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Hydrochlorothiazid Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 2161 

Type 2 Diabetes Mellitus, Hypertension, Tendon Disorder, Tendon Rupture, Laboratory Test Abnormal, Myalgia, Lipids Increased, Muscle Spasms, Thyroid Cancer (8462457-9)
on Jun 15, 2012 Female from UNITED STATES , 61 years of age, weighting 169.1 lb, was diagnosed with
  • hypertension
and was treated with Hydrochlorothiazide. Directly after, patient experienced the unwanted or unexpected Hydrochlorothiazid side effects: type 2 diabetes mellitus, hypertension, tendon disorder, tendon rupture, laboratory test abnormal, myalgia, lipids increased, muscle spasms, thyroid cancer. Hydrochlorothiazide dosage: 25.
Associated medications used:
  • Lisinopril
  • Crestor
  • Crestor
  • Crestor
  • Actos
  • Metformin Hcl
  • Glipizide
  • Levoxyl
Patient was hospitalized.

Body Height Decreased, Osteoporosis (8462432-4)
Patient was taking Hydrochlorothiazide. Patient felt the following Hydrochlorothiazid side effects: body height decreased, osteoporosis on Jun 19, 2012 from UNITED STATES Additional patient health information: Female , weighting 135.0 lb, was diagnosed with
  • hypertension
and. Hydrochlorothiazide dosage: Unk.
Multiple prescriptions taken:
  • Lisinopril (Unk)
  • Premarin (1.25 Mg, 1x/day)
  • Premarin (2.5 Mg, Unk)


Hyponatraemia (8461858-2)
Adverse event was reported on Jun 19, 2012 by a Female taking Hydrochlorothiazide (Dosage: N/A) was diagnosed with
  • hypertension
and. Location: UNITED STATES , 86 years of age, weighting 108.0 lb, After Hydrochlorothiazid was administered, patient encountered several Hydrochlorothiazid side effects: hyponatraemia.

Immune System Disorder (8459233-X)
on Jun 18, 2012 Female from UNITED STATES , weighting 140.0 lb, was treated with Hydrochlorothiazide. Directly after, patient experienced the unwanted or unexpected Hydrochlorothiazid side effects: immune system disorder. Hydrochlorothiazide dosage: 50 Mg, Daily.
Associated medications used:
  • Iron (Unk, Daily)
  • Hydrocodone (^7.5/5^, 2x/day)
  • Baclofen (20 Mg, 3x/day)
  • Sulfasalazine (1000 Mg, 2x/day)
  • Omeprazole (20 Mg, Daily)
  • Magnesium (Unk, Daily)
  • Coumadin (Unk, Daily)
  • Vitamin B-12 (Unk, Daily)



Eye Pruritus, Rash, Swelling Face (8459175-X)
on Jun 12, 2012 Female from UNITED STATES , 88 years of age, weighting 144.4 lb, was diagnosed with
  • hypertension
and was treated with Hydrochlorothiazide. Patient felt the following Hydrochlorothiazid side effects: eye pruritus, rash, swelling face. Hydrochlorothiazide dosage: 25 Mg, Qd.
Multiple prescriptions taken:
  • Norvasc (5 Mg, Qd)
  • Benadryl (Unk)
  • Lisinopril (200 Mg, Bid)
  • Prolia (Unk Unk, Q6mo)
  • Clonidine (0.3 Mg, Tid)
  • Simvastatin (20 Mg, Qd)


Intervertebral Disc Protrusion (8458828-7)
Patient was taking Hydrochlorothiazide. After Hydrochlorothiazid was administered, patient encountered several Hydrochlorothiazid side effects: intervertebral disc protrusion on Jun 15, 2012 from BRAZIL Additional patient health information: Female , 66 years of age, weighting 154.3 lb, was diagnosed with
  • renal disorder
  • diabetes mellitus
  • blood pressure increased
and. Hydrochlorothiazide dosage: Unk.
Multiple concurrent drugs taken:
  • Insulin (Unk)
  • Amlodipine (Unk)
  • Enalapril (Unk)
  • Cebralat (Unk)
  • Metformin (Unk)
  • Paracetamol (Unk)
  • Lyrica (75 Mg (one Capsule), 2x/day)
  • Somalgin (Unk)


