormal dreams, dizziness, infection, nausea, vomiting. GLEEVEC dosage: 400 MG, QD. During the same period patient was treated with OFLOXACIN, METRONIDAZOLE. Patient recovered.

Gleevec Side Effects Report #5451283-0
GLEEVEC problem was reported by a Pharmacist from JAPAN on Sept 05, 2007. Male patient, 51 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: leukoencephalomyelitis, progressive multifocal leukoencephalopathy. GLEEVEC dosage: 400 MG/D. During the same period patient was treated with NEORAL, PREDNISOLONE. Patient recovered.

Gleevec Side Effects Report #5455021-7
Physician from JAPAN reported GLEEVEC problem on Sept 07, 2007. Female patient, child 10 years of age, weighting 74.96 lb, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: anaemia, aplasia pure red cell, blood creatinine abnormal, bone pain, creatinine renal clearance, haematocrit decreased, haemoglobin decreased, hypercalcaemia, hyponatraemia. GLEEVEC dosage: 100 MG/D. Patient recovered.

Gleevec Side Effects Report #5455704-9
GLEEVEC problem was reported by a Physician from CANADA on Aug 23, 2007. Female patient was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: premature baby. GLEEVEC dosage: unknown. Patient recovered.

Gleevec Side Effects Report #5459812-8
Consumer or non-health professional from JAPAN reported GLEEVEC problem on Sept 11, 2007. Female patient, 67 years of age, was diagnosed with gastrointestinal stromal tumour and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: haemorrhage, oesophagectomy, oesophagoenterostomy, rash, wound secretion. GLEEVEC dosage: unknown. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5459820-7
GLEEVEC problem was reported by a Physician from UNITED STATES on Sept 10, 2007. Male patient, child 8 years of age, was diagnosed with diffuse large b-cell lymphoma stage iii and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: eye pain, optic neuritis, papilloedema, retinal vein thrombosis. GLEEVEC dosage: 300 MG, QD. During the same period patient was treated with ASPARAGINASE. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5461140-1
Physician from UNITED STATES reported GLEEVEC problem on Sept 13, 2007. Male patient was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation. GLEEVEC dosage: 400 MG, QD. Patient recovered.

Gleevec Side Effects Report #5463949-7
GLEEVEC problem was reported by a Physician from JAPAN on Sept 14, 2007. Female patient, 34 years of age, weighting 105.8 lb, was diagnosed with chronic myeloid leukaemia, constipation and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: abdominal pain, normal newborn, threatened labour, vomiting. GLEEVEC dosage: 400 MG/D. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5463958-8
Physician from SPAIN reported GLEEVEC problem on Sept 14, 2007. Male patient was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: thyroid cancer. GLEEVEC dosage: 100 MG. Patient recovered.

Gleevec Side Effects Report #5464242-9
GLEEVEC problem was reported by a Physician from UNITED STATES on Sept 13, 2007. Male patient, 56 years of age, weighting 184.0 lb, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aldolase increased, blood creatine phosphokinase increased, blood lactate dehydrogenase increased, muscle disorder, myalgia, myositis, neuropathy, synovial cyst. GLEEVEC dosage: 400 MG, QD. Patient recovered.

Gleevec Side Effects Report #5465208-5
Consumer or non-health professional from JAPAN reported GLEEVEC problem on Sept 19, 2007. Female patient, 62 years of age, was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: nausea. GLEEVEC dosage: unknown. Patient died.

Gleevec Side Effects Report #5465215-2
GLEEVEC problem was reported by a Physician from FRANCE on Sept 18, 2007. Female patient, 68 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: breast cancer. GLEEVEC dosage: unknown. Patient recovered.

Gleevec Side Effects Report #5465860-4
Consumer or non-health professional from CANADA reported GLEEVEC problem on Sept 17, 2007. Male patient, 61 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: cardiac disorder, hyperkalaemia, pulmonary oedema. GLEEVEC dosage: unknown. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5466611-X
GLEEVEC problem was reported by a Physician from AUSTRALIA on Sept 18, 2007. Female patient was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: abdominal pain, colonoscopy normal, irritable bowel syndrome. GLEEVEC dosage: 400MG. Patient recovered.

