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Fatigue (8)
Hip Pain (6)
Itching (6)
Neuropathy (6)
Joint Pain (5)
Cough (4)
Neutropenia (4)
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Ipilimumab Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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  Showing 51-75 of 617 

Multi-organ Failure, Nausea (8388730-0)
on May 21, 2012 Female from GERMANY , 80 years of age, weighting 154.3 lb, was diagnosed with
  • malignant melanoma
and was treated with Ipilimumab. Directly after, patient experienced the unwanted or unexpected Ipilimumab side effects: multi-organ failure, nausea. Ipilimumab dosage: N/A.
Associated medications used:
  • Demadex
  • Haloperidol
  • Sodium Chloride (1df= 0.9%)
  • Pantoprazole
  • Dimenhydrinate
  • Dexamethasone
Patient was hospitalized.

Nausea, Rash, Uveitis, Alopecia, Pruritus, Autoimmune Hepatitis, Hypotension, Vomiting, Dehydration (8372408-3)
Patient was taking Ipilimumab. Patient felt the following Ipilimumab side effects: nausea, rash, uveitis, alopecia, pruritus, autoimmune hepatitis, hypotension, vomiting, dehydration on May 09, 2012 from IRELAND Additional patient health information: Female , 35 years of age, was diagnosed with
  • malignant melanoma
and. Ipilimumab dosage: Total Cycle:4 Each Cycle Each Month,01dec09-01dec09,900mg,no.of Courses:4.
Multiple prescriptions taken:
  • Domperidone
  • Permixon
  • Tramadol Hydrochloride
  • Pregabalin
  • Acetaminophen
  • Cyclizine
Patient was hospitalized.

Sarcoidosis (8371050-8)
Adverse event was reported on May 08, 2012 by a Female taking Ipilimumab (Dosage: Total 4 Administration Planned.) was diagnosed with
  • metastatic malignant melanoma
and. Location: BELGIUM , 48 years of age, weighting 218.3 lb, After Ipilimumab was administered, patient encountered several Ipilimumab side effects: sarcoidosis.

Vomiting, Emotional Distress, Neoplasm Malignant, Colitis, Diarrhoea, Abdominal Pain Upper, Polyneuropathy (8371042-9)
on May 14, 2012 Female from GERMANY , 48 years of age, weighting 134.5 lb, was diagnosed with
  • malignant melanoma
and was treated with Ipilimumab. Directly after, patient experienced the unwanted or unexpected Ipilimumab side effects: vomiting, emotional distress, neoplasm malignant, colitis, diarrhoea, abdominal pain upper, polyneuropathy. Ipilimumab dosage: No Of Doses 3,2nd On 18jul11. Patient was hospitalized.


Nausea, Diarrhoea (8370181-6)
on May 10, 2012 Male from UNITED STATES , 64 years of age, weighting 202.8 lb, was diagnosed with
  • malignant melanoma
and was treated with Ipilimumab. Patient felt the following Ipilimumab side effects: nausea, diarrhoea. Ipilimumab dosage: Last Dose On 06apr2012,4may12. Patient was hospitalized.

Anaemia (8370179-8)
Patient was taking Ipilimumab. After Ipilimumab was administered, patient encountered several Ipilimumab side effects: anaemia on May 10, 2012 from INDIA Additional patient health information: Male , 46 years of age, was diagnosed with
  • malignant melanoma
and. Ipilimumab dosage: N/A. Patient was hospitalized.

Metastatic Malignant Melanoma, Pain, Hepatotoxicity, Respiratory Failure, Condition Aggravated, Cellulitis, No Therapeutic Response, Neoplasm Progression, Hypotension (8365920-4)
Adverse event was reported on May 15, 2012 by a Male taking Ipilimumab -yervoy- 200mg/40ml Bristol-myers Squibb (Dosage: 10 Mg Per Kg Every 3 Weeks Iv Drip) was diagnosed with
  • metastatic malignant melanoma
and. Location: UNITED STATES , weighting 173.9 lb, Directly after, patient experienced the unwanted or unexpected Ipilimumab side effects: metastatic malignant melanoma, pain, hepatotoxicity, respiratory failure, condition aggravated, cellulitis, no therapeutic response, neoplasm progression, hypotension.
Associated medications used:
  • Dacarbazine


Multi-organ Failure, Nausea (8364137-7)
on May 10, 2012 Female from GERMANY , 80 years of age, weighting 154.3 lb, was diagnosed with
  • malignant melanoma
and was treated with Ipilimumab. Patient felt the following Ipilimumab side effects: multi-organ failure, nausea. Ipilimumab dosage: N/A.
Multiple prescriptions taken:
  • Dexamethasone
  • Torsemide
  • Haloperidol
  • Sodium Chloride (1df= 0.9%)
  • Pantoprazole
  • Dimenhydrinate
Patient was hospitalized.

