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Inspra Safety Reports

Total Inspra reports: 39.
Inspra FDA safety alerts: No.
Reported deaths: 11    Reported hospitalizations: 13.
Take Inspra Side Effects Survey or Share Your Inspra Story.
Reported Inspra Side Effects: blood glucose increased, dialysis, fall, cerebral haemorrhage, hypertension, renal failure acute, hyperhidrosis, depression, atrial fibrillation, renal failure, cardiac arrest.
Inspra Usage.

Inspra Side Effects Report #5202620-3
Physician from GERMANY reported INSPRA problem on Jan 02, 2007. Male patient was diagnosed with congestive cardiomyopathy and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: acute hepatic failure, cardiac arrest, constipation, dialysis, renal failure, right ventricular failure. INSPRA dosage: DAILY DOSE:50MG. During the same period patient was treated with SPIRONOLACTONE, RAMIPRIL, ASPIRIN, SIMVASTATIN, AMIODARONE, PANTOZOL, TORSEMIDE. Patient died on 12/05/2006.

Inspra Side Effects Report #5207831-9
INSPRA problem was reported by a Health Professional from FRANCE on Jan 04, 2007. Male patient, 67 years of age, weighting 185.2 lb, was diagnosed with ischaemic cardiomyopathy, cardiac failure and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: hyperbilirubinaemia, jaundice, reticulocytosis. INSPRA dosage: DAILY DOSE:25MG-FREQ:EVERY DAY. During the same period patient was treated with FLUOXETINE HYDROCHLORIDE, RAMIPRIL, ASPIRIN, PRAVASTATIN, BISOPROLOL FUMARATE, FLUINDIONE, AMIODARONE HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Inspra Side Effects Report #5254480-2
Physician from FRANCE reported INSPRA problem on Feb 20, 2007. Male patient, weighting 160.9 lb, was diagnosed with primary hyperaldosteronism, atrial fibrillation and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, diabetes mellitus inadequate control. INSPRA dosage: unknown. During the same period patient was treated with CORDARONE, AMLODIPINE, OLMETEC, LOPRESSOR, GLICLAZIDE. Patient recovered.

Inspra Side Effects Report #5266585-0
INSPRA problem was reported by a Consumer or non-health professional from GERMANY on Mar 06, 2007. Male patient, 72 years of age, was diagnosed with cardiac failure and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: blood glucose increased, increased insulin requirement. INSPRA dosage: unknown. During the same period patient was treated with INSULIN, LANTUS, ALDACTONE, TORSEMIDE. Patient recovered.

Inspra Side Effects Report #5269386-2
Physician from FRANCE reported INSPRA problem on Mar 07, 2007. Male patient, 55 years of age, was diagnosed with cardiomyopathy and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: platelet count decreased. INSPRA dosage: unknown. During the same period patient was treated with TAHOR, KREDEX, MAGNESIUM SULPHATE, KARDEGIC, PERINDOPRIL ERBUMINE. Patient recovered.

Inspra Side Effects Report #5288956-9
INSPRA problem was reported by a Physician from GERMANY on Mar 27, 2007. Male patient, weighting 165.3 lb, was diagnosed with cardiac failure and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: acute coronary syndrome, priapism, urethral haemorrhage. INSPRA dosage: DAILY DOSE:50MG-FREQ:DAILY. During the same period patient was treated with COVERSUM, ASPIRIN, VERAPAMIL, SIMVASTATIN, DOXAZOSIN MESYLATE, SPIRONOLACTONE, ENAHEXAL. Patient was hospitalized. Patient recovered.

Inspra Side Effects Report #5310660-9
Physician from FRANCE reported INSPRA problem on Apr 18, 2007. Male patient, 42 years of age, was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: malaise, tinnitus, vertigo. INSPRA dosage: unknown. During the same period patient was treated with ACENOCOUMAROL, DIGOXIN, RAMIPRIL, ATORVASTATIN CALCIUM, FUROSEMIDE. Patient recovered.

Inspra Side Effects Report #5317279-4
INSPRA problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 24, 2007. Male patient, weighting 164.9 lb, was diagnosed with hypertension and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: depression, muscle spasms, myalgia, nightmare, vitamin d deficiency. INSPRA dosage: unknown. During the same period patient was treated with ACETYLSALICYLIC ACID SRT. Patient recovered.