Gleevec Side Effects Report #5469149-9
Consumer or non-health professional from JAPAN reported GLEEVEC problem on Sept 19, 2007. Female patient, child 2 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: blood creatine phosphokinase increased, growth retardation, pain in extremity. GLEEVEC dosage: 170 MG/D. Patient recovered.

Gleevec Side Effects Report #5469686-7
GLEEVEC problem was reported by a Physician from FRANCE on Sept 24, 2007. Male patient, 67 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: macular oedema, maculopathy, retinal disorder, retinal haemorrhage, retinal operation, visual disturbance. GLEEVEC dosage: unknown. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5470549-1
Consumer or non-health professional from FRANCE reported GLEEVEC problem on Sept 26, 2007. Female patient, 49 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: cushing's syndrome, muscle spasms. GLEEVEC dosage: 400 MG, QD. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5470574-0
GLEEVEC problem was reported by a Physician from UNITED STATES on Sept 21, 2007. Female patient, 56 years of age, was diagnosed with chronic myeloid leukaemia, neuropathy, adrenal insufficiency, hypothyroidism, cardiac failure congestive and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: blood creatinine increased, blood glucose increased, blood urea increased, renal atrophy, renal failure, ultrasound abdomen abnormal. GLEEVEC dosage: 400 MG, QD. During the same period patient was treated with NEURONTIN, HYDROCORTISONE, SYNTHROID, COREG, LASIX. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5474233-X
Physician from UNITED STATES reported GLEEVEC problem on Sept 28, 2007. Female patient, 45 years of age, was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: acne, fluid retention, hepatic encephalopathy, hepatic failure, hepatotoxicity, liver injury, oedema peripheral, portal hypertension, splenomegaly. GLEEVEC dosage: unknown. Patient recovered.

Gleevec Side Effects Report #5403585-1
GLEEVEC problem was reported by a Physician from UNITED KINGDOM on July 24, 2007. Female patient, 34 years of age, weighting 143.3 lb, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: body temperature increased, fatigue, haematocrit decreased, hyperaesthesia, hypoaesthesia, lymphocyte count decreased, mean cell volume abnormal, paraesthesia, red blood cell count decreased. GLEEVEC dosage: 400MG / DAY. During the same period patient was treated with LENOGRASTIM, ASPIRIN. Patient recovered.

Gleevec Side Effects Report #5403602-9
Pharmacist from BRAZIL reported GLEEVEC problem on July 20, 2007. Male patient was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: hepatic enzyme increased, hepatic steatosis, hepatitis. GLEEVEC dosage: 400 MG, QD. Patient recovered.

Gleevec Side Effects Report #5403620-0
GLEEVEC problem was reported by a Physician from UNITED STATES on July 23, 2007. Female patient, 43 years of age, weighting 259.9 lb, was diagnosed with chronic myeloid leukaemia, gastrooesophageal reflux disease, anxiety, diabetes mellitus, neuropathy and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: anxiety. GLEEVEC dosage: 700 MG, QD. During the same period patient was treated with PREVACID, EFFEXOR, GLUCOPHAGE, NEURONTIN. Patient recovered.

Gleevec Side Effects Report #5403652-2
Consumer or non-health professional from UNITED STATES reported GLEEVEC problem on July 29, 2007. Female patient, 80 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: asthenia, back pain, blast crisis in myelogenous leukaemia, cardiac failure, cerebrovascular accident, colonoscopy abnormal, diabetes mellitus, dyspnoea. GLEEVEC dosage: unknown. During the same period patient was treated with INSULIN. Patient was hospitalized. Patient died on 07/18/2007.

Gleevec Side Effects Report #5404790-0
GLEEVEC problem was reported by a Physician from UNITED STATES on July 25, 2007. Female patient, 80 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: amaurosis fugax, carotid artery stenosis, migraine, ultrasound doppler, visual field defect. GLEEVEC dosage: 400 MG, QD. Patient recovered.