Embolism, Fatigue, Hypotension, Neoplasm Malignant (8364136-5)
on May 07, 2012 Male from UNITED STATES , 61 years of age, weighting 158.7 lb, was diagnosed with
  • malignant melanoma
and was treated with Ipilimumab. After Ipilimumab was administered, patient encountered several Ipilimumab side effects: embolism, fatigue, hypotension, neoplasm malignant. Ipilimumab dosage: Day 1 C3 Delayed Until 01sep11 Start Dt:1sep11 Last Dose:1sep11 Resumed On 22sep11.
Multiple concurrent drugs taken:
  • Leukine (C3 Delayed Until 01sep11 Start Dt:1sep11 Last Dose:14sep11(3500mcg) Resumed On 22sep11)
Patient was hospitalized.

Abdominal Pain Upper, Emotional Distress, Polyneuropathy, Diarrhoea, Vomiting, Neoplasm Malignant, Colitis (8357806-6)
Patient was taking Ipilimumab. Directly after, patient experienced the unwanted or unexpected Ipilimumab side effects: abdominal pain upper, emotional distress, polyneuropathy, diarrhoea, vomiting, neoplasm malignant, colitis on May 08, 2012 from GERMANY Additional patient health information: Female , 48 years of age, weighting 134.5 lb, was diagnosed with
  • malignant melanoma
and. Ipilimumab dosage: No Of Doses 3,2nd On 18jul11. Patient was hospitalized.

Pulmonary Alveolar Haemorrhage, Diarrhoea, Vomiting (8357126-X)
Adverse event was reported on May 03, 2012 by a Male taking Ipilimumab (Dosage: N/A) was diagnosed with
  • malignant melanoma
and. Location: SPAIN , 79 years of age, Patient felt the following Ipilimumab side effects: pulmonary alveolar haemorrhage, diarrhoea, vomiting.
Multiple prescriptions taken:
  • Enoxaparin Sodium
  • Digoxin
  • Acetaminophen
  • Astudal
  • Bisoprolol Fumarate
  • Zolpidem Tartrate
  • Omeprazole
  • Tranxilium
Patient was hospitalized.

Headache (8351023-1)
on May 04, 2012 Male from UNITED STATES , 55 years of age, weighting 244.7 lb, was diagnosed with
  • malignant melanoma
and was treated with Ipilimumab. After Ipilimumab was administered, patient encountered several Ipilimumab side effects: headache. Ipilimumab dosage: Last Dose:21dec11, Removed From Protocol On 15feb12. Patient was hospitalized.

Myalgia, Arthralgia (8350443-9)
on May 01, 2012 Male from UNITED STATES , 66 years of age, weighting 183.0 lb, was diagnosed with
  • malignant melanoma
and was treated with Ipilimumab. Directly after, patient experienced the unwanted or unexpected Ipilimumab side effects: myalgia, arthralgia. Ipilimumab dosage: Last Dose:28mar12 838mg Week 7.

Pancytopenia, Diarrhoea Haemorrhagic, Neoplasm Progression, Colitis (8347969-0)
Patient was taking Ipilimumab. Patient felt the following Ipilimumab side effects: pancytopenia, diarrhoea haemorrhagic, neoplasm progression, colitis on May 04, 2012 from UNITED STATES Additional patient health information: Female , 59 years of age, was diagnosed with
  • metastasis
and. Ipilimumab dosage: 3 Mg/kg, Unk.
Multiple prescriptions taken:
  • Gemzar


Anaemia (8347857-X)
Adverse event was reported on Apr 27, 2012 by a Female taking Ipilimumab (Dosage: Course 4) was diagnosed with
  • malignant melanoma
and. Location: INDIA , 57 years of age, After Ipilimumab was administered, patient encountered several Ipilimumab side effects: anaemia. Patient was hospitalized.

Colitis, Female Genital Tract Fistula (8347583-7)
on Apr 28, 2012 Female from UNITED STATES , 57 years of age, weighting 187.4 lb, was diagnosed with
  • malignant melanoma
and was treated with Ipilimumab. Directly after, patient experienced the unwanted or unexpected Ipilimumab side effects: colitis, female genital tract fistula. Ipilimumab dosage: Number Of Courses:3.last Dose On 16mar12.. Patient was hospitalized.

Upper Respiratory Tract Infection (8344718-7)
on Apr 27, 2012 Male from UNITED STATES , 13 years of age, weighting 94.80 lb, was diagnosed with
  • malignant melanoma
and was treated with Ipilimumab. Patient felt the following Ipilimumab side effects: upper respiratory tract infection. Ipilimumab dosage: Last Dose 11apr12.. Patient was hospitalized.

