Innohep Side Effects
Innohep Safety Alerts
Innohep Reviews: View Innohep Adverse Event Reports: patient, 57 years of age, was diagnosed with haemodialysis and took Innohep Patient was hospitalized.

Have Your experienced Innohep Side Effects? You are not alone. Many patients report unusual symptoms after using Innohep. This forum raises awareness about Innohep Side Effects.

side effects
Home> Innohep> Innohep Side Effects
What Are Your Innohep Side Effects
Gastro Intestinal (1)
High Blood Pressure (1)
>>See All

Common Innohep Side Effects

top 5 Innohep|Gastro int|High blood adverse effects

Before Taking Innohep

Find Out How to Take Innohep

Managing Your Medicines

Tips for Taking Medicines Properly

Did You Have a Innohep Side Effect?

Yes, Severe
Yes, Moderate
Yes, Minor
No

How Effective is Innohep for You?

Exceeded Expectations
Effective
Somewhat Effective
Not Effective

Innohep Forum

Innohep Adverse Effect Reports (FDA)

Enter Unusual Symptoms or Side Effects:

Showing 1-25 of 773 

Fluid Overload, Cardiac Arrest, Hypoxia, Haemodialysis, Respiratory Distress, Feeling Cold, Sinus Tachycardia, Bronchospasm, Anaphylactic Reaction (8499679-7)
on Jun 13, 2012 Male patient from SWEDEN , 57 years of age, was diagnosed with
  • haemodialysis
and was treated with Innohep(View Usage). Patient experienced the following unwanted or unexpected effects: fluid overload, cardiac arrest (cardiac arrest Questions), hypoxia, haemodialysis, respiratory distress, feeling cold, sinus tachycardia, bronchospasm, anaphylactic reaction. Innohep dosage: N/A. Patient was hospitalized.

Deep Vein Thrombosis, Chest Pain, Pulmonary Embolism (8499678-5)
Patient was taking Innohep (View Usage). Patient had the following side effects: deep vein thrombosis (deep vein thrombosis Questions), chest pain (chest pain Questions), pulmonary embolism (pulmonary embolism Questions) on Jun 19, 2012 from FRANCE Additional patient health information: Male patient , 29 years of age, weighting 286.6 lb, was diagnosed with
  • thrombosis prophylaxis
and. Innohep dosage: 4500 Iu (4500 Iu, 1 In 1 D), Subcutaneous 18000 Iu (18000 Iu, 1 In 1 D), Subcutaneous.

Chest Pain, Thrombocytosis (8499666-9)
Adverse event was reported on Jun 26, 2012 by a Female patient taking Innohep (View Usage) (Dosage: N/A) was diagnosed with
  • prophylaxis
and. Location: FRANCE , 83 years of age, After Innohep was administered, patient had the following side effects: chest pain (chest pain Questions), thrombocytosis.
Patient was taking other medications: Patient was hospitalized.

Off Label Use, Thrombophlebitis Superficial (8474633-X)
on Jun 07, 2012 Female patient from MARTINIQUE , 68 years of age, weighting 127.9 lb, was diagnosed with
  • thrombophlebitis superficial
and was treated with Innohep (View Usage). Patient experienced the following unwanted or unexpected effects: off label use, thrombophlebitis superficial. Innohep dosage: 0.55 Ml (1 In 1 D), Subcutaneous.


Lung Infection, Haemoptysis (8419930-9)
on Jun 05, 2012 Female patient from SPAIN , weighting 145.5 lb, was diagnosed with and was treated with Innohep(View Usage). Patient had the following side effects: lung infection, haemoptysis. Innohep dosage: 0.5 Mg, Qd.
Patient was taking other medications: Patient was hospitalized.

Cardiac Failure, Haemoglobin Decreased (8419261-7)
Patient was taking Innohep (View Usage). After Innohep was administered, patient had the following side effects: cardiac failure, haemoglobin decreased on May 18, 2012 from GERMANY Additional patient health information: Male patient , 77 years of age, weighting 185.2 lb, was diagnosed with and. Innohep dosage: 1 In 1 D, Subcutaneous.
Patient was taking other medications:

Deep Vein Thrombosis (8382972-6)
Adverse event was reported on May 07, 2012 by a Female patient taking Innohep (View Usage) (Dosage: 4500 Iu (1 In 1 D), Subcutaneous) was diagnosed with
  • thrombosis prophylaxis
and. Location: FRANCE , 28 years of age, weighting 286.6 lb, Patient experienced the following unwanted or unexpected effects: deep vein thrombosis (deep vein thrombosis Questions).