Inspra Side Effects Report #5322723-2
Physician from GERMANY reported INSPRA problem on May 02, 2007. Male patient, 42 years of age, weighting 205.0 lb, was diagnosed with cardiac failure and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: blood glucose increased, hyperhidrosis, visual disturbance. INSPRA dosage: DAILY DOSE:25MG-FREQ:DAILY. During the same period patient was treated with CARVEDILOL, MARCUMAR, NITROGLYCERIN, DIGITOXIN, RAMIPRIL, TORSEMIDE. Patient was hospitalized. Patient recovered.

Inspra Side Effects Report #5330341-5
INSPRA problem was reported by a Physician from GERMANY on May 10, 2007. Female patient was diagnosed with cardiac failure, cardiac arrest and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: autoimmune thyroiditis, hypothyroidism, oligomenorrhoea. INSPRA dosage: DAILY DOSE:50MG-FREQ:DAILY. During the same period patient was treated with BETA BLOCKING AGENTS, ACE INHIBITOR NOS. Patient recovered.

Inspra Side Effects Report #5349856-9
Physician from GERMANY reported INSPRA problem on May 29, 2007. Male patient, weighting 220.5 lb, was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: gynaecomastia, haematuria. INSPRA dosage: unknown. During the same period patient was treated with OSYROL, METOPROLOL SUCCINATE, RAMIPRIL, TORSEMIDE, EZETROL, MARCUMAR, FRAGMIN. Patient recovered.

Inspra Side Effects Report #5375562-0
INSPRA problem was reported by a Health Professional from GERMANY on June 19, 2007. Female patient, weighting 145.5 lb, was diagnosed with cardiac failure and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: acute hepatic failure, coagulopathy, haemorrhage, renal failure acute, thrombocytopenia. INSPRA dosage: unknown. During the same period patient was treated with HYDROCHLOROTHIAZIDE, LEVOTHYROXINE, ACETYLSALICYLIC ACID SRT, FUROSEMIDE, BISOPROLOL, ACTRAPHANE. Patient died on 01/23/2007.

Inspra Side Effects Report #5062928-1
Physician from GERMANY reported INSPRA problem on July 13, 2006. Male patient was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: cerebrovascular accident. INSPRA dosage: unknown. Patient died.

Inspra Side Effects Report #5074146-1
INSPRA problem was reported by a Physician from UNITED KINGDOM on July 24, 2006. Male patient, 66 years of age, weighting 134.5 lb, was diagnosed with cardiac failure and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: cardiac arrest, cardiac disorder, fall, hypertension, hypoaesthesia, hypoxic encephalopathy, paraesthesia, ventricular fibrillation. INSPRA dosage: 12.5 MG (12.5 MG, DAILY: EVERY DAY), ORAL. During the same period patient was treated with BUMETANIDE, BENDROFLUMETHIAZIDE, ENALAPRIL MALEATE, NICORANDIL, CLOPIDOGREL, CARVEDILOL, SERETIDE, SALBUTAMOL. Patient died on 05/11/2006.

Inspra Side Effects Report #5099794-4
Physician from GERMANY reported INSPRA problem on Aug 23, 2006. Male patient, 73 years of age, weighting 165.3 lb, was diagnosed with cardiac failure and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: cardiac failure, condition aggravated, dialysis, dizziness, leukocytosis, lymphopenia, neutrophil count increased, pneumonia, renal failure acute. INSPRA dosage: unknown. During the same period patient was treated with BISOPROLOL FUMARATE, TOREM, MARCUMAR, ALLOPURINOL, SIMVASTATIN, DIGITOXIN. Patient died on 07/06/2006.

Inspra Side Effects Report #5115116-4
INSPRA problem was reported by a Consumer or non-health professional from UNITED STATES on Sept 11, 2006. Female patient, 88 years of age, was diagnosed with blood pressure and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: dyskinesia, malaise, swollen tongue. INSPRA dosage: 25 MG (25 MG, FREQUENCY: QD INTERVAL: EVERY DAY). During the same period patient was treated with DIOVAN, PLAVIX, DEMADEX, ACETYLSALICYCLIC AICD, ALLOPURINOL, HYDROXYUREA. Patient recovered.

Inspra Side Effects Report #5117096-4
Physician from GERMANY reported INSPRA problem on Sept 12, 2006. Male patient, 42 years of age, was diagnosed with cardiac failure and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: blood glucose increased, hyperhidrosis, visual disturbance. INSPRA dosage: 25 MG (DAILY), ORAL; 3 WEEKS AGO. During the same period patient was treated with CARVEDILOL, MARCUMAR, NITROGLYCERIN, DIGITOXIN, RAMIPRIL. Patient was hospitalized. Patient recovered.

