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High Blood Pressure (16)
Heart Palpitations (6)
Cystitis Symptoms (5)
Chest Pain (3)
Diarrhea (3)
Chest Pain Rash (2)
Flatulence (2)
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Imodium Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 553 

Intestinal Obstruction (8334498-3)
on Apr 18, 2012 Male from CHINA , weighting 121.3 lb, was diagnosed with
  • abdominal pain
  • diarrhoea
and was treated with Imodium. Directly after, patient experienced the unwanted or unexpected Imodium side effects: intestinal obstruction. Imodium dosage: 4mg One Per Day.

Inflammation (8334309-6)
Patient was taking Imodium. Patient felt the following Imodium side effects: inflammation on Apr 04, 2012 from GERMANY Additional patient health information: Female , 30 years of age, weighting 147.7 lb, . Imodium dosage: 4 To 6 Capsules Per Day.
Multiple prescriptions taken:
  • Humira
  • Levothyroxine Sodium
  • Humira


Pollakiuria, Carbohydrate Antigen 19-9 Increased, Red Cell Distribution Width Increased, Carcinoembryonic Antigen Increased, Thirst, Red Blood Cell Count Decreased, Lymphocyte Count Decreased, Blood Sodium Decreased, Aspartate Aminotransferase Increased (8334037-7)
Adverse event was reported on Apr 19, 2012 by a Male taking Imodium (Dosage: N/A) . Location: CANADA , weighting 248.0 lb, After Imodium was administered, patient encountered several Imodium side effects: pollakiuria, carbohydrate antigen 19-9 increased, red cell distribution width increased, carcinoembryonic antigen increased, thirst, red blood cell count decreased, lymphocyte count decreased, blood sodium decreased, aspartate aminotransferase increased.
Multiple concurrent drugs taken:
  • Gaviscon Acid
  • Insulin
  • Prochlorperazine
  • Dexamethasone Sodium Phosphate
  • Pantoprazole
  • Avastin


Intestinal Obstruction (8327887-4)
on Apr 18, 2012 Female from CHINA , weighting 143.3 lb, was diagnosed with
  • diarrhoea
and was treated with Imodium. Directly after, patient experienced the unwanted or unexpected Imodium side effects: intestinal obstruction. Imodium dosage: 2 Capsules 3 Times A Day. Patient was hospitalized.


Pneumonitis, Pneumonia (8319369-0)
on Apr 27, 2012 Male from UNITED STATES , 68 years of age, was treated with Imodium. Patient felt the following Imodium side effects: pneumonitis, pneumonia. Imodium dosage: 1df = 2tabs.
Multiple prescriptions taken:
  • Compazine (Prn)
  • Atenolol (Mrng,if Necessary Two Times)
  • Alfuzosin Hcl
  • Omeprazole
  • Alprazolam (At Bed Time,1-2 Tabs)
  • Ambien (1df= 5-15mg Q Hs Prn)
  • Synthroid
  • Zofran (Prn)
Patient was hospitalized.

Pollakiuria, Thirst, Hyperglycaemia (8304881-0)
Patient was taking Imodium. After Imodium was administered, patient encountered several Imodium side effects: pollakiuria, thirst, hyperglycaemia on Apr 16, 2012 from CANADA Additional patient health information: Male , weighting 264.2 lb, . Imodium dosage: N/A.
Multiple concurrent drugs taken:
  • Insulin
  • Avastin
  • Gaviscon Acid
  • Pantoprazole
  • Prochlorperazine


Myelodysplastic Syndrome (8302616-9)
Adverse event was reported on Apr 12, 2012 by a Male taking Imodium (Dosage: 2 Milligram) . Location: UNITED STATES , weighting 173.5 lb, Directly after, patient experienced the unwanted or unexpected Imodium side effects: myelodysplastic syndrome.
Associated medications used:
  • Tylenol (caplet) (650 Milligram)
  • Acetaminophen-hydrocodone
  • Zometa
  • Multi-vitamins
  • Bortezomib (1 Milligram/sq. Meter)
  • Aspirin (81 Milligram)
  • Protonix (40 Milligram)
  • Vitamin B Complex Cap (1 Tablet)
Patient was hospitalized.

Cholelithiasis (8283539-0)
on Apr 05, 2012 Female from UNITED STATES , weighting 218.3 lb, was diagnosed with
  • abdominal discomfort
  • vitamin d deficiency
  • diarrhoea
and was treated with Imodium. Patient felt the following Imodium side effects: cholelithiasis. Imodium dosage: N/A.
Multiple prescriptions taken:
  • Vitamin D Supplement
Patient was hospitalized.

Torsade De Pointes, Intentional Overdose, Syncope, Ventricular Tachycardia, Electrocardiogram Qt Prolonged (8281690-2)
on Apr 09, 2012 Female from UNITED STATES , 43 years of age, was treated with Imodium. After Imodium was administered, patient encountered several Imodium side effects: torsade de pointes, intentional overdose, syncope, ventricular tachycardia, electrocardiogram qt prolonged. Imodium dosage: 140 Tablets, Daily. Patient was hospitalized.