Gleevec Side Effects Report #5404792-4
Health Professional from UNITED STATES reported GLEEVEC problem on July 27, 2007. Female patient, 32 years of age, weighting 220.5 lb, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: caesarean section, cephalo-pelvic disproportion, normal newborn. GLEEVEC dosage: 300 MG, QD. During the same period patient was treated with PRENATAL VITAMINS. Patient recovered.

Gleevec Side Effects Report #5404815-2
GLEEVEC problem was reported by a Physician from UNITED STATES on July 30, 2007. Female patient, 63 years of age, was diagnosed with chronic myeloid leukaemia, hypertension, gastritis, coronary artery disease and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: granulocytopenia, oedema, thrombocythaemia, white blood cell count decreased. GLEEVEC dosage: 400 MG, QD. During the same period patient was treated with ZESTRIL, PROPRANOLOL, PREVACID, ECOTRIN. Patient recovered.

Gleevec Side Effects Report #5404850-4
Physician from UNITED STATES reported GLEEVEC problem on July 27, 2007. Male patient, 56 years of age, weighting 184.0 lb, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: aldolase increased, blood creatine phosphokinase increased, myalgia, myositis. GLEEVEC dosage: 400 MG, QD. Patient recovered.

Gleevec Side Effects Report #5404853-X
GLEEVEC problem was reported by a Consumer or non-health professional from UNITED STATES on July 26, 2007. Female patient, 81 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: angiogram abnormal, cardiac disorder, erythema, hyponatraemia, hypotension, oedema peripheral, pain in extremity, peripheral vascular disorder, pleural disorder. GLEEVEC dosage: unknown. During the same period patient was treated with CODEINE SUL, MOTRIN, SANDOSTATIN, METOLAZONE, HALDOL, ZAROXOLYN, VITAMIN CAP, NEXIUM. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5405601-X
Physician from AUSTRALIA reported GLEEVEC problem on July 27, 2007. Male patient, 74 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: confusional state, depressed level of consciousness, electroencephalogram abnormal, encephalitis herpes. GLEEVEC dosage: unknown. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5405609-4
GLEEVEC problem was reported by a Physician from UNITED KINGDOM on July 31, 2007. Female patient, 56 years of age, weighting 154.3 lb, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: coombs direct test negative, haemoglobin decreased, haemolysis, haemolytic anaemia, haptoglobin decreased. GLEEVEC dosage: 400MG/DAY. Patient recovered.

Gleevec Side Effects Report #5405629-X
Physician from JAPAN reported GLEEVEC problem on July 30, 2007. Male patient, 68 years of age, was diagnosed with gastrointestinal stromal tumour and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: colitis ulcerative, melaena. GLEEVEC dosage: unknown. Patient recovered.

Gleevec Side Effects Report #5405637-9
GLEEVEC problem was reported by a Consumer or non-health professional from JAPAN on July 30, 2007. Male patient, 63 years of age, weighting 119.0 lb, was diagnosed with gastrointestinal stromal tumour and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: cardiac failure congestive, cardiomegaly, dyspnoea, fluid retention, fusobacterium infection, inflammation, lung abscess, pleural effusion, purulent discharge. GLEEVEC dosage: 400 MG/D. During the same period patient was treated with LANSOPRAZOLE, FERROMIA, NAUZELIN, PELTAZON, PREDNISOLONE, CEFAMEZIN. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5405648-3
Health Professional from JAPAN reported GLEEVEC problem on July 30, 2007. Male patient, 54 years of age, weighting 149.9 lb, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: blood bilirubin increased, coma hepatic, depressed level of consciousness, dyspepsia, fatigue, haemoglobin decreased, hepatic encephalopathy, hepatitis, hepatitis b. GLEEVEC dosage: 300 MG/DAY. During the same period patient was treated with ADALAT, ALLOPURINOL. Patient was hospitalized. Patient died on 06/21/2004.

Gleevec Side Effects Report #5406736-8
GLEEVEC problem was reported by a Consumer or non-health professional from SWEDEN on July 31, 2007. Male patient, 60 years of age, was diagnosed with gastrointestinal stromal tumour and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: squamous cell carcinoma of skin. GLEEVEC dosage: unknown. Patient recovered.