Blood Pressure Increased, Blood Catecholamines Decreased, Syncope, Blood Corticotrophin Abnormal, Restlessness, Decreased Appetite, Migraine, Temporomandibular Joint Syndrome, Condition Aggravated (8458819-6)
Adverse event was reported on May 31, 2012 by a Male taking Hydrochlorothiazide (Dosage: N/A) was diagnosed with
  • blood pressure increased
and. Location: UNITED STATES , 40 years of age, weighting 153.0 lb, Directly after, patient experienced the unwanted or unexpected Hydrochlorothiazid side effects: blood pressure increased, blood catecholamines decreased, syncope, blood corticotrophin abnormal, restlessness, decreased appetite, migraine, temporomandibular joint syndrome, condition aggravated.
Associated medications used:
  • Oxycodone Hcl
  • Cymbalta (30 Mg Daily, 60 Mg Daily, 80 Mg Daily, 120 Mg Daily, 6-8 Years Ago)
  • Cymbalta (30 Mg Daily, 60 Mg Daily, 80 Mg Daily, 120 Mg Daily, 6-8 Years Ago)
  • Cymbalta (30 Mg Daily, 60 Mg Daily, 80 Mg Daily, 120 Mg Daily, 6-8 Years Ago)
  • Cymbalta (30 Mg Daily, 60 Mg Daily, 80 Mg Daily, 120 Mg Daily, 6-8 Years Ago)
  • Cymbalta (30 Mg Daily, 60 Mg Daily, 80 Mg Daily, 120 Mg Daily, 6-8 Years Ago)
  • Cymbalta (30 Mg Daily, 60 Mg Daily, 80 Mg Daily, 120 Mg Daily, 6-8 Years Ago)
  • Lipitor


Confusional State, Dysarthria, Disturbance In Attention (8458326-0)
on Jun 05, 2012 Female from GERMANY , 91 years of age, was treated with Hydrochlorothiazide. Patient felt the following Hydrochlorothiazid side effects: confusional state, dysarthria, disturbance in attention. Hydrochlorothiazide dosage: N/A.
Multiple prescriptions taken:
  • Uro-vaxom (escherichia Coli Lysate Siccum)
  • Ramipril
  • Vigantoletten 1000 (colcalciferol)
  • Alendronic Acid (alendronic Acid)
  • Keimax (ceftibuten /01166201/) (Po)
Patient was hospitalized.

Compression Fracture, Epistaxis, Cardiac Failure Congestive, Pneumonia (8456737-0)
on Sep 01, 2011 Male from UNITED STATES , 80 years of age, was treated with Hydrochlorothiazide. After Hydrochlorothiazid was administered, patient encountered several Hydrochlorothiazid side effects: compression fracture, epistaxis, cardiac failure congestive, pneumonia. Hydrochlorothiazide dosage: N/A.
Multiple concurrent drugs taken:
  • Unisom
  • Fish Oil (fish Oil)
  • Lenalidomide (25 Mg, Daily X 21 Days, Po)
  • Simvastatin
Patient was hospitalized.

Intraocular Pressure Increased, Visual Impairment (8455534-X)
Patient was taking Hydrochlorothiazide. Directly after, patient experienced the unwanted or unexpected Hydrochlorothiazid side effects: intraocular pressure increased, visual impairment on Jun 13, 2012 from BRAZIL Additional patient health information: Male , 64 years of age, was diagnosed with
  • hypertension
and. Hydrochlorothiazide dosage: Unk.
Associated medications used:
  • Xalatan (One Drop In Each Eye (3 Ug) 1x/day)
  • Amlodipine (Unk)
  • Captopril (180 Tablets Monthly)


Pain, Cyst, Bradycardia, Pulmonary Embolism, Cerebrovascular Disorder, Cardiac Failure Congestive, Dementia, Left Ventricular Hypertrophy, Cardiomegaly (8455517-X)
Adverse event was reported on Jun 12, 2012 by a Female taking Hydrochlorothiazide (Dosage: N/A) . Location: UNITED STATES , 80 years of age, weighting 157.0 lb, Patient felt the following Hydrochlorothiazid side effects: pain, cyst, bradycardia, pulmonary embolism, cerebrovascular disorder, cardiac failure congestive, dementia, left ventricular hypertrophy, cardiomegaly.
Multiple prescriptions taken:
  • Nolvadex
  • Aspirin (Enteric Coated)
  • Quinine Sulfate
  • Pred Forte
  • Oxycodone And Acetaminophen
  • Zestril
  • Paxil
  • Prochlorperazine
Patient was hospitalized and became disabled.