Cerebral Haemorrhage, Convulsion, Intracranial Pressure Increased, Bulbar Palsy (8382955-6)
on May 08, 2012 Male patient from BRAZIL , 74 years of age, weighting 172.0 lb, was diagnosed with and was treated with Innohep (View Usage). Patient had the following side effects: cerebral haemorrhage, convulsion, intracranial pressure increased, bulbar palsy. Innohep dosage: 15000 Iu (15000 Iu, 1 In 1 D), Subcutaneous.
Patient was taking other medications:

Anaemia, Oesophagitis Ulcerative, Haematemesis, Off Label Use (8382898-8)
on May 15, 2012 Male patient from FRANCE , 76 years of age, was diagnosed with
  • phlebitis
  • prostate cancer metastatic
and was treated with Innohep(View Usage). After Innohep was administered, patient had the following side effects: anaemia, oesophagitis ulcerative, haematemesis, off label use. Innohep dosage: N/A.
Patient was taking other medications: Patient was hospitalized.

Intracranial Pressure Increased, Subdural Haematoma (8375992-9)
Patient was taking Innohep (View Usage). Patient experienced the following unwanted or unexpected effects: intracranial pressure increased, subdural haematoma on May 03, 2012 from FRANCE Additional patient health information: Male patient , 76 years of age, weighting 131.2 lb, was diagnosed with
  • knee arthroplasty
and. Innohep dosage: 0.45 Ml (0.45 Ml, 1 In 1 D), Subcutaneous.
Patient was taking other medications: Patient was hospitalized.

Asthma (8375988-7)
Adverse event was reported on May 09, 2012 by a Male patient taking Innohep (View Usage) (Dosage: (10000 Iu)) . Location: CANADA , 87 years of age, Patient had the following side effects: asthma (asthma Questions).

Device Malfunction (8362168-4)
on May 10, 2012 Male patient from FRANCE , weighting 83.78 lb, was diagnosed with
  • thrombosis prophylaxis
  • bone sarcoma
and was treated with Innohep (View Usage). After Innohep was administered, patient had the following side effects: device malfunction. Innohep dosage: Unk.
Patient was taking other medications: Patient was hospitalized.

Thrombosis (8349108-9)
on Apr 24, 2012 Male patient from FRANCE , 22 years of age, was treated with Innohep(View Usage). Patient experienced the following unwanted or unexpected effects: thrombosis. Innohep dosage: 4500 Iu,subcutaneous.

Arteriovenous Fistula Thrombosis (8349003-5)
Patient was taking Innohep (View Usage). Patient had the following side effects: arteriovenous fistula thrombosis on Apr 22, 2012 from ALGERIA Additional patient health information: Female patient , 57 years of age, weighting 154.3 lb, was diagnosed with
  • thrombosis in device
and. Innohep dosage: 4500 Iu (4500 Iu,1 In 1 Total),intravenous. Patient was hospitalized.

Thrombosis In Device (8328009-6)
Adverse event was reported on Apr 13, 2012 by a Male patient taking Innohep (View Usage) (Dosage: 0, 35ml) was diagnosed with and. Location: UNITED ARAB EMIRATES , 50 years of age, weighting 145.5 lb, After Innohep was administered, patient had the following side effects: thrombosis in device.

Thrombosis In Device (8327997-1)
on Apr 13, 2012 Female patient from UNITED ARAB EMIRATES , 58 years of age, weighting 173.1 lb, was diagnosed with and was treated with Innohep (View Usage). Patient experienced the following unwanted or unexpected effects: thrombosis in device. Innohep dosage: 0, 35ml.

Thrombosis In Device (8327996-X)
on Apr 13, 2012 Male patient from UNITED ARAB EMIRATES , 50 years of age, weighting 121.3 lb, was diagnosed with and was treated with Innohep(View Usage). Patient had the following side effects: thrombosis in device. Innohep dosage: 0, 35 Ml.

Thrombosis In Device (8327995-8)
Patient was taking Innohep (View Usage). After Innohep was administered, patient had the following side effects: thrombosis in device on Apr 13, 2012 from UNITED ARAB EMIRATES Additional patient health information: Male patient , 35 years of age, weighting 146.6 lb, was diagnosed with and. Innohep dosage: 0, 35ml.

Thrombosis In Device (8327992-2)
Adverse event was reported on Apr 13, 2012 by a Male patient taking Innohep (View Usage) (Dosage: 0, 35ml) was diagnosed with and. Location: UNITED ARAB EMIRATES , 70 years of age, weighting 149.9 lb, Patient experienced the following unwanted or unexpected effects: thrombosis in device.

Pulmonary Embolism (8321731-7)
on Apr 18, 2012 Male patient from FRANCE , 44 years of age, was diagnosed with
  • prophylaxis
and was treated with Innohep (View Usage). Patient had the following side effects: pulmonary embolism (pulmonary embolism Questions). Innohep dosage: Preventative Dosage (1 In 1 D), Subcutaneous.