Inspra Side Effects Report #5117104-0
INSPRA problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Aug 14, 2006. Male patient, 54 years of age, was diagnosed with cardiac failure chronic and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: asthenia, cellulitis, cholecystitis acute, coordination abnormal, dehydration, dyskinesia, dyspnoea, exercise test abnormal, hyperhidrosis. INSPRA dosage: (25 MG), ORAL. Patient was hospitalized. Patient recovered.

Inspra Side Effects Report #5117182-9
Consumer or non-health professional from UNITED STATES reported INSPRA problem on Sept 14, 2006. Female patient, 72 years of age, weighting 140.0 lb, was diagnosed with hypertension, diabetes mellitus, arrhythmia and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: angioneurotic oedema, arrhythmia, blood glucose increased, hypersensitivity, hypertension, treatment noncompliance. INSPRA dosage: 100 MG (50 MG, BID); ORAL. During the same period patient was treated with GLIBENCLAMIDELET, LANOXIN, METHYLDOPA. Patient was hospitalized. Patient recovered.

Inspra Side Effects Report #5123441-6
INSPRA problem was reported by a Physician from FRANCE on Sept 22, 2006. Male patient was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: gynaecomastia, haemolysis, jaundice. INSPRA dosage: 25 MG. During the same period patient was treated with ALDACTONE, CARDENSIEL, RAMIPRIL, LASIX, PRAVASTATIN, ASPIRIN. Patient recovered.

Inspra Side Effects Report #5130026-4
Physician from GERMANY reported INSPRA problem on Oct 02, 2006. Male patient was diagnosed with cardiac failure congestive and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, cerebral haemorrhage, confusional state, fall, refusal of treatment by patient, renal failure. INSPRA dosage: 25 MG (25 MG, FREQUENCY: DAILY), ORAL. During the same period patient was treated with CARMEN, METOPROLOL TARTRATE, CANDESARTAN, MARCUMAR. Patient was hospitalized. Patient died.

Inspra Side Effects Report #5202536-2
INSPRA problem was reported by a Physician from UNITED STATES on Nov 14, 2005. Female patient, 58 years of age, weighting 120.0 lb, was diagnosed with hypertension and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: blood potassium increased. INSPRA dosage: 25 MG (25 MG, 1 IN 24 HR) ORAL. During the same period patient was treated with FOSAMAX, LIPITOR, VITAMIN CAP, ASPIRIN, BISOPROLOL FUMARATE. Patient recovered.

Inspra Side Effects Report #5165528-8
Health Professional from GERMANY reported INSPRA problem on Nov 10, 2006. Male patient, 55 years of age, was diagnosed with cardiac failure and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation. INSPRA dosage: unknown. During the same period patient was treated with LORZAAR PLUS, BISOPROLOL FUMARATE, EZETIMIBE. Patient was hospitalized. Patient recovered.

Inspra Side Effects Report #5165538-0
INSPRA problem was reported by a Physician from GERMANY on Nov 10, 2006. Male patient, 71 years of age, was diagnosed with cardiac failure and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: blood glucose increased. INSPRA dosage: 25 MG (25 MG, DAILY), ORAL. During the same period patient was treated with INSULIN, BETA BLOCKING AGENTS, MARCUMAR, DIGITALIS CAP. Patient recovered.

Inspra Side Effects Report #5170364-2
Physician from GERMANY reported INSPRA problem on Nov 27, 2006. Male patient, 80 years of age, weighting 187.4 lb, was diagnosed with cardiac failure and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: cerebral haemorrhage, dialysis, fall, renal failure, somnolence, traumatic brain injury. INSPRA dosage: 25 MG, ORAL. During the same period patient was treated with ANGIOTENSIN II ANTAGONISTS, BETA BLOCKING AGENTS, DIURETICS. Patient died.

Inspra Side Effects Report #5170633-6
INSPRA problem was reported by a Consumer or non-health professional from GERMANY on Nov 22, 2006. Male patient, 72 years of age, was diagnosed with cardiac failure and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: blood glucose increased, increased insulin requirement. INSPRA dosage: unknown. During the same period patient was treated with INSULIN, LANTUS, ALDACTONE, UNAT, TORSEMIDE. Patient recovered.

Inspra Side Effects Report #5186948-1
Physician from UNITED STATES reported INSPRA problem on Dec 01, 2006. Female patient, 72 years of age, weighting 140.0 lb, was diagnosed with hypertension, diabetes mellitus, arrhythmia and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: angioneurotic oedema, arrhythmia, blood glucose increased, hypersensitivity, hypertension. INSPRA dosage: 100 MG (50 MG, BID), ORAL. During the same period patient was treated with GLYBURIDE, LANOXIN, METHYLDOPA, ALDOMET, CALCIUM, MAGNESIUM, VITAMIN D. Patient was hospitalized. Patient recovered.