Cardiac Disorder, Gastrooesophageal Reflux Disease, Eructation (8278126-4)
Patient was taking Imodium. Directly after, patient experienced the unwanted or unexpected Imodium side effects: cardiac disorder, gastrooesophageal reflux disease, eructation on Sep 22, 2011 from UNITED STATES Additional patient health information: Female , 62 years of age, . Imodium dosage: N/A.
Associated medications used:
  • Nexium


Lung Neoplasm, Hepatic Neoplasm (8270799-5)
Adverse event was reported on Mar 26, 2012 by a Male taking Imodium (Dosage: N/A) was diagnosed with
  • diarrhoea
and. Location: UNITED STATES , weighting 190.2 lb, Patient felt the following Imodium side effects: lung neoplasm, hepatic neoplasm.
Multiple prescriptions taken:
  • Fluorouracil
  • Leucovorin Calcium
  • Irinotecan Hydrochloride
  • Avastin
  • Lomotil
  • Oxaliplatin


Pain, Cholecystitis Chronic, Gallbladder Disorder, Injury, Nephrolithiasis, Emotional Distress, Anxiety, Renal Failure, Psychological Trauma (8269459-6)
on Mar 30, 2012 Female from UNITED STATES , 43 years of age, weighting 186.0 lb, was treated with Imodium. After Imodium was administered, patient encountered several Imodium side effects: pain, cholecystitis chronic, gallbladder disorder, injury, nephrolithiasis, emotional distress, anxiety, renal failure, psychological trauma. Imodium dosage: N/A.
Multiple concurrent drugs taken:
  • Singulair (10 Mg, Unk)
  • Acetaminophen W/ Codeine No. 3 (Unk)
  • Klor-con M20 (Unk)
  • Albuterol
  • Albuterol Sulfate (90 Mcg)
  • Nitrofurantoin (monohydrate/macrocrystals) (Unk)
  • Ibuprofen (600 Mg)
  • Flomax (0.4 Mg, Unk)


Fluid Retention, Weight Increased, Dehydration, Fatigue, Diarrhoea, Glomerular Filtration Rate Decreased, Dry Skin, Blood Glucose Increased, Periorbital Oedema (8263182-X)
on May 03, 2011 Female from UNITED STATES , 64 years of age, weighting 158.1 lb, was treated with Imodium. Directly after, patient experienced the unwanted or unexpected Imodium side effects: fluid retention, weight increased, dehydration, fatigue, diarrhoea, glomerular filtration rate decreased, dry skin, blood glucose increased, periorbital oedema. Imodium dosage: N/A.
Associated medications used:
  • Gleevec (400 Mg, Qd, Oral)
  • Magnesium (magnesium)
Patient was hospitalized.

Blood Glucose Increased, Faeces Discoloured, Constipation, Vomiting (8250393-2)
Patient was taking Imodium Multi-symptom Relief. Patient felt the following Imodium side effects: blood glucose increased, faeces discoloured, constipation, vomiting on Mar 23, 2012 from UNITED STATES Additional patient health information: Female , 56 years of age, weighting 135.0 lb, . Imodium Multi-symptom Relief dosage: N/A.
Multiple prescriptions taken:
  • Glipizide (Since 7 Months)


Ovarian Cyst (8245671-7)
Adverse event was reported on Mar 21, 2012 by a Female taking Imodium (Dosage: N/A) was diagnosed with
  • crohn's disease
and. Location: UNITED STATES , 41 years of age, After Imodium was administered, patient encountered several Imodium side effects: ovarian cyst.
Multiple concurrent drugs taken:
  • Tysabri
  • Zoloft
  • Vitamin D
Patient was hospitalized.

Metastatic Renal Cell Carcinoma, Blood Urine Present, Blood Pressure Increased, Skin Discolouration, Hypoaesthesia, Cerebrovascular Disorder, Rash, Peripheral Coldness, Muscular Weakness (8235539-4)
on Mar 19, 2012 Female from UNITED STATES , 74 years of age, weighting 178.0 lb, was treated with Imodium. Directly after, patient experienced the unwanted or unexpected Imodium side effects: metastatic renal cell carcinoma, blood urine present, blood pressure increased, skin discolouration, hypoaesthesia, cerebrovascular disorder, rash, peripheral coldness, muscular weakness. Imodium dosage: N/A.
Associated medications used:
  • Clonidine (0.1 Not Appl., Qd)
  • Oxycontin (20 Mg, Bid)
  • Diltiazem Hcl
  • Atenolol (100 Mg, Qd)
  • Nexavar (400 Mg, Bid)
  • Oxycodone Hcl (5 Mg, Unk)


Muscle Spasms, Deep Vein Thrombosis, Pulmonary Embolism, Injection Site Pain, Dyspnoea (8227435-3)
on Mar 16, 2012 Female from UNITED STATES , weighting 147.1 lb, was diagnosed with
  • crohn's disease
and was treated with Imodium. Patient felt the following Imodium side effects: muscle spasms, deep vein thrombosis, pulmonary embolism, injection site pain, dyspnoea. Imodium dosage: N/A.
Multiple prescriptions taken:
  • Humira
  • Tylenol
  • Humira (Loading Dose)
  • Canasa
  • Lialda (4 Tabs At Bedtime)
  • Humira
Patient was hospitalized.