Deep Vein Thrombosis, Maternal Exposure During Pregnancy (8321718-4)
on Apr 17, 2012 Female patient from FRANCE , 38 years of age, weighting 330.7 lb, was diagnosed with and was treated with Innohep(View Usage). After Innohep was administered, patient had the following side effects: deep vein thrombosis (deep vein thrombosis Questions), maternal exposure during pregnancy. Innohep dosage: (1 In 1 D), Subcutaneous. Patient was hospitalized.

Cardio-respiratory Arrest, Underdose, Pulmonary Embolism (8313210-8)
Patient was taking Innohep (View Usage). Patient experienced the following unwanted or unexpected effects: cardio-respiratory arrest, underdose, pulmonary embolism (pulmonary embolism Questions) on Mar 09, 2012 from SYRIAN ARAB REPUBLIC Additional patient health information: Female patient , 20 years of age, was diagnosed with and. Innohep dosage: 0.45 Ml Then Changed To 0.6 (1 In 1 D). Patient was hospitalized.

Oesophagitis Ulcerative, Haematemesis, Anaemia, Phlebitis (8313204-2)
Adverse event was reported on Apr 13, 2012 by a Male patient taking Innohep (View Usage) (Dosage: N/A) was diagnosed with
  • phlebitis
  • prostate cancer metastatic
and. Location: FRANCE , 76 years of age, Patient had the following side effects: oesophagitis ulcerative, haematemesis, anaemia, phlebitis.
Patient was taking other medications: Patient was hospitalized.

Agitation, Muscle Tightness, Restlessness, Discomfort, Feeling Abnormal (8313041-9)
on Apr 12, 2012 Female patient from UNITED KINGDOM , 73 years of age, weighting 145.5 lb, was treated with Innohep (View Usage). After Innohep was administered, patient had the following side effects: agitation, muscle tightness, restlessness, discomfort, feeling abnormal. Innohep dosage: 2500 Iu,intravenous.
Patient was taking other medications:

Gastritis, Duodenitis Haemorrhagic, Asthenia, White Blood Cell Count Increased, Gastrointestinal Haemorrhage, Abdominal Pain, Prothrombin Time Prolonged, Anaemia (8295727-8)
on Mar 29, 2012 Female patient from INDIA , 41 years of age, weighting 84.22 lb, was diagnosed with and was treated with Innohep(View Usage). Patient experienced the following unwanted or unexpected effects: gastritis, duodenitis haemorrhagic, asthenia, white blood cell count increased, gastrointestinal haemorrhage, abdominal pain (abdominal pain Questions), prothrombin time prolonged, anaemia. Innohep dosage: 8000 Iu (8000 Iu,1 In 1 D),subcutaneous ; 8000 Iu (8000 Iu,1 In 1 D),subcutaneous. Patient was hospitalized.

Showing 1-25 of 773 

Share Your Experience, Discuss with Others

Innohep Information

Alternative INNOHEP Names:TINZAPARI

Substance:TINZAPARI

Innohep Dosage, Warnings, Usage.

Side Effects reported to FDA: 773. View FDA Adverse Reports

Innohep safety alerts: 2008

Reported deaths: 116

Reported hospitalizations: 416

1Gastro Intestinal
2High Blood Pressure
View More

Ask a Doctor


13 Doctors are Online Now. Current Wait time: 7 Minutes

View Innohep Use Reports

What do You think about Innohep? Join the discussion!

blog comments powered by Disqus

Medicines have benefits and risks. The risks are the chances that something unwanted or unexpected could happen to you when you use them. You can protect yourself by searching summaries of recent safety Innohep alerts and medication adverse reports. Search for documented Innohep side effects on the label or the drug's package insert. You may also want to speak with your pharmacist or healthcare provider. Sometimes there are risks that only come to light after a medical product gets on the market and is used in a larger number of patients, for a longer period of time, and in patients whose health characteristics are different from those of the patients studied before approval.

Go to the top of the page

Innohep (tinzaparin sodium injection)

Audience: Hematological and Nephrological healthcare professionals, hospital risk managers

[UPDATE 12/31/2008] Celgene has issued a Dear Healthcare Professional letter describing a controlled clinical study suggesting that Innohep may increase the risk for death, compared to unfractionated heparin when used to treat elderly patients with renal insufficiency. It recommended consideration of alternatives to Innohep when treating these patients for deep vein thrombosis with or without pulmonary embolism.

[Posted 12/02/2008] FDA has received information about the clinical study: Innohep in Renal Insufficiency Study (IRIS) that was stopped in February, 2008 by the studyâ??s Data Safety Monitoring Committee because of an interim finding of an increase in all-cause mortality in patients who received Innohep. Information on the patients enrolled in the study, on the heparin used to manufacture Innohep, and on the heparin used in the study is still being collected and analyzed.