Inspra Side Effects Report #5189880-2
INSPRA problem was reported by a Physician from GERMANY on Dec 07, 2006. Male patient, 80 years of age, weighting 187.4 lb, was diagnosed with cardiac failure and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: cerebral haemorrhage, condition aggravated, dialysis, fall, nephropathy toxic, renal failure chronic, somnolence, traumatic brain injury. INSPRA dosage: 25 MG, ORAL. During the same period patient was treated with ANGIOTENSIN II ANTAGONISTS, BETA BLOCKING AGENTS, DIURETICS, ATACAND, MARCUMAR, BISOPROLOL FUMARATE, SIMVASTATIN, NORVASC. Patient died.

Inspra Side Effects Report #5191180-1
Physician from GERMANY reported INSPRA problem on Dec 06, 2006. Male patient, 78 years of age, was diagnosed with congestive cardiomyopathy and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: cardiac arrest, constipation, dialysis, diarrhoea, hepatic failure, renal failure. INSPRA dosage: 50 MG, ORAL. During the same period patient was treated with SPIRONOLACTONE, RAMIPRIL, ACETYLSALICYLIC ACID SRT, SIMVASTATIN, AMIODARONE, PANTOZOL, TORSEMIDE. Patient died on 12/05/2006.

Inspra Side Effects Report #5194386-0
INSPRA problem was reported by a Physician from FRANCE on Dec 19, 2006. Male patient, 70 years of age, was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: anuria, circulatory collapse. INSPRA dosage: unknown. During the same period patient was treated with CARDENSIEL. Patient died.

Inspra Side Effects Report #5195213-8
Pharmacist from IRELAND reported INSPRA problem on Oct 20, 2006. Male patient, 71 years of age, weighting 160.1 lb, was diagnosed with blood pressure abnormal and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: arthritis, muscle strain, oedema peripheral. INSPRA dosage: unknown. During the same period patient was treated with LISINOPRIL, NEBIVOLOL, FELODIPINE. Patient recovered.

Inspra Side Effects Report #5197662-0
INSPRA problem was reported by a Pharmacist from IRELAND on Dec 14, 2006. Male patient, 71 years of age, weighting 160.1 lb, was diagnosed with blood pressure abnormal and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: arthritis. INSPRA dosage: unknown. During the same period patient was treated with LISINOPRIL, NEBIVOLOL, FELODIPINE. Patient recovered.

Inspra Side Effects Report #5377730-0
Health Professional from FRANCE reported INSPRA problem on June 21, 2007. Male patient, 82 years of age, was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: aplastic anaemia, neutropenia. INSPRA dosage: unknown. During the same period patient was treated with LASIX, CARDENSIEL, PERINDOPRIL ERBUMINE, ASPIRIN, IKOREL, VASTAREL, AMLODIPINE, PRAVASTATIN. Patient was hospitalized. Patient recovered.

Inspra Side Effects Report #5379322-6
INSPRA problem was reported by a Physician from GERMANY on June 26, 2007. Female patient, weighting 138.9 lb, was diagnosed with cardiac failure, myocardial infarction and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: depression, gastrointestinal disorder. INSPRA dosage: DAILY DOSE:25MG. During the same period patient was treated with NEBILET, CORDARONE, SIMVASTATIN. Patient was hospitalized. Patient recovered.

Inspra Side Effects Report #5382306-5
Physician from UNITED STATES reported INSPRA problem on June 29, 2007. Male patient, weighting 164.9 lb, was diagnosed with hypertension and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: depression, muscle spasms, myalgia, nightmare, vitamin d deficiency. INSPRA dosage: unknown. During the same period patient was treated with ASPIRIN. Patient recovered.

Inspra Side Effects Report #5384584-5
INSPRA problem was reported by a Physician from GERMANY on July 02, 2007. Female patient, weighting 145.5 lb, was diagnosed with myocardial infarction, cardiac failure and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: acute hepatic failure, coagulopathy, haemorrhage, nausea, renal failure acute, thrombocytopenia. INSPRA dosage: unknown. During the same period patient was treated with ASPIRIN, BISOPROLOL, LASIX, LEVOTHYROXINE, GODAMED, ACTRAPHANE. Patient was hospitalized. Patient died on 01/23/2007.

Inspra Side Effects Report #5405392-2
Physician from FRANCE reported INSPRA problem on Apr 20, 2007. Male patient, 55 years of age, was diagnosed with cardiomyopathy and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: platelet count decreased. INSPRA dosage: unknown. During the same period patient was treated with TAHOR, KREDEX, MAGNESIUM SULPHATE, KARDEGIC, PERINDOPRIL ERBUMINE. Patient recovered.