Lung Neoplasm Malignant (8222159-0)
Patient was taking Imodium A-d. After Imodium was administered, patient encountered several Imodium side effects: lung neoplasm malignant on Mar 15, 2012 from UNITED STATES Additional patient health information: Male , 63 years of age, was diagnosed with
  • diarrhoea
  • lung neoplasm malignant
and. Imodium A-d dosage: N/A.

Intestinal Perforation (8216192-2)
Adverse event was reported on Mar 13, 2012 by a Male taking Imodium (Dosage: 4mg As Required) . Location: UNITED STATES , 65 years of age, Directly after, patient experienced the unwanted or unexpected Imodium side effects: intestinal perforation.
Associated medications used:
  • Votrient (800mg Per Day)
  • Naprosyn (375mg As Required)
  • Omeprazole (40mg Per Day)
  • Amlodipine (10mg Per Day)
  • Atenolol (25mg Per Day)
  • Potassium Phosphates (750mg Twice Per Day)
Patient was hospitalized.

Urinary Retention (8212246-5)
on Mar 08, 2012 Male from UNITED STATES , 74 years of age, weighting 240.0 lb, was treated with Imodium Multi-symptom Relief. Patient felt the following Imodium side effects: urinary retention. Imodium Multi-symptom Relief dosage: N/A.

Cerebrovascular Accident, Epistaxis, Aphasia, Hallucination, Herpes Zoster, Nightmare (8200343-X)
on Feb 27, 2012 Female from , 81 years of age, was treated with Imodium. After Imodium was administered, patient encountered several Imodium side effects: cerebrovascular accident, epistaxis, aphasia, hallucination, herpes zoster, nightmare. Imodium dosage: N/A.
Multiple concurrent drugs taken:
  • Calcium Carbonate
  • Citalopram Hydrobromide
  • Acyclovir (Intravenous Drip)
  • Lansoprazole
  • Alendronic Acid (alendronic Acid)
  • Gabapentin
  • Mirtazapine
Patient was hospitalized.

Cardiac Arrest, Scleroderma Renal Crisis (8190963-3)
Patient was taking Imodium. Directly after, patient experienced the unwanted or unexpected Imodium side effects: cardiac arrest, scleroderma renal crisis on Mar 02, 2012 from IRELAND Additional patient health information: Female , weighting 132.3 lb, . Imodium dosage: N/A.
Associated medications used:
  • Lansoprazole
  • Zofran
  • Actiq
  • Ventavis
  • Zopiclone
  • Oxycodone Hcl
  • Tracleer (62.5 Mg, Unk)
  • Mirtazapine
Patient was hospitalized.

Intentional Overdose, Ventricular Fibrillation (8184370-7)
Adverse event was reported on Feb 21, 2012 by a Female taking Imodium (Dosage: 140 Tablets, Daily) . Location: UNITED STATES , 43 years of age, Patient felt the following Imodium side effects: intentional overdose, ventricular fibrillation. Patient was hospitalized.

Nephrolithiasis, Injury, Pain, Anxiety, Renal Failure, Gallbladder Disorder, Psychological Trauma, Cholecystitis Chronic, Emotional Distress (8180189-1)
on Feb 23, 2012 Female from UNITED STATES , 43 years of age, weighting 186.0 lb, was treated with Imodium. After Imodium was administered, patient encountered several Imodium side effects: nephrolithiasis, injury, pain, anxiety, renal failure, gallbladder disorder, psychological trauma, cholecystitis chronic, emotional distress. Imodium dosage: N/A.
Multiple concurrent drugs taken:
  • Singulair (10 Mg, Unk)
  • Advair Diskus 100/50
  • Zyrtec (10 Mg, Unk)
  • Albuterol
  • Yaz (Unk)
  • Acetaminophen
  • Metamucil-2 (Unk)


Dysphagia, Suffocation Feeling, Oesophageal Disorder (8169863-0)
on Feb 20, 2012 Male from DENMARK , weighting 231.5 lb, was treated with Imodium. Directly after, patient experienced the unwanted or unexpected Imodium side effects: dysphagia, suffocation feeling, oesophageal disorder. Imodium dosage: N/A.

Showing 1-25 of 553 

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It is very important to keep track of all side effects and discuss them with your doctor. If you think you may have a medical emergency, call your doctor or 911 immediately.

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Imodium Information

Alternative IMODIUM Names:LOPERAMID

Active Ingredient: LOPERAMID

Imodium Dosage, Warnings, Usage.

Side Effects reported to FDA: 553. View Imodium Adverse Reports

Imodium safety alerts: No

Reported deaths: 26

Reported hospitalizations: 155

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