Dysphagia, Eating Disorder, Deep Vein Thrombosis, Haematocrit Decreased, Salivary Hypersecretion, Haemoglobin Decreased (8455009-8)
on Jun 14, 2012 Female from UNITED STATES , 84 years of age, weighting 207.2 lb, was treated with Hydrochlorothiazide. After Hydrochlorothiazid was administered, patient encountered several Hydrochlorothiazid side effects: dysphagia, eating disorder, deep vein thrombosis, haematocrit decreased, salivary hypersecretion, haemoglobin decreased. Hydrochlorothiazide dosage: N/A.
Multiple concurrent drugs taken:
  • Calcium + Vitamin D
  • Omeprazole
  • Botox (Once Im)
  • Avapro
  • Vitamin B-12
Patient was hospitalized.

Blood Pressure Systolic Increased, Decreased Appetite, Insomnia, Liver Disorder, Agoraphobia, Aphagia, Suicidal Ideation, Condition Aggravated, Self Injurious Behaviour (8454717-2)
on May 30, 2012 Female from UNITED STATES , 60 years of age, weighting 125.0 lb, was treated with Hydrochlorothiazide. Directly after, patient experienced the unwanted or unexpected Hydrochlorothiazid side effects: blood pressure systolic increased, decreased appetite, insomnia, liver disorder, agoraphobia, aphagia, suicidal ideation, condition aggravated, self injurious behaviour. Hydrochlorothiazide dosage: N/A.
Associated medications used:
  • Cyclosporine
  • Aspirin
  • Xyrem (6 Gm (3 Gm, 2 In 1 D), Oral; 9 Gm (4.5 Gm, 2 In 1 D), Oral; 9 Gm (4.5, Gm, 2 In 1 D), Oral)
  • Xyrem (6 Gm (3 Gm, 2 In 1 D), Oral; 9 Gm (4.5 Gm, 2 In 1 D), Oral; 9 Gm (4.5, Gm, 2 In 1 D), Oral)
  • Xyrem (6 Gm (3 Gm, 2 In 1 D), Oral; 9 Gm (4.5 Gm, 2 In 1 D), Oral; 9 Gm (4.5, Gm, 2 In 1 D), Oral)
  • Xyrem (6 Gm (3 Gm, 2 In 1 D), Oral; 9 Gm (4.5 Gm, 2 In 1 D), Oral; 9 Gm (4.5, Gm, 2 In 1 D), Oral)
  • Xyrem (6 Gm (3 Gm, 2 In 1 D), Oral; 9 Gm (4.5 Gm, 2 In 1 D), Oral; 9 Gm (4.5, Gm, 2 In 1 D), Oral)
  • Xyrem (6 Gm (3 Gm, 2 In 1 D), Oral; 9 Gm (4.5 Gm, 2 In 1 D), Oral; 9 Gm (4.5, Gm, 2 In 1 D), Oral)
Patient was hospitalized and became disabled.

Breast Cancer Female, Dizziness, Blood Potassium Decreased, Hypotension, Electrocardiogram St-t Change, Cardiac Enzymes Increased, Dehydration (8450701-3)
Patient was taking Hydrochlorothiazide. Patient felt the following Hydrochlorothiazid side effects: breast cancer female, dizziness, blood potassium decreased, hypotension, electrocardiogram st-t change, cardiac enzymes increased, dehydration on Jun 01, 2012 from UNITED STATES Additional patient health information: Female , 56 years of age, weighting 188.9 lb, was diagnosed with
  • hypertension
and. Hydrochlorothiazide dosage: (125 Mg, 1 D), Oral.
Multiple prescriptions taken:
  • Zantac
  • Lisinopril ((20 Mg, 1 D), Oral)
  • Neratinib ((240 Mg, 1 D), Oral)
  • Doxorubicin Hydrochloride (60 Mg/m2, Day 1 Of C# 5-8, Intravenous)
  • Cyclophosphamide (600 Mg/m2, Day 1 Of C 5-8, Intravenous)
  • Paclitaxel (80 Mg/m2, Cyclic, Day 1, 8, 15 Of C#1-4; Intravenous)
  • Amlodipine ((10 Mg, 1 D), Oral)
Patient was hospitalized.