Inspra Side Effects Report #5408838-9
INSPRA problem was reported by a Health Professional from UNITED KINGDOM on July 27, 2007. Male patient, 79 years of age, weighting 191.8 lb, was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: dizziness, gait disturbance, headache, renal impairment. INSPRA dosage: TEXT:25MG. Patient was hospitalized and became disabled. Patient recovered.

Inspra Side Effects Report #5463544-X
Physician from UNITED KINGDOM reported INSPRA problem on Sept 04, 2007. Male patient, 69 years of age, weighting 220.5 lb, was diagnosed with cardiac failure and was treated with INSPRA. After drug was administered, patient experienced the following problems/side effects: psoriasis. INSPRA dosage: unknown. During the same period patient was treated with ASPIRIN, FUROSEMIDE, RAMIPRIL, ATORVASTATIN CALCIUM, ATENOLOL. Patient recovered.


Drug Information: Eplerenone

URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a603004.html

e pler' en one

Why is this medication prescribed?

Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.

How should this medicine be used?

Eplerenone comes as a tablet to take by mouth. It is usually taken once or twice a day, with or without food. To help you remember to take eplerenone, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take eplerenone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor may start you on a low dose of eplerenone and increase your dose after 4 weeks.

Eplerenone controls high blood pressure but does not cure it. It may take 4 weeks or longer before you feel the full benefit of eplerenone. Continue to take eplerenone even if you feel well. Do not stop taking eplerenone without talking to your doctor.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking eplerenone,

  • tell your doctor and pharmacist if you are allergic to eplerenone or any other medications.
  • do not take eplerenone if you are taking amiloride (Midamor), amiloride and hydrochlorothiazide (Moduretic), itraconazole (Sporanox), ketoconazole (Nizoral), potassium supplements, spironolactone (Aldactone), spironolactone and hydrochlorothiazide (Aldactazide), triamterene (Dyrenium), or triamterene and hydrochlorothiazide (Dyazide, Maxzide).
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking. Be sure to mention any of the following: angiotensin converting enzyme (ACE) inhibitors such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), and quinapril (Accupril); angiotensin II receptor antagonists such as eprosartan (Teveten), irbesartan (Avapro), losartan (Cozaar), olmesartan (Benicar), and valsartan (Diovan); aspirin and other nonsteroidal anti-inflammatory medications (NSAIDS) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); cimetidine (Tagamet); clarithromycin (Biaxin); danazol (Danocrine); delavirdine (Rescriptor); diltiazem (Cardizem, Dilacor, Tiazac); erythromycin (E.E.S., E-Mycin, Erythrocin); fluconazole (Diflucan); fluoxetine (Prozac, Sarafem); fluvoxamine (Luvox); HIV protease inhibitors such as indinavir (Crixivan), ritonavir (Norvir), and saquinavir (Fortovase, Invirase); isoniazid (INH, Nydrazid); lithium (Eskalith, Lithobid), metronidazole (Flagyl); nefazodone (Serzone); troleandomycin (TAO); verapamil (Calan, Covera, Isoptin, Verelan); and zafirlukast (Accolate). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor what herbal products you are taking, especially St. John' wort.
  • tell your doctor if you have or have ever had high blood levels of potassium, diabetes, gout, or liver or kidney disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking eplerenone, call your doctor.

What special dietary instructions should I follow?

Talk to your doctor about drinking grapefruit juice while taking this medicine.

Do not use salt substitutes containing potassium while you are taking eplerenone. If your doctor prescribes a low-salt or low-sodium diet, follow these directions carefully.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Eplerenone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • headache
  • dizziness
  • diarrhea
  • stomach pain
  • cough
  • excessive tiredness
  • flu-like symptoms
  • breast enlargement or tenderness
  • abnormal vaginal bleeding

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:

  • chest pain
  • tingling in arms and legs
  • loss of muscle tone
  • weakness or heaviness in legs
  • confusion
  • lack of energy
  • cold, gray skin
  • irregular heartbeat

Eplerenone may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:

  • fainting
  • dizziness
  • blurred vision
  • upset stomach
  • tingiling in arms and legs
  • loss of muscle tone
  • weakness or heaviness in legs
  • confusion
  • lack of energy
  • cold, gray skin
  • irregular or slow heartbeat

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will check your blood pressure regularly and order certain lab tests to check your body's response to eplerenone.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand name(s):

  • Inspra®

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