Gleevec Side Effects Report #5406768-X
Physician from UNITED STATES reported GLEEVEC problem on Aug 01, 2007. Male patient, 29 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: diplopia, eyelid ptosis, iiird nerve paralysis, intubation, mastication disorder, muscular weakness, myasthenia gravis, trigeminal palsy, viith nerve paralysis. GLEEVEC dosage: 400 MG, QD. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5408062-X
GLEEVEC problem was reported by a Physician from SPAIN on Aug 01, 2007. Male patient, 75 years of age, was diagnosed with gastrointestinal stromal tumour and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: pneumonia aspiration, pulmonary fibrosis. GLEEVEC dosage: 400 MG/DAY. Patient recovered.

Gleevec Side Effects Report #5408077-1
Consumer or non-health professional from UNITED STATES reported GLEEVEC problem on Aug 02, 2007. Female patient, 35 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: cholecystectomy, dysuria, furuncle, headache, meningitis aseptic, pyrexia, transfusion reaction. GLEEVEC dosage: 400 MG, QD. During the same period patient was treated with GAMMAR I, GAMMAR I, GAMMAR I, GAMMAR I, GAMMAR I. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5409242-X
GLEEVEC problem was reported by a Health Professional from UNITED STATES on Aug 02, 2007. Female patient, 26 years of age, weighting 134.3 lb, was diagnosed with chronic myeloid leukaemia, contraception and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: abortion induced. GLEEVEC dosage: 600 MG, QD. During the same period patient was treated with CONTRACEPTIVES TOPICAL USE. Patient recovered.

Gleevec Side Effects Report #5409247-9
Consumer or non-health professional from TAIWAN, PROVINCE OF CHINA reported GLEEVEC problem on Aug 07, 2007. Female patient, 79 years of age, was diagnosed with gastrointestinal stromal tumour and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: ascites, infection. GLEEVEC dosage: 300 MG/D. Patient was hospitalized. Patient died on 07/27/2007.

Gleevec Side Effects Report #5411723-X
GLEEVEC problem was reported by a Physician from GERMANY on Aug 08, 2007. Male patient was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: arteriogram coronary abnormal, coronary artery disease. GLEEVEC dosage: 400 MG, QD. Patient recovered.

Gleevec Side Effects Report #5411724-1
Health Professional from UNITED STATES reported GLEEVEC problem on Aug 08, 2007. Male patient, 81 years of age, weighting 225.0 lb, was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: respiratory failure. GLEEVEC dosage: unknown. Patient died on 08/05/2007.

Gleevec Side Effects Report #5411744-7
GLEEVEC problem was reported by a Physician from UNITED KINGDOM on Aug 03, 2007. Female patient, 69 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: pulmonary hypertension, ventricular dysfunction. GLEEVEC dosage: 300/400 MG PER DAY ALTERNATLY. During the same period patient was treated with FRUSEMIDE, BISOPROLOL, ALLOPURINOL, GLICLAZIDE, LIPITOR, ACETYLSALICYLIC ACID SRT, RAMIPRIL, LANTUS. Patient recovered.

Gleevec Side Effects Report #5411749-6
Physician from JAPAN reported GLEEVEC problem on Aug 08, 2007. Female patient, 76 years of age, was diagnosed with gastrointestinal stromal tumour, gastritis prophylaxis and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: anorexia, blood beta-d-glucan increased, cough, dyspnoea, interstitial lung disease, malaise, oxygen saturation decreased. GLEEVEC dosage: 400 MG/D. During the same period patient was treated with FAMOTIDINE. Patient was hospitalized. Patient died on 06/02/2007.

Gleevec Side Effects Report #5411753-8
GLEEVEC problem was reported by a Physician from JAPAN on Aug 08, 2007. Male patient, 77 years of age, weighting 183.0 lb, was diagnosed with gastrointestinal stromal tumour and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: neoplasm malignant, therapeutic embolisation. GLEEVEC dosage: 400 MG/D. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5411758-7
Physician from UNITED STATES reported GLEEVEC problem on Aug 06, 2007. Male patient, 29 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: diplopia, eyelid ptosis, iiird nerve paralysis, intubation, leukocytosis, mastication disorder, muscular weakness, myasthenia gravis, tensilon test abnormal. GLEEVEC dosage: 400 MG, QD. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5411772-1
GLEEVEC problem was reported by a Physician from JAPAN on Aug 06, 2007. Male patient, 56 years of age, weighting 205.0 lb, was diagnosed with gastrointestinal stromal tumour and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: anaemia, melaena, neoplasm progression, tumour haemorrhage. GLEEVEC dosage: 400 MG, QD. Patient died on 08/17/2006.

Gleevec Side Effects Report #5412422-0
Consumer or non-health professional from JAPAN reported GLEEVEC problem on Aug 09, 2007. Male patient, 61 years of age, was diagnosed with gastrointestinal stromal tumour and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: blood lactate dehydrogenase increased, cough, diarrhoea, dyspnoea, eyelid oedema, hypersensitivity, interstitial lung disease, lung neoplasm malignant, metastases to central nervous system. GLEEVEC dosage: 100 MG/D. During the same period patient was treated with BERIZYM, LAC B, URSO, ZYLORIC. Patient was hospitalized and became disabled. Patient died on 05/04/2004.

Gleevec Side Effects Report #5415573-X
GLEEVEC problem was reported by a Physician from UNITED STATES on Aug 08, 2007. Female patient, 25 years of age, weighting 153.2 lb, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: premature labour. GLEEVEC dosage: 400 MG, QD. Patient recovered.

Gleevec Side Effects Report #5415574-1
Physician from UNITED STATES reported GLEEVEC problem on Aug 08, 2007. Female patient, 25 years of age, weighting 153.2 lb, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: premature labour. GLEEVEC dosage: 400 MG, QD. Patient recovered.

Gleevec Side Effects Report #5416337-3
GLEEVEC problem was reported by a Physician from UNITED STATES on Aug 09, 2007. Female patient, child 8 years of age, was diagnosed with diffuse large b-cell lymphoma stage iii and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: eye pain, papilloedema, retinal vein thrombosis. GLEEVEC dosage: 300 MG, QD. During the same period patient was treated with ASPARAGINASE. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5416340-3
Physician from UNITED STATES reported GLEEVEC problem on Aug 09, 2007. Male patient, 71 years of age, was diagnosed with gastrointestinal stromal tumour and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: blood urea increased, creatinine renal clearance decreased, tumour lysis syndrome. GLEEVEC dosage: 400 MG, QD. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5416394-4
GLEEVEC problem was reported by a Health Professional from UNITED STATES on Aug 13, 2007. Male patient, 81 years of age, weighting 225.0 lb, was diagnosed with myeloproliferative disorder and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: respiratory failure. GLEEVEC dosage: unknown. During the same period patient was treated with OCUVITE, HYDREA, CADUET, RYTHMOL, CEFADROXIL, CENTRUM SILVER. Patient was hospitalized. Patient died on 08/05/2007.

Gleevec Side Effects Report #5417824-4
Physician from UNITED STATES reported GLEEVEC problem on Aug 14, 2007. Female patient, 25 years of age, weighting 153.2 lb, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: premature labour. GLEEVEC dosage: 400 MG, QD. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5419062-8
GLEEVEC problem was reported by a Physician from FRANCE on Aug 09, 2007. Female patient, 60 years of age, weighting 220.5 lb, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: blood creatinine increased, blood potassium increased, hypokalaemia, renal failure. GLEEVEC dosage: 400 MG DAILY. Patient recovered.

Gleevec Side Effects Report #5419073-2
Physician from JAPAN reported GLEEVEC problem on Aug 10, 2007. Female patient, child 11 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: deafness. GLEEVEC dosage: 400MG, 600MG. Patient recovered.

Gleevec Side Effects Report #5419126-9
GLEEVEC problem was reported by a Physician from JAPAN on Aug 09, 2007. Female patient, 56 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: blood sodium decreased, inappropriate antidiuretic hormone secretion, oedema, weight increased. GLEEVEC dosage: 600 MG/D. During the same period patient was treated with VINCRISTINE, CYCLOPHOSPHAMIDE, DAUNORUBICIN. Patient recovered.