Arthropathy, Depression, Yellow Skin, Ocular Icterus, Headache, Blood Pressure Increased, Musculoskeletal Stiffness, Joint Stiffness (8449844-X)
Adverse event was reported on Jun 06, 2012 by a Female taking Hydrochlorothiazide (Dosage: N/A) . Location: UNITED STATES , 48 years of age, After Hydrochlorothiazid was administered, patient encountered several Hydrochlorothiazid side effects: arthropathy, depression, yellow skin, ocular icterus, headache, blood pressure increased, musculoskeletal stiffness, joint stiffness.
Multiple concurrent drugs taken:
  • Cymbalta (60 Mg, Qod)
  • Cymbalta (60 Mg, Qd)


Coeliac Disease, Migraine, Abdominal Pain, Vomiting, Adrenal Insufficiency, Retinal Detachment, Disability, Cataract Operation, Fibromyalgia (8447872-1)
on May 24, 2012 Female from UNITED STATES , 43 years of age, weighting 240.0 lb, was treated with Hydrochlorothiazide. Directly after, patient experienced the unwanted or unexpected Hydrochlorothiazid side effects: coeliac disease, migraine, abdominal pain, vomiting, adrenal insufficiency, retinal detachment, disability, cataract operation, fibromyalgia. Hydrochlorothiazide dosage: N/A.
Associated medications used:
  • Xalatan
  • Acetaminophen
  • Geodon
  • Betoptic S Eye Drops
  • Dicyclomine Hcl (;tid;po)
  • Klor-con
  • Omeprazole
  • Phenergan


Malaise, Abdominal Pain Upper, Diarrhoea, Gastrointestinal Disorder, Dehydration, Nausea, Frequent Bowel Movements, Asthenia, Decreased Appetite (8446942-1)
on Jun 13, 2012 Female from UNITED STATES , weighting 260.0 lb, was diagnosed with
  • blood pressure decreased
and was treated with Hydrochlorothiazide. Patient felt the following Hydrochlorothiazid side effects: malaise, abdominal pain upper, diarrhoea, gastrointestinal disorder, dehydration, nausea, frequent bowel movements, asthenia, decreased appetite. Hydrochlorothiazide dosage: 25mg Daily Po.

Pancytopenia, Pneumonia (8445685-8)
Patient was taking Hydrochlorothiazide. After Hydrochlorothiazid was administered, patient encountered several Hydrochlorothiazid side effects: pancytopenia, pneumonia on Jun 22, 2011 from UNITED STATES Additional patient health information: Male , 66 years of age, . Hydrochlorothiazide dosage: N/A.
Multiple concurrent drugs taken:
  • Zolpidem
  • Decadron
  • Aspirin
  • Vicodin
  • Morphine
  • Percocet
  • Lenalidomide (10 Mg, Daily For 21 Days Every 28, Po)
Patient was hospitalized.

Dizziness, Spinal Cord Infarction, Paraplegia, Hypotension, Vision Blurred (8444017-9)
Adverse event was reported on May 28, 2012 by a Male taking Hydrochlorothiazide (Dosage: N/A) was diagnosed with
  • hypertension
and. Location: UNITED STATES , 59 years of age, Directly after, patient experienced the unwanted or unexpected Hydrochlorothiazid side effects: dizziness, spinal cord infarction, paraplegia, hypotension, vision blurred.
Associated medications used:
  • Sildenafil (50 Mg)
Patient was hospitalized.