In July 2008, the company revised the prescribing information to restrict the use of Innohep in patients 90 years of age or older. FDA is concerned that the preliminary data from the IRIS study suggest that the increased risk of mortality is not limited only to patients 90 years of age or older. Therefore, FDA has requested that the company revise the labeling for Innohep to better describe the overall study results which suggest that, when compared to unfractionated heparin, Innohep increases the risk of death for elderly patients (i.e., 70 years of age and older) with renal insufficiency. Healthcare professionals should consider the use of alternative treatments to Innohep when treating elderly patients over 70 years of age with renal insufficiency and DVT, PE, or both. This communication is in keeping with FDAâ??s commitment to inform the public about its ongoing safety reviews of drugs. FDA anticipates submission of the final IRIS study report in January, 2009 and plans to complete its review soon thereafter. FDA will communicate its conclusions and any resulting recommendations to the public at that time. FDA will consider additional regulatory actions as appropriate after thorough review of all applicable data from the manufacturer of Innohep.

[December 02, 2008 - Communication about an Ongoing Safety Review - FDA]
[December 31, 2008 - Dear Healthcare Professional letter - Celgene]

further research and contacting my doctor

When did you start feeling unusual symptoms? what was the first symptom? Did your symptoms get worse over time? Did you have similar symptoms before using Innohep? What did Your doctor say? Share Your Story

> Medical Devices

Reply to Innohep Questions, Answers, Feedback and Comments

No comments have been provided.

Innohep Adverse Reactions
Pulmonary Embolism ( 97 Reports) Pulmonary embolism Questions
Premature Baby ( 84 Reports)
Caesarean Section ( 65 Reports)
Deep Vein Thrombosis ( 62 Reports) Deep vein thrombosis Questions
Off Label Use ( 53 Reports)
Heparin-induced Thrombocytopenia ( 48 Reports)
Anaemia ( 31 Reports)
Premature Labour ( 27 Reports)
Haemoglobin Decreased ( 26 Reports)
Postpartum Haemorrhage ( 25 Reports)
Haematoma ( 22 Reports)
Overdose ( 22 Reports)
Dyspnoea ( 21 Reports)
International Normalised Ratio Increased ( 16 Reports)
Premature Separation Of Placenta ( 16 Reports)
Condition Aggravated ( 15 Reports)
Haemorrhage ( 15 Reports)
Nausea ( 15 Reports) Nausea Questions
Renal Failure ( 15 Reports)
Thrombocytopenia ( 15 Reports)
Thrombosis ( 15 Reports)
Asthenia ( 14 Reports)
Disease Recurrence ( 13 Reports)
Malaise ( 13 Reports)
Abdominal Pain ( 12 Reports) Abdominal pain Questions
Abortion Spontaneous ( 12 Reports)
Apgar Score Low ( 12 Reports)
Gastrointestinal Haemorrhage ( 12 Reports)
Thrombosis In Device ( 12 Reports)
Cardiac Arrest ( 11 Reports) Cardiac arrest Questions

Often additional risks of using a medication, such as Innohep, become known after product is used by a larger number of patients, for a longer period of time, and by patients with different health characteristics from those studied before drug approval. This page allows You to Find answers and discuss health symptoms with other Innohep users, Learn more about unwanted side effects & find ways to reduce them. Browse Innohep Adverse Reports reported to FDA and participate in Innohep discussion, find alternative treatments and find ways to avoid or reduce risks associated with using Innohep. You can also Post a question to users community or Ask a Doctor. PatientsVille.com is Your Complete Guide to all common, undocumented and undisclosed side effects associated with drugs and vaccines.

Be aware of the following potential Innohep risks:

  • Watch for any Serious adverse events, such as life-threatening situation, which can require an admission to hospital or longer-than-expected hospital stay, permanent disability, birth defect, miscarriage, stillbirth, or birth with serious disease requires medical care to prevent permanent damage
  • Any potential Innohep quality problem: suspected counterfeit product, potentially contaminated product indicated by suspicious odor or unusual color, inaccurate or unreadable product labeling
  • Potential Innohep use error: mixing up products with similar drug names or packaging, taking wrong dose of a drug because of confusing dosing instructions on label
  • When applicable, Problems with different manufacturer of same medicine: not getting same results from a generic drug as a brand name drug, or from another generic

side effects
Innohep Side Effects Notice - The material on this site is for informational purposes only, and is not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. PatientsVille.com does not provide medical advice, diagnosis or treatment. The information regarding Innohep adverse reports, reviews and polls contained on PatientsVille.com site has not been scientifically or otherwise verified as to a cause and effect relationship and cannot be used to estimate the incidence of adverse drug reactions or for establishing or changing of patient treatments. Thank you for visiting Patientsville.com!