Gleevec Side Effects Report #5420454-1
Physician from UNITED STATES reported GLEEVEC problem on Aug 09, 2007. Female patient was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: abasia, deep vein thrombosis, hepatic cirrhosis, liver function test abnormal, oedema peripheral. GLEEVEC dosage: 800 MG, QD. Patient recovered.

Gleevec Side Effects Report #5420458-9
GLEEVEC problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 10, 2007. Male patient, 36 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: blood creatine phosphokinase increased. GLEEVEC dosage: 400 MG, QD. Patient recovered.

Gleevec Side Effects Report #5420462-0
Health Professional from GREECE reported GLEEVEC problem on Aug 10, 2007. Male patient, 73 years of age, was diagnosed with gastrointestinal stromal tumour, primary hypothyroidism and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: blood creatinine increased, blood thyroid stimulating hormone decreased, haematocrit decreased, primary hypothyroidism, pruritus, thyroxine increased. GLEEVEC dosage: 400 MG/DAY. During the same period patient was treated with LEVOTHYROXINE. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5420482-6
GLEEVEC problem was reported by a Physician from UNITED STATES on Aug 16, 2007. Female patient, 76 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: acute coronary syndrome, dialysis, gastrointestinal haemorrhage, pneumonia, renal failure chronic. GLEEVEC dosage: 300 MG, QD. Patient recovered.

Gleevec Side Effects Report #5421972-2
Physician from ISRAEL reported GLEEVEC problem on Aug 12, 2007. Male patient, 55 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: diarrhoea, gastrointestinal mucosal disorder, haemorrhoids. GLEEVEC dosage: 400 MG/D. Patient recovered.

Gleevec Side Effects Report #5421991-6
GLEEVEC problem was reported by a Physician from BRAZIL on Aug 14, 2007. Male patient, 57 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: aplasia, blood albumin decreased, bronchopneumonia, haematocrit decreased, hepatosplenomegaly, platelet count decreased, pleural effusion, pyrexia, white blood cell count decreased. GLEEVEC dosage: 400 MG/D. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5421994-1
Consumer or non-health professional from UNITED STATES reported GLEEVEC problem on Aug 13, 2007. Female patient, 35 years of age, was diagnosed with chronic myeloid leukaemia, hypogammaglobulinaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: cholecystectomy, depression, dysuria, headache, malaise, meningitis aseptic, migraine, pyrexia, rash pustular. GLEEVEC dosage: 400 MG, QD. During the same period patient was treated with GAMMAR I, GAMMAR I, GAMMAR I, GAMMAR I, GAMMAR I. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5423310-8
GLEEVEC problem was reported by a Physician from UNITED STATES on Aug 14, 2007. Male patient was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: colon cancer, therapeutic response decreased. GLEEVEC dosage: 400 MG, QD. Patient recovered.

Gleevec Side Effects Report #5423321-2
Physician from reported GLEEVEC problem on Aug 12, 2007. Male patient, 55 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: anal abscess, anal fissure, colostomy, gastrointestinal necrosis, neutropenia, proctalgia. GLEEVEC dosage: unknown. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5423323-6
GLEEVEC problem was reported by a Physician from UNITED KINGDOM on Aug 13, 2007. Male patient was diagnosed with hypereosinophilic syndrome and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: dizziness, hypoglycaemia. GLEEVEC dosage: 100MG/DAY. Patient recovered.

Gleevec Side Effects Report #5423324-8
Physician from AUSTRIA reported GLEEVEC problem on Aug 14, 2007. Female patient, child 6 years of age, weighting 41.89 lb, was diagnosed with astrocytoma and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: myotonia, tonic clonic movements. GLEEVEC dosage: 200 MG/D. Patient recovered.

Gleevec Side Effects Report #5424667-4
GLEEVEC problem was reported by a Consumer or non-health professional from AUSTRALIA on Aug 15, 2007. Female patient, 60 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: chorioretinopathy. GLEEVEC dosage: unknown. Patient recovered.

Gleevec Side Effects Report #5425153-8
Physician from GERMANY reported GLEEVEC problem on Aug 17, 2007. Female patient, 30 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: caesarean section. GLEEVEC dosage: unknown. Patient recovered.

Gleevec Side Effects Report #5425832-2
GLEEVEC problem was reported by a Physician from GERMANY on Aug 17, 2007. Female patient, weighting 7.94 lb, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: premature baby, respiratory disorder. GLEEVEC dosage: unknown. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5426293-X
Physician from UNITED STATES reported GLEEVEC problem on Aug 17, 2007. Male patient, 29 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: diplopia, eyelid ptosis, iiird nerve paralysis, intubation, leukocytosis, mastication disorder, muscular weakness, myasthenia gravis, tensilon test abnormal. GLEEVEC dosage: 400 MG, QD. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5427069-X
GLEEVEC problem was reported by a Physician from UNITED STATES on Aug 15, 2007. Male patient, 71 years of age, weighting 186.0 lb, was diagnosed with gastrointestinal stromal tumour, hypothyroidism, sleep disorder and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: acute prerenal failure, ascites, blood creatinine increased, blood phosphorus increased, blood urea increased, blood uric acid increased, creatinine renal clearance decreased, hyperkalaemia, hyponatraemia. GLEEVEC dosage: 400 MG, QD. During the same period patient was treated with LEVOTHYROXINE, AMBIEN. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5427072-X
Physician from GERMANY reported GLEEVEC problem on Aug 17, 2007. Female patient, weighting 7.94 lb, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: premature baby, respiratory disorder. GLEEVEC dosage: unknown. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5427081-0
GLEEVEC problem was reported by a Physician from GERMANY on Aug 17, 2007. Female patient, 30 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: caesarean section. GLEEVEC dosage: unknown. Patient recovered.

Gleevec Side Effects Report #5427185-2
Physician from AUSTRALIA reported GLEEVEC problem on Aug 16, 2007. Male patient, 58 years of age, was diagnosed with chordoma and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: blood creatinine abnormal, dehydration, escherichia urinary tract infection, nausea, oral intake reduced, renal impairment, vomiting. GLEEVEC dosage: 600 MG, QD. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5430325-2
GLEEVEC problem was reported by a Physician from FRANCE on Aug 24, 2007. Female patient, 52 years of age, was diagnosed with chronic myeloid leukaemia, autoimmune hepatitis and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: autoimmune hepatitis. GLEEVEC dosage: 600 MG PER DAY. During the same period patient was treated with AZATHIOPRINE. Patient recovered.

Gleevec Side Effects Report #5430327-6
Physician from UNITED STATES reported GLEEVEC problem on Aug 24, 2007. Male patient, 63 years of age, weighting 149.7 lb, was diagnosed with thyroid cancer and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: dyspnoea, malignant neoplasm progression, metastatic neoplasm, optic neuropathy, rectal haemorrhage, vision blurred. GLEEVEC dosage: 400 MG, BID. During the same period patient was treated with VICODIN, ADVIL LIQUI, ATIVAN, ACCUPRIL, PRILOSEC, BISOPROLOL. Patient was hospitalized. Patient died on 07/16/2007.

Gleevec Side Effects Report #5430332-X
GLEEVEC problem was reported by a Physician from UNITED STATES on Aug 24, 2007. Male patient, 23 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: idiopathic thrombocytopenic purpura, platelet count decreased. GLEEVEC dosage: unknown. Patient recovered.

Gleevec Side Effects Report #5430335-5
Consumer or non-health professional from UNITED STATES reported GLEEVEC problem on Aug 20, 2007. Female patient, 35 years of age, was diagnosed with chronic myeloid leukaemia, hypogammaglobulinaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: cholecystectomy, depression, dysuria, headache, malaise, meningitis aseptic, migraine, pyrexia, rash pustular. GLEEVEC dosage: 400 MG, QD. During the same period patient was treated with GAMMAR I, GAMMAR I, GAMMAR I, GAMMAR I, GAMMAR I. Patient was hospitalized. Patient recover