Pulmonary Embolism, Pulmonary Infarction, Pain In Extremity, Deep Vein Thrombosis, Pregnancy With Contraceptive Device, Deficiency Anaemia, Paraesthesia, Impaired Work Ability, Hypokalaemia (8443931-8)
on Jun 06, 2012 Female from UNITED STATES , 32 years of age, weighting 205.0 lb, was treated with Hydrochlorothiazide. Patient felt the following Hydrochlorothiazid side effects: pulmonary embolism, pulmonary infarction, pain in extremity, deep vein thrombosis, pregnancy with contraceptive device, deficiency anaemia, paraesthesia, impaired work ability, hypokalaemia. Hydrochlorothiazide dosage: N/A.
Multiple prescriptions taken:
  • K-tab
  • Motrin
  • Nasacort Aq
  • Nuvaring
Patient was hospitalized and became disabled.

Cardiomyopathy, Arrhythmia (8443405-4)
on Jun 04, 2012 Female from SOUTH AFRICA , 58 years of age, was diagnosed with
  • weight decreased
and was treated with Hydrochlorothiazide. After Hydrochlorothiazid was administered, patient encountered several Hydrochlorothiazid side effects: cardiomyopathy, arrhythmia. Hydrochlorothiazide dosage: Unk.
Multiple concurrent drugs taken:
  • Liothyronine Sodium (Unk)
  • Metformin Hcl (Unk)
  • Sibutramine Hydrochloride Monohydrate (Unk)
Patient was hospitalized.

Rib Fracture, Low Turnover Osteopathy, Fall, Arthralgia, Fatigue, Temporomandibular Joint Syndrome, Scoliosis, Radius Fracture, Bursitis (8443149-9)
Patient was taking Hydrochlorothiazide. Directly after, patient experienced the unwanted or unexpected Hydrochlorothiazid side effects: rib fracture, low turnover osteopathy, fall, arthralgia, fatigue, temporomandibular joint syndrome, scoliosis, radius fracture, bursitis on Jun 13, 2012 from UNITED STATES Additional patient health information: Female , 54 years of age, weighting 167.6 lb, was diagnosed with
  • essential hypertension
and. Hydrochlorothiazide dosage: N/A. Patient was hospitalized and became disabled.

Monoplegia, Formication, Blood Pressure Increased, Blood Potassium Decreased (8442927-X)
Adverse event was reported on Jun 13, 2012 by a Female taking Hydrochlorothiazide (Dosage: N/A) . Location: UNITED STATES , 51 years of age, Patient felt the following Hydrochlorothiazid side effects: monoplegia, formication, blood pressure increased, blood potassium decreased. Patient was hospitalized.

Feeding Disorder, Cardiac Operation, Weight Decreased (8441019-3)
on Jun 07, 2012 Male from UNITED STATES , weighting 8.82 lb, was treated with Hydrochlorothiazide. After Hydrochlorothiazid was administered, patient encountered several Hydrochlorothiazid side effects: feeding disorder, cardiac operation, weight decreased. Hydrochlorothiazide dosage: N/A.
Multiple concurrent drugs taken:
  • Lisinopril
  • Digoxin
  • Synagis
  • Synagis
Patient was hospitalized.

Nausea, Fatigue (8439354-8)
on Jun 12, 2012 Female from UNITED STATES , weighting 142.0 lb, was treated with Hydrochlorothiazide. Directly after, patient experienced the unwanted or unexpected Hydrochlorothiazid side effects: nausea, fatigue. Hydrochlorothiazide dosage: N/A.
Associated medications used:
  • Ranitidine
  • Ascorbic Acid
  • Tasigna (300 Mg, Bid)
  • Zocor
  • Lotrel
  • Klor-con
  • Allopurinol
  • Iron


Showing 1-25 of 2161 

Hydrochlorothiazid Health Episodes

How Can Hydrochlorothiazid Affect You?

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It is very important to keep track of all side effects and discuss them with your doctor. If you think you may have a medical emergency, call your doctor or 911 immediately.

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Hydrochlorothiazid Information

Alternative HYDROCHLOROTHIAZID Names:HYDROCHLO

Active Ingredient: HYDROCHLO

More About Hydrochlorothiazid

Side Effects reported to FDA: 2161. View Hydrochlorothiazid Adverse Reports

Hydrochlorothiazid safety alerts: No

Reported deaths: 132

Reported hospitalizations: 985

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