Gallbladder Perforation, Cholangitis (8338378-9)
Patient was taking Ipilimumab. After Ipilimumab was administered, patient encountered several Ipilimumab side effects: gallbladder perforation, cholangitis on Apr 24, 2012 from UNITED KINGDOM Additional patient health information: Male , 69 years of age, was diagnosed with
  • prostate cancer
and. Ipilimumab dosage: 1df=730 Units Not Specified Dose:1440 Units Nos 2inj. Patient was hospitalized.

Vomiting, Diarrhoea, Dehydration, Toxicity To Various Agents, Enterocolitis (8338201-2)
Adverse event was reported on Apr 26, 2012 by a Male taking Ipilimumab (Dosage: Last Administered Dose:29feb2012.) was diagnosed with
  • bone sarcoma
and. Location: UNITED STATES , 15 years of age, weighting 112.4 lb, Directly after, patient experienced the unwanted or unexpected Ipilimumab side effects: vomiting, diarrhoea, dehydration, toxicity to various agents, enterocolitis. Patient was hospitalized.

Headache (8336514-1)
on Apr 24, 2012 Female from BELGIUM , 58 years of age, was diagnosed with
  • malignant melanoma
and was treated with Ipilimumab. Patient felt the following Ipilimumab side effects: headache. Ipilimumab dosage: Inter On:30mar12. Patient was hospitalized.

Urinary Tract Infection, Pyrexia, Staphylococcal Infection (8330164-9)
on Apr 21, 2012 Male from UNITED STATES , 54 years of age, weighting 167.6 lb, was diagnosed with
  • malignant melanoma
and was treated with Ipilimumab. After Ipilimumab was administered, patient encountered several Ipilimumab side effects: urinary tract infection, pyrexia, staphylococcal infection. Ipilimumab dosage: N/A. Patient was hospitalized.

Thrombocytopenia, Pancytopenia, Eosinophilia, Neoplasm Malignant, Diarrhoea (8328595-6)
Patient was taking Ipilimumab. Directly after, patient experienced the unwanted or unexpected Ipilimumab side effects: thrombocytopenia, pancytopenia, eosinophilia, neoplasm malignant, diarrhoea on Apr 20, 2012 from FRANCE Additional patient health information: Female , 60 years of age, weighting 134.5 lb, was diagnosed with
  • malignant melanoma
and. Ipilimumab dosage: Batch # 0c62102.om. Patient was hospitalized.

Uveitis, Pneumonitis (8315786-3)
Adverse event was reported on Apr 24, 2012 by a Male taking Ipilimumab (Dosage: N/A) was diagnosed with
  • malignant melanoma
  • hypercholesterolaemia
  • constipation prophylaxis
and. Location: UNITED STATES , 79 years of age, Patient felt the following Ipilimumab side effects: uveitis, pneumonitis.
Multiple prescriptions taken:
  • Simvastatin
  • Colace
  • Prednisone
  • Senna (3tabs:19jan12-8feb12 2 Tabs:8feb12-ong)
  • Aspirin (81 Mg)
  • Miralax (1df= 1capful.)
  • Oxycodone Hcl (Prn For Pain Q6 Hrs Prn)
  • Mdx-1106
Patient was hospitalized.

Rash Maculo-papular, Adhesion, Ileus, Carcinoid Tumour Of The Appendix, Small Intestinal Obstruction (8310242-0)
on Apr 13, 2012 Male from UNITED STATES , 56 years of age, weighting 229.3 lb, was diagnosed with
  • malignant melanoma
and was treated with Ipilimumab. After Ipilimumab was administered, patient encountered several Ipilimumab side effects: rash maculo-papular, adhesion, ileus, carcinoid tumour of the appendix, small intestinal obstruction. Ipilimumab dosage: Last Dose On 12mar12,no Of Courses: 4. Patient was hospitalized.

Nausea, Pyrexia, Alopecia, Vitiligo, Vomiting, Hypophysitis, Hyperthyroidism, Abdominal Pain (8310237-7)
on Apr 14, 2012 Male from POLAND , 54 years of age, was diagnosed with
  • malignant melanoma
and was treated with Ipilimumab. Directly after, patient experienced the unwanted or unexpected Ipilimumab side effects: nausea, pyrexia, alopecia, vitiligo, vomiting, hypophysitis, hyperthyroidism, abdominal pain. Ipilimumab dosage: 2nd Dose:16aug11,265mg 3rd Dose:08sep11,270mg. Patient was hospitalized.

  Showing 51-75 of 617 

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Ipilimumab Information

More About Ipilimumab

Side Effects reported to FDA: 617. View Ipilimumab Adverse Reports

Ipilimumab safety alerts: 2011

Reported deaths: 132

Reported hospitalizations